-
1
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-57.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
2
-
-
67649427346
-
The role of hypoxia-inducible transcription factors in the hypoxic neonatal brain
-
Trollmann R, Gassmann M. The role of hypoxia-inducible transcription factors in the hypoxic neonatal brain. Brain Dev 2009;31:503-9.
-
(2009)
Brain Dev
, vol.31
, pp. 503-509
-
-
Trollmann, R.1
Gassmann, M.2
-
3
-
-
64849116779
-
The role of vascular endothelial growth factor in wound healing
-
Bao P, Kodra A, Tomic-Canic M, Golinko MS, Ehrlich HP, Brem H. The role of vascular endothelial growth factor in wound healing. J Surg Res 2009;153:347-58.
-
(2009)
J Surg Res
, vol.153
, pp. 347-358
-
-
Bao, P.1
Kodra, A.2
Tomic-Canic, M.3
Golinko, M.S.4
Ehrlich, H.P.5
Brem, H.6
-
4
-
-
44449142547
-
Angiogenesis detected after embolic stroke in rat brain using magnetic resonance T2*WI
-
Ding G, Jiang Q, Li L, et al. Angiogenesis detected after embolic stroke in rat brain using magnetic resonance T2*WI. Stroke 2008;39:1563-8.
-
(2008)
Stroke
, vol.39
, pp. 1563-1568
-
-
Ding, G.1
Jiang, Q.2
Li, L.3
-
5
-
-
64249131156
-
Circulating biomarkers of angiogenesis as indicators of left ventricular systolic dysfunction amongst patients with coronary artery disease
-
Patel JV, Abraheem A, Chackathayil J, et al. Circulating biomarkers of angiogenesis as indicators of left ventricular systolic dysfunction amongst patients with coronary artery disease. J Intern Med 2009;265:562-7.
-
(2009)
J Intern Med
, vol.265
, pp. 562-567
-
-
Patel, J.V.1
Abraheem, A.2
Chackathayil, J.3
-
6
-
-
21444439235
-
Vascular endothelial growth factor and diabetic retinopathy: Role of oxidative stress
-
Caldwell RB, Bartoli M, Behzadian MA, et al. Vascular endothelial growth factor and diabetic retinopathy: role of oxidative stress. Curr Drug Targets 2005;6:511-24.
-
(2005)
Curr Drug Targets
, vol.6
, pp. 511-524
-
-
Caldwell, R.B.1
Bartoli, M.2
Behzadian, M.A.3
-
7
-
-
63749109585
-
-
online exclusive article, PLoS One 2009;4:e4974. Available from
-
Tam J, Duda DG, Perentes JY, Quadri RS, Fukumura D, Jain RK. Blockade of VEGFR2 and not VEGFR1 can limit dietinduced fat tissue expansion: role of local versus bone marrow - derived endothelial cells [online exclusive article]. PLoS One 2009;4:e4974. Available from http://www.plosone.org/article/ info:doi/10.1371/journal.pone.0004974.
-
Blockade of VEGFR2 and not VEGFR1 can limit dietinduced fat tissue expansion: Role of local versus bone marrow - derived endothelial cells
-
-
Tam, J.1
Duda, D.G.2
Perentes, J.Y.3
Quadri, R.S.4
Fukumura, D.5
Jain, R.K.6
-
8
-
-
0033617532
-
Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
-
Bergers G, Javaherian K, Lo KM, Folkman J, Hanahan D. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science 1999;284:808-12.
-
(1999)
Science
, vol.284
, pp. 808-812
-
-
Bergers, G.1
Javaherian, K.2
Lo, K.M.3
Folkman, J.4
Hanahan, D.5
-
9
-
-
33646945885
-
The HMG-CoA reductase pathway, statins and angioprevention
-
Feng C, Han A, Ye C, Xu R, Li M. The HMG-CoA reductase pathway, statins and angioprevention. Semin Ophthalmol 2006;21:29-35.
