Alcohol influence on acrylamide to glycidamide metabolism assessed with hemoglobin-adducts and questionnaire data

Food and Chemical Toxicology

Volumn 48, Issue 3, 2010, Pages 820-824

  Vikström, Anna C ^a   Wilson, Kathryn M ^b   Paulsson, Birgit ^a   Athanassiadis, Ioannis ^a   Grönberg, Henrik ^c   Adami, Hans Olov ^b,c   Adolfsson, Jan ^c   Mucci, Lorelei A ^b,d   Bälter, Katarina ^c   Törnqvist, Margareta ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Acrylamide; Alcohol; Food frequency questionnaire; Glycidamide; Hemoglobin adducts

Indexed keywords

ACRYLAMIDE; ALCOHOL; CYTOCHROME P450 2E1; GLYCIDAMIDE;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BINDING COMPETITION; CONTROLLED STUDY; DIETARY INTAKE; ENZYME SUBSTRATE COMPLEX; FEMALE; HEMOGLOBIN ANALYSIS; HUMAN; LIVER METABOLISM; MALE; POPULATION BASED CASE CONTROL STUDY; PROSTATE CANCER; QUESTIONNAIRE; SMOKING; SPECIES COMPARISON;

ACRYLAMIDES; ADULT; ALCOHOL DRINKING; CASE-CONTROL STUDIES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; EPOXY COMPOUNDS; ETHANOL; FOOD HABITS; HEMOGLOBINS; HUMANS; MALE; PROSTATIC NEOPLASMS; QUESTIONNAIRES; SMOKING; SWEDEN;

EID: 76749141349     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.12.014     Document Type: Article

References (34)

