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Volumn 18, Issue 12, 2009, Pages 1319-1340

Sequential hepatogenic transdifferentiation of adipose tissue-derived stem cells: Relevance of different extracellular signaling molecules, transcription factors involved, and expression of new key marker genes

Author keywords

Adipose tissue; Hepatocyte differentiation; Mesenchymal stem cell; Transcription factors

Indexed keywords

ALBUMIN; ALPHA 2 MACROGLOBULIN; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; BIOCHEMICAL MARKER; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; COMPLEMENT COMPONENT C3; CYTOCHROME P450 3A4; CYTOKINE; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 4; FRUCTOSE BISPHOSPHATE ALDOLASE; GROWTH FACTOR; HORMONE; INSULIN; LONG CHAIN FATTY ACID COENZYME A LIGASE; NICOTINAMIDE; ONCOSTATIN M; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); SCATTER FACTOR; SELENIUM; SELENOPROTEIN P; THY 1 ANTIGEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 6; TRANSFERRIN;

EID: 77349110490     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368909X12483162197321     Document Type: Article
Times cited : (41)

References (102)
  • 1
    • 47949092668 scopus 로고    scopus 로고
    • Efficient differentiation of functional hepatocytes from human embryonic stem cells
    • Agarwal, S.; Holton, K. L.; Lanza, R. Efficient differentiation of functional hepatocytes from human embryonic stem cells. Stem Cells 26(5):1117-1127; 2008.
    • (2008) Stem Cells , vol.26 , Issue.5 , pp. 1117-1127
    • Agarwal, S.1    Holton, K.L.2    Lanza, R.3
  • 2
    • 0030663731 scopus 로고    scopus 로고
    • Two hepatic enhancers, HCR.1 and HCR.2, coordinate the liver expression of the entire human apolipoprotein E/C-I/C-IV/C-II gene cluster
    • Allan, C. M.; Taylor, S.; Taylor, J. M. Two hepatic enhancers, HCR.1 and HCR.2, coordinate the liver expression of the entire human apolipoprotein E/C-I/C-IV/C-II gene cluster. J. Biol. Chem. 272(46):29113-29119; 1997.
    • (1997) J. Biol. Chem , vol.272 , Issue.46 , pp. 29113-29119
    • Allan, C.M.1    Taylor, S.2    Taylor, J.M.3
  • 4
    • 53949120786 scopus 로고    scopus 로고
    • IFATS collection: In vivo therapeutic potential of human adipose tissue mesenchymal stem cells (AT-MSCs) after transplantation into mice with liver injury
    • Banas, A.; Teratani, T.; Yamamoto, Y.; Tokuhara, M.; Takeshita, F.; Osaki, M.; Kawamata, M.; Kato, T.; Okochi, H.; Ochiya, T. IFATS collection: In vivo therapeutic potential of human adipose tissue mesenchymal stem cells (AT-MSCs) after transplantation into mice with liver injury. Stem Cells 26(10):2705-2712; 2008.
    • (2008) Stem Cells , vol.26 , Issue.10 , pp. 2705-2712
    • Banas, A.1    Teratani, T.2    Yamamoto, Y.3    Tokuhara, M.4    Takeshita, F.5    Osaki, M.6    Kawamata, M.7    Kato, T.8    Okochi, H.9    Ochiya, T.10
  • 6
    • 33746974304 scopus 로고    scopus 로고
    • Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development
    • Beaudry, J. B.; Pierreux, C. E.; Hayhurst, G. P.; Plumb-Rudewiez, N.; Weiss, M. C.; Rousseau, G. G.; Lemaigre, F. P. Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development. Mol. Cell. Biol. 26(16):6037-6046; 2006.
    • (2006) Mol. Cell. Biol , vol.26 , Issue.16 , pp. 6037-6046
    • Beaudry, J.B.1    Pierreux, C.E.2    Hayhurst, G.P.3    Plumb-Rudewiez, N.4    Weiss, M.C.5    Rousseau, G.G.6    Lemaigre, F.P.7
  • 7
    • 30544442260 scopus 로고    scopus 로고
    • Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development
    • Bort, R.; Signore, M.; Tremblay, K.; Martinez Barbera, J. P.; Zaret, K. S. Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development. Dev. Biol. 290(1):44-56; 2006.
    • (2006) Dev. Biol , vol.290 , Issue.1 , pp. 44-56
    • Bort, R.1    Signore, M.2    Tremblay, K.3    Martinez Barbera, J.P.4    Zaret, K.S.5
  • 9
    • 0030915005 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer into human hepatocytes: Analysis of the biochemical functionality of transduced cells
    • Castell, J. V.; Hernandez, D.; Gomez-Foix, A. M.; Guillen, I.; Donato, T.; Gomez-Lechon, M. J. Adenovirus-mediated gene transfer into human hepatocytes: Analysis of the biochemical functionality of transduced cells. Gene Ther. 4(5):455-464; 1997.
    • (1997) Gene Ther , vol.4 , Issue.5 , pp. 455-464
    • Castell, J.V.1    Hernandez, D.2    Gomez-Foix, A.M.3    Guillen, I.4    Donato, T.5    Gomez-Lechon, M.J.6
  • 10
    • 0037621983 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor (HNF)-4alpha triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells
    • Chiba, H.; Gotoh, T.; Kojima, T.; Satohisa, S.; Kikuchi, K.; Osanai, M.; Sawada, N. Hepatocyte nuclear factor (HNF)-4alpha triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells. Exp. Cell Res. 286(2):288-297; 2003.
