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Volumn 185, Issue 2, 1998, Pages 130-138

Heterogeneity of mutant versus wild-type Ki-ras in primary and metastatic colorectal carcinomas, and association of codon-12 valine with early mortality

Author keywords

Colorectal cancer; Disease aggression; Ki ras; Metastasis; Mutation

Indexed keywords

ADULT; AGED; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; COLORECTAL CARCINOMA; CONTROLLED STUDY; GENETIC HETEROGENEITY; HUMAN; HUMAN TISSUE; LIVER METASTASIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MUTATION RATE; ONCOGENE RAS; POINT MUTATION; PRIORITY JOURNAL;

EID: 0031840930     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199806)185:2<130::AID-PATH85>3.0.CO;2-M     Document Type: Article
Times cited : (119)

References (41)
  • 3
    • 0001554828 scopus 로고
    • The classification of cancer of the rectum
    • Dukes C. The classification of cancer of the rectum. J Pathol Bacteriol 1932; 35: 323-332.
    • (1932) J Pathol Bacteriol , vol.35 , pp. 323-332
    • Dukes, C.1
  • 4
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumour development
    • Vogelstein B, Fearon E, Hamilton S, et al. Genetic alterations during colorectal-tumour development. N Engl J Med 1988; 319: 525-531.
    • (1988) N Engl J Med , vol.319 , pp. 525-531
    • Vogelstein, B.1    Fearon, E.2    Hamilton, S.3
  • 5
    • 0027196626 scopus 로고
    • Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas
    • Shibata D, Schaeffer J, Li ZH, Capella G, Perucho M. Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas. J Natl Cancer Inst 1993; 85: 1058-1063.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1058-1063
    • Shibata, D.1    Schaeffer, J.2    Li, Z.H.3    Capella, G.4    Perucho, M.5
  • 6
    • 0028361705 scopus 로고
    • c-K-ras and p53 mutations occur very early in adenocarcinoma of the lung
    • Li ZH, Zheng J, Weiss LM, Shibata D. c-K-ras and p53 mutations occur very early in adenocarcinoma of the lung. Am J Pathol 1994; 144: 303-309.
    • (1994) Am J Pathol , vol.144 , pp. 303-309
    • Li, Z.H.1    Zheng, J.2    Weiss, L.M.3    Shibata, D.4
  • 7
    • 0029987629 scopus 로고    scopus 로고
    • Intratumour heterogeneity of K-ras2 mutations in colorectal adenocarcinomas: Association with degree of DNA aneuploidy
    • Giaretti W, Monaco R, Pujic N, Rapallo A, Nigro S, Geido E. Intratumour heterogeneity of K-ras2 mutations in colorectal adenocarcinomas: association with degree of DNA aneuploidy. Am J Pathol 1996; 149: 237-245.
    • (1996) Am J Pathol , vol.149 , pp. 237-245
    • Giaretti, W.1    Monaco, R.2    Pujic, N.3    Rapallo, A.4    Nigro, S.5    Geido, E.6
  • 8
    • 0028874592 scopus 로고
    • Intratumor cellular heterogeneity and alterations in ras oncogene and p53 tumour suppressor gene in human prostatic cancer
    • Konishi N, Hiasa Y, Matsuda H, et al. Intratumor cellular heterogeneity and alterations in ras oncogene and p53 tumour suppressor gene in human prostatic cancer. Am J Pathol 1995; 147: 1112-1122.
    • (1995) Am J Pathol , vol.147 , pp. 1112-1122
    • Konishi, N.1    Hiasa, Y.2    Matsuda, H.3
  • 9
    • 0029199911 scopus 로고
    • Analysis of N-ras mutations in human cutaneous melanoma: Tumour heterogeneity detected by polymerase chain reaction/single strand conformation polymorphism analysis
    • Van Elsas A, Zerp S, van der Flier S, et al. Analysis of N-ras mutations in human cutaneous melanoma: tumour heterogeneity detected by polymerase chain reaction/single strand conformation polymorphism analysis. Recent Results Cancer Res 1995; 139: 57-67.
    • (1995) Recent Results Cancer Res , vol.139 , pp. 57-67
    • Van Elsas, A.1    Zerp, S.2    Van Der Flier, S.3
  • 10
    • 8044238349 scopus 로고    scopus 로고
    • A detailed analysis of the role of K-ras gene mutation in the progression of colorectal adenoma
    • Ohnishi T, Tomita N, Monden T, et al. A detailed analysis of the role of K-ras gene mutation in the progression of colorectal adenoma. Br J Cancer 1997; 75: 341-347.
    • (1997) Br J Cancer , vol.75 , pp. 341-347
    • Ohnishi, T.1    Tomita, N.2    Monden, T.3
  • 11
    • 0029938751 scopus 로고    scopus 로고
    • Polyclonal origin of colonic adenomas in an XO/XY patient with FAP