-
(2006)
Semin Ophthalmol
, vol.21
, pp. 29-35
-
-
Feng, C.1
Han, A.2
Ye, C.3
Xu, R.4
Li, M.5
-
10
-
-
2442621619
-
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
-
Ferrara N, Hillan KJ, Gerber HP, Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 2004;3:391-400.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 391-400
-
-
Ferrara, N.1
Hillan, K.J.2
Gerber, H.P.3
Novotny, W.4
-
13
-
-
0037420492
-
Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian cardiac outcomes trial - lipid lowering arm (ASCOT-LLA): A multicentre randomised controlled trial
-
Sever PS, Dahlof B, Poulter NR, et al. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian cardiac outcomes trial - lipid lowering arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003;361:1149-58.
-
(2003)
Lancet
, vol.361
, pp. 1149-1158
-
-
Sever, P.S.1
Dahlof, B.2
Poulter, N.R.3
-
14
-
-
0032554676
-
Influence of pravastatin and plasma lipids on clinical events in the West of Scotland coronary prevention study (WOSCOPS)
-
The West of Scotland Coronary Prevention Study Group
-
The West of Scotland Coronary Prevention Study Group. Influence of pravastatin and plasma lipids on clinical events in the West of Scotland coronary prevention study (WOSCOPS). Circulation 1998;97:1440-5.
-
(1998)
Circulation
, vol.97
, pp. 1440-1445
-
-
-
15
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian simvastatin survival study (4S)
-
The Scandinavian Simvastatin Survival Study Group
-
The Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian simvastatin survival study (4S). Lancet 1994;344:1383-9.
-
(1994)
Lancet
, vol.344
, pp. 1383-1389
-
-
-
16
-
-
4344683381
-
Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the collaborative atorvastatin diabetes study (CARDS): Multicentre randomised placebo-controlled trial
-
for the CARDS Investigators
-
Colhoun HM, Betteridge DJ, Durrington PN, et al, for the CARDS Investigators. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the collaborative atorvastatin diabetes study (CARDS): multicentre randomised placebo-controlled trial. Lancet 2004;364:685-96.
-
(2004)
Lancet
, vol.364
, pp. 685-696
-
-
Colhoun, H.M.1
Betteridge, D.J.2
Durrington, P.N.3
-
17
-
-
0032926503
-
Reduction of stroke incidence after myocardial infarction with pravastatin: The cholesterol and recurrent events (CARE) study
-
for the CARE Investigators
-
Plehn JF, Davis BR, Sacks FM, et al, for the CARE Investigators. Reduction of stroke incidence after myocardial infarction with pravastatin: the cholesterol and recurrent events (CARE) study. Circulation 1999;99:216-23.
-
(1999)
Circulation
, vol.99
, pp. 216-223
-
-
Plehn, J.F.1
Davis, B.R.2
Sacks, F.M.3
-
18
-
-
33746895436
-
High-dose atorvastatin after stroke or transient ischemic attack
-
Amarenco P, Bogousslavsky J, Callahan A III, et al. High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med 2006;355:549-59.
-
(2006)
N Engl J Med
, vol.355
, pp. 549-559
-
-
Amarenco, P.1
Bogousslavsky, J.2
Callahan III, A.3
-
19
-
-
56749106312
-
Rosuvastatin to prevent vascular events in men and women with elevated Creactive protein
-
Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated Creactive protein. N Engl J Med 2008;359:2195-207.
-
(2008)
N Engl J Med
, vol.359
, pp. 2195-2207
-
-
Ridker, P.M.1
Danielson, E.2
Fonseca, F.A.3
-
20
-
-
0032555154
-
Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
-
Endres M, Laufs U, Huang Z, et al. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc Natl Acad Sci USA 1998;95:8880-5.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8880-8885
-
-
Endres, M.1
Laufs, U.2
Huang, Z.3
-
21
-
-
0037189048
-
Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice
-
Laufs U, Gertz K, Dirnagl U, Bohm M, Nickenig G, Endres M. Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice. Brain Res 2002;942:23-30.
