A short proximal promoter and the distal hepatic control region-1 (HCR- 1) contribute to the liver specificity of the human apolipoprotein C-II gene. Hepatic enhancement by HCR-1 requires two proximal hormone response elements which have different binding specificities for orphan receptors HNF-4, ARP- 1, and EAR-2

Journal of Biological Chemistry

Volumn 273, Issue 7, 1998, Pages 4188-4196

  Vorgia, Pelagia ^a   Zannis, Vassilis I ^a   Kardassis, Dimitris ^a  

^a UNIVERSITY OF CRETE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN C2; CELL NUCLEUS RECEPTOR; CHLORAMPHENICOL ACETYLTRANSFERASE; DEOXYRIBONUCLEASE I; NUCLEAR FACTOR;

ANIMAL CELL; ARTICLE; CELL STRAIN CACO 2; CELL STRAIN HEPG2; CONTROLLED STUDY; ENHANCER REGION; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION REGULATION; GENE MUTATION; HELA CELL; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; LIVER; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR BINDING; TISSUE SPECIFICITY; TRANSACTIVATION;

ANIMALS; APOLIPOPROTEIN C-II; APOLIPOPROTEINS C; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELLS, CULTURED; DNA FOOTPRINTING; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; LIVER; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); RATS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0032512722     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.7.4188     Document Type: Article

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