-
2
-
-
44149105168
-
Molecular and cellular limits to somatosensory specificity
-
Belmonte C., and Viana F. Molecular and cellular limits to somatosensory specificity. Mol. Pain 4 (2008) 14
-
(2008)
Mol. Pain
, vol.4
, pp. 14
-
-
Belmonte, C.1
Viana, F.2
-
4
-
-
39449099998
-
The role of natural products in the ligand deorphanization of TRP channels
-
Appendino G., Minassi A., Pagani A., and Ech-Chahad A. The role of natural products in the ligand deorphanization of TRP channels. Curr. Pharm. Des. 14 (2008) 2-17
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 2-17
-
-
Appendino, G.1
Minassi, A.2
Pagani, A.3
Ech-Chahad, A.4
-
5
-
-
26444526171
-
ThermoTRP channels and cold sensing: what are they really up to?
-
Reid G. ThermoTRP channels and cold sensing: what are they really up to?. Pflugers Arch. 451 (2005) 250-263
-
(2005)
Pflugers Arch.
, vol.451
, pp. 250-263
-
-
Reid, G.1
-
7
-
-
34547953765
-
ThermoTRP channels as modular proteins with allosteric gating
-
Latorre R., Brauchi S., Orta G., Zaelzer C., and Vargas G. ThermoTRP channels as modular proteins with allosteric gating. Cell Calcium 42 (2007) 427-438
-
(2007)
Cell Calcium
, vol.42
, pp. 427-438
-
-
Latorre, R.1
Brauchi, S.2
Orta, G.3
Zaelzer, C.4
Vargas, G.5
-
8
-
-
37549029225
-
The role of the N terminus and transmembrane domain of TRPM8 in channel localization and tetramerization
-
Phelps C.B., and Gaudet R. The role of the N terminus and transmembrane domain of TRPM8 in channel localization and tetramerization. J. Biol. Chem. 282 (2007) 36474-36480
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36474-36480
-
-
Phelps, C.B.1
Gaudet, R.2
-
9
-
-
33847050898
-
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli
-
Voets T., Owsianik G., Janssens A., Talavera K., and Nilius B. TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli. Nat. Chem. Biol. 3 (2007) 174-182
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 174-182
-
-
Voets, T.1
Owsianik, G.2
Janssens, A.3
Talavera, K.4
Nilius, B.5
-
10
-
-
33645352477
-
Patapoutian, High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol A
-
Bandell M., Dubin A.E., Petrus M.J., Orth A., Mathur J., and Hwang S.W. Patapoutian, High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol A. Nat. Neurosci. 9 (2006) 493-500
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 493-500
-
-
Bandell, M.1
Dubin, A.E.2
Petrus, M.J.3
Orth, A.4
Mathur, J.5
Hwang, S.W.6
-
11
-
-
4544368241
-
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel
-
Chuang H.H., Neuhausser W.M., and Julius D. The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron 43 (2004) 859-869
-
(2004)
Neuron
, vol.43
, pp. 859-869
-
-
Chuang, H.H.1
Neuhausser, W.M.2
Julius, D.3
-
12
-
-
14844304285
-
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4
-
Nilius B., Prenen J., Janssens A., Owsianik G., Wang C., Zhu M.X., and Voets T. Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4. J. Biol. Chem. 280 (2005) 22899-22906
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 22899-22906
-
-
Nilius, B.1
Prenen, J.2
Janssens, A.3
Owsianik, G.4
Wang, C.5
Zhu, M.X.6
Voets, T.7
-
13