    • Novelli MR, Williamson JA, Tomlinson IPM, et al. Polyclonal origin of colonic adenomas in an XO/XY patient with FAP. Science 1996; 272: 1187-1190.
    • (1996) Science , vol.272 , pp. 1187-1190
    • Novelli, M.R.1    Williamson, J.A.2    Tomlinson, I.P.M.3
  • 12
    • 0027344507 scopus 로고
    • Ras-responsive genes and tumour metastasis
    • Chambers AF, Tuck AB. Ras-responsive genes and tumour metastasis. Crit Rev Oncogenesis 1993; 4: 95-114.
    • (1993) Crit Rev Oncogenesis , vol.4 , pp. 95-114
    • Chambers, A.F.1    Tuck, A.B.2
  • 14
    • 0027254425 scopus 로고
    • Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type
    • Finkelstein SD, Sayegh R, Christensen S, Swalsky PA. Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type. Cancer 1993; 71: 3827-3838.
    • (1993) Cancer , vol.71 , pp. 3827-3838
    • Finkelstein, S.D.1    Sayegh, R.2    Christensen, S.3    Swalsky, P.A.4
  • 16
    • 0029999764 scopus 로고    scopus 로고
    • Practical histological microdissection for PCR analysis
    • Going JJ, Lamb RF. Practical histological microdissection for PCR analysis. J Pathol 1996; 179: 121-124.
    • (1996) J Pathol , vol.179 , pp. 121-124
    • Going, J.J.1    Lamb, R.F.2
  • 17
    • 0030041919 scopus 로고    scopus 로고
    • Allelic imbalance at NME1 in microdissected primary and metastatic human colorectal carcinoma is frequent but not associated with metastasis to lymph-nodes or liver
    • Lamb RF, Going JJ, Pickford I, Birnie GD. Allelic imbalance at NME1 in microdissected primary and metastatic human colorectal carcinoma is frequent but not associated with metastasis to lymph-nodes or liver. Cancer Res 1996; 56: 916-920.
    • (1996) Cancer Res , vol.56 , pp. 916-920
    • Lamb, R.F.1    Going, J.J.2    Pickford, I.3    Birnie, G.D.4
  • 18
    • 0027501967 scopus 로고
    • Molecular events including p53 and k-ras alterations in the in vitro progression of a human colorectal adenoma cell line to an adenocarcinoma
    • Williams AC, Browne SJ, Yeudal W, et al. Molecular events including p53 and k-ras alterations in the in vitro progression of a human colorectal adenoma cell line to an adenocarcinoma. Oncogene 1993; 8: 3063-3072.
    • (1993) Oncogene , vol.8 , pp. 3063-3072
    • Williams, A.C.1    Browne, S.J.2    Yeudal, W.3
  • 19
    • 0022903430 scopus 로고
    • A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides
    • Vries VM, Bogaard M, Elst H, Boom J, Eb A, Bos JL. A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides. Gene 1986; 50: 313-320.
    • (1986) Gene , vol.50 , pp. 313-320
    • Vries, V.M.1    Bogaard, M.2    Elst, H.3    Boom, J.4    Eb, A.5    Bos, J.L.6
  • 21
    • 0023256456 scopus 로고
    • Prevalence of ras gene mutation in human colorectal cancer
    • Bos JL, Fearon E, Hamilton S, et al. Prevalence of ras gene mutation in human colorectal cancer. Nature 1987; 327: 293-297.
    • (1987) Nature , vol.327 , pp. 293-297
    • Bos, J.L.1    Fearon, E.2    Hamilton, S.3
  • 22
    • 0030017179 scopus 로고    scopus 로고
    • A detailed analysis of K-ras point mutations in relation to tumour progression and survival in colorectal cancer patients
    • Span M, Moerkerk PTM, Degoeij AFPM, Arends JW. A detailed analysis of K-ras point mutations in relation to tumour progression and survival in colorectal cancer patients. Int J Cancer 1996; 69: 241-245.
    • (1996) Int J Cancer , vol.69 , pp. 241-245
    • Span, M.1    Moerkerk, P.T.M.2    Degoeij, A.F.P.M.3    Arends, J.W.4
  • 23
    • 0027212026 scopus 로고
    • Prevalence to G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia
    • Urosevic N, Krtolica K, Skaro-Milic A, Knezevic-Usaj S, Dujic A. Prevalence to G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia. Int J Cancer 1993; 54: 249-254.
    • (1993) Int J Cancer , vol.54 , pp. 249-254
    • Urosevic, N.1    Krtolica, K.2    Skaro-Milic, A.3    Knezevic-Usaj, S.4    Dujic, A.5
  • 24
    • 0024376173 scopus 로고
    • ras oncogenes in human cancer: A review
    • Bos JL. ras oncogenes in human cancer: a review. Cancer Res 1989; 49: 4682-4689.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 25
    • 0030001892 scopus 로고    scopus 로고
    • Detection of DCC and Ki-ras gene alterations in colorectal carcinoma tissue as prognostic markers for liver metastasic recurrence
