Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ) - Synthesis and biological activity

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 9, 2003, Pages 1517-1521

  Sznaidman, Marcos L ^a,c   Haffner, Curt D ^a   Maloney, Patrick R ^a   Fivush, Adam ^a   Chao, Esther ^a   Goreham, Donna ^a   Sierra, Michael L ^b   LeGrumelec, Christelle ^b   Xu, H Eric ^a   Montana, Valerie G ^a   Lambert, Millard H ^a   Willson, Timothy M ^a   Oliver Jr , William R ^a   Sternbach, Daniel D ^a  

^a GLAXOSMITHKLINE   (United States)

^b GLAXOSMITHKLINE   (France)

^c Norak Biosciences Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; GW 0742; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; LIPOPHILICITY; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

EID: 12444289447     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00207-5     Document Type: Article

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