Opposite evolutionary effects between different alternative splicing patterns

Molecular Biology and Evolution

Volumn 24, Issue 7, 2007, Pages 1443-1446

  Chen, Feng Chi ^a   Chaw, Shu Miaw ^b   Tzeng, Yun Huei ^c   Wang, Sheng Shun ^c   Chuang, Trees Juen ^c  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b BIODIVERSITY RESEARCH CENTER   (Taiwan)

^c GENOMICS RESEARCH CENTER   (Taiwan)

Author keywords

Comparative genomics; Complex alternatively spliced exons; Constitutively spliced exons; Lineage specificity; Selective constraint; Simple alternatively spliced exons

Indexed keywords

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ARTICLE; EVOLUTION; EVOLUTIONARY RATE; EXON; GENETIC LINKAGE; GENOMICS;

ALTERNATIVE SPLICING; ANIMALS; EVOLUTION, MOLECULAR; EXONS; HUMANS; MICE; SELECTION (GENETICS);

EID: 34547657299     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msm072     Document Type: Article

References (15)

1. Bracco L, Kearsey J. 2003. The relevance of alternative RNA splicing to pharmacogenomics. Trends Biotechnol. 21:346-353.
2. Brett D, Pospisil H, Valcarcel J, Reich J, Bork P. 2002. Alternative splicing and genome complexity. Nat Genet. 30:29-30.
3. Chen FC, Chuang TJ. 2006. The effects of multiple features of alternatively spliced exons on the Ka/Ks ratio test. BMC Bioinformatics. 7:259.
4. Chen FC, Wang SS, Chen CJ, Li WH, Chuang TJ. 2006. Alternatively and constitutively spliced exons are subject to different evolutionary forces. Mol Biol Evol. 23:675-682.
5. Filip LC, Mundy NI. 2004. Rapid evolution by positive Darwinian selection in the extracellular domain of the abundant lymphocyte protein CD45 in primates. Mol Biol Evol. 21:1504-1511.
6. Gene Ontology Consortium. 2001. Creating the gene ontology resource: design and implementation. Genome Res. 11:1425-1433.
7. Hurst LD, Pal C. 2001. Evidence for purifying selection acting on silent sites in BRCA1. Trends Genet. 17:62-65.
8. Iida K, Akashi H. 2000. A test of translational selection at 'silent' sites in the human genome: base composition comparisons in alternatively spliced genes. Gene. 261:93-105.
9. Li W-H. 1997. Molecular evolution. Sunderland (MA): Sinauer Associates.
10. Modrek B, Lee CJ. 2003. Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss. Nat Genet. 34:177-180.
11. Nekrutenko A, Chung WY, Li WH. 2003. An evolutionary approach reveals a high protein-coding capacity of the human genome. Trends Genet. 19:306-310.
12. Rozas J, Sanchez-DelBarrio JC, Messeguer X, Rozas R. 2003. DnaSP, DNA polymorphism analyses by the coalescent and other methods. Bioinformatics. 19:2496-2497.
13. Stamm S, Riethoven JJ, Le Texier V, Gopalakrishnan C, Kumanduri V, Tang Y, Barbosa-Morais NL, Thanaraj TA. 2006. ASD: a bioinformatics resource on alternative splicing. Nucleic Acids Res. 34:D46-D55.
14. Xing Y, Lee C. 2005. Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences. Proc Natl Acad Sci USA. 102:13526-13531.
15. Yang Z, Nielsen R. 2000. Estimating synonymous and nonsynonymous substitution rates under realistic evolutionary models. Mol Biol Evol. 17:32-43.