    • Kato M, Ito Y, Kobayashi S, Isono K. Detection of DCC and Ki-ras gene alterations in colorectal carcinoma tissue as prognostic markers for liver metastasic recurrence. Cancer 1996; 77: 1729-1735.
    • (1996) Cancer , vol.77 , pp. 1729-1735
    • Kato, M.1    Ito, Y.2    Kobayashi, S.3    Isono, K.4
  • 26
    • 0026658820 scopus 로고
    • K-ras point mutations in human colorectal carcinomas: Relation to aneuploidy and metastasis
    • Suchy B, Zietz C, Rabes HM. K-ras point mutations in human colorectal carcinomas: relation to aneuploidy and metastasis. Int J Cancer 1992; 52: 30-33.
    • (1992) Int J Cancer , vol.52 , pp. 30-33
    • Suchy, B.1    Zietz, C.2    Rabes, H.M.3
  • 27
    • 0025889018 scopus 로고
    • Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver
    • Oudejans JJ, Slebos RJC, Zoetmulder FAN, Mooi WJ, Rodenhuis S. Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver. Int J Cancer 1991; 49: 875-879.
    • (1991) Int J Cancer , vol.49 , pp. 875-879
    • Oudejans, J.J.1    Slebos, R.J.C.2    Zoetmulder, F.A.N.3    Mooi, W.J.4    Rodenhuis, S.5
  • 28
    • 0026694488 scopus 로고
    • Fate of clonal lineages during neoplasia and metastasis studied with an incorporated genetic marker
    • Moffett BF, Baban D, Bao L, et al. Fate of clonal lineages during neoplasia and metastasis studied with an incorporated genetic marker. Cancer Res 1992; 54: 1737-1743.
    • (1992) Cancer Res , vol.54 , pp. 1737-1743
    • Moffett, B.F.1    Baban, D.2    Bao, L.3
  • 29
    • 0029150669 scopus 로고
    • Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice
    • Kohl NE, Omer CA, Conner MW, et al. Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice. Nature Med 1995; 1: 792-797.
    • (1995) Nature Med , vol.1 , pp. 792-797
    • Kohl, N.E.1    Omer, C.A.2    Conner, M.W.3
  • 30
    • 0026870141 scopus 로고
    • A rapid and simple procedure for the routine detection of ras point mutations in formalin-fixed, paraffin-embedded tissues
    • Slebos RJC, Boerrigter L, Evers SG, Wisman P, Mooi JW, Rodenhuis S. A rapid and simple procedure for the routine detection of ras point mutations in formalin-fixed, paraffin-embedded tissues. Diagn Mol Pathol 1992; 1: 136-141.
    • (1992) Diagn Mol Pathol , vol.1 , pp. 136-141
    • Slebos, R.J.C.1    Boerrigter, L.2    Evers, S.G.3    Wisman, P.4    Mooi, J.W.5    Rodenhuis, S.6
  • 31
    • 0026546190 scopus 로고
    • Survival and acquired genetic alterations in colorectal cancer
    • Laurent-Puig P, Olschwang S, Delattre O, et al. Survival and acquired genetic alterations in colorectal cancer. Gastroenterology 1992; 102: 1136-1141.
    • (1992) Gastroenterology , vol.102 , pp. 1136-1141
    • Laurent-Puig, P.1    Olschwang, S.2    Delattre, O.3
  • 34
    • 25044433467 scopus 로고    scopus 로고
    • Kirsten ras mutations in 2,667 patients with colorectal cancer: Results of the RASCAL (ras collaborative) project
    • Andreyev HGN, Norman AR, Cunningham D, Oates J, Clarke PA. Kirsten ras mutations in 2,667 patients with colorectal cancer: results of the RASCAL (ras collaborative) project. Gut 1997; 40 (Suppl 1): A49.
    • (1997) Gut , vol.40 , Issue.1 SUPPL.
    • Andreyev, H.G.N.1    Norman, A.R.2    Cunningham, D.3    Oates, J.4    Clarke, P.A.5
  • 39
    • 0030929850 scopus 로고    scopus 로고
    • Uncoupling of membrane ruffling and pinocytosis during RAS signal transduction
    • Li G, D'Souza-Schorey C, Barbieri MA, Cooper JA, Stahl PD. Uncoupling of membrane ruffling and pinocytosis during RAS signal transduction. J Biol Chem 1997; 272: 10337-10340.
    • (1997) J Biol Chem , vol.272 , pp. 10337-10340
    • Li, G.1    D'Souza-Schorey, C.2    Barbieri, M.A.3    Cooper, J.A.4    Stahl, P.D.5
  • 40
    • 0029153402 scopus 로고
    • Expression of matrix metalloproteinase matrilysin (MMP-7) was induced by activated Ki-ras via AP-1 activation in SW1417 colon cancer cells
    • Yamamoto H, Itoh F, Senota A, et al. Expression of matrix metalloproteinase matrilysin (MMP-7) was induced by activated Ki-ras via AP-1 activation in SW1417 colon cancer cells. J Clin Lab Anal 1995; 9: 297-301.
    • (1995) J Clin Lab Anal , vol.9 , pp. 297-301
    • Yamamoto, H.1    Itoh, F.2    Senota, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.