-
-
34948865896
-
The transmembrane segment S6 determines cation versus anion selectivity of TRPM2 and TRPM8
-
Kühn F.J., Knop G., and Lückhoff A. The transmembrane segment S6 determines cation versus anion selectivity of TRPM2 and TRPM8. J. Biol. Chem. 282 (2007) 27598-27609
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 27598-27609
-
-
Kühn, F.J.1
Knop, G.2
Lückhoff, A.3
-
14
-
-
33846011450
-
Trafficking and assembly of the cold-sensitive TRPM8 channel
-
Erler I., Al-Ansary D.M., Wissenbach U., Wagner T.F., Flockerzi V., and Niemeyer B.A. Trafficking and assembly of the cold-sensitive TRPM8 channel. J. Biol. Chem. 281 (2006) 38396-38404
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 38396-38404
-
-
Erler, I.1
Al-Ansary, D.M.2
Wissenbach, U.3
Wagner, T.F.4
Flockerzi, V.5
Niemeyer, B.A.6
-
15
-
-
34547200183
-
Dissection of the components for PIP2 activation and thermosensation in TRP channels
-
Brauchi S., Orta G., Mascayano C., Salazar M., Raddatz N., Urbina H., Rosenmann E., Gonzalez-Nilo F., and Latorre R. Dissection of the components for PIP2 activation and thermosensation in TRP channels. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 10246-10251
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 10246-10251
-
-
Brauchi, S.1
Orta, G.2
Mascayano, C.3
Salazar, M.4
Raddatz, N.5
Urbina, H.6
Rosenmann, E.7
Gonzalez-Nilo, F.8
Latorre, R.9
-
16
-
-
38549180951
-
Visualizing cold spots: TRPM8-expressing sensory neurons and their projections
-
Dhaka A., Earley T.J., Watson J., and Patapoutian A. Visualizing cold spots: TRPM8-expressing sensory neurons and their projections. J. Neurosci. 28 (2008) 566-575
-
(2008)
J. Neurosci.
, vol.28
, pp. 566-575
-
-
Dhaka, A.1
Earley, T.J.2
Watson, J.3
Patapoutian, A.4
-
17
-
-
54449099066
-
AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome
-
Lashinger E.S., Steiginga M.S., Hieble J.P., Leon L.A., Gardner S.D., Nagilla R., Davenport E.A., Hoffman B.E., Laping N.J., and Su X. AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome. Am. J. Physiol. Renal Physiol. 295 (2008) 803-810
-
(2008)
Am. J. Physiol. Renal Physiol.
, vol.295
, pp. 803-810
-
-
Lashinger, E.S.1
Steiginga, M.S.2
Hieble, J.P.3
Leon, L.A.4
Gardner, S.D.5
Nagilla, R.6
Davenport, E.A.7
Hoffman, B.E.8
Laping, N.J.9
Su, X.10
-
18
-
-
33744814084
-
Construction of human ghrelin receptor (hGHS-R1a) model using a fragmental prediction approach and validation through docking analysis
-
Pedretti A., Villa M., Pallavicini M., Valoti E., and Vistoli G. Construction of human ghrelin receptor (hGHS-R1a) model using a fragmental prediction approach and validation through docking analysis. J. Med. Chem. 49 (2006) 3077-3085
-
(2006)
J. Med. Chem.
, vol.49
, pp. 3077-3085
-
-
Pedretti, A.1
Villa, M.2
Pallavicini, M.3
Valoti, E.4
Vistoli, G.5
-
19
-
-
33947131797
-
Modeling of human ghrelin receptor (hGHS-R1a) in its close state and validation by molecular docking
-
Pedretti A., and Vistoli G. Modeling of human ghrelin receptor (hGHS-R1a) in its close state and validation by molecular docking. Bioorg. Med. Chem. 15 (2007) 3054-3064
-
(2007)
Bioorg. Med. Chem.
