Effects of 1α,25-dihydroxyvitamin D3 on transporters and enzymes of the rat intestine and kidney in vivo

Biopharmaceutics and Drug Disposition

Volumn 31, Issue 1, 2010, Pages 91-108

  Chow, Edwin C Y ^a   Sun, Huadong ^a   Khan, Ansar A ^b   Groothuis, Geny M M ^b   Pang, K Sandy ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

1 ,25 dihydroxyvitamin D3; Asbt; Colon; Cyp24 and Cyp3a9; Cytochrome P450 enzymes; Enzymes; Intestine; Kidney; Mdr1a; Mrp; Nuclear receptors; Oat; P gp; PepT1; Transporters; Vitamin D receptor

Indexed keywords

CALCITRIOL; CELL NUCLEUS RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 3A; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; CYTOCHROME P450 3A9; GLYCOPROTEIN P; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 3; PEPTIDE TRANSPORTER 1; PEPTIDE TRANSPORTER 2; PROTEIN TYROSINE PHOSPHATASE SHP; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; CARRIER PROTEIN; DIHYDROXY VITAMIN D3; DIHYDROXY-VITAMIN D3; DRUG DERIVATIVE; VITAMIN D;

ANIMAL EXPERIMENT; ARTICLE; COLON; DRUG DISPOSITION; DRUG EFFECT; DRUG TARGETING; DUODENUM; ENZYME LOCALIZATION; IN VIVO STUDY; JEJUNUM; KIDNEY; LIVER; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SMALL INTESTINE; ANIMAL; HUMAN; INTESTINE; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; HUMANS; INTESTINES; KIDNEY; LIVER; MALE; MEMBRANE TRANSPORT PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; VITAMIN D;

EID: 75349093233     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.694     Document Type: Article

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