Up-regulation of transporters and enzymes by the vitamin D receptor ligands, 1α,25-dihydroxyvitamin D3 and vitamin D analogs, in the caco-2 cell monolayer

Journal of Pharmacology and Experimental Therapeutics

Volumn 330, Issue 2, 2009, Pages 389-402

  Fan, Jianghong ^a   Liu, Shanjun ^a   Du, Yimin ^a   Morrison, Jodi ^b   Shipman, Robert ^b   Pang, K Sandy ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b NoAb BioDiscoveries Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALFACALCIDOL; CALCIFEDIOL; CALCITRIOL; CARRIER PROTEIN; CYTOCHROME P450 3A4; DOXERCALCIFEROL; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; PEPTIDE TRANSPORTER 1; SODIUM DEPENDENT BILE ACID TRANSPORTER; SULFOTRANSFERASE; SULFOTRANSFERASE 1E1; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; MONOLAYER CULTURE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR INTRINSIC ACTIVITY; UPREGULATION;

CACO-2 CELLS; CYTOCHROME P-450 CYP3A; GENE EXPRESSION PROFILING; HUMANS; LIGANDS; MEMBRANE TRANSPORT PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, CALCITRIOL; UP-REGULATION; VITAMIN D;

EID: 67651039735     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.149815     Document Type: Article

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