    • (2003) Exp. Cell Res , vol.286 , Issue.2 , pp. 288-297
    • Chiba, H.1    Gotoh, T.2    Kojima, T.3    Satohisa, S.4    Kikuchi, K.5    Osanai, M.6    Sawada, N.7
  • 11
    • 0026668533 scopus 로고
    • Differential proliferative response of cultured fetal and regenerating hepatocytes to growth factors and hormones
    • de Juan, C.; Benito, M.; Alvarez, A.; Fabregat, I. Differential proliferative response of cultured fetal and regenerating hepatocytes to growth factors and hormones. Exp. Cell Res. 202(2):495-500; 1992.
    • (1992) Exp. Cell Res , vol.202 , Issue.2 , pp. 495-500
    • de Juan, C.1    Benito, M.2    Alvarez, A.3    Fabregat, I.4
  • 13
    • 34547808117 scopus 로고    scopus 로고
    • Thy-1 is an in vivo and in vitro marker of liver myofibroblasts
    • Dudas, J.; Mansuroglu, T.; Batusic, D.; Saile, B.; Ramadori, G. Thy-1 is an in vivo and in vitro marker of liver myofibroblasts. Cell Tissue Res. 329(3):503-514; 2007.
    • (2007) Cell Tissue Res , vol.329 , Issue.3 , pp. 503-514
    • Dudas, J.1    Mansuroglu, T.2    Batusic, D.3    Saile, B.4    Ramadori, G.5
  • 14
    • 0037213346 scopus 로고    scopus 로고
    • Mechanisms controlling early development of the liver
    • Duncan, S. A. Mechanisms controlling early development of the liver. Mech. Dev. 120(1):19-33; 2003.
    • (2003) Mech. Dev , vol.120 , Issue.1 , pp. 19-33
    • Duncan, S.A.1
  • 15
    • 0032584567 scopus 로고    scopus 로고
    • Regulation of a transcription factor network required for differentiation and metabolism
    • Duncan, S. A.; Navas, M. A.; Dufort, D.; Rossant, J.; Stoffel, M. Regulation of a transcription factor network required for differentiation and metabolism. Science 281(5377):692-695; 1998.
    • (1998) Science , vol.281 , Issue.5377 , pp. 692-695
    • Duncan, S.A.1    Navas, M.A.2    Dufort, D.3    Rossant, J.4    Stoffel, M.5
  • 17
    • 0034079140 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells in human umbilical cord blood
    • Erices, A.; Conget, P.; Minguell, J. J. Mesenchymal progenitor cells in human umbilical cord blood. Br. J. Haematol. 109(1):235-242; 2000.
    • (2000) Br. J. Haematol , vol.109 , Issue.1 , pp. 235-242
    • Erices, A.1    Conget, P.2    Minguell, J.J.3
  • 20
    • 16644388698 scopus 로고    scopus 로고
    • Issues in stem cell plasticity
    • Filip, S.; English, D.; Mokry, J. Issues in stem cell plasticity. J. Cell. Mol. Med. 8(4):572-577; 2004.
    • (2004) J. Cell. Mol. Med , vol.8 , Issue.4 , pp. 572-577
    • Filip, S.1    English, D.2    Mokry, J.3
  • 21
    • 0024725630 scopus 로고
    • CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells
    • Friedman, A. D.; Landschulz, W. H.; McKnight, S. L. CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells. Genes Dev. 3(9):1314-1322; 1989.
    • (1989) Genes Dev , vol.3 , Issue.9 , pp. 1314-1322
    • Friedman, A.D.1    Landschulz, W.H.2    McKnight, S.L.3
  • 22
    • 4644341747 scopus 로고    scopus 로고
    • Human hepatocytes in primary culture: The choice to investigate drug metabolism in man
    • Gómez-Lechón, M. J.; Donato, M. T.; Castell, J. V.; Jover, R. Human hepatocytes in primary culture: The choice to investigate drug metabolism in man. Curr. Drug Metab. 5(5):443-462; 2004.
    • (2004) Curr. Drug Metab , vol.5 , Issue.5 , pp. 443-462
    • Gómez-Lechón, M.J.1    Donato, M.T.2    Castell, J.V.3    Jover, R.4
  • 24
    • 0343431440 scopus 로고    scopus 로고
    • A microassay for measuring glycogen in 96-well-cultured cells
    • Gómez-Lechón, M. J.; Ponsoda, X.; Castell, J. V. A microassay for measuring glycogen in 96-well-cultured cells. Anal. Biochem. 236(2):296-301; 1996.
    • (1996) Anal. Biochem , vol.236 , Issue.2 , pp. 296-301
    • Gómez-Lechón, M.J.1    Ponsoda, X.2    Castell, J.V.3
  • 26
    • 39549105786 scopus 로고    scopus 로고
    • Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction
    • Hahn, J. Y.; Cho, H. J.; Kang, H. J.; Kim, T. S.; Kim, M. H.; Chung, J. H.; Bae, J. W.; Oh, B. H.; Park, Y. B.; Kim, H. S. Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction. J. Am. Coll. Cardiol. 51(9):933-943; 2008.
    • (2008) J. Am. Coll. Cardiol , vol.51 , Issue.9 , pp. 933-943
    • Hahn, J.Y.1    Cho, H.J.2    Kang, H.J.3    Kim, T.S.4    Kim, M.H.5    Chung, J.H.6    Bae, J.W.7    Oh, B.H.8    Park, Y.B.9    Kim, H.S.10
  • 27
    • 47749102180 scopus 로고    scopus 로고
    • Differentiation of osteoblasts and osteocytes from mesenchymal stem cells
    • Heino, T. J.; Hentunen, T. A. Differentiation of osteoblasts and osteocytes from mesenchymal stem cells. Curr. Stem Cell Res. Ther. 3(2):131-145; 2008.