-
(2002)
Brain Res
, vol.942
, pp. 23-30
-
-
Laufs, U.1
Gertz, K.2
Dirnagl, U.3
Bohm, M.4
Nickenig, G.5
Endres, M.6
-
22
-
-
0036829777
-
Beyond lipid lowering: The role of statins in vascular protection
-
Liao JK. Beyond lipid lowering: the role of statins in vascular protection. Int J Cardiol 2002;86:5-18.
-
(2002)
Int J Cardiol
, vol.86
, pp. 5-18
-
-
Liao, J.K.1
-
23
-
-
0032826065
-
Neuroprotective properties of statins in cerebral ischemia and stroke
-
Vaughan CJ, Delanty N. Neuroprotective properties of statins in cerebral ischemia and stroke. Stroke 1999;30:1969-73.
-
(1999)
Stroke
, vol.30
, pp. 1969-1973
-
-
Vaughan, C.J.1
Delanty, N.2
-
24
-
-
67651011803
-
Early atorvastatin reduces hemorrhage after acute cerebral ischemia in diabetic rats
-
Elewa HF, Kozak A, El-Remessy AB, et al. Early atorvastatin reduces hemorrhage after acute cerebral ischemia in diabetic rats. J Pharmacol Exp Ther 2009;330:532-40.
-
(2009)
J Pharmacol Exp Ther
, vol.330
, pp. 532-540
-
-
Elewa, H.F.1
Kozak, A.2
El-Remessy, A.B.3
-
25
-
-
36049028936
-
The PI3K/Akt pathway mediates the neuroprotective effect of atorvastatin in extending thrombolytic therapy after embolic stroke in the rat
-
Zhang L, Zhang ZG, Liu XS, Hozeska-Solgot A, Chopp M. The PI3K/Akt pathway mediates the neuroprotective effect of atorvastatin in extending thrombolytic therapy after embolic stroke in the rat. Arterioscler Thromb Vasc Biol 2007;27:2470-5.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 2470-2475
-
-
Zhang, L.1
Zhang, Z.G.2
Liu, X.S.3
Hozeska-Solgot, A.4
Chopp, M.5
-
26
-
-
0033826581
-
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals
-
Kureishi Y, Luo Z, Shiojima I, et al. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med 2000;6:1004-10.
-
(2000)
Nat Med
, vol.6
, pp. 1004-1010
-
-
Kureishi, Y.1
Luo, Z.2
Shiojima, I.3
-
27
-
-
48249088030
-
Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy
-
Al-Shabrawey M, Bartoli M, El-Remessy AB, et al. Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy. Invest Ophthalmol Vis Sci 2008;49:3231-8.
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 3231-3238
-
-
Al-Shabrawey, M.1
Bartoli, M.2
El-Remessy, A.B.3
-
28
-
-
59449096216
-
Novel aspects of oxidative stress in cardiovascular diseases
-
Heistad DD, Wakisaka Y, Miller J, Chu Y, Pena-Silva R. Novel aspects of oxidative stress in cardiovascular diseases. Circ J 2009;73:201-7.
-
(2009)
Circ J
, vol.73
, pp. 201-207
-
-
Heistad, D.D.1
Wakisaka, Y.2
Miller, J.3
Chu, Y.4
Pena-Silva, R.5
-
29
-
-
12844260208
-
Atorvastatin induction of VEGF and BDNF promotes brain plasticity after stroke in mice
-
Chen J, Zhang C, Jiang H, et al. Atorvastatin induction of VEGF and BDNF promotes brain plasticity after stroke in mice. J Cereb Blood Flow Metab 2005;25:281-90.
