메뉴 건너뛰기




Volumn 115, Issue 3, 2010, Pages 510-518

Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP1; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXP1 PROTEIN, MOUSE; REPRESSOR PROTEIN;

EID: 77449127289     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-07-232694     Document Type: Article
Times cited : (102)

References (49)
  • 2
    • 3142769748 scopus 로고    scopus 로고
    • CD4/CD8-lineage differentiation in the thymus: From nuclear effectors to membrane signals
    • Bosselut R. CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals. Nat Rev Immunol. 2004;4:529-540.
    • (2004) Nat Rev Immunol , vol.4 , pp. 529-540
    • Bosselut, R.1
  • 3
    • 0026044445 scopus 로고
    • The majority of CD4+8- Thymocytes are functionally immature
    • Ramsdell F, Jenkins M, Dinh Q, Fowlkes BJ. The majority of CD4+8- thymocytes are functionally immature. J Immunol. 1991;147:1779-1785.
    • (1991) J Immunol , vol.147 , pp. 1779-1785
    • Ramsdell, F.1    Jenkins, M.2    Dinh, Q.3    Fowlkes, B.J.4
  • 4
    • 53749107973 scopus 로고    scopus 로고
    • Negative regulators in homeostasis of naive peripheral T cells
    • Modiano JF, Johnson LD, Bellgrau D. Negative regulators in homeostasis of naive peripheral T cells. Immunol Res. 2008;41:137-153.
    • (2008) Immunol Res , vol.41 , pp. 137-153
    • Modiano, J.F.1    Johnson, L.D.2    Bellgrau, D.3
  • 5
    • 0035202540 scopus 로고    scopus 로고
    • Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells
    • Tzachanis D, Freeman GJ, Hirano N, et al. Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells. Nat Immunol. 2001;2:1174-1182.
    • (2001) Nat Immunol , vol.2 , pp. 1174-1182
    • Tzachanis, D.1    Freeman, G.J.2    Hirano, N.3
  • 6
    • 4544281491 scopus 로고    scopus 로고
    • Intrinsic and extrinsic regulation of T lymphocyte quiescence
    • Tzachanis D, Lafuente EM, Li L, Boussiotis VA. Intrinsic and extrinsic regulation of T lymphocyte quiescence. Leuk Lymphoma. 2004;45:1959-1967.
    • (2004) Leuk Lymphoma , vol.45 , pp. 1959-1967
    • Tzachanis, D.1    Lafuente, E.M.2    Li, L.3    Boussiotis, V.A.4
  • 7
    • 0033607212 scopus 로고    scopus 로고
    • Activation changes the spectrum but not the diversity of genes expressed by T cells
    • Teague TK, Hildeman D, Kedl RM, et al. Activation changes the spectrum but not the diversity of genes expressed by T cells. Proc Natl Acad Sci U S A. 1999;96:12691-12696.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12691-12696
    • Teague, T.K.1    Hildeman, D.2    Kedl, R.M.3
  • 8
    • 0028859281 scopus 로고
    • Selective requirement for MAP kinase activation in thymocyte differentiation
    • Alberola-Ila J, Forbush KA, Seger R, Krebs EG, Perlmutter RM. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature. 1995;373:620-623.
    • (1995) Nature , vol.373 , pp. 620-623
    • Alberola-Ila, J.1    Forbush, K.A.2    Seger, R.3    Krebs, E.G.4    Perlmutter, R.M.5
  • 9
    • 0034720881 scopus 로고    scopus 로고
    • A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity
    • Werlen G, Hausmann B, Palmer E. A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity. Nature. 2000;406:422-426.
    • (2000) Nature , vol.406 , pp. 422-426
    • Werlen, G.1    Hausmann, B.2    Palmer, E.3
  • 10
    • 0035229933 scopus 로고    scopus 로고
    • Disruption of T cell signaling networks and development by Grb2 haploid insufficiency
    • Gong Q, Cheng AM, Akk AM, et al. Disruption of T cell signaling networks and development by Grb2 haploid insufficiency. Nat Immunol. 2001;2:29-36.
    • (2001) Nat Immunol , vol.2 , pp. 29-36
    • Gong, Q.1    Cheng, A.M.2    Akk, A.M.3
  • 12
    • 0034326646 scopus 로고    scopus 로고
    • NF-kappa B is required for the positive selection of CD8+ thymocytes
    • Hettmann T, Leiden JM. NF-kappa B is required for the positive selection of CD8+ thymocytes. J Immunol. 2000;165:5004-5010.
