A genomic view of alternative splicing

Nature Genetics

Volumn 30, Issue 1, 2002, Pages 13-19

  Modrek, Barmak ^a   Lee, Christopher ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

ALTERNATIVE RNA SPLICING; APOPTOSIS; BIOINFORMATICS; EXPRESSED SEQUENCE TAG; GENOMICS; HUMAN; HUMAN GENOME; PRIORITY JOURNAL; RELIABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW;

ALTERNATIVE SPLICING; ANIMALS; COMPUTATIONAL BIOLOGY; DNA; EXPRESSED SEQUENCE TAGS; FALSE POSITIVE REACTIONS; FORECASTING; GENOMICS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN ISOFORMS; RNA, MESSENGER; VARIATION (GENETICS);

EID: 0036337915     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng0102-13     Document Type: Review

References (39)

1. Human genome project: And the gene number is...?
2. The genome sequence of Drosophila melanogaster
3. Genome sequence of the nematode C. elegans: A platform for investigating biology
4. Initial sequencing and analysis of the human genome
5. The sequence of the human genome
6. Adenovirus amazes at Cold Spring Harbor
7. Why genes in pieces?
8. Two mRNAs can be produced from a single immunoglobulin m gene by alternative RNA processing pathways
9. Calcitonin mRNA polymorphism: Peptide switching associated with alternative RNA splicing events
10. Split genes and RNA splicing
11. Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation
12. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
13. Alternative pre-mRNA splicing: The logic of combinatorial control
14. Frequent alternative splicing of human genes
15. ISIS, the intron information system, reveals the high frequency of alternative splicing in the human genome
16. EST comparison indicates 38% of human mRNAs contain possible alternative splice forms
17. Gene structure prediction and alternative splicing analysis using genomically aligned ESTs
18. Genome-wide analysis of alternative splicing using human expressed sequence data
19. Analysis of canonical and non-canonical splice sites in mammalian genomes
20. Patterns of variant polyadenylation signal usage in human genes
21. Alternative splicing: Increasing diversity in the proteomic world
22. Database resources of the National Center for Biotechnology Information
23. Alternative gene form discovery and candidate gene selection from gene indexing projects
24. Experimental annotation of the human genome using microarray technology
25. Predicting splice variant from DNA chip expression data
26. The mutational spectrum of single basepair substitutions in mRNA splice junctions of human genes: Causes and consequences
27. A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes
28. A sequence compilation and comparison of exons that are alternatively spliced in neurons
29. Conservation, regulation, synteny, and introns in a large-scale C. briggsae-C. elegans genomic alignment
30. An alternative-exon database and its statistical analysis
31. Computational analysis of candidate intron regulatory elements for tissue-specific alternative pre-mRNA splicing
32. A complex intronic splicing enhancer from the c-src pre-mRNA activates inclusion of a heterologous exon
33. Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element
34. Control of alternative pre-mRNA splicing by distributed pentameric repeats
35. Neuron-specific alternative splicing of nonmuscle myosin II heavy chain-B pre-mRNA requires a cis-acting intron sequence
36. ASDB database of alternatively spliced genes
37. AsMamDB: An alternative splice database of mammals
38. Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cervisiae
39. The intronerator: Exploring introns and alternative splicing in Caenorhabditis elegans