KRAS mutation testing in human cancers: The pathologist's role in the Era of personalized medicine

Advances in Anatomic Pathology

Volumn 17, Issue 1, 2010, Pages 23-32

  Wang, Hanlin L ^a   Lopategui, Jean ^a   Amin, Mahul B ^a   Patterson, Scott D ^b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b AMGEN INC   (United States)

Author keywords

Cetuximab; Epidermal growth factor receptor; KRAS; Metastatic colorectal cancer; Panitumumab

Indexed keywords

CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; PANITUMUMAB;

CANCER GENETICS; CODON; COLORECTAL CANCER; DRUG EFFICACY; GENE MUTATION; HUMAN; MUTATIONAL ANALYSIS; ONCOGENE K RAS; PATHOLOGIST; PHYSICIAN ATTITUDE; POLYMERASE CHAIN REACTION; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; REVIEW; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

ANTIBODIES, MONOCLONAL; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; GENES, RAS; HUMANS; INDIVIDUALIZED MEDICINE; NEOPLASM METASTASIS; NEOPLASMS; PATHOLOGY, MOLECULAR; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

EID: 75449087691     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/PAP.0b013e3181c6962f     Document Type: Review

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