    • (2000) J Immunol , vol.165 , pp. 5004-5010
    • Hettmann, T.1    Leiden, J.M.2
  • 13
    • 0032541312 scopus 로고    scopus 로고
    • Modulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1)
    • Miyazaki T, Lemonnier FA. Modulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1). J Exp Med. 1998;188:715-723.
    • (1998) J Exp Med , vol.188 , pp. 715-723
    • Miyazaki, T.1    Lemonnier, F.A.2
  • 14
    • 0037103324 scopus 로고    scopus 로고
    • Thymocyte development in early growth response gene 1-deficient mice
    • Bettini M, Xi H, Milbrandt J, Kersh GJ. Thymocyte development in early growth response gene 1-deficient mice. J Immunol. 2002;169:1713-1720.
    • (2002) J Immunol , vol.169 , pp. 1713-1720
    • Bettini, M.1    Xi, H.2    Milbrandt, J.3    Kersh, G.J.4
  • 15
    • 0033984819 scopus 로고    scopus 로고
    • Thymocyte selection is regulated by the helix-loop-helix inhibitor protein
    • Rivera RR, Johns CP, Quan J, Johnson RS, Murre C. Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. Immunity. 2000;12:17-26.
    • (2000) Id3. Immunity , vol.12 , pp. 17-26
    • Rivera, R.R.1    Johns, C.P.2    Quan, J.3    Johnson, R.S.4    Murre, C.5
  • 16
    • 0035170433 scopus 로고    scopus 로고
    • Murine Schnurri-2 is required for positive selection of thymocytes
    • Takagi T, Harada J, Ishii S. Murine Schnurri-2 is required for positive selection of thymocytes. Nat Immunol. 2001;2:1048-1053.
    • (2001) Nat Immunol , vol.2 , pp. 1048-1053
    • Takagi, T.1    Harada, J.2    Ishii, S.3
  • 17
    • 0035903286 scopus 로고    scopus 로고
    • Early thymocyte development is regulated by modulation of E2A protein activity
    • Engel I, Johns C, Bain G, Rivera RR, Murre C. Early thymocyte development is regulated by modulation of E2A protein activity. J Exp Med. 2001;194:733-745.
    • (2001) J Exp Med , vol.194 , pp. 733-745
    • Engel, I.1    Johns, C.2    Bain, G.3    Rivera, R.R.4    Murre, C.5
  • 18
    • 0030823769 scopus 로고    scopus 로고
    • LKLF: A transcriptional regulator of single-positive T cell quiescence and survival
    • Kuo CT, Veselits ML, Leiden JM. LKLF: A transcriptional regulator of single-positive T cell quiescence and survival. Science. 1997;277:1986-1990.
    • (1997) Science , vol.277 , pp. 1986-1990
    • Kuo, C.T.1    Veselits, M.L.2    Leiden, J.M.3
  • 19
    • 33746334804 scopus 로고    scopus 로고
    • Kruppel-like factor 2 regulates thymocyte and T-cell migration
    • Carlson CM, Endrizzi BT, Wu J, et al. Kruppel-like factor 2 regulates thymocyte and T-cell migration. Nature. 2006;442:299-302.
    • (2006) Nature , vol.442 , pp. 299-302
    • Carlson, C.M.1    Endrizzi, B.T.2    Wu, J.3
  • 20
    • 39449087305 scopus 로고    scopus 로고
    • Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns
    • Sebzda E, Zou Z, Lee JS, Wang T, Kahn ML. Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns. Nat Immunol. 2008;9:292-300.
    • (2008) Nat Immunol , vol.9 , pp. 292-300
    • Sebzda, E.1    Zou, Z.2    Lee, J.S.3    Wang, T.4    Kahn, M.L.5
  • 21
    • 0036387193 scopus 로고    scopus 로고
    • Forkhead transcription factors: Key players in development and meolism
    • Carlsson P, Mahlapuu M. Forkhead transcription factors: key players in development and meolism. Dev Biol. 2002;250:1-23.
    • (2002) Dev Biol , vol.250 , pp. 1-23
    • Carlsson, P.1    Mahlapuu, M.2
  • 22
    • 0028000121 scopus 로고
    • New member of the winged-helix protein family disrupted in mouse and rat nude mutations
    • Nehls M, Pfeifer D, Schorpp M, Hedrich H, Boehm T. New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature. 1994;372:103-107.
