Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53

Oncogene

Volumn 17, Issue 18, 1998, Pages 2393-2402

  Rao, Sharmila ^a   Lowe, Michael ^a   Herliczek, Thaddeus W ^a   Keyomarsi, Khandan ^a,b  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Adaptor molecule; CDKs; Cell cycle; CKIs; Cyclins; Lovastatin

Indexed keywords

ANTIMITOTIC AGENT; CYCLIN DEPENDENT KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; PROTEIN P21; PROTEIN P27; PROTEIN P53; RETINOBLASTOMA PROTEIN;

ARTICLE; BREAST CELL; BREAST TUMOR; CELL CYCLE G1 PHASE; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0032487933     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202322     Document Type: Article

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