Autocrine activation by interleukin 1α induces the fibrogenic phenotype of systemic sclerosis fibroblasts

Journal of Rheumatology

Volumn 31, Issue 10, 2004, Pages 1946-1954

  Kawaguchi, Yasushi ^a,b   McCarthy, Susan A ^a,c   Watkins, Simon C ^a   Wright, Timothy M ^a,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c NATIONAL CANCER INSTITUTE   (United States)

^d NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Fibroblasts; Fibrosis; Human skin; Interleukin 1 ; Systemic sclerosis

Indexed keywords

COMPLEMENTARY DNA; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; MESSENGER RNA; PROCOLLAGEN; THYMIDINE;

ARTICLE; AUTOCRINE EFFECT; CELL ACTIVATION; CELL FRACTIONATION; CELL PROLIFERATION; CLINICAL ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROSIS; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MOLECULAR CLONING; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN FIBROBLAST; SYSTEMIC SCLEROSIS;

AUTOCRINE COMMUNICATION; CELL PROLIFERATION; CELLS, CULTURED; FIBROBLASTS; FIBROSIS; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; OLIGONUCLEOTIDES, ANTISENSE; PHENOTYPE; PROCOLLAGEN; RNA, MESSENGER; SCLERODERMA, SYSTEMIC; SUBCELLULAR FRACTIONS;

EID: 5044232255     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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