Biological activity of designed photolabile metal nitrosyls: Light-dependent activation of soluble guanylate cyclase and vasorelaxant properties in rat aorta

Journal of Medicinal Chemistry

Volumn 49, Issue 25, 2006, Pages 7325-7330

  Madhani, Melanie ^a   Patra, Apurba K ^b   Miller, Thomas W ^c   Eroy Reveles, Aura A ^b   Hobbs, Adrian J ^a   Fukuto, Jon M ^d   Mascharak, Pradip K ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; GUANYLATE CYCLASE; NITRIC OXIDE; SOLUBLE GUANYLATE CYCLASE;

ANIMAL CELL; ANIMAL TISSUE; AORTA MEDIA; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; LIGHT EXPOSURE; NITROSYLATION; NONHUMAN; RAT; SMOOTH MUSCLE FIBER; ULTRAVIOLET RADIATION; VASODILATATION;

ANIMALS; AORTA; CELLS, CULTURED; CYCLIC GMP; ENZYME ACTIVATION; GUANYLATE CYCLASE; IRON; LIGHT; MANGANESE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NITRIC OXIDE DONORS; ORGANOMETALLIC COMPOUNDS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RUTHENIUM; STRUCTURE-ACTIVITY RELATIONSHIP; VASODILATION; VASODILATOR AGENTS;

EID: 33845483437     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0604629     Document Type: Article

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