Thermodynamics of CFTR channel gating: A spreading conformational change initiates an irreversible gating cycle

Journal of General Physiology

Volumn 128, Issue 5, 2006, Pages 523-533

  Csanády, László ^a   Nairn, Angus C ^b   Gadsby, David C ^b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLYLIMIDODIPHOSPHATE; MUTANT PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; CELL CYCLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; HUMAN; HYDROLYSIS KINETICS; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY; THERMODYNAMICS; XENOPUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FEMALE; HUMANS; HYDROLYSIS; ION CHANNEL GATING; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; TEMPERATURE; THERMODYNAMICS; XENOPUS LAEVIS;

EID: 33750499982     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200609558     Document Type: Article

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