Endothelin-1 regulates glucose utilization in cultured astrocytes by controlling intercellular communication through gap junctions

GLIA

Volumn 16, Issue 3, 1996, Pages 187-195

  Tabernero, Arantxa ^a   Giaume, Christian ^b   Medina, José M ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b PSL Research University   (France)

Author keywords

Astrocyte; Endothelin 1; Gap junctions; Glucose utilization

Indexed keywords

EID: 0030110740     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1098-1136(199603)16:3<187::aid-glia1>3.0.co;2-%23     Document Type: Article

References (38)

1. Bennett, M.V.L., Barrio, T.A , Bargiello, T.A., Spray, D.C., Hertzberg, E. and Sáez, J.C. (1991) Gap junctions: New tools, new answers, new questions, Neuron, 6:305-320.
2. Bergmeyer, H.U., Bernt, E., Schmidt, F., and Stork, H. (1974) D-glucose determination with hexokinase and glucose-6-phosphate dehydrogenase. In: Methods of Enzymatic Analysis. H.U. Bergmeyer, ed. Verlag Chemie International, Deerfield Beach, FL, Vol. 3, pp. 1196-1201.
3. Bignami, A., Eng, L.F., Dahl, D., and Uyeda, C.T. (1972) Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence. Brain Res., 43:429-435.
4. Binmoller, F.J. and Muller, C.M. (1992) Postnatal-development of dye-coupling among astrocytes in rat vixual-cortex. Glia, 6:127-137.
5. Brookes, N. And Yarowssy, P J. (1985) Determinants of deoxyglucose uptake in cultured astrocytes: the role of the sodium pump. J. Neurochem., 44:473-479.
6. Cataldo, A.M and Broadwell, R.D. (1986) Cytochemical identification of cerebral glycogen and glucose-6-phosphatase activity under normal and expeirmental conditions. I. Neurons and glia. J. Electron Microsc. Tech., 3:413-437.
7. Cintra, A.K., Fuxe, E., Anggard, E., Tinner, B., Staines, W., and Agnati, L.F. (1989) Increased endothelin-like immunoreactivity in ibotenic acid-lesioned hippocampal formation of the rat brain. Acta Physiol. Scand., 137:557-558.
8. Davidson, J.S., Baumgarten, I.M., and Harley, E.H. (1986) Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid. Biochem. Biophys. Res. Com., 134:29-36.
9. Dringen, R., Gebhardt, R., and Hamprecht, B. (1993) Glycogen in astrocytes, possible function as lactate supply for neighboring cells. Brain Res., 62:208-214.
10. El-Fouly, M.-H., Trosko, J.E., and Chang, C.-C. (1987) A rapid and simple technique to study gap junctional intercellular communication. Exp. Cell Res., 168:422-430.
11. Enkvist, M.O.K. and McCarthy, K.D. (1992) Activation of protein-kinase-C blocks astroglial gap junction communication and inhibits the spread of calcium waves. J. Neurochem., 59:519-526.
12. Enkvist, M.O.K. and McCarthy, K.D. (1994) Astroglial gap junction communication is increased by treatment with either glutamate or high K+ concentrations. J. Neurochem., 62:489-495.
13. Fuxe, K., Tinner, B., Staines, W., Hemsen, A., Hersh, L., and Lundberg, J. (1991) Demonstration and nature of endothelin-3-like immunoreactivity in somatostatin and choline acetyltransferase-immunoreactive nerve cells of the neostriatum of the rat. Neurosci. Lett., 123:107-111.
14. Giaume, C., Cordier, J., and Glowinski, J. (1992) Endothelins inhibit junctional permeability in cultured mouse astrocytes. Eur. J. Neurosci., 4:877-881.
15. Giaume, C., Marin, P., Cordier, J., Glowinski, J., and Premont, J. (1991) Adrenergic regulation of intercellular communications between cultured striatal astrocytes from the mouse. Proc. Natl. Acad. Sci. U.S.A., 88:5577-5581.
16. Hothersall, J.S., Baquer, N.Z., Greenbaum, A.L., and McLean, P. (1979) Alternative pathways of glucose utilization in brain: Changes in the pattern of glucose utilization in brain during development and the effect of phenazine methosulphate on the integration of metabolic routes. Arch. Biochem. Biophys., 198:478-492.