, vol.15
, pp. 3054-3064
-
-
Pedretti, A.1
Vistoli, G.2
-
20
-
-
40849124717
-
Fragmental modeling of human glutamate transporter EAAT1 and analysis of its binding modes by docking and pharmacophore mapping
-
Pedretti A., De Luca L., Sciarrillo C., and Vistoli G. Fragmental modeling of human glutamate transporter EAAT1 and analysis of its binding modes by docking and pharmacophore mapping. ChemMedChem 3 (2008) 79-90
-
(2008)
ChemMedChem
, vol.3
, pp. 79-90
-
-
Pedretti, A.1
De Luca, L.2
Sciarrillo, C.3
Vistoli, G.4
-
21
-
-
40849137551
-
Modelling of full-length human α4β2 nicotinic receptor by fragmental approach and analysis of its binding modes
-
Pedretti A., Marconi C., Bolchi C., Fumagalli L., Ferrara R., Pallavicini M., Valoti E., and Vistoli G. Modelling of full-length human α4β2 nicotinic receptor by fragmental approach and analysis of its binding modes. Biochem. Biophys. Res. Commun. 369 (2008) 648-653
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.369
, pp. 648-653
-
-
Pedretti, A.1
Marconi, C.2
Bolchi, C.3
Fumagalli, L.4
Ferrara, R.5
Pallavicini, M.6
Valoti, E.7
Vistoli, G.8
-
22
-
-
23244456428
-
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel
-
Long S.B., Campbell E.B., and Mackinnon R. Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science 309 (2005) 897-903
-
(2005)
Science
, vol.309
, pp. 897-903
-
-
Long, S.B.1
Campbell, E.B.2
Mackinnon, R.3
-
23
-
-
0141831003
-
Structural basis for modulation and agonist specificity of HCN pacemaker channels
-
Zagotta W.N., Olivier N.B., Black K.D., Young E.C., Olson R., and Gouaux J.E. Structural basis for modulation and agonist specificity of HCN pacemaker channels. Nature 425 (2003) 200-205
-
(2003)
Nature
, vol.425
, pp. 200-205
-
-
Zagotta, W.N.1
Olivier, N.B.2
Black, K.D.3
Young, E.C.4
Olson, R.5
Gouaux, J.E.6
-
24
-
-
34250851687
-
A local meta-threading-server for protein structure prediction
-
Wu S., and Zhang Y. A local meta-threading-server for protein structure prediction. Nucleic Acids Res. 35 (2007) 3375-3382
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 3375-3382
-
-
Wu, S.1
Zhang, Y.2
-
25
-
-
0031574072
-
The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., and Higgins D.G. The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 24 (1997) 4876-4882
-
(1997)
Nucleic Acids Res.
, vol.24
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
-
26
-
-
0036284090
-
VEGA: a versatile program to convert, handle and visualize molecular structure on Windows-based PCs
-
Pedretti A., Villa L., and Vistoli G. VEGA: a versatile program to convert, handle and visualize molecular structure on Windows-based PCs. J. Mol. Graph. 21 (2002) 47-49
-
(2002)
J. Mol. Graph.
, vol.21
, pp. 47-49
-
-
Pedretti, A.1
Villa, L.2
Vistoli, G.3
-
27
-
-
0141927229
-
Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking
-
De Luca L., Pedretti A., Vistoli G., Barreca M.L., Villa L., Monforte P., and Chimirri A. Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking. Biochem. Biophys. Res. Commun. 310 (2003) 1083-1088
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.310
, pp. 1083-1088
-
-
De Luca, L.1
Pedretti, A.2
Vistoli, G.3
Barreca, M.L.4
Villa, L.5
Monforte, P.6
Chimirri, A.7
-
28
-
-
0042415783
-
NAMD2: greater scalability for parallel molecular dynamics
-
Kalé L., Skeel R., Bhandarkar M., Brunner R., Gursoy A., Krawetz N., Phillips J., Shinozaki A., Varadarajan K., and Schulten K. NAMD2: greater scalability for parallel molecular dynamics. J. Comput. Phys. 151 (1999) 283-312
-
(1999)