1. Badger T.M., Ronis M.J.J., Lumpkin C.K., Valentine C.R., Shahare M., Irby D., Huang J., Mercado C., Thomas P., Ingelman-Sundberg M., and Crouch J. Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat. J. Pharmacol. Exp. Ther. 246 (1993) 438-447
2. Bergmark E. Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers, smokers, and nonsmokers. Chem. Res. Toxicol. 10 (1997) 78-84
3. Brantsaeter A.L., Haugen M., Mul A., Bjellaas T., Becher G., Claveren J.V., Alexander J., and Meltzer H.M. Exploration of different methods to assess dietary acrylamide exposure in pregnant women participating in the Norwegian Mother and Child Cohort Study (MoBa). Food Chem. Toxicol. 46 (2008) 2808-2814
4. Chang E.T., Hedelin M., Adami H.-O., Grönberg H., and Bälter K.A. Alcohol drinking and risk of localized versus advanced and sporadic versus familial prostate cancer in Sweden. Cancer Causes Control 16 (2005) 275-284
5. Doroshyenko O., Fuhr U., Kunz D., Frank D., Inzig M., Jetter A., Reith Y., Lazar A., Taubert D., Kirchheiner J., Baum M., Eisenbrand G., Berger F.I., Bertow D., Berkessel A., Sörgel F., Schömig E., and Tomalik-Scharte D. In vivo role of cytochrome P450 2E1 and glutathione-S-transferase activity for acrylamide toxicokinetics in humans. Cancer Epidemiol. Biomarkers Prev. 18 (2009) 433-443
6. Duale N., Bjellaas T., Alexander J., Becher G., Haugen M., Paulsen J.E., Frandsen H., Olesen P.T., and Brunborg G. Biomarkers of human exposure to acrylamide and relation to polymorphisms in metabolizing genes. Toxicol. Sci. 108 (2009) 90-99
7. Dybing E., Farmer P.B., Andersen M., Fennell T.R., Lalljie S.P.D., Müller D.J.G., Olin S., Petersen B.J., Schlatter J., Scholz G., Scimeca J.A., Slimani N., Törnqvist M., Tuijtelaars S., and Verger P. ILSI report: human exposure and internal dose assessments of acrylamide in food. Food Chem. Toxicol. 43 (2005) 365-410
8. Hagmar L., Wirfält E., Paulsson B., and Törnqvist M. Differences in hemoglobin adduct levels of acrylamide in the general population with respect to dietary intake, smoking habits and gender. Mutat. Res. 580 (2005) 157-165
9. Hedelin M., Klint A., Chang E.T., Bellocco R., Johansson J.-E., Andersson S.-O., Heinonen S.-M., Adami H.-O., Grönberg H., and Bälter K.A. Dietary phytoestrogen, serum enterolactone and risk of prostate cancer: the cancer prostate Sweden study (Sweden). Cancer Causes Control 17 (2006) 169-180
10. Hogervorst J.G., Schouten L.J., Konings E.J., Goldbohm R.A., and van den Brandt P.A. A prospective study of dietary acrylamide intake and the risk of endometrial, ovarian, and breast cancer. Cancer Epidemiol. Biomarkers Prev. 16 (2007) 2304-2313
11. IARC, 1994. International Agency for Research on Cancer (IARC), Acrylamide. In: Monographs on the Evaluation of Carcinogen Risk to Humans: Some Industrial Chemicals, No. 60, IARC, Lyon 1994, pp. 389-443.
12. Kütting B., Uter W., and Drexler H. The association between self-reported acrylamide intake and hemoglobin adducts as biomarkers of exposure. Cancer Causes Control 19 (2008) 273-281
13. Lieber C.S. Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998) - a review. Alcohol Clin. Exp. Res. 23 (1999) 991-1007
14. Mills C., Tlustos C., Evans R., and Matthews W. Dietary acrylamide exposure estimates for the United Kingdom and Ireland: comparison between semiprobabilistic and probabilistic exposure models. J. Agric. Food Chem. 56 (2009) 6039-6045
15. Mucci L.A., and Adami H.O. The plight of the potato: is dietary acrylamide a risk factor for human cancer. J. Natl. Cancer Inst. 101 (2009) 618-621
16. NTP-CERHR-Acrylamide-04. (National Toxicology Program, US Department of Health and Human Services - Center for the Evaluation of Risks to Human Reproduction). Expert Panel Report on the Reproductive and Developmental Toxicity of Acrylamide, June 2004.
17. Olesen P.T., Olsen A., Frandsen H., Frederiksen K., Overvad K., and Tjonneland A. Acrylamide exposure and incidence of breast cancer among postmenopausal women in the Danish diet, cancer and health study. Int. J. Cancer 122 (2008) 2094-2100
18. Oneta C.M., Lieber C.S., Li J., Rüttimann S., Schmid B., Lattmann J., Rosman A.S., and Seitz H.K. Dynamics of cytochrome P4502E1 activity in man: induction by ethanol and disappearance during withdrawal phase. J. Hepatol. 36 (2002) 47-52
19. Paulsson B., Athanassiadis I., Rydberg P., and Törnqvist M. Hemoglobin adducts from glycidamide: acetonization of hydrophilic groups for reproducible gas chromatography/tandem mass spectrometric analysis. Rapid Commun. Mass Spectrom. 17 (2003) 1859-1865
20. Paulsson B., Rannug A., Henderson A.P., Golding B.T., Törnqvist M., and Warholm M. In vitro studies of the influence of glutathione transferases and epoxide hydrolase on the detoxification of acrylamide and glycidamide in blood. Mutat. Res. 580 (2005) 53-59
21. Rice J.M. The carcinogenicity of acrylamide. Mutat. Res. 580 (2005) 3-20
22. Ronis M.J.J., Huang J., Crouch J., Mercado C., Irby D., Valentine C.R., Lumpkin C.K., Ingelman-Sundberg M., and Badger T.M. Cytochrome P450 CYP 2E1 induction during chronic alcohol exposure occurs by a two-step mechanism associated with blood alcohol concentrations in rats. J. Pharmacol. Exp. Ther. 264 (1992) 944-950
23. Schettgen T., Rossbach B., Kütting B., Letzel S., Drexler H., and Angerer J. Determination of haemoglobin adducts of acrylamide and glycidamide in smoking and non-smoking persons of the general population. Int. J. Hyg. Environ. Health 207 (2004) 531-539
24. Settels E., Bernauer U., Palavinskas R., Klaffke H.S., Gundert-Remy U., and Appel K.E. Human CYP2E1 mediates the formation of glycidamide from acrylamide. Arch. Toxicol. 82 (2008) 717-727
25. Sumner S.C.J., Fennell T.R., Moore T.A., Chanas B., Gonzalez F., and Ghanayem B.I. Role of cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice. Chem. Res. Toxicol. 12 (1999) 1110-1116
26. Tareke E., Rydberg P., Karlsson P., Eriksson S., and Törnqvist M. Acrylamide: a cooking carcinogen?. Chem. Res. Toxicol. 13 (2000) 517-522
27. Tareke E., Rydberg P., Karlsson P., Eriksson S., and Törnqvist M. Analysis of acrylamide, a carcinogen formed in heated foodstuffs. J. Agric. Food. Chem. 50 (2002) 4998-5006
28. Taubert D., Glöckner R., Müller D., and Schömig E. The garlic ingredient diallyl sulfide inhibits cytochrome P450 2E1 dependent bioactivation of acrylamide to glycidamide. Toxicol. Lett. 164 (2006) 1-5
29. Törnqvist M., Fred C., Haglund J., Helleberg H., Paulsson B., and Rydberg P. Protein adducts: quantitative and qualitative aspects of their formation, analysis and applications. J. Chromatogr. B 778 (2002) 279-308
30. Törnqvist M., Paulsson B., Vikström A.C., and Granath F. Approach for cancer risk estimation of acrylamide in food on the basis of animal cancer tests and in vivo dosimetry. J. Agric. Food Chem. 56 (2008) 6004-6012
31. Vesper H.W., Slimani N., Hallmans G., Tjønneland A., Agudo A., Benetou V., Bingham S., Boeing H., Boutron-Ruault M.C., Bueno-de-Mesquita H.B., Chirlaque D., Drogan D., Ferrari P., Johansson I., Kaaks R., Linseisen J., Lund E., Manjer E., Mattiello A., Palli D., Peeters P.H.M., Rinaldi S., Skeie G., Trichopoulou A., Vineis P., Wirfält E., Overvad K., and Strömberg U. Cross-sectional study on acrylamide hemoglobin adducts in subpopulations from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study. J. Am. Chem. Soc. 56 (2008) 6046-6053
32. Wilson K.M., Bälter K., Adami H.-O., Grönberg H., Vikström A.C., Paulsson B., Törnqvist M., and Mucci L.A. Acrylamide exposure and prostate cancer risk in the Cancer of the Prostate in Sweden study: a validation and case-control analysis. Int. J. Cancer 24 (2009) 2384-2390
33. Wilson K.M., Vesper H.W., Tocco P., Sampson L., Rosén J., Hellenäs K.E., Törnqvist M., and Willett W.C. Validation of a food frequency questionnaire measurement of dietary acrylamide intake using hemoglobin adducts of acrylamide and glycidamide. Cancer Causes Control 20 (2009) 269-278
34. Wirfalt E., Paulsson B., Törnqvist M., Axmon A., and Hagmar L. Associations between estimated acrylamide (AA) intakes, and Hb AA-adducts in a sample from the Malmö Diet and Cancer cohort. Eur. J. Clin. Nutr. 62 (2008) 314-323