17. Hothersall, J.S., Zubariu, S., McLean, P., and Greenbaum, A.L. (1981) Alternative pathways of glucose utilization in brain: Changes in the pattern of glucose utilization in brain resulting from treatment of rats with 6-aminonicotinamide. J. Neurochem., 37:1484-1496.
18. Johnston, M.F., Simon, S.A., and Ramón, F. (1980) Interaction of anaesthetics with electrical synapses. Nature, 286:498-500.
19. Kawai, N., Yamamoto, T., Yamamoto, H., Mc Carron, R.M., and Spatz, M. (1994) Endothelin stimualtes ATPase activity in brain capillary endothelium. J. Physiol., 480:P17-P17.
20. Kettenmann, H. and Ransom, B.R. (1988) Electrical coupling between astrocytes and between oligodendrocytes studied in mammalian cell culture. Glia, 1:64-73.
21. Larrabee, M.G. (1990) Evaluation of the pentose phosphate pathway from 14CO2 data: Fallibility of a classic equation when applied to non-homogeneous tissues. Biochem. J., 272:127-132.
22. Loewenstein, W. (1981) Junctional intercellular communication: the cell-to-cell membrane channel. Physiol. Rev., 61:829-913.
23. Lowry, O.H., Rosebrough, N.J., Lewis-Farr, A., and Randall, R.J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193:265-275.
24. Mac Chamber, M.W., Ross, C.A., and Snyder, S.H (1990) Endothelin in brain: receptors, mitogenesis and biosynthesis in glial cells. Proc. Natl. Acad. Sci. U.S.A., 87:2359-2363.
25. Maher, F., Vannucci, S.J., and Simson, I.A. (1994) Glucose transporter proteins in brain. FASEB J., 8:1003-1011.
26. Mugnaini, E. (1986) Cell junctions of astrocytes, ependyma and related cells in the mammalian central nervous system, with emphasis on the hypothesis of a generalized functional syncytium of supporting cells. In: Astrocytes. S. Fedoroff and A. Vernadakis, eds. Academic Press, Inc., New York, Vol. 1, pp. 329-371.
27. Naus, C.C.G., Bechberger, J.F., Caveney, S., and Wilson, J.X. (1991) Expression of gap junction genes in astrocytes and C6 glioma cells. Neurosci. Lett., 126:33-36.
28. Pellerin, L. and Magistretti, P. (1994) Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization. Proc. Nat. Acad. Sci. U.S.A., 91:10625-10629.
29. Supattapone, S., Simpson, A.W.M., and Ashley, C.C. (1989) Free calcium rise and mitogenesis in glial cells caused by endothelin. Biochem. Biophys. Res. Comm., 165:1115-1122.
30. Swanson, R.A. and Choi, D.W. (1993) Glial glycogen stores affect neuronal survival during glucose deprivation in vitro. J. Cereb. Blood Flow Metab., 13:162-169.
31. Sykes, J.E., Lopes-Cardozo, M., and Van der Bergh, S.G. (1986) Substrate utilization for energy, production and lipid synthesis in oligodendrocyte-enriched cultures prepared from rat brain. Neurochem. Int., 8:67-75.
32. Tabernero, A., Bolaños, J.P., and Medina, J.M. (1993) Lipogenesis from lactate in rat neurons and astrocytes in primary culture. Biochem. J., 294:635-638.
33. Tabernero, A., Giaume, C., and Medina, J.M. (1994) Endothelin regulates uptake and intercellular distribution of glucose in cultured rat astrocytes. J. Physiol., 480P:20P-21P.
34. Tence, M., Cordier, J., Glowinski, J., and Premont, J. (1992) Endothelin-evoked release of arachidonic acid from mouse astrocytes in primary culture. Eur. J. Neurosci., 4:993-999.
35. Vicario, C., Tabernero, A., and Medina, J.M. (1993) Regulation of lactate metabolism by albumin in rat neurons and astrocytes from primary culture. Pediatr. Res., 34:709-715.
36. Yamamoto, T., Ochalski, A., Hertzberg, E.L., and Nagy, J.I. (1990) On the organization of astrocytic gap-junctions in rat-brain as suggested by LM-immunohistochemistry and EM-immunohistochemistry of connexin-43 expression. J. Comp. Neurol., 302:853-883.
37. Yoshimoto, S., Ishizaki, Y., Kurihara, H., Sasaki, T., Yoshizumi, M., Yanagisawa, M., Yazaki, Y., Masaki, T., Takakura, K., and Murota-S (1990) Cerebral microvessel endothelium is producing endothelin. Brain. Res., 508:283-285.
38. Yu, N., Martin, J.L., Stella, N., and Magistretti, P.J. (1993) Arachidonic acid stimulates glucose uptake in cerebral cortical astrocytes. Proc. Natl. Acad. Sci. U.S.A., 90:4022-4026.