J. Comput. Phys.
, vol.151
, pp. 283-312
-
-
Kalé, L.1
Skeel, R.2
Bhandarkar, M.3
Brunner, R.4
Gursoy, A.5
Krawetz, N.6
Phillips, J.7
Shinozaki, A.8
Varadarajan, K.9
Schulten, K.10
-
29
-
-
40349085541
-
Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel
-
Clayton G.M., Altieri S., Heginbotham L., Unger V.M., and Morais-Cabral J.H. Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 1511-1515
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 1511-1515
-
-
Clayton, G.M.1
Altieri, S.2
Heginbotham, L.3
Unger, V.M.4
Morais-Cabral, J.H.5
-
30
-
-
0347504835
-
TRP channels as cellular sensors
-
Clapham D.E. TRP channels as cellular sensors. Nature 426 (2003) 517-524
-
(2003)
Nature
, vol.426
, pp. 517-524
-
-
Clapham, D.E.1
-
32
-
-
0035783061
-
Protein repeats: structures, functions, and evolution
-
Andrade M.A., Perez-Iratxeta C., and Ponting C.P. Protein repeats: structures, functions, and evolution. J. Struct. Biol. 134 (2001) 117-131
-
(2001)
J. Struct. Biol.
, vol.134
, pp. 117-131
-
-
Andrade, M.A.1
Perez-Iratxeta, C.2
Ponting, C.P.3
-
33
-
-
0033587167
-
Structure of importin-beta bound to the IBB domain of importin-alpha
-
Cingolani G., Petosa C., Weis K., and Muller C.W. Structure of importin-beta bound to the IBB domain of importin-alpha. Nature 399 (1999) 221-229
-
(1999)
Nature
, vol.399
, pp. 221-229
-
-
Cingolani, G.1
Petosa, C.2
Weis, K.3
Muller, C.W.4
-
34
-
-
53849108437
-
Molecular modeling of the full-length human TRPV1 channel in closed and desensitized states
-
Fernández-Ballester G., and Ferrer-Montiel A. Molecular modeling of the full-length human TRPV1 channel in closed and desensitized states. J. Membr. Biol. 223 (2008) 161-172
-
(2008)
J. Membr. Biol.
, vol.223
, pp. 161-172
-
-
Fernández-Ballester, G.1
Ferrer-Montiel, A.2
-
35
-
-
1842453817
-
Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay
-
Behrendt H.J., Germann T., Gillen C., Hatt H., and Jostock R. Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br. J. Pharmacol. 141 (2004) 737-745
-
(2004)
Br. J. Pharmacol.
, vol.141
, pp. 737-745
-
-
Behrendt, H.J.1
Germann, T.2
Gillen, C.3
Hatt, H.4
Jostock, R.5
-
36
-
-
0037034931
-
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
-
McKemy D.D., Neuhausser W.M., and Julius D. Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416 (2002) 52-58
-
(2002)
Nature
, vol.416
, pp. 52-58
-
-
McKemy, D.D.1
Neuhausser, W.M.2
Julius, D.3
-
37
-
-
9244259076
-
Implementation and testing of stable, fast implicit solvation in molecular dynamics using the smooth-permittivity finite difference Poisson-Boltzmann method
-
Prabhu N.V., Zhu P., and Sharp K.A. Implementation and testing of stable, fast implicit solvation in molecular dynamics using the smooth-permittivity finite difference Poisson-Boltzmann method. J. Comput. Chem. 25 (2004) 2049-2064
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 2049-2064
-
-
Prabhu, N.V.1
Zhu, P.2
Sharp, K.A.3
-
38
-
-
36649016621
-
Voltage is a partial activator of rat thermosensitive TRP channels
-
Matta J.A., and Ahern G.P. Voltage is a partial activator of rat thermosensitive TRP channels. J. Physiol. 585 (2007) 469-482
-
(2007)
J. Physiol.
, vol.585
, pp. 469-482
-
-
Matta, J.A.1
Ahern, G.P.2
-
40
-
-
58149267953
-
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
-
Bocquet N., Nury H., Baaden M., Le Poupon C., Changeux J.P., Delarue M., and Corringer P.J. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature 457 (2009) 111-114
-
(2009)
Nature
, vol.457
, pp. 111-114
-
-
Bocquet, N.1
Nury, H.2
Baaden, M.3
Le Poupon, C.4
Changeux, J.P.5
Delarue, M.6
Corringer, P.J.7
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