Molecular enhancement of porcine cardiac chronotropy

Heart

Volumn 86, Issue 5, 2001, Pages 559-562

  Edelberg, J M ^a   Huang, D T ^a   Josephson, M E ^a   Rosenberg, R D ^b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Adrenergic receptor; Chronotropic agents; Conduction system; Gene therapy; Sinus node

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONOTROPISM; CONTROLLED STUDY; FEASIBILITY STUDY; FEMALE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HEART ARRHYTHMIA; HEART CONDUCTION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE; HEART MUSCLE POTENTIAL; HEART RATE; HEART RIGHT ATRIUM; NONHUMAN; PLASMID; PRIORITY JOURNAL; SINUS NODE; SWINE; TREATMENT OUTCOME;

EID: 0034773335     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/heart.86.5.559     Document Type: Article

References (36)

1. Pacing for carotid sinus syndrome and sick sinus syndrome
2. Heart rate responses to autonomic drugs in sick sinus syndrome: Correlation with syncope and electrophysiologic data
3. Update on sick sinus syndrome, a cardiac disorder of aging
4. Postextrasystolic sinoatrial exit block in human sick sinus syndrome: Demonstration by direct recording of sinus node electrograms
5. Sinus automaticity and sinoatrial conduction in severe symptomatic sick sinus syndrome
6. Primary sick sinus syndrome as an indication for chronic pacemaker therapy in young adults: Incidence, clinical features, and long-term evaluation
7. Symptomatic sinus node dysfunction in children without structural heart disease
8. The sick sinus syndrome in familial amyloidosis with polyneuropathy
9. Familial sinus node disease and degenerative myopia: A new hereditary syndrome?
10. Familial symptomatic sinus bradycardia: Autosomal dominant inheritance
11. Quantitative histological analysis of the human sinoatrial node during growth and aging
12. The pathologic changes in the conduction system beyond the age of ninety
13. Chronic sinoatrial disorder (sick sinus syndrome): A possible result of cardiac ischaemia
14. Cardiac autonomic dysfunction and neuroganglionitis in a rat model of chronic Chagas' disease
15. Histopathology of the heart conducting system in experimental Chagas disease in mice
16. Effects of permanent pacemaker and oral theophylline in sick sinus syndrome the THEOPACE study: A randomized controlled trial
17. Advances in pacing for the patient with sick sinus syndrome
18. Gene therapy for vascular disease
19. Gene therapy of restenosis: Promise and perils
20. Enhancement of murine cardiac chronotropy by the molecular transfer of the human beta2 adrenergic receptor cDNA
21. Swine in cardiovascular research
22. Codon usage limitation in the expression of HIV-1 envelope glycoprotein
23. A novel method for nonfluoroscopic catheter-based electroanatomical mapping of the heart: In vitro and in vivo accuracy results
24. The effects of desflurane on cardiac function as measured by conductance volumetry in swine
25. Disparity of isoflurane effects on left and right ventricular afterload and hydraulic power generation in swine
26. Expression of recombinant genes in myocardium in vivo after direct injection of DNA
27. Behavior of genes directly injected into the rat heart in vivo
28. Conditions affecting direct gene transfer into rodent muscle in vivo
29. Gene injection into canine myocardium as a useful model for studying gene expression in the heart of large mammals
30. Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle
31. Quantitative analysis of regional variability in the distribution of transverse tubules in rabbit myocardium
32. Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo
33. Cardiac gene transfer by intracoronary infusion of adenovirus vector-mediated reporter gene in the transplanted mouse heart
34. Adenovirus-mediated expression of a voltage-gated potassium channel in vitro (rat cardiac myocytes) and in vivo (rat liver): A novel strategy for modifying excitability
35. Stable fetal cardiomyocyte grafts in the hearts of dystrophic mice and dogs
36. Survival of grafts of genetically modified cardiac myocytes transfected with FITC-labeled oligodeoxynucleotides and the beta-galactosidase gene in the noninfarcted area, but not the myocardial infarcted area