Interactions within the ubiquitin pathway of Caenorhabditis elegans

Biochemical and Biophysical Research Communications

Volumn 325, Issue 2, 2004, Pages 479-486

  Gudgen, Michelle ^a   Chandrasekaran, Anantharaman ^a   Frazier, Tyralynn ^a   Boyd, Lynn ^a  

^a UNIVERSITY OF ALABAMA IN HUNTSVILLE   (United States)

Author keywords

Mms2; Rad6; RING finger; Two hybrid; Ubc13; Ubiquitin conjugating enzyme; Ubiquitin conjugating enzyme variant; Ubiquitin ligase; Ubiquitination; Uev1

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; ISOENZYME; ISOPROTEIN; PROTEIN EUV 1; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME 1; UBIQUITIN CONJUGATING ENZYME 13; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME SUBUNIT; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CARRIER PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RECOMBINANT PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN; UBIQUITIN-PROTEIN LIGASE COMPLEXES;

CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 7644224798     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.10.047     Document Type: Article

References (48)

1. C.J. Sherr Principles of tumor suppression Cell 116 2004 235 246
2. S.J. Berke, and H.L. Paulson Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration Curr. Opin. Genet. Dev. 13 2003 253 261
3. C.A. Ross, and M.A. Poirier Protein aggregation and neurodegenerative disease Nat. Med. 10 Suppl. 2004 S10 17
4. A. Hershko, and A. Ciechanover The ubiquitin system Annu. Rev. Biochem. 67 1998 425 479
5. C.M. Pickart Mechanisms underlying ubiquitination Annu. Rev. Biochem. 70 2001 503 533
6. J. Peng, D. Schwartz, J.E. Elias, C.C. Thoreen, D. Cheng, G. Marsischky, J. Roelofs, D. Finley, and S.P. Gygi A proteomics approach to understanding protein ubiquitination Nat. Biotechnol. 21 2003 921 926
7. R.S. Kang, C.M. Daniels, S.A. Francis, S.C. Shih, W.J. Salerno, L. Hicke, and I. Radhakrishnan Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding Cell 113 2003 621 630
8. S.C. Shih, G. Prag, S.A. Francis, M.A. Sutanto, J.H. Hurley, and L. Hicke A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain EMBO J. 22 2003 1273 1281
9. S. Polo, S. Sigismund, M. Faretta, M. Guidi, M.R. Capua, G. Bossi, H. Chen, P. De Camilli, and P.P. Di Fiore A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins Nature 416 2002 451 455
10. M.D. Marmor, and Y. Yarden Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases Oncogene 23 2004 2057 2070
11. M. Hochstrasser Ubiquitin, proteasomes, and the regulation of intracellular protein degradation Curr. Opin. Cell Biol. 4 1995 1024 1031
12. J.S. Thrower, L. Hoffman, M. Rechsteiner, and C.M. Pickart Recognition of the polyubiquitin signal EMBO J. 19 2000 94 102
13. W. Dubiel, and C. Gordon Ubiquitin pathway: another link in the polyubiquitin chain? Curr. Biol. 9 1999 R554 557
14. N. Zheng, P. Wang, P.D. Jeffrey, and N.P. Pavletich Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases Cell 102 2000 533 539
15. L. Huang, E. Kinnucan, G. Wang, S. Beaudenon, P.M. Howley, J.M. Huibregtse, and N.P. Pavletich Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade Science 286 1999 1321 1326
16. A.D. Pham, and F. Sauer Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila Science 289 2000 2357 2360
17. E. Schulze, M.E. Altmann, I.M. Adham, B. Schulze, S. Frode, and W. Engel The maintenance of neuromuscular function requires UBC-25 in Caenorhabditis elegans Biochem. Biophys. Res. Commun. 305 2003 691 699
18. D. Jones, E. Crowe, T.A. Stevens, and P.M. Candido Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins Genome Biol. 3 2001 1 15
19. WormBase, in, 2003
20. S. Broomfield, B.L. Chow, and W. Xiao MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway Proc. Natl. Acad. Sci. USA 95 1998 5678 5683
21. R.M. Hofmann, and C.M. Pickart In vitro assembly and recognition of Lys-63 polyubiquitin chains J. Biol. Chem. 276 2001 27936 27943
22. L. Deng, C. Wang, E. Spencer, L. Yang, A. Braun, J. You, C. Slaughter, C. Pickart, and Z.J. Chen Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain Cell 103 2000 351 361
23. R.C. Aguilar, and B. Wendland Ubiquitin: not just for proteasomes anymore Curr. Opin. Cell Biol. 15 2003 184 190
24. C.M. Pickart Back to the future with ubiquitin Cell 116 2004 181 190
25. S. Broomfield, T. Hryciw, and W. Xiao DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae Mutat. Res. 486 2001 167 184