    • (2008) Curr. Stem Cell Res. Ther , vol.3 , Issue.2 , pp. 131-145
    • Heino, T.J.1    Hentunen, T.A.2
  • 28
    • 11144291129 scopus 로고    scopus 로고
    • Isolation and characterization of mesenchymal progenitor cells from chorionic villi of human placenta
    • Igura, K.; Zhang, X.; Takahashi, K.; Mitsuru, A.; Yamaguchi, S.; Takashi, T. A. Isolation and characterization of mesenchymal progenitor cells from chorionic villi of human placenta. Cytotherapy 6(6):543-553; 2004.
    • (2004) Cytotherapy , vol.6 , Issue.6 , pp. 543-553
    • Igura, K.1    Zhang, X.2    Takahashi, K.3    Mitsuru, A.4    Yamaguchi, S.5    Takashi, T.A.6
  • 29
    • 33745857996 scopus 로고    scopus 로고
    • Isolation, characterization and culture of Thy1-positive cells from fetal rat livers
    • Isabel, Z.; Miri, B.; Einav, H.; Ella, B. L.; Zamir, H.; Ran, O. Isolation, characterization and culture of Thy1-positive cells from fetal rat livers. World J. Gastroenterol. 12(24):3841-3847; 2006.
    • (2006) World J. Gastroenterol , vol.12 , Issue.24 , pp. 3841-3847
    • Isabel, Z.1    Miri, B.2    Einav, H.3    Ella, B.L.4    Zamir, H.5    Ran, O.6
  • 30
    • 0029985185 scopus 로고    scopus 로고
    • Expression patterns of Id1, Id2, and Id3 are highly related but distinct from that of Id4 during mouse embryogenesis
    • Jen, Y.; Manova, K.; Benezra, R. Expression patterns of Id1, Id2, and Id3 are highly related but distinct from that of Id4 during mouse embryogenesis. Dev. Dyn. 207(3): 235-252; 1996.
    • (1996) Dev. Dyn , vol.207 , Issue.3 , pp. 235-252
    • Jen, Y.1    Manova, K.2    Benezra, R.3
  • 31
    • 0035124052 scopus 로고    scopus 로고
    • Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting
    • Jover, R.; Bort, R.; Gómez-Lechón, M. J.; Castell, J. V. Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting. Hepatology 33(3):668-675; 2001.
    • (2001) Hepatology , vol.33 , Issue.3 , pp. 668-675
    • Jover, R.1    Bort, R.2    Gómez-Lechón, M.J.3    Castell, J.V.4
  • 32
    • 0027536079 scopus 로고
    • Participation of the transcription factor C/EBP delta in the acute-phase regulation of the human gene for complement component C3
    • Juan, T. S.; Wilson, D. R.; Wilde, M. D.; Darlington, G. J. Participation of the transcription factor C/EBP delta in the acute-phase regulation of the human gene for complement component C3. Proc. Natl. Acad. Sci. USA 90(7):2584-2588; 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , Issue.7 , pp. 2584-2588
    • Juan, T.S.1    Wilson, D.R.2    Wilde, M.D.3    Darlington, G.J.4
  • 33
    • 0033580985 scopus 로고    scopus 로고
    • Initiation of mammalian liver development from endoderm by fibroblast growth factors
    • Jung, J.; Zheng, M.; Goldfarb, M.; Zaret, K. S. Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science 284(5422):1998-2003; 1999.
    • (1999) Science , vol.284 , Issue.5422 , pp. 1998-2003
    • Jung, J.1    Zheng, M.2    Goldfarb, M.3    Zaret, K.S.4
  • 34
    • 32844471999 scopus 로고    scopus 로고
    • Identification and differentiation of hepatic stem cells during liver development
    • Kamiya, A.; Gonzalez, F. J.; Nakauchi, H. Identification and differentiation of hepatic stem cells during liver development. Front. Biosci. 11:1302-1310; 2006.
    • (2006) Front. Biosci , vol.11 , pp. 1302-1310
    • Kamiya, A.1    Gonzalez, F.J.2    Nakauchi, H.3
  • 37
    • 33745437684 scopus 로고    scopus 로고
    • Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue
    • Kern, S.; Eichler, H.; Stoeve, J.; Kluter, H.; Bieback, K. Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 24(5):1294-1301; 2006.
    • (2006) Stem Cells , vol.24 , Issue.5 , pp. 1294-1301
    • Kern, S.1    Eichler, H.2    Stoeve, J.3    Kluter, H.4    Bieback, K.5
  • 38
    • 0037064554 scopus 로고    scopus 로고
    • Cytokine regulation of liver development
    • Kinoshita, T.; Miyajima, A. Cytokine regulation of liver development. Biochim. Biophys. Acta 1592(3):303-312; 2002.
    • (2002) Biochim. Biophys. Acta , vol.1592 , Issue.3 , pp. 303-312
    • Kinoshita, T.1    Miyajima, A.2
  • 39
    • 33646122663 scopus 로고    scopus 로고
    • The expression of mesenchymal, neural and haematopoietic stem cell markers in adult hepatocytes proliferating in vitro
    • Koenig, S.; Krause, P.; Drabent, B.; Schaeffner, I.; Christ, B.; Schwartz, P.; Unthan-Fechner, K.; Probst, I. The expression of mesenchymal, neural and haematopoietic stem cell markers in adult hepatocytes proliferating in vitro. J. Hepatol. 44(6):1115-1124; 2006.
    • (2006) J. Hepatol , vol.44 , Issue.6 , pp. 1115-1124
    • Koenig, S.1    Krause, P.2    Drabent, B.3    Schaeffner, I.4    Christ, B.5    Schwartz, P.6    Unthan-Fechner, K.7    Probst, I.8
  • 40
    • 2942536704 scopus 로고    scopus 로고
    • Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein
    • Kowanetz, M.; Valcourt, U.; Bergstrom, R.; Heldin, C. H.; Moustakas, A. Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. Mol. Cell. Biol. 24(10):4241-4254; 2004.
