Sensitive detection of K-ras mutations augments diagnosis of colorectal cancer metastases in the liver

Cancer Research

Volumn 59, Issue 20, 1999, Pages 5169-5175

  Schimanski, Carl C ^a   Linnemann, Ulrich ^b   Berger, Martin R ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b Municipal Hospital Nurnberg Nord   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN;

ADULT; AGED; ARTICLE; COLORECTAL CANCER; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; ONCOGENE K RAS; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; CODON; COLORECTAL NEOPLASMS; FEMALE; GENES, RAS; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 0032725053     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Parkin, D. M., Pisani, P., and Ferlay, J. Estimates of the worldwide incidence of eighteen major cancers in 1985. Int. J Cancer, 54: 594-606, 1993.
2. Parker, S. L., Tong, T., Bolden, S., and Wingo, P. A. Cancer statistics, 1996 [see comments]. CA Cancer J. Clin., 46: 5-27, 1996.
3. Houlston, R. S., Collins, A., Slack, J., and Morton, N. E. Dominant genes for colorectal cancer are not rare. Ann. Hum. Genet., 56: 99-103, 1992.
4. Kinzler, K. W., and Vogelstein, B. Lessons from hereditary colorectal cancer. Cell, 87: 159-170, 1996.
5. Cho, K. R., and Vogelstein, B. Genetic alterations in the adenoma-carcinoma sequence. Cancer (Phila.), 70: 1727-1731, 1992.
6. Vogelstein, B., and Kinzler, K. W. The multistep nature of cancer. Trends Genet., 9: 138-141, 1993.
7. Andersen, S. N., Lovig, T., Breivik, J., Lund, E., Gaudernack, G., Meling, G. I., and Rognum, T. O. K-ras mutations and prognosis in large-bowel carcinomas. Scand. J. Gastroenterol., 32: 62-69, 1997.
8. Elnatan, J., Goh, H. S., and Smith, D. R. c-Ki-RAS activation and the biological behaviour of proximal and distal colonic adenocarcinomas. Eur. J. Cancer, 32A: 491-497, 1996.
9. Bos, J. L. ras oncogenes in human cancer: a review [published erratum appears in Cancer Res.. 50: 1352, 1990]. Cancer Res., 49: 4682-4689, 1989.
10. Konishi, M., Kikuchi-Yanoshita, R., Tanaka, K., Muraoka, M., Onda, A., Okumura, Y., Kishi, N., Iwama, T., Mon, T., Koike, M., Ushio, K., Chiba, M., Nomizu, S., Konishi, F., Utsunomiya, J., and Miyaki, M. Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer [see comments]. Gastroenterology, 111: 307-317, 1996.
11. Kahn, S. M., Jiang, W., Culbertson, T. A., Weinstein, I. B., Williams, G. M., Tomita, N., and Ronai, Z. Rapid and sensitive nonradioactive detection of mutant K-ras genes via "enriched" PCR amplification. Oncogene, 6: 1079-1083, 1991.
12. Minamoto, T., Yamashita, N., Ochiai, A., Mai, M., Sugimura, T., Ronai, Z., and Esumi, H. Mutant K-ras in apparently normal mucosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis. Cancer (Phila.), 75: 1520-1526, 1995.
13. Deuter, R., Pietsch, S., Hertel, S., and Muller, O. A method for preparation of fecal DNA suitable for PCR. Nucleic Acids Res., 23: 3800-3801, 1995.
14. Nakamori, S., Kameyama, M., Furukawa, H., Takeda, O., Sugai, S., Imaoka, S., and Nakamura, Y. Genetic detection of colorectal cancer cells in circulation and lymph nodes. Dis. Colon Rectum, 40 (Suppl.): S29-S36, 1997.
15. Weitz, J., Kienle, P., Lacroix, J., Willeke, F., Benner, A., Lehnert, T., Herfarth, C.. and von Knebel Doeberitz, M. Dissemination of tumor cells in patients undergoing surgery for colorectal cancer. Clin. Cancer Res., 4: 343-348, 1998.
