Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated bax

Journal of Biological Chemistry

Volumn 279, Issue 42, 2004, Pages 43920-43928

  Zhang, Zhi ^a   Lapolla, Suzanne M ^a   Annis, Matthew G ^b   Truscott, Mary ^b   Roberts, G Jane ^b   Miao, Yiwei ^c   Shao, Yuanlong ^c   Tan, Chibing ^a   Peng, Jun ^a   Johnson, Arthur E ^c,d   Zhang, Xuejun C ^e   Andrews, David W ^b   Lin, Jialing ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b MCMASTER UNIVERSITY   (Canada)

^c TEXAS A M COLLEGE OF MEDICINE   (United States)

^d TEXAS A AND M UNIVERSITY   (United States)

^e OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; CROSSLINKING; DIMERS; HYDROPHOBICITY; MATHEMATICAL MODELS; MEMBRANES; OLIGOMERS; PROTEINS;

APOPTOTOC SIGNALS; BINDING SURFACES; HOMODIMERIZATION; PHOTOCROSS-LINKING;

DIMERIZATION;

INHIBITOR OF APOPTOSIS PROTEIN; OLIGOMER; PROTEIN BAX; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL FREE SYSTEM; CELL PROTECTION; CONTROLLED STUDY; DIMERIZATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; SURFACE PROPERTY;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BINDING SITES; CELL LINE; DIMERIZATION; GENE DELETION; HUMANS; MUTAGENESIS; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS; SEQUENCE DELETION; TRANSFECTION;

HOMO;

EID: 6344235539     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406412200     Document Type: Article

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