    • (2004) Mol. Cell. Biol , vol.24 , Issue.10 , pp. 4241-4254
    • Kowanetz, M.1    Valcourt, U.2    Bergstrom, R.3    Heldin, C.H.4    Moustakas, A.5
  • 41
    • 33747370376 scopus 로고    scopus 로고
    • Plasticity and expanding complexity of the hepatic transcription factor network during liver development
    • Kyrmizi, I.; Hatzis, P.; Katrakili, N.; Tronche, F.; Gonzalez, F. J.; Talianidis, I. Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 20(16):2293-2305; 2006.
    • (2006) Genes Dev , vol.20 , Issue.16 , pp. 2293-2305
    • Kyrmizi, I.1    Hatzis, P.2    Katrakili, N.3    Tronche, F.4    Gonzalez, F.J.5    Talianidis, I.6
  • 42
    • 38849153472 scopus 로고    scopus 로고
    • Strategies to in vitro assessment of major human CYP enzyme activities by using liquid chromatography tandem mass spectrometry
    • Lahoz, A.; Donato, M. T.; Castell, J. V.; Gómez-Lechón, M. J. Strategies to in vitro assessment of major human CYP enzyme activities by using liquid chromatography tandem mass spectrometry. Curr. Drug Metab. 9(1):12-19; 2008.
    • (2008) Curr. Drug Metab , vol.9 , Issue.1 , pp. 12-19
    • Lahoz, A.1    Donato, M.T.2    Castell, J.V.3    Gómez-Lechón, M.J.4
  • 43
    • 35649018168 scopus 로고    scopus 로고
    • Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry
    • Lahoz, A.; Donato, M. T.; Picazo, L.; Gómez-Lechón, M. J.; Castell, J. V. Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry. Toxicol. In Vitro 21(7):1247-1252; 2007.
    • (2007) Toxicol. In Vitro , vol.21 , Issue.7 , pp. 1247-1252
    • Lahoz, A.1    Donato, M.T.2    Picazo, L.3    Gómez-Lechón, M.J.4    Castell, J.V.5
  • 45
    • 4444269045 scopus 로고    scopus 로고
    • Characterization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue
    • Lee, R. H.; Kim, B.; Choi, I.; Kim, H.; Choi, H. S.; Suh, K.; Bae, Y. C.; Jung, J. S. Characterization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue. Cell. Physiol. Biochem. 14(4-6):311-324; 2004.
    • (2004) Cell. Physiol. Biochem , vol.14 , Issue.4-6 , pp. 311-324
    • Lee, R.H.1    Kim, B.2    Choi, I.3    Kim, H.4    Choi, H.S.5    Suh, K.6    Bae, Y.C.7    Jung, J.S.8
  • 46
    • 0034090310 scopus 로고    scopus 로고
    • Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
    • Li, J.; Ning, G.; Duncan, S. A. Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev. 14(4):464-474; 2000.
    • (2000) Genes Dev , vol.14 , Issue.4 , pp. 464-474
    • Li, J.1    Ning, G.2    Duncan, S.A.3
  • 47
    • 40149086838 scopus 로고    scopus 로고
    • Stem cells for liver tissue repair: Current knowledge and perspectives
    • Lysy, P. A.; Campard, D.; Smets, F.; Najimi, M.; Sokal, E. M. Stem cells for liver tissue repair: Current knowledge and perspectives. World J. Gastroenterol. 14(6): 864-875; 2008.
    • (2008) World J. Gastroenterol , vol.14 , Issue.6 , pp. 864-875
    • Lysy, P.A.1    Campard, D.2    Smets, F.3    Najimi, M.4    Sokal, E.M.5
  • 48
    • 0024506160 scopus 로고
    • The role of cis-acting promoter elements in tissue-specific albumin gene expression
    • Maire, P.; Wuarin, J.; Schibler, U. The role of cis-acting promoter elements in tissue-specific albumin gene expression. Science 244(4902):343-346; 1989.
    • (1989) Science , vol.244 , Issue.4902 , pp. 343-346
    • Maire, P.1    Wuarin, J.2    Schibler, U.3
  • 49
    • 33749551429 scopus 로고    scopus 로고
    • Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4alpha function and promote dedifferentiation in human hepatoma cells
    • Martinez-Jimenéz, C. P.; Gómez-Lechón, M. J.; Castell, J. V.; Jover, R. Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4alpha function and promote dedifferentiation in human hepatoma cells. J. Biol. Chem. 281(40):29840-29849; 2006.
    • (2006) J. Biol. Chem , vol.281 , Issue.40 , pp. 29840-29849
    • Martinez-Jimenéz, C.P.1    Gómez-Lechón, M.J.2    Castell, J.V.3    Jover, R.4
  • 51
    • 0038045136 scopus 로고    scopus 로고
    • Michalopoulos, G. K.; Bowen, W. C.; Mule, K.; Luo, J. HGF-, EGF-, and dexamethasone-induced gene expression patterns during formation of tissue in hepatic organoid cultures. Gene Expr. 11(2):55-75; 2003.
    • Michalopoulos, G. K.; Bowen, W. C.; Mule, K.; Luo, J. HGF-, EGF-, and dexamethasone-induced gene expression patterns during formation of tissue in hepatic organoid cultures. Gene Expr. 11(2):55-75; 2003.
  • 52
    • 0026634172 scopus 로고
    • A ubiquitous factor is required for C/EBP-related proteins to form stable transcription complexes on an albumin promoter segment in vitro
    • Milos, P. M.; Zaret, K. S. A ubiquitous factor is required for C/EBP-related proteins to form stable transcription complexes on an albumin promoter segment in vitro. Genes Dev. 6(6):991-1004; 1992.