-
(2005)
J Cereb Blood Flow Metab
, vol.25
, pp. 281-290
-
-
Chen, J.1
Zhang, C.2
Jiang, H.3
-
30
-
-
44949131802
-
Combination of simvastatin administration and EPC transplantation enhances angiogenesis and protects against apoptosis for hindlimb ischemia
-
Hu Z, Zhang F, Yang Z, et al. Combination of simvastatin administration and EPC transplantation enhances angiogenesis and protects against apoptosis for hindlimb ischemia. J Biomed Sci 2008;15:509-17.
-
(2008)
J Biomed Sci
, vol.15
, pp. 509-517
-
-
Hu, Z.1
Zhang, F.2
Yang, Z.3
-
31
-
-
41349103941
-
Simvastatin stimulates vascular endothelial growth factor production by hypoxia-inducible factor-1α upregulation in endothelial cells
-
Nishimoto-Hazuku A, Hirase T, Ide N, Ikeda Y, Node K. Simvastatin stimulates vascular endothelial growth factor production by hypoxia-inducible factor-1α upregulation in endothelial cells. J Cardiovasc Pharmacol 2008;51:267-73.
-
(2008)
J Cardiovasc Pharmacol
, vol.51
, pp. 267-273
-
-
Nishimoto-Hazuku, A.1
Hirase, T.2
Ide, N.3
Ikeda, Y.4
Node, K.5
-
32
-
-
58849167638
-
Stimulatory effects of low-dose 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin on hepatocyte growth factor-induced angiogenesis: Involvement of p38 mitogen-activated protein kinase
-
Uruno A, Sugawara A, Kudo M, Satoh F, Saito A, Ito S. Stimulatory effects of low-dose 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin on hepatocyte growth factor-induced angiogenesis: involvement of p38 mitogen-activated protein kinase. Hypertens Res 2008;31:2085-96.
-
(2008)
Hypertens Res
, vol.31
, pp. 2085-2096
-
-
Uruno, A.1
Sugawara, A.2
Kudo, M.3
Satoh, F.4
Saito, A.5
Ito, S.6
-
33
-
-
5644290906
-
Simvastatin induces proliferation inhibition and apoptosis in C6 glioma cells via cjun N-terminal kinase
-
Koyuturk M, Ersoz M, Altiok N. Simvastatin induces proliferation inhibition and apoptosis in C6 glioma cells via cjun N-terminal kinase. Neurosci Lett 2004;370:212-17.
-
(2004)
Neurosci Lett
, vol.370
, pp. 212-217
-
-
Koyuturk, M.1
Ersoz, M.2
Altiok, N.3
-
34
-
-
0034777844
-
Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin
-
Wong WW, Tan MM, Xia Z, Dimitroulakos J, Minden MD, Penn LZ. Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin. Clin Cancer Res 2001;7:2067-75.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2067-2075
-
-
Wong, W.W.1
Tan, M.M.2
Xia, Z.3
Dimitroulakos, J.4
Minden, M.D.5
Penn, L.Z.6
-
36
-
-
28544438656
-
Biphasic effect of HMG-CoA reductase inhibitor, pitavastatin, on vascular endothelial cells and angiogenesis
-
Katsumoto M, Shingu T, Kuwashima R, Nakata A, Nomura S, Chayama K. Biphasic effect of HMG-CoA reductase inhibitor, pitavastatin, on vascular endothelial cells and angiogenesis. Circ J 2005;69:1547-55.
-
(2005)
Circ J
, vol.69
, pp. 1547-1555
-
-
Katsumoto, M.1
Shingu, T.2
Kuwashima, R.3
Nakata, A.4
Nomura, S.5
Chayama, K.6
-
37
-
-
55749092758
-
Disparate effects of simvastatin on angiogenesis during hypoxia and inflammation
-
Zhu XY, Daghini E, Chade AR, et al. Disparate effects of simvastatin on angiogenesis during hypoxia and inflammation. Life Sci 2008;83:801-9.