    • (1994) Nature , vol.372 , pp. 103-107
    • Nehls, M.1    Pfeifer, D.2    Schorpp, M.3    Hedrich, H.4    Boehm, T.5
  • 23
    • 1142286333 scopus 로고    scopus 로고
    • Modulation of Th1 activation and inflammation by the NF-kappaB repressor Foxj1
    • Lin L, Spoor MS, Gerth AJ, Brody SL, Peng SL. Modulation of Th1 activation and inflammation by the NF-kappaB repressor Foxj1. Science. 2004;303:1017-1020.
    • (2004) Science , vol.303 , pp. 1017-1020
    • Lin, L.1    Spoor, M.S.2    Gerth, A.J.3    Brody, S.L.4    Peng, S.L.5
  • 24
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 25
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol. 2003;4:330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 26
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol. 2003;4:337-342.
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 27
    • 44049091757 scopus 로고    scopus 로고
    • Foxo1 directly regulates the transcription of recombination-activating genes during B cell development
    • Amin RH, Schlissel MS. Foxo1 directly regulates the transcription of recombination-activating genes during B cell development. Nat Immunol. 2008;9:613-622.
    • (2008) Nat Immunol , vol.9 , pp. 613-622
    • Amin, R.H.1    Schlissel, M.S.2
  • 28
    • 56349127778 scopus 로고    scopus 로고
    • Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation
    • Dengler HS, Baracho GV, Omori SA, et al. Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation. Nat Immunol. 2008;9:1388-1398.
    • (2008) Nat Immunol , vol.9 , pp. 1388-1398
    • Dengler, H.S.1    Baracho, G.V.2    Omori, S.A.3
  • 29
    • 58449102260 scopus 로고    scopus 로고
    • Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor
    • Kerdiles YM, Beisner DR, Tinoco R, et al. Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nat Immunol. 2009;10:176-184.
    • (2009) Nat Immunol , vol.10 , pp. 176-184
    • Kerdiles, Y.M.1    Beisner, D.R.2    Tinoco, R.3
  • 30
    • 62049086102 scopus 로고    scopus 로고
    • An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance
    • Ouyang W, Beckett O, Flavell RA, Li MO. An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance. Immunity. 2009;30:358-371.
    • (2009) Immunity , vol.30 , pp. 358-371
    • Ouyang, W.1    Beckett, O.2    Flavell, R.A.3    Li, M.O.4
  • 31
    • 0027133451 scopus 로고
    • DNA-binding properties and secondary structural model of the hepatocyte nuclear factor 3/fork head domain
    • Li C, Tucker PW. DNA-binding properties and secondary structural model of the hepatocyte nuclear factor 3/fork head domain. Proc Natl Acad Sci U S A. 1993;90:11583-11587.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 11583-11587
    • Li, C.1    Tucker, P.W.2
  • 32
    • 33746150775 scopus 로고    scopus 로고
    • Foxp1 is an essential transcriptional regulator of B cell development
    • Hu H, Wang B, Borde M, et al. Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol. 2006;7:819-826.
    • (2006) Nat Immunol , vol.7 , pp. 819-826
    • Hu, H.1    Wang, B.2    Borde, M.3
  • 33
    • 0035920153 scopus 로고    scopus 로고
    • Characterization of a new subfamily of wingedhelix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors
    • Shu W, Yang H, Zhang L, Lu MM, Morrisey EE. Characterization of a new subfamily of wingedhelix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors. J Biol Chem. 2001;276:27488-27497.
    • (2001) J Biol Chem , vol.276 , pp. 27488-27497
    • Shu, W.1    Yang, H.2    Zhang, L.3    Lu, M.M.4    Morrisey, E.E.5
  • 34
    • 6944232153 scopus 로고    scopus 로고
    • Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation
    • Wang B, Weidenfeld J, Lu MM, et al. Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation. Development. 2004;131:4477-4487.
    • (2004) Development , vol.131 , pp. 4477-4487
    • Wang, B.1    Weidenfeld, J.2    Lu, M.M.3
  • 35
    • 58149386502 scopus 로고    scopus 로고
    • Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function
    • Shi C, Sakuma M, Mooroka T, et al. Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function. Blood. 2008;112:4699-4711.
    • (2008) Blood , vol.112 , pp. 4699-4711
    • Shi, C.1    Sakuma, M.2    Mooroka, T.3
  • 36
    • 18244365863 scopus 로고    scopus 로고
    • A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
    • Lee PP, Fitzpatrick DR, Beard C, et al. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity. 2001;15:763-774.