    • (1992) Genes Dev , vol.6 , Issue.6 , pp. 991-1004
    • Milos, P.M.1    Zaret, K.S.2
  • 53
    • 0036412191 scopus 로고    scopus 로고
    • DNA binding activity of C/EBPbeta and C/EBPdelta for the rat alpha2-macroglobulin gene promoter is regulated in an acute-phase dependent manner
    • Milosavljevic, T. S.; Petrovic, M. V.; Cvetkovic, I. D.; Grigorov, I. I. DNA binding activity of C/EBPbeta and C/EBPdelta for the rat alpha2-macroglobulin gene promoter is regulated in an acute-phase dependent manner. Biochemistry (Mosc) 67(8):918-926; 2002.
    • (2002) Biochemistry (Mosc) , vol.67 , Issue.8 , pp. 918-926
    • Milosavljevic, T.S.1    Petrovic, M.V.2    Cvetkovic, I.D.3    Grigorov, I.I.4
  • 55
    • 3242695063 scopus 로고    scopus 로고
    • Improvement of postnatal neovascularization by human adipose tissue-derived stem cells
    • Miranville, A.; Heeschen, C.; Sengenes, C.; Curat, C. A.; Busse, R.; Bouloumie, A. Improvement of postnatal neovascularization by human adipose tissue-derived stem cells. Circulation 110(3):349-355; 2004.
    • (2004) Circulation , vol.110 , Issue.3 , pp. 349-355
    • Miranville, A.1    Heeschen, C.2    Sengenes, C.3    Curat, C.A.4    Busse, R.5    Bouloumie, A.6
  • 57
    • 0032533241 scopus 로고    scopus 로고
    • GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo
    • Morrisey, E. E.; Tang, Z.; Sigrist, K.; Lu, M. M.; Jiang, F.; Ip, H. S.; Parmacek, M. S. GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev. 12(22):3579-3590; 1998.
    • (1998) Genes Dev , vol.12 , Issue.22 , pp. 3579-3590
    • Morrisey, E.E.1    Tang, Z.2    Sigrist, K.3    Lu, M.M.4    Jiang, F.5    Ip, H.S.6    Parmacek, M.S.7
  • 58
    • 23644440056 scopus 로고    scopus 로고
    • Comparison of mesenchymal stem cells obtained from different human tissues
    • Musina, R. A.; Bekchanova, E. S.; Sukhikh, G. T. Comparison of mesenchymal stem cells obtained from different human tissues. Bull. Exp. Biol. Med. 139(4):504-509; 2005.
    • (2005) Bull. Exp. Biol. Med , vol.139 , Issue.4 , pp. 504-509
    • Musina, R.A.1    Bekchanova, E.S.2    Sukhikh, G.T.3
  • 59
    • 33746805922 scopus 로고    scopus 로고
    • Id3 is important for proliferation and differentiation of the hepatoblasts during the chick liver development
    • Nakayama, M.; Matsumoto, K.; Tatsumi, N.; Yanai, M.; Yokouchi, Y. Id3 is important for proliferation and differentiation of the hepatoblasts during the chick liver development. Mech. Dev. 123(7):580-590; 2006.
    • (2006) Mech. Dev , vol.123 , Issue.7 , pp. 580-590
    • Nakayama, M.1    Matsumoto, K.2    Tatsumi, N.3    Yanai, M.4    Yokouchi, Y.5
  • 61
    • 33646040153 scopus 로고    scopus 로고
    • Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture
    • Ong, S. Y.; Dai, H.; Leong, K. W. Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture. Biomaterials 27(22):4087-4097; 2006.
    • (2006) Biomaterials , vol.27 , Issue.22 , pp. 4087-4097
    • Ong, S.Y.1    Dai, H.2    Leong, K.W.3
  • 63
    • 39749185584 scopus 로고    scopus 로고
    • The use of mesenchymal stem cells for chondrogenesis
    • Pelttari, K.; Steck, E.; Richter, W. The use of mesenchymal stem cells for chondrogenesis. Injury 39(Suppl. 1): S58-65; 2008.
    • (2008) Injury , vol.39 , Issue.SUPPL. 1
    • Pelttari, K.1    Steck, E.2    Richter, W.3
  • 64
    • 0242266956 scopus 로고    scopus 로고
    • Semi-automatic quantitative RT-PCR to measure CYP induction by drugs in human hepatocytes
    • Perez, G.; Tabares, B.; Jover, R.; Gómez-Lechón, M. J.; Castell, J. V. Semi-automatic quantitative RT-PCR to measure CYP induction by drugs in human hepatocytes. Toxicol. In Vitro 17(5-6):643-649; 2003.
    • (2003) Toxicol. In Vitro , vol.17 , Issue.5-6 , pp. 643-649
    • Perez, G.1    Tabares, B.2    Jover, R.3    Gómez-Lechón, M.J.4    Castell, J.V.5
  • 65
    • 0031938718 scopus 로고    scopus 로고
    • Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat
    • Petersen, B. E.; Goff, J. P.; Greenberger, J. S.; Michalopoulos, G. K. Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat. Hepatology 27(2): 433-445; 1998.
    • (1998) Hepatology , vol.27 , Issue.2 , pp. 433-445
    • Petersen, B.E.1    Goff, J.P.2    Greenberger, J.S.3    Michalopoulos, G.K.4
  • 66
    • 36249021493 scopus 로고    scopus 로고
    • Concise review: Mesenchymal stem/multipotent stromal cells: the state of trans-differentiation and modes of tissue repair-current views
    • Phinney, D. G.; Prockop, D. J. Concise review: mesenchymal stem/multipotent stromal cells: the state of trans-differentiation and modes of tissue repair-current views. Stem Cells 25(11):2896-2902; 2007.
