Predicting functional alternative splicing by measuring RNA selection pressure from multigenome alignments

PLoS Computational Biology

Volumn 5, Issue 12, 2009, Pages

  Lu, Hongchao ^a   Lin, Lan ^b   Sato, Seiko ^b   Xing, Yi ^b,c   Lee, Christopher J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c IA United States   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FORECASTING; GENES; TISSUE;

ALTERNATIVE SPLICING; EVOLUTIONARY SELECTION; GENOME ALIGNMENT; HIGH-THROUGHPUT METHOD; PREDICTIVE POWER; PRESSURE RATIO; PROTEIN SEQUENCES; SELECTION PRESSURES; TISSUE-SPECIFIC REGULATION; VERTEBRATE GENOMES;

RNA;

MESSENGER RNA; CARRIER PROTEIN; EXOC7 PROTEIN, MOUSE; GPRIN1 PROTEIN, MOUSE; GRIN1 PROTEIN, HUMAN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NERVE PROTEIN; RNA; VESICULAR TRANSPORT PROTEIN;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; EXOC7 GENE; EXON; GENE; GRIN1 GENE; HUMAN; MOUSE; NONHUMAN; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; DNA MICROARRAY; EXPRESSED SEQUENCE TAG; GENETICS; GENOME; METHODOLOGY; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT;

VERTEBRATA;

ALTERNATIVE SPLICING; ANIMALS; CARRIER PROTEINS; COMPUTATIONAL BIOLOGY; EXPRESSED SEQUENCE TAGS; GENOME; HUMANS; MICE; MODELS, GENETIC; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, N-METHYL-D-ASPARTATE; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SEQUENCE ALIGNMENT; VESICULAR TRANSPORT PROTEINS;

EID: 74549226523     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000608     Document Type: Article

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