-
(2008)
Life Sci
, vol.83
, pp. 801-809
-
-
Zhu, X.Y.1
Daghini, E.2
Chade, A.R.3
-
38
-
-
36949033817
-
Emerging indications for statins: A pluripotent family of agents with several potential applications
-
Paraskevas KI, Tzovaras AA, Briana DD, Mikhailidis DP. Emerging indications for statins: a pluripotent family of agents with several potential applications. Curr Pharm Des 2007;13:3622-36.
-
(2007)
Curr Pharm Des
, vol.13
, pp. 3622-3636
-
-
Paraskevas, K.I.1
Tzovaras, A.A.2
Briana, D.D.3
Mikhailidis, D.P.4
-
40
-
-
70349577808
-
HMG-CoA reductase inhibitors (statins) prevents retinal neovascularization in a model of oxygen-induced retinopathy
-
Bartoli M, Al-Shabrawey M, Labazi M, et al. HMG-CoA reductase inhibitors (statins) prevents retinal neovascularization in a model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci 2009;50:4934-40.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 4934-4940
-
-
Bartoli, M.1
Al-Shabrawey, M.2
Labazi, M.3
-
42
-
-
0019332724
-
Synthesis of delta 2-isopentenyl tRNA from mevalonate in cultured human fibroblasts
-
Faust JR, Brown MS, Goldstein JL. Synthesis of delta 2-isopentenyl tRNA from mevalonate in cultured human fibroblasts. J Biol Chem 1980;255:6546-8.
-
(1980)
J Biol Chem
, vol.255
, pp. 6546-6548
-
-
Faust, J.R.1
Brown, M.S.2
Goldstein, J.L.3
-
43
-
-
25644449640
-
Pathophysiological consequences of VEGF-induced vascular permeability
-
Weis SM, Cheresh DA. Pathophysiological consequences of VEGF-induced vascular permeability. Nature 2005;437:497-504.
-
(2005)
Nature
, vol.437
, pp. 497-504
-
-
Weis, S.M.1
Cheresh, D.A.2
-
44
-
-
4344639706
-
Targets for vascular protection after acute ischemic stroke
-
Fagan SC, Hess DC, Hohnadel EJ, Pollock DM, Ergul A. Targets for vascular protection after acute ischemic stroke. Stroke 2004;35:2220-5.
-
(2004)
Stroke
, vol.35
, pp. 2220-2225
-
-
Fagan, S.C.1
Hess, D.C.2
Hohnadel, E.J.3
Pollock, D.M.4
Ergul, A.5
-
45
-
-
42949163976
-
Effects of erythropoietin after an acute myocardial infarction: Rationale and study design of a prospective, randomized, clinical trial (HEBE III)
-
Belonje AM, Voors AA, van Gilst WH, et al. Effects of erythropoietin after an acute myocardial infarction: rationale and study design of a prospective, randomized, clinical trial (HEBE III). Am Heart J 2008;155:817-22.
-
(2008)
Am Heart J
, vol.155
, pp. 817-822
-
-
Belonje, A.M.1
Voors, A.A.2
van Gilst, W.H.3
-
46
-
-
33845225092
-
Protective effects of erythropoietin in cardiac ischemia: From bench to bedside
-
Lipsic E, Schoemaker RG, van der Meer P, Voors AA, van Veldhuisen DJ, van Gilst WH. Protective effects of erythropoietin in cardiac ischemia: from bench to bedside. J Am Coll Cardiol 2006;48:2161-7.
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 2161-2167
-
-
Lipsic, E.1
Schoemaker, R.G.2
van der Meer, P.3
Voors, A.A.4
van Veldhuisen, D.J.5
van Gilst, W.H.6
-
47
-
-
27744472350
-
HMG-CoA reductase inhibition modulates VEGF-induced endothelial cell hyperpermeability by preventing RhoA activation and myosin regulatory light chain phosphorylation
-
Zeng L, Xu H, Chew TL, et al. HMG-CoA reductase inhibition modulates VEGF-induced endothelial cell hyperpermeability by preventing RhoA activation and myosin regulatory light chain phosphorylation. FASEB J 2005;19:1845-7.