    • (2007) Stem Cells , vol.25 , Issue.11 , pp. 2896-2902
    • Phinney, D.G.1    Prockop, D.J.2
  • 67
    • 3142663241 scopus 로고    scopus 로고
    • Mesenchymal stem cells and their potential as cardiac therapeutics
    • Pittenger, M. F.; Martin, B. J. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res. 95(1):9-20; 2004.
    • (2004) Circ. Res , vol.95 , Issue.1 , pp. 9-20
    • Pittenger, M.F.1    Martin, B.J.2
  • 70
    • 0041735332 scopus 로고    scopus 로고
    • Quantitative RT-PCR measurement of human cytochrome P-450s: Application to drug induction studies
    • Rodriguez-Antona, C. J. R.; Gómez-Lechón, M. J.; Castell, J. V. Quantitative RT-PCR measurement of human cytochrome P-450s: Application to drug induction studies. Arch. Biochem. Biophys. 376:109-116; 2000.
    • (2000) Arch. Biochem. Biophys , vol.376 , pp. 109-116
    • Rodriguez-Antona, C.J.R.1    Gómez-Lechón, M.J.2    Castell, J.V.3
  • 71
    • 27644457450 scopus 로고    scopus 로고
    • Mesenchymal stem cells from human bone marrow and adipose tissue: Isolation, characterization, and differentiation potentialities
    • Romanov, Y. A.; Darevskaya, A. N.; Merzlikina, N. V.; Buravkova, L. B. Mesenchymal stem cells from human bone marrow and adipose tissue: Isolation, characterization, and differentiation potentialities. Bull. Exp. Biol. Med. 140(1):138-143; 2005.
    • (2005) Bull. Exp. Biol. Med , vol.140 , Issue.1 , pp. 138-143
    • Romanov, Y.A.1    Darevskaya, A.N.2    Merzlikina, N.V.3    Buravkova, L.B.4
  • 73
    • 23644456193 scopus 로고    scopus 로고
    • Comparison of human stem cells derived from various mesenchymal tissues: Superiority of synovium as a cell source
    • Sakaguchi, Y.; Sekiya, I.; Yagishita, K.; Muneta, T. Comparison of human stem cells derived from various mesenchymal tissues: Superiority of synovium as a cell source. Arthritis Rheum. 52(8):2521-2529; 2005.
    • (2005) Arthritis Rheum , vol.52 , Issue.8 , pp. 2521-2529
    • Sakaguchi, Y.1    Sekiya, I.2    Yagishita, K.3    Muneta, T.4
  • 74
    • 0036392154 scopus 로고    scopus 로고
    • Enhanced in vitro maturation of fetal mouse liver cells with oncostatin M, nicotinamide, and dimethyl sulfoxide
    • Sakai, Y.; Jiang, J.; Kojima, N.; Kinoshita, T.; Miyajima, A. Enhanced in vitro maturation of fetal mouse liver cells with oncostatin M, nicotinamide, and dimethyl sulfoxide. Cell Transplant. 11(5):435-441; 2002.
    • (2002) Cell Transplant , vol.11 , Issue.5 , pp. 435-441
    • Sakai, Y.1    Jiang, J.2    Kojima, N.3    Kinoshita, T.4    Miyajima, A.5
  • 76
    • 12844269935 scopus 로고    scopus 로고
    • Differentiation of human adipose stromal cells into hepatic lineage in vitro and in vivo
    • Seo, M. J.; Suh, S. Y.; Bae, Y. C.; Jung, J. S. Differentiation of human adipose stromal cells into hepatic lineage in vitro and in vivo. Biochem. Biophys. Res. Commun. 328(1):258-264; 2005.
    • (2005) Biochem. Biophys. Res. Commun , vol.328 , Issue.1 , pp. 258-264
    • Seo, M.J.1    Suh, S.Y.2    Bae, Y.C.3    Jung, J.S.4
  • 77
    • 13444310931 scopus 로고    scopus 로고
    • Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung
    • Serls, A. E.; Doherty, S.; Parvatiyar, P.; Wells, J. M.; Deutsch, G. H. Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung. Development 132(1):35-47; 2005.
    • (2005) Development , vol.132 , Issue.1 , pp. 35-47
    • Serls, A.E.1    Doherty, S.2    Parvatiyar, P.3    Wells, J.M.4    Deutsch, G.H.5
  • 78
    • 34547281072 scopus 로고    scopus 로고
    • Hepatocyte differentiation of mesenchymal stem cells from rat peritoneal adipose tissue in vitro and in vivo
    • Sgodda, M.; Aurich, H.; Kleist, S.; Aurich, I.; Konig, S.; Dollinger, M. M.; Fleig, W. E.; Christ, B. Hepatocyte differentiation of mesenchymal stem cells from rat peritoneal adipose tissue in vitro and in vivo. Exp. Cell Res. 313(13):2875-2886; 2007.
    • (2007) Exp. Cell Res , vol.313 , Issue.13 , pp. 2875-2886
    • Sgodda, M.1    Aurich, H.2    Kleist, S.3    Aurich, I.4    Konig, S.5    Dollinger, M.M.6    Fleig, W.E.7    Christ, B.8
  • 79
    • 48949120846 scopus 로고    scopus 로고
    • Differentiation of mouse and human embryonic stem cells into hepatic lineages
    • Shiraki, N.; Umeda, K.; Sakashita, N.; Takeya, M.; Kume, K.; Kume, S. Differentiation of mouse and human embryonic stem cells into hepatic lineages. Genes Cells 13(7):731-746; 2008.
