Effects of oxygenation and flow on the viability and function of rat hepatocytes cocultured in a microchannel flat-plate bioreactor

Biotechnology and Bioengineering

Volumn 73, Issue 5, 2001, Pages 379-389

  Tilles, Arno W ^a   Baskaran, Harihara ^a   Roy, Partha ^a   Yarmush, Martin L ^a   Toner, Mehmet ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Bioartificial liver; Flat plate; Microfabrication; Perfusion; Shear stress

Indexed keywords

BIOREACTORS; OXYGENATORS; SHEAR STRESS; UREA;

FIBROPLASTS;

BIOTECHNOLOGY;

ANIMAL CELL; ARTICLE; ARTIFICIAL LIVER; BIOREACTOR; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; EXTRACORPOREAL OXYGENATION; FEMALE; LIVER CELL CULTURE; MATHEMATICAL MODEL; NONHUMAN; OXYGENATION; OXYGENATOR; PERFUSION; PROTEIN SYNTHESIS; RAT; SHEAR STRESS; UREA CYCLE;

3T3 CELLS; ANIMALS; BIOREACTORS; CELL SURVIVAL; COCULTURE TECHNIQUES; FEMALE; HEPATOCYTES; MICE; OXYGEN; RATS; RATS, INBRED LEW;

EID: 0035811241     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.1071     Document Type: Article

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