Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage

Biochemical and Biophysical Research Communications

Volumn 276, Issue 3, 2000, Pages 1155-1161

  Keng, Vincent W ^a,b   Yagi, Hideshi ^b   Ikawa, Masahito ^c   Nagano, Takashi ^b   Myint, Zaw ^b   Yamada, Kazuya ^b   Tanaka, Takashi ^b   Sato, Ayuko ^a   Muramatsu, Ikunobu ^b   Okabe, Masaru ^c   Sato, Makoto ^b,d   Noguchi, Tamio ^a,b  

^a NAGOYA UNIVERSITY   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Gene targeting; Hematopoiesis; Hepatic endoderm differentiation; Hepatocyte differentiation; Hex

Indexed keywords

ALBUMIN; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; EMBRYO; GENE TARGETING; HEMATOPOIESIS; HETEROZYGOSITY; HOMEOBOX; LIVER CELL; LIVER DEVELOPMENT; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

EID: 0034609960     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3548     Document Type: Article

References (37)

1. Molecular genetics of early liver development
2. Initiation of mammalian liver development from endoderm by fibroblast growth factors
3. Hepatic specification of the gut endoderm in vitro: Cell signaling and transcriptional control
4. Differentiation of the mouse hepatic primordium. I. An analysis of tissue interactions in hepatocyte differentiation
5. Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells
6. PCR cloning of an orphan homeobox gene (PRH) preferentially expressed in myeloid and liver cells
7. The XHex homeobox gene is expressed during development of the vascular endothelium: Overexpression leads to an increase in vascular endothelial cell number
8. Expression of the homeobox gene Hex during early stages of chick embryo development
9. A role for the extraembryonic yolk syncytial layer in patterning the zebrafish embryo suggested by properties of the hex gene
10. cDNA cloning and expression of rat homeobox gene, Hex, and functional characterization of the protein
11. HEX: A novel homeobox gene expressed during haematopoiesis and conserved between mouse and human
12. Expression of Hex mRNA in early murine postimplantation embryo development
13. Hex: A homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors
14. Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo
15. Differential expression of a novel proline-rich homeobox gene (Prh) in human hematolymphopoietic cells
16. Genomic organization and promoter analysis of a mouse homeobox gene, Hex
17. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
18. Identification of a novel adenylate kinase system in the brain: Cloning of the fourth adenylate kinase
19. Liver-enriched transcription factors and hepatocyte differentiation
20. The cuthomeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3β in the developing murine liver and pancreas
21. Regulation of a transcription factor network required for differentiation and metabolism
22. Mesoderm-specific expression of the divergent homeobox gene Hlx during murine embryogenesis
23. Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function
24. Expression and function of the homeodomain-containing protein hex in thyroid cells
25. The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1
26. The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene
27. Definitive hematopoiesis is autonomously initiated by the AGM region
28. c-jun is essential for normal mouse development and hepatogenesis
29. Scatter factor/hepatocyte growth factor is essential for liver development
30. Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4
31. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
32. The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation
33. Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region
34. An 'in-out' strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: Analysis of the beta-globin locus control region
35. A novel NK-related mouse homeobox gene: Expression in central and peripheral nervous structures during embryonic development
36. Know your neighbors: Three phenotypes in null mutants of the myogenic bHLH gene MRF4
37. Long-range disruption of gene expression by a selectable marker cassette