    • (2008) Genes Cells , vol.13 , Issue.7 , pp. 731-746
    • Shiraki, N.1    Umeda, K.2    Sakashita, N.3    Takeya, M.4    Kume, K.5    Kume, S.6
  • 80
    • 33751401356 scopus 로고    scopus 로고
    • Sequential exposure to cytokines reflecting embryogenesis: The key for in vitro differentiation of adult bone marrow stem cells into functional hepatocyte-like cells
    • Snykers, S.; Vanhaecke, T.; Papeleu, P.; Luttun, A.; Jiang, Y.; Vander Heyden, Y.; Verfaillie, C.; Rogiers, V. Sequential exposure to cytokines reflecting embryogenesis: the key for in vitro differentiation of adult bone marrow stem cells into functional hepatocyte-like cells. Toxicol. Sci. 94(2):330-341; 2006.
    • (2006) Toxicol. Sci , vol.94 , Issue.2 , pp. 330-341
    • Snykers, S.1    Vanhaecke, T.2    Papeleu, P.3    Luttun, A.4    Jiang, Y.5    Vander Heyden, Y.6    Verfaillie, C.7    Rogiers, V.8
  • 81
    • 4944257952 scopus 로고    scopus 로고
    • Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow
    • Song, L.; Tuan, R. S. Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow. FASEB J. 18(9):980-982; 2004.
    • (2004) FASEB J , vol.18 , Issue.9 , pp. 980-982
    • Song, L.1    Tuan, R.S.2
  • 82
    • 0032559647 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells
    • Spath, G. F.; Weiss, M. C. Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells. J. Cell. Biol. 140(4):935-946; 1998.
    • (1998) J. Cell. Biol , vol.140 , Issue.4 , pp. 935-946
    • Spath, G.F.1    Weiss, M.C.2
  • 83
    • 33846083134 scopus 로고    scopus 로고
    • Transcriptional control in the mammalian liver: Liver development, perinatal repression, and zonal gene regulation
    • Spear, B. T.; Jin, L.; Ramasamy, S.; Dobierzewska, A. Transcriptional control in the mammalian liver: liver development, perinatal repression, and zonal gene regulation. Cell. Mol. Life Sci. 63(24):2922-2938; 2006.
    • (2006) Cell. Mol. Life Sci , vol.63 , Issue.24 , pp. 2922-2938
    • Spear, B.T.1    Jin, L.2    Ramasamy, S.3    Dobierzewska, A.4
  • 84
    • 0344541909 scopus 로고    scopus 로고
    • Analysis of the mouse selenoprotein P gene
    • Steinert, P.; Bachner, D.; Flohe, L. Analysis of the mouse selenoprotein P gene. Biol. Chem. 379(6):683-691; 1998.
    • (1998) Biol. Chem , vol.379 , Issue.6 , pp. 683-691
    • Steinert, P.1    Bachner, D.2    Flohe, L.3
  • 86
    • 0037672369 scopus 로고    scopus 로고
    • Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells
    • Suzuki, A.; Iwama, A.; Miyashita, H.; Nakauchi, H.; Taniguchi, H. Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells. Development 130(11):2513-2524; 2003.
    • (2003) Development , vol.130 , Issue.11 , pp. 2513-2524
    • Suzuki, A.1    Iwama, A.2    Miyashita, H.3    Nakauchi, H.4    Taniguchi, H.5
  • 87
    • 33750121487 scopus 로고    scopus 로고
    • Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells
    • Talens-Visconti, R.; Bonora, A.; Jover, R.; Mirabet, V.; Carbonell, F.; Castell, J. V.; Gómez-Lechón, M. J. Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells. World J. Gastroenterol. 12(36): 5834-5845; 2006.
    • (2006) World J. Gastroenterol , vol.12 , Issue.36 , pp. 5834-5845
    • Talens-Visconti, R.1    Bonora, A.2    Jover, R.3    Mirabet, V.4    Carbonell, F.5    Castell, J.V.6    Gómez-Lechón, M.J.7
  • 89
    • 0026031601 scopus 로고
    • CCAAT-enhancer binding protein: A component of a differentiation switch
    • Umek, R. M.; Friedman, A. D.; McKnight, S. L. CCAAT-enhancer binding protein: A component of a differentiation switch. Science 251(4991):288-292; 1991.
    • (1991) Science , vol.251 , Issue.4991 , pp. 288-292
    • Umek, R.M.1    Friedman, A.D.2    McKnight, S.L.3
  • 90
    • 0032512722 scopus 로고    scopus 로고
    • A short proximal promoter and the distal hepatic control region-1 (HCR-1) contribute to the liver specificity of the human apolipoprotein C-II gene. Hepatic enhancement by HCR-1 requires two proximal hormone response elements which have different binding specificities for orphan receptors HNF-4, ARP-1, and EAR-2
    • Vorgia, P.; Zannis, V. I.; Kardassis, D. A short proximal promoter and the distal hepatic control region-1 (HCR-1) contribute to the liver specificity of the human apolipoprotein C-II gene. Hepatic enhancement by HCR-1 requires two proximal hormone response elements which have different binding specificities for orphan receptors HNF-4, ARP-1, and EAR-2. J. Biol. Chem. 273(7): 4188-4196; 1998.
    • (1998) J. Biol. Chem , vol.273 , Issue.7 , pp. 4188-4196
    • Vorgia, P.1    Zannis, V.I.2    Kardassis, D.3
  • 91
    • 3042841932 scopus 로고    scopus 로고
    • Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction
    • Wang, P. P.; Wang, J. H.; Yan, Z. P.; Hu, M. Y.; Lau, G. K.; Fan, S. T.; Luk, J. M. Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction. Biochem. Biophys. Res. Commun. 320(3): 712-716; 2004.
