Small peptide inhibitor of JNKs protects against MPTP-induced nigral dopaminergic injury via inhibiting the JNK-signaling pathway

Laboratory Investigation

Volumn 90, Issue 2, 2010, Pages 156-167

  Pan, Jing ^a   Qian, Jing ^a   Zhang, Yu ^a   Ma, Jianfang ^a   Wang, Gang ^a   Xiao, Qin ^a   Chen, Shengdi ^a   Ding, Jianqing ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Dopaminergic neuron; JIP 1; JNKs; Neuronal death; Tat JBD

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CASPASE 3; CYTOCHROME C; JNK INTERACTING PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN C JUN; PROTEIN INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; TAT JBD PROTEIN INHIBITOR; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOPRECIPITATION; MALE; MITOCHONDRION; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NIGRAL DOPAMINERGIC INJURY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; IN SITU NICK-END LABELING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 75949126311     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2009.124     Document Type: Article

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