-
(2005)
FASEB J
, vol.19
, pp. 1845-1847
-
-
Zeng, L.1
Xu, H.2
Chew, T.L.3
-
48
-
-
0032487931
-
Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
-
The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
-
The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998;339:1349-57.
-
(1998)
N Engl J Med
, vol.339
, pp. 1349-1357
-
-
-
49
-
-
59949099437
-
Diabetic retinopathy: Current management and experimental therapeutic targets
-
Ali TK, El-Remessy AB. Diabetic retinopathy: current management and experimental therapeutic targets. Pharmacotherapy 2009;29:182-92.
-
(2009)
Pharmacotherapy
, vol.29
, pp. 182-192
-
-
Ali, T.K.1
El-Remessy, A.B.2
-
50
-
-
50249141649
-
-
online exclusive article, PLoS One 2008; 3:e2584. Available from
-
Medina RJ, O'Neill CL, Devine AB, Gardiner TA, Stitt AW. The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathies [online exclusive article]. PLoS One 2008; 3:e2584. Available from http://www.plosone.org/article/info:doi/ 10.1371/journal.pone.0002584.
-
The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathies
-
-
Medina, R.J.1
O'Neill, C.L.2
Devine, A.B.3
Gardiner, T.A.4
Stitt, A.W.5
-
51
-
-
11144239923
-
Pegaptanib for neovascular age-related macular degeneration
-
Gragoudas ES, Adamis AP, Cunningham ET Jr, Feinsod M, Guyer DR. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med 2004;351:2805-16.
-
(2004)
N Engl J Med
, vol.351
, pp. 2805-2816
-
-
Gragoudas, E.S.1
Adamis, A.P.2
Cunningham Jr, E.T.3
Feinsod, M.4
Guyer, D.R.5
-
52
-
-
33645641520
-
-
Heier JS, Antoszyk AN, Pavan PR, et al. Ranibizumab for treatment of neovascular age-related macular degeneration: a phase I/II multicenter, controlled, multidose study. Ophthalmology 2006;113:633.e1-4.
-
Heier JS, Antoszyk AN, Pavan PR, et al. Ranibizumab for treatment of neovascular age-related macular degeneration: a phase I/II multicenter, controlled, multidose study. Ophthalmology 2006;113:633.e1-4.
-
-
-
-
53
-
-
65349135042
-
Intravitreal bevacizumab (Avastin) prevention of panretinal photocoagulation-induced complications in patients with severe proliferative diabetic retinopathy
-
Mason JO III, Yunker JJ, Vail R, McGwin G Jr. Intravitreal bevacizumab (Avastin) prevention of panretinal photocoagulation-induced complications in patients with severe proliferative diabetic retinopathy. Retina 2008;18:1319-24.
-
(2008)
Retina
, vol.18
, pp. 1319-1324
-
-
Mason III, J.O.1
Yunker, J.J.2
Vail, R.3
McGwin Jr., G.4
-
54
-
-
70349750575
-
Short-term efficacy of intravitreal bevacizumab for the treatment of macular edema due to diabetic retinopathy and retinal vein occlusion
-
Astam N, Batioglu F, Ozmert E. Short-term efficacy of intravitreal bevacizumab for the treatment of macular edema due to diabetic retinopathy and retinal vein occlusion. Int Ophthalmol 2009;29:343-8.
-
(2009)
Int Ophthalmol
, vol.29
, pp. 343-348
-
-
Astam, N.1
Batioglu, F.2
Ozmert, E.3
-
55
-
-
33645331188
-
-
Rosenfeld PJ, Heier JS, Hantsbarger G, Shams N. Tolerability and efficacy of multiple escalating doses of ranibizumab (Lucentis) for neovascular age-related macular degeneration. Ophthalmology 2006;113:623-32.e1.