16. Petrelli, N., Gupta, B., Piedmonte, M., and Herrera, L. Morbidity and survival of liver resection for colorectal adenocarcinoma [see comments]. Dis. Colon Rectum, 34: 899-904, 1991.
17. Gilbert, H. A., and Kagan, A. R. Metastases: incidence, detection, and evaluation without histologic confirmation. In: L. Weiss (ed.), Fundamental Aspects of Metastasis, pp. 385-405. Amsterdam: North-Holland, 1976.
18. Carter, R., Hemingway, D., Cooke, T. G., Pickard, R., Poon, F. W., McKillop, J. A., and McArdle, C. S. A prospective study of six methods for detection of hepatic colorectal metastases. Ann. R. Coll. Surg. Engl., 78: 27-30, 1996.
19. Vassiliades, V. G., Foley, W. D., Alarcon, J., Lawson, T., Erickson, S., Kneeland, J. B., Steinberg, H. V., and Bernardino, M. E. Hepatic metastases: CT versus MR imaging at 1.5T. Gastrointesl. Radiol., 16: 159-163, 1991.
20. Brüderlein, S., van der Bosch, K., Schlag, P., and Schwab, M. Cytogenetics and DNA amplification in colorectal cancers. Genes Chromosomes Cancer, 2: 63-70, 1990.
21. Schimanski, C. C., Sutter, C., Linnemann, U., and Berger, M. R. Sampling technique influences the detection of K-ras mutations in normal appearing mucosa of colorectal cancer patients. Int. J. Oncol., 15: 391-398, 1999.
22. Dunn, O. J. Multiple comparison using rank sums. Technometrics, 6: 241-252, 1964.
23. Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Leppert, M., Nakamura, Y., White, R., Smits, A. M., and Bos, J. L. Genetic alterations during colorectal-tumor development. N. Engl. J. Med., 319: 525-532, 1988.
24. Finkelstein, S. D., Sayegh, R., Christensen, S., and Swalsky, P. A. Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type. Cancer (Phila.), 71: 3827-3838, 1993.
25. Nelson, H. H., Christiani, D. C., Wiencke, J. K., Wain, J., Mark, E., and Kelsey, K. T. K-ras mutations and female gender in non-small cell lung cancer. Proc. Am. Assoc. Cancer Res., 40: 202, 1999.
26. Benhattar, J., Losi, L., Chaubert, P., Givel, J. C., and Costa, J. Prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology, 104: 1044-1048, 1993.
27. Minamoto, T., Esumi, H., Ochiai, A., Belitsky, G., Mai, M., Sugimura, T., and Ronai, Z. Combined analysis of microsatellite instability and K-ras mutation increases detection incidence of normal samples from colorectal cancer patients. Clin. Cancer Res., 3: 1413-1417, 1997.
28. Minamoto, T., Yamashita, N., Ochiai, A., Mai, M., Sugimura, T., Ronai, Z., and Esumi, H. Analysis of mutant K-ras in multiple sites of normal appearing mucosa of colorectal cancer patients. Int. J. Oncol., 9: 911-915, 1996.
29. Zhu, D., Keohavong, P., Finkelstein, S. D., Swalsky, P., Bakker, A., Weissfeld, J., Srivastava, S., and Whiteside, T. L. K-ras gene mutations in normal colorectal tissues from K-ras mutation-positive colorectal cancer patients. Cancer Res., 57: 2485-2492, 1997.
30. Ronai, Z., Luo, F. Q., Gradia, S., Hart, W. J., and Butler, R. Detection of K-ras mutation in normal and malignant colonic tissues by enriched PCR method. Int. J. Oncol., 4: 391-396, 1994.
31. Minamoto, T., Ronai, Z., Yamashita, N., Ochiai, A., Sugimura, T., Mai, M., and Esumi, H. Detection of Ki-ras mutation in non-neoplastic mucosa of Japanese patients with colorectal cancer. Int. J. Oncol., 4: 397-401, 1994.