    • (2001) Immunity , vol.15 , pp. 763-774
    • Lee, P.P.1    Fitzpatrick, D.R.2    Beard, C.3
  • 37
    • 0031884839 scopus 로고    scopus 로고
    • The duration of antigenic stimulation determines the fate of naive and effector T cells
    • Iezzi G, Karjalainen K, Lanzavecchia A. The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity. 1998;8:89-95.
    • (1998) Immunity , vol.8 , pp. 89-95
    • Iezzi, G.1    Karjalainen, K.2    Lanzavecchia, A.3
  • 38
    • 0028229558 scopus 로고
    • Production, selection, and maturation of thymocytes with high surface density of TCR
    • Lucas B, Vasseur F, Penit C. Production, selection, and maturation of thymocytes with high surface density of TCR. J Immunol. 1994;153:53-62.
    • (1994) J Immunol , vol.153 , pp. 53-62
    • Lucas, B.1    Vasseur, F.2    Penit, C.3
  • 40
    • 0027491845 scopus 로고
    • CD44 and its interaction with extracellular matrix
    • Lesley J, Hyman R, Kincade PW. CD44 and its interaction with extracellular matrix. Adv Immunol. 1993;54:271-335.
    • (1993) Adv Immunol , vol.54 , pp. 271-335
    • Lesley, J.1    Hyman, R.2    Kincade, P.W.3
  • 41
    • 0042591396 scopus 로고    scopus 로고
    • Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors
    • Wang B, Lin D, Li C, Tucker P. Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors. J Biol Chem. 2003;278:24259-24268.
    • (2003) J Biol Chem , vol.278 , pp. 24259-24268
    • Wang, B.1    Lin, D.2    Li, C.3    Tucker, P.4
  • 42
    • 0030014002 scopus 로고    scopus 로고
    • T-cell-receptor affinity and thymocyte positive selection
    • Alam SM, Travers PJ, Wung JL, et al. T-cell-receptor affinity and thymocyte positive selection. Nature. 1996;381:616-620.
    • (1996) Nature , vol.381 , pp. 616-620
    • Alam, S.M.1    Travers, P.J.2    Wung, J.L.3
  • 44
    • 0033577859 scopus 로고    scopus 로고
    • A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex
    • Williams CB, Engle DL, Kersh GJ, Michael White J, Allen PM. A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex. J Exp Med. 1999;189:1531-1544.
    • (1999) J Exp Med , vol.189 , pp. 1531-1544
    • Williams, C.B.1    Engle, D.L.2    Kersh, G.J.3    Michael White, J.4    Allen, P.M.5
  • 45
    • 0032445491 scopus 로고    scopus 로고
    • CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity
    • Azzam HS, Grinberg A, Lui K, Shen H, Shores EW, Love PE. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity. J Exp Med. 1998;188:2301-2311.
    • (1998) J Exp Med , vol.188 , pp. 2301-2311
    • Azzam, H.S.1    Grinberg, A.2    Lui, K.3    Shen, H.4    Shores, E.W.5    Love, P.E.6
  • 46
    • 51549111249 scopus 로고    scopus 로고
    • FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase
    • Fabre S, Carrette F, Chen J, et al. FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase. J Immunol. 2008;181:2980-2989.
    • (2008) J Immunol , vol.181 , pp. 2980-2989
    • Fabre, S.1    Carrette, F.2    Chen, J.3
  • 47
    • 0036342071 scopus 로고    scopus 로고
    • Positive selection of MHC class Ib-restricted CD8(+) T cells on hematopoietic cells
    • Urdahl KB, Sun JC, Bevan MJ. Positive selection of MHC class Ib-restricted CD8(+) T cells on hematopoietic cells. Nat Immunol. 2002;3:772-779.
    • (2002) Nat Immunol , vol.3 , pp. 772-779
    • Urdahl, K.B.1    Sun, J.C.2    Bevan, M.J.3
  • 48
    • 0027286575 scopus 로고
    • Intestinal intraepithelial lymphocytes are activated and cytolytic but do not proliferate as well as other T cells in response to mitogenic signals
    • Sydora BC, Mixter PF, Holcombe HR, et al. Intestinal intraepithelial lymphocytes are activated and cytolytic but do not proliferate as well as other T cells in response to mitogenic signals. J Immunol. 1993;150:2179-2191.
    • (1993) J Immunol , vol.150 , pp. 2179-2191
    • Sydora, B.C.1    Mixter, P.F.2    Holcombe, H.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.