-
Rosenfeld PJ, Heier JS, Hantsbarger G, Shams N. Tolerability and efficacy of multiple escalating doses of ranibizumab (Lucentis) for neovascular age-related macular degeneration. Ophthalmology 2006;113:623-32.e1.
-
-
-
-
56
-
-
0037840242
-
MRC/BHF heart protection study of cholesterol-lowering with simvastatin in 5963 people with diabetes: A randomised placebo-controlled trial
-
for the Heart Protection Study Group
-
Collins R, Armitage J, Parish S, Sleigh P, Peto R, for the Heart Protection Study Group. MRC/BHF heart protection study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet 2003;361:2005-16.
-
(2003)
Lancet
, vol.361
, pp. 2005-2016
-
-
Collins, R.1
Armitage, J.2
Parish, S.3
Sleigh, P.4
Peto, R.5
-
57
-
-
22544484807
-
Statin attenuates high glucose-induced and diabetes-induced oxidative stress in vitro and in vivo evaluated by electron spin resonance measurement
-
Tsubouchi H, Inoguchi T, Sonta T, et al. Statin attenuates high glucose-induced and diabetes-induced oxidative stress in vitro and in vivo evaluated by electron spin resonance measurement. Free Radic Biol Med 2005;39:444-52.
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 444-452
-
-
Tsubouchi, H.1
Inoguchi, T.2
Sonta, T.3
-
58
-
-
51649123760
-
A review of Judah Folkman's remarkable achievements in biomedicine
-
Cao Y, Langer R. A review of Judah Folkman's remarkable achievements in biomedicine. Proc Natl Acad Sci USA 2008;105:13203-5.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13203-13205
-
-
Cao, Y.1
Langer, R.2
-
59
-
-
0028935780
-
Protein lipidation in cell signaling
-
Casey PJ. Protein lipidation in cell signaling. Science 1995;268:221-5.
-
(1995)
Science
, vol.268
, pp. 221-225
-
-
Casey, P.J.1
-
60
-
-
0032487933
-
Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53
-
Rao S, Lowe M, Herliczek TW, Keyomarsi K. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53. Oncogene 1998;17:2393-402.
-
(1998)
Oncogene
, vol.17
, pp. 2393-2402
-
-
Rao, S.1
Lowe, M.2
Herliczek, T.W.3
Keyomarsi, K.4
-
61
-
-
0032534660
-
Dolichol-like lipids with stimulatory effect on DNA synthesis: Substrates for protein dolichylation?
-
Wejde J, Hjertman M, Carlberg M, et al. Dolichol-like lipids with stimulatory effect on DNA synthesis: substrates for protein dolichylation? J Cell Biochem 1998;71:502-14.
-
(1998)
J Cell Biochem
, vol.71
, pp. 502-514
-
-
Wejde, J.1
Hjertman, M.2
Carlberg, M.3
-
62
-
-
0034908034
-
Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: An in vitro study
-
Denoyelle C, Vasse M, Korner M, et al. Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study. Carcinogenesis 2001;22:1139-48.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1139-1148
-
-
Denoyelle, C.1
Vasse, M.2
Korner, M.3
-
63
-
-
4544332780
-
Beta4 integrin is involved in statin-induced endothelial cell death
-
Feng C, Ye C, Liu X, Ma H, Li M. Beta4 integrin is involved in statin-induced endothelial cell death. Biochem Biophys Res Commun 2004;323:858-64.
-
(2004)
Biochem Biophys Res Commun
, vol.323
, pp. 858-864
-
-
Feng, C.1
Ye, C.2
Liu, X.3
Ma, H.4
Li, M.5
-
64
-
-
18344389025
-
Lovastatin-induced apoptosis in human melanoma cell lines
-
Shellman YG, Ribble D, Miller L, et al. Lovastatin-induced apoptosis in human melanoma cell lines. Melanoma Res 2005;15:83-9.
