Phagocytosis triggers macrophage release of Fas ligand and induces apoptosis of bystander leukocytes

Journal of Immunology

Volumn 162, Issue 1, 1999, Pages 480-485

  Brown, Simon B ^a,b   Savill, John ^a  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN;

APOPTOSIS; ARTICLE; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; NEUTROPHIL; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL;

ANTIGENS, CD95; APOPTOSIS; CELL DEATH; CELL-FREE SYSTEM; FAS LIGAND PROTEIN; HUMANS; JURKAT CELLS; LIGANDS; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MONOCYTES; NEUTROPHILS; OPSONIN PROTEINS; PHAGOCYTOSIS; ZYMOSAN;

EID: 0032964584     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Metchnikoff, E. 1893. Lectures on the Comparative Pathology of Inflammation. F. A. Starling and E. H. Starling, eds. and trans. Kegan, Paul, Trench, and Trubner, London.
2. Newman, S. L., J. E. Henson, and P. M. Henson. 1982. Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages. J. Exp. Med. 156:430.
3. Savill, J. S., A. H. Wyllie, J. E. Henson, M. J. Walport, P. M. Henson, and C. Haslett. 1989. Macrophage phagocytosis of aging neutrophils in inflammation: programmed cell death in the neutrophil leads to its recognition by macrophages. J. Clin. Invest. 83:865.
4. Grigg, J., J. Savill, C. Sarraf, C. Haslett, and M. Silverman. 1991. Neutrophil apoptosis and clearance from neonatal lungs. Lancet 338:720.
5. Savill, J. S., J. Smith, Y. Ren, C. Sarraf, F. Abbott, and A. J. Rees. 1992. Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis. Kidney Int. 42:924.
6. + T cells undergoing apoptosis: a mechanism for T cell clearance during resolution of viral infections. J. Exp. Med. 180: 1943.
7. Cox, G. J., J. Crossley, and Z. Xing. 1995. Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. Am. J. Respir. Cell. Mol. Biol. 12:232.
8. Tsuyuki, S., C. Bertrand, F. Erard, A. Trifilieff, J. Tsuyuki, M. Wesp, G. P. Anderson, and A. J. Coyle. 1995. Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways. J. Clin. Invest. 96:2924.
9. Woolley, K. L., P. G. Gibson, K. Carty, A. J. Wilson, S. H. Twaddell, and M. J. Woolley. 1996. Eosinophil apoptosis and the resolution of airway inflammation in asthma. Am. J. Respir. Crit. Care Med. 154:237.
10. 2 integrin CD11b/CD18 in neutrophil apoptosis: a homeostatic mechanism in inflammation. Immunity 5:653.
11. Milik, A. M., V. A. Buechner-Maxwell, J. Sonstein, S. Kim, G.D. Seitzman, T. F. Beals, and J. L. Curtis. 1997. Lung lymphocyte elimination by apoptosis in the murine response to intratracheal particulate antigen. J. Clin. Invest. 99:1082.
12. Kiener, P. A., P. M. Davis, G. C. Starling, C. Mehlin, S. J. Klebanoff, J. A. Ledbetter, and W. C. Liles. 1997. Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages. J. Exp. Med. 185:1511.
13. Kiener, P. A., P. M. Davis, B. M. Rankin, S. J. Klebanoff, J. A. Ledbetter, G. C. Starling, and W. C. Liles. 1997. Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation. J. Immunol. 159:1594.
14. Iwai, K., T. Miyawaki, T. Takizawa, A. Konno, K. Ohta, A. Yachie, H. Seki, and N. Taniguchi. 1994. Differential expression of bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes and neutrophils. Blood 84:1201.
15. Matsumoto, K., R. P. Schleimer, H. Saito, Y. Iikura, and B. S. Bochner. 1995. Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro. Blood 86:1437.
16. Liles, W. C., P. A. Kiener, J. A. Ledbetter, A. Aruffo, and S. J. Klebanoff. 1996. Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils. J. Exp. Med. 184:429.
17. Richardson, B. C., N. D. Lalwani, K. J. Johnson, and R. M. Marks. 1994. Fas ligation triggers apoptosis in macrophages but not endothelial cells. Eur. J. Immunol. 24:2640.
18. Druilhe, A., Z. Cai, S. Hailé, S. Chouaib, and M. Pretolani. 1996. Fas-mediated apoptosis in cultured human eosinophils. Blood 87:2822.
19. + T cells apoptosis. J. Immunol. 158:2456.
20. Mincheff, M., D. Loukinov, S. Zoubak, M. Hammett, and H. Meryman. 1998. Fas and Fas Ligand expression on human peripheral blood leukocytes. Vox Sang, 74:113.
21. Haslett, C., L. A. Guthrie, M. M. Kopaniak, R. B. Johnston, and P. M. Henson. 1985. Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide. Am. J. Pathol. 119:101.
22. Ren, Y., and J. Savill. 1995. Pro-inflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis. J. Immunol. 154:2366.
23. Musson, R. A. 1983. Human serum induces maturation of human monocytes in vitro. Am. J. Pathol. 111:331.
24. Homburg, C. E., M. de Haas, A. E. G. K. von dem Borne, A. J. Verhoeven, C. P. M. Reutelingsperger, and D. Roos. 1995. Human neutrophils lose their surface FcγRIII and acquire annexin V binding sites during apoptosis in vitro. Blood 85:532.
25. Brown, S. B., K. Bailey, and J. Savill. 1997. Actin is cleaved during constitutive apoptosis. Biochem. J. 323:233.
26. Dransfield, I., A.-M. Buckle, J. S. Savill, A. McDowall, C. Haslett, and N. Hogg. 1994. Neutrophil apoptosis is associated with a reduction in CD16 (FcγRIII) expression. J. Immunol. 153:1254.
27. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680.
28. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350.
29. Um, H.-D., J. M. Orenstein, and S. M. Wahl. 1996. Fas mediates apoptosis in human monocytes by a reactive oxygen intermediate dependent pathway. J. Immunol. 156:3469.
30. Mangan, D. F., G. R. Welch, and S. M. Wahl. 1991. Lipopolysaccharide, tumor necrosis factor-α and interleukin-1β prevent programmed cell death (apoptosis) in human peripheral blood monocytes. J. Immunol. 146:1541.
31. Whyte, M. K. B., L. C. Meagher, J. MacDermot, and C. Haslett. 1993. Impairment of function in aging neutrophils is associated with apoptosis. J. Immunol. 150:5124.
32. Savill, J., and C. Haslett. 1995. Granulocyte clearance by apoptosis in the resolution of inflammation. Semin. Cell. Biol. 6:385.
33. Voll, R. E., M. Herrmann, E. A. Roth, C. Stach, and J. R. Kalden. 1997. Immunosuppressive effects of apoptotic cells. Nature 390:350.
34. 2 and PAF. J. Clin. Invest. 101:890.
35. Tanaka, M., T. Itai, M. Adachi, and S. Nagata. 1998. Down-regulation of Fas ligand by shedding. Nat. Med. 4:31.
36. Smith, D., S. Sieg, and D. Kaplan. 1998. Aberrant detection of cell surface Fas Ligand with anti-peptide antibodies. J. Immunol. 160:4159.
37. Lee, A., M. K. B. Whyte, and C. Haslett. 1993. Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators. J. Leukocyte Biol. 54:283.