    • (2004) Biochem. Biophys. Res. Commun , vol.320 , Issue.3 , pp. 712-716
    • Wang, P.P.1    Wang, J.H.2    Yan, Z.P.3    Hu, M.Y.4    Lau, G.K.5    Fan, S.T.6    Luk, J.M.7
  • 92
    • 0034951680 scopus 로고    scopus 로고
    • Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development
    • Weinstein, M.; Monga, S. P.; Liu, Y.; Brodie, S. G.; Tang, Y.; Li, C.; Mishra, L.; Deng, C. X. Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development. Mol. Cell. Biol. 21(15):5122-5131; 2001.
    • (2001) Mol. Cell. Biol , vol.21 , Issue.15 , pp. 5122-5131
    • Weinstein, M.1    Monga, S.P.2    Liu, Y.3    Brodie, S.G.4    Tang, Y.5    Li, C.6    Mishra, L.7    Deng, C.X.8
  • 93
    • 33749642368 scopus 로고    scopus 로고
    • C/EBPalpha and C/EBPbeta are markers of early liver development
    • Westmacott, A.; Burke, Z. D.; Oliver, G.; Slack, J. M.; Tosh, D. C/EBPalpha and C/EBPbeta are markers of early liver development. Int. J. Dev. Biol. 50(7):653-657; 2006.
    • (2006) Int. J. Dev. Biol , vol.50 , Issue.7 , pp. 653-657
    • Westmacott, A.1    Burke, Z.D.2    Oliver, G.3    Slack, J.M.4    Tosh, D.5
  • 94
    • 40349085915 scopus 로고    scopus 로고
    • A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells
    • Yamamoto, Y.; Banas, A.; Murata, S.; Ishikawa, M.; Lim, C. R.; Teratani, T.; Hatada, I.; Matsubara, K.; Kato, T.; Ochiya, T. A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells. FEBS J. 275(6): 1260-1273; 2008.
    • (2008) FEBS J , vol.275 , Issue.6 , pp. 1260-1273
    • Yamamoto, Y.1    Banas, A.2    Murata, S.3    Ishikawa, M.4    Lim, C.R.5    Teratani, T.6    Hatada, I.7    Matsubara, K.8    Kato, T.9    Ochiya, T.10
  • 95
    • 0030579115 scopus 로고    scopus 로고
    • Structure and organization of the gene encoding human selenoprotein
    • Yasui, Y.; Hasada, K.; Yang, J. G.; Koiwai, O. Structure and organization of the gene encoding human selenoprotein. Gene 175(1-2):269-270; 1996.
    • (1996) Gene , vol.175 , Issue.1-2 , pp. 269-270
    • Yasui, Y.1    Hasada, K.2    Yang, J.G.3    Koiwai, O.4
  • 97
    • 4344710622 scopus 로고    scopus 로고
    • The developmental regulation of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression in the liver is partially dissociated from the control of gluconeogenesis and lipid catabolism
    • Yubero, P.; Hondares, E.; Carmona, M. C.; Rossell, M.; Gonzalez, F. J.; Iglesias, R.; Giralt, M.; Villarroya, F. The developmental regulation of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression in the liver is partially dissociated from the control of gluconeogenesis and lipid catabolism. Endocrinology 145(9):4268-4277; 2004.
    • (2004) Endocrinology , vol.145 , Issue.9 , pp. 4268-4277
    • Yubero, P.1    Hondares, E.2    Carmona, M.C.3    Rossell, M.4    Gonzalez, F.J.5    Iglesias, R.6    Giralt, M.7    Villarroya, F.8
  • 98
    • 1942422206 scopus 로고    scopus 로고
    • Regulation of Hex gene expression and initial stages of avian hepatogenesis by Bmp and Fgf signaling
    • Zhang, W.; Yatskievych, T. A.; Baker, R. K.; Antin, P. B. Regulation of Hex gene expression and initial stages of avian hepatogenesis by Bmp and Fgf signaling. Dev. Biol. 268(2):312-326; 2004.
    • (2004) Dev. Biol , vol.268 , Issue.2 , pp. 312-326
    • Zhang, W.1    Yatskievych, T.A.2    Baker, R.K.3    Antin, P.B.4
  • 99
    • 15044362819 scopus 로고    scopus 로고
    • GATA6 is essential for embryonic development of the liver but dispensable for early heart formation
    • Zhao, R.; Watt, J. A.; Li, J.; Luebke-Wheeler, J.; Morrisey, E. E.; Duncan, S. A. GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol. Cell. Biol. 25(7):2622-2631; 2005.
    • (2005) Mol. Cell. Biol , vol.25 , Issue.7 , pp. 2622-2631
    • Zhao, R.1    Watt, J.A.2    Li, J.3    Luebke-Wheeler, J.4    Morrisey, E.E.5    Duncan, S.A.6
  • 100
    • 35148858697 scopus 로고    scopus 로고
    • Transcriptional activation of hepatic ACSL3 and ACSL5 by oncostatin m reduces hypertriglyceridemia through enhanced beta-oxidation
    • Zhou, Y.; Abidi, P.; Kim, A.; Chen, W.; Huang, T. T.; Kraemer, F. B.; Liu, J. Transcriptional activation of hepatic ACSL3 and ACSL5 by oncostatin m reduces hypertriglyceridemia through enhanced beta-oxidation. Arterioscler. Thromb. Vasc. Biol. 27(10):2198-2205; 2007.
    • (2007) Arterioscler. Thromb. Vasc. Biol , vol.27 , Issue.10 , pp. 2198-2205
    • Zhou, Y.1    Abidi, P.2    Kim, A.3    Chen, W.4    Huang, T.T.5    Kraemer, F.B.6    Liu, J.7


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