Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 1, 2002, Pages 495-500

  Contreras, Jorge E ^a   Sánchez, Helmut A ^a   Eugenin, Eliseo A ^a   Speidel, Dina ^a   Theis, Martin ^a   Willecke, Klaus ^a   Bukauskas, Feliksas F ^a   Bennett, Michael V L ^a   Sáez, Juan C ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Astroglia; Cx43; Dye coupling; Dye uptake; Phosphorylation

Indexed keywords

18ALPHA GLYCYRRHETINIC ACID; ADENOSINE TRIPHOSPHATE DERIVATIVE; ARACHIDONIC ACID; CONNEXIN 43; DEXTRAN; DNA; ETHIDIUM BROMIDE; ION CHANNEL; LACTATE DEHYDROGENASE; LANTHANUM; LIPOXYGENASE; LUCIFER YELLOW; OCTANOL; SCAVENGER;

AEROBIC METABOLISM; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL DEATH; CELL PERMEABILIZATION; CONTROLLED STUDY; EMBRYO; ENZYME RELEASE; GAP JUNCTION; GENE DELETION; GLYCOLYSIS; ION TRANSPORT; ISCHEMIA; METABOLIC INHIBITION; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; ASTROCYTES; CALCIUM; CELLS, CULTURED; CONNEXIN 43; DEXTRANS; ETHIDIUM; FLUORESCENT DYES; FREE RADICAL SCAVENGERS; GAP JUNCTIONS; GLYCYRRHETINIC ACID; HUMANS; INTERCALATING AGENTS; IONS; ISOQUINOLINES; L-LACTATE DEHYDROGENASE; LANTHANUM; LIPOXYGENASE INHIBITORS; MICE; PROTEIN BINDING; RATS; RECOMBINANT FUSION PROTEINS; TIME FACTORS;

ANIMALIA; LETHRINIDAE;

EID: 0037039391     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.012589799     Document Type: Article

References (35)