26. R.J. Dohmen, K. Madura, B. Bartel, and A. Varshavsky The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme Proc. Natl. Acad. Sci. USA 88 1991 7351 7355
27. C. Ashley, L. Pastushok, S. McKenna, M.J. Ellison, and W. Xiao Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination Gene 285 2002 183 191
28. S. McKenna, T. Moraes, L. Pastushok, C. Ptak, W. Xiao, L. Spyracopoulos, and M.J. Ellison An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysis J. Biol. Chem. 278 2003 13151 13158
29. R. Varadan, M. Assfalg, A. Haririnia, S. Raasi, C. Pickart, and D. Fushman Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling J. Biol. Chem. 279 2004 7055 7063
30. H. Zhou, I. Wertz, K. O'Rourke, M. Ultsch, S. Seshagiri, M. Eby, W. Xiao, and V.M. Dixit Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO Nature 427 2004 167 171
31. J. Bothos, M.K. Summers, M. Venere, D.M. Scolnick, and T.D. Halazonetis The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains Oncogene 22 2003 7101 7107
32. C.S. Shi, and J.H. Kehrl Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2) J. Biol. Chem. 278 2003 15429 15434
33. F. Wu-Baer, K. Lagrazon, W. Yuan, and R. Baer The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin J. Biol. Chem. 278 2003 34743 34746
34. H. Nishikawa, S. Ooka, K. Sato, K. Arima, J. Okamoto, R.E. Klevit, M. Fukuda, and T. Ohta Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase J. Biol. Chem. 279 2004 3916 3924
35. A.R. Venkitaraman Cancer susceptibility and the functions of BRCA1 and BRCA2 Cell 108 2002 171 182
36. S.J. Boulton, J.S. Martin, J. Polanowska, D.E. Hill, A. Gartner, and M. Vical BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans Curr. Biol. 14 2004 33 39
37. J. Reboul, P. Vaglio, J.F. Rual, P. Lamesch, M. Martinez, C.M. Armstrong, S. Li, L. Jacotot, N. Bertin, R. Janky, T. Moore, J.R. Hudson Jr., J.L. Hartley, M.A. Brasch, J. Vandenhaute, S. Boulton, G.A. Endress, S. Jenna, E. Chevet, V. Papasotiropoulos, P.P. Tolias, J. Ptacek, M. Snyder, R. Huang, M.R. Chance, H. Lee, L. Doucette-Stamm, D.E. Hill, and M. Vidal C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression Nat. Genet. 34 2003 35 41
38. P. James, J. Halladay, and E.A. Craig Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast Genetics 144 1996 14 25
39. T. Frazier, D. Shakes, U. Hota, L. Boyd, Caenorhabditis elegans UBC-2 functions with the anaphase-promoting complex but also has other activities, J. Cell Sci. 117 (2004), in press
40. R. Moore, and L. Boyd Analysis of RING finger genes required for embryogenesis in C. elegans Genesis 38 2004 1 12
41. L. Boyd, S. Guo, D. Levitan, D.T. Stinchcomb, and K.J. Kemphues PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos Development 122 1996 3075 3084
42. H. Thieringer, B. Moellers, G. Dodt, W.H. Kunau, and M. Driscoll Modeling human peroxisome biogenesis disorders in the nematode Caenorhabditis elegans J. Cell Sci. 116 2003 1797 1804
43. S. Li, C.M. Armstrong, N. Bertin, H. Ge, S. Milstein, M. Boxem, P.O. Vidalain, J.D. Han, A. Chesneau, T. Hao, D.S. Goldberg, N. Li, M. Martinez, J.F. Rual, P. Lamesch, L. Xu, M. Tewari, S.L. Wong, L.V. Zhang, G.F. Berriz, L. Jacotot, P. Vaglio, J. Reboul, T. Hirozane-Kishikawa, Q. Li, H.W. Gabel, A. Elewa, B. Baumgartner, D.J. Rose, H. Yu, S. Bosak, R. Sequerra, A. Fraser, S.E. Mango, W.M. Saxton, S. Strome, S. Van Den Heuvel, F. Piano, J. Vandenhaute, C. Sardet, M. Gerstein, L. Doucette-Stamm, K.C. Gunsalus, J.W. Harper, M.E. Cusick, F.P. Roth, D.E. Hill, and M. Vidal A map of the interactome network of the metazoan C. elegans Science 303 2004 540 543
44. E. Crowe, and E.P. Candido Characterization of C. elegans RING finger protein 1, a binding partner of ubiquitin-conjugating enzyme 1 Dev. Biol. 265 2004 446 459
45. D.S. Leggett, and P.M. Candido Biochemical characterization of Caenorhabditis elegans UBC-1: self-association and auto-ubiquitination of a RAD6-like ubiquitin-conjugating enzyme in vitro Biochem. J. 327 Pt 2 1997 357 361
46. C. Hoege, B. Pfander, G.L. Moldovan, G. Pyrowolakis, and S. Jentsch RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO Nature 419 2002 135 141
47. A.P. VanDemark, R.M. Hofmann, C. Tsui, C.M. Pickart, and C. Wolberger Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer Cell 105 2001 711 720
48. H.D. Ulrich, and S. Jentsch Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair EMBO J. 19 2000 3388 3397