Nitric oxide photogeneration from trans-Cr(cyclam)(ONO)2 + in a reducing environment. Activation of soluble guanylyl cyclase and arterial vasorelaxation

Journal of Medicinal Chemistry

Volumn 53, Issue 2, 2010, Pages 715-722

  Ostrowski, Alexis D ^a   Deakin, Sherine J ^b   Azhar, Bilal ^b   Miller, Thomas W ^c,d   Franco, Nestor ^c   Cherney, Melisa M ^e   Lee, Andrea J ^e   Burstyn, Judith N ^e   Fukuto, Jon M ^d,f   Megson, Ian L ^b   Ford, Peter C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF THE HIGHLANDS AND ISLANDS   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

^f SONOMA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ANTIOXIDANT; CHROMIUM DERIVATIVE; CHROMIUM DINITRITO COMPLEX; CYCLIC GMP; GLUTATHIONE; GUANOSINE TRIPHOSPHATE; GUANYLATE CYCLASE; GUANYLATE CYCLASE ACTIVATOR; GUANYLATE CYCLASE INHIBITOR; NITRIC OXIDE; UNCLASSIFIED DRUG; VASOCONSTRICTOR AGENT;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; CHEMOLUMINESCENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; LIGHT; NONHUMAN; PHOTOCHEMISTRY; PHOTOLYSIS; SWINE; THERMOSTABILITY; VASCULAR RING; VASODILATATION; WESTERN BLOTTING;

ANIMALS; ARTERIES; CHROMIUM; GUANYLATE CYCLASE; HETEROCYCLIC COMPOUNDS; NITRIC OXIDE; NITRIC OXIDE DONORS; OXIDATION-REDUCTION; PHOTOCHEMICAL PROCESSES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REDUCING AGENTS; SULFHYDRYL COMPOUNDS; SWINE; VASODILATION;

EID: 77249101344     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm9013357     Document Type: Article

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