-
(2005)
Melanoma Res
, vol.15
, pp. 83-89
-
-
Shellman, Y.G.1
Ribble, D.2
Miller, L.3
-
65
-
-
20244380051
-
Different anticancer effects of fluvastatin on primary hepatocellular tumors and metastases in rats
-
Paragh G, Foris G, Paragh G Jr, et al. Different anticancer effects of fluvastatin on primary hepatocellular tumors and metastases in rats. Cancer Lett 2005;222:17-22.
-
(2005)
Cancer Lett
, vol.222
, pp. 17-22
-
-
Paragh, G.1
Foris, G.2
Paragh Jr, G.3
-
66
-
-
20044366735
-
A phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix
-
Knox JJ, Siu LL, Chen E, et al. A phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix. Eur J Cancer 2005;41:523-30.
-
(2005)
Eur J Cancer
, vol.41
, pp. 523-530
-
-
Knox, J.J.1
Siu, L.L.2
Chen, E.3
-
67
-
-
17744394863
-
Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma: A randomized controlled trial
-
Kawata S, Yamasaki E, Nagase T, et al. Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma: a randomized controlled trial. Br J Cancer 2001;84:886-91.
-
(2001)
Br J Cancer
, vol.84
, pp. 886-891
-
-
Kawata, S.1
Yamasaki, E.2
Nagase, T.3
-
68
-
-
22144475770
-
Association of statin use with a pathologic complete response to neoadjuvant chemoradiation for rectal cancer
-
Katz MS, Minsky BD, Saltz LB, Riedel E, Chessin DB, Guillem JG. Association of statin use with a pathologic complete response to neoadjuvant chemoradiation for rectal cancer. Int J Radiat Oncol Biol Phys 2005;62:1363-70.
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.62
, pp. 1363-1370
-
-
Katz, M.S.1
Minsky, B.D.2
Saltz, L.B.3
Riedel, E.4
Chessin, D.B.5
Guillem, J.G.6
-
69
-
-
3042515535
-
Treatment of HCC with pravastatin, octreotide, or gemcitabine: A critical evaluation
-
Klersch C, Schmelz R, Erdmann J, et al. Treatment of HCC with pravastatin, octreotide, or gemcitabine: a critical evaluation. Hepatogastroenterology 2004;51:1099-103.
-
(2004)
Hepatogastroenterology
, vol.51
, pp. 1099-1103
-
-
Klersch, C.1
Schmelz, R.2
Erdmann, J.3
-
70
-
-
49949097870
-
Phase II study of metronomic chemotherapy with thalidomide, carboplatin-vincristine-fluvastatin in the treatment of brain stem tumors in children
-
Lopez-Aguilar E, Sepulveda-Vildosola AC, Betanzos-Cabrera Y, et al. Phase II study of metronomic chemotherapy with thalidomide, carboplatin-vincristine-fluvastatin in the treatment of brain stem tumors in children. Arch Med Res 2008;39:655-62.
-
(2008)
Arch Med Res
, vol.39
, pp. 655-662
-
-
Lopez-Aguilar, E.1
Sepulveda-Vildosola, A.C.2
Betanzos-Cabrera, Y.3
-
71
-
-
0036227123
-
Statin use and the risk of breast and prostate cancer
-
Coogan PF, Rosenberg L, Palmer JR, Strom BL, Zauber AG, Shapiro S. Statin use and the risk of breast and prostate cancer. Epidemiology 2002;13:262-7.
-
(2002)
Epidemiology
, vol.13
, pp. 262-267
-
-
Coogan, P.F.1
Rosenberg, L.2
Palmer, J.R.3
Strom, B.L.4
Zauber, A.G.5
Shapiro, S.6
-
72
-
-
0030010318
-
Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer
-
Thibault A, Samid D, Tompkins AC, et al. Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer. Clin Cancer Res 1996;2:483-91.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 483-491
-
-
Thibault, A.1
Samid, D.2
Tompkins, A.C.3
|