Human Mesenchymal Stem Cells as a Gene Delivery System to Create Cardiac Pacemakers

Circulation Research

Volumn 94, Issue 7, 2004, Pages 952-959

  Potapova, Irina ^a   Plotnikov, Alexei ^b   Lu, Zhongju ^a   Danilo Jr , Peter ^b   Valiunas, Virginijus ^a   Qu, Jihong ^b   Doronin, Sergey ^a   Zuckerman, Joan ^a   Shlapakova, Iryna N ^b   Gao, Junyuan ^a   Pan, Zongming ^a   Herron, Alan J ^b   Robinson, Richard B ^b   Brink, Peter R ^a   Rosen, Michael R ^b   Cohen, Ira S ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Gene therapy; Heart block; Ion channels; Pacemakers; Stem cells

Indexed keywords

ACETYLCHOLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; ISOPRENALINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; COCULTURE; CONTROLLED STUDY; DNA MODIFICATION; DOG; ELECTRIC CURRENT; ELECTRIC POTENTIAL; ELECTROPORATION; EXPERIMENTAL MODEL; GAP JUNCTION; GENE CONSTRUCT; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HEART LEFT VENTRICLE WALL; HEART MUSCLE CELL; HEART RATE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MESENCHYME; NEWBORN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SINUS ARREST; SINUS NODE; SINUS RHYTHM; STEM CELL;

ACETYLCHOLINE; ADRENERGIC BETA-AGONISTS; ANIMALS; CELLS, CULTURED; CESIUM; CHOLINERGIC AGENTS; COCULTURE TECHNIQUES; DOGS; ELECTROPORATION; GAP JUNCTIONS; GENE THERAPY; HEART RATE; HEART VENTRICLES; HUMANS; ION CHANNELS; ION TRANSPORT; ISOPROTERENOL; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MICE; MUSCLE PROTEINS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; RATS; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 11144357199     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000123827.60210.72     Document Type: Article

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