Ibuprofen-induced Walker 256 tumor cell death: Cytochrome c release from functional mitochondria and enhancement by calcineurin inhibition

Biochemical Pharmacology

Volumn 68, Issue 11, 2004, Pages 2197-2206

  Campos, Claudia B L ^a   Degasperi, Giovanna R ^a   Pacífico, Denise S ^a   Alberici, Luciane C ^a   Carreira, Raquel S ^b   Guimarães, Fernando ^a   Castilho, Roger F ^a   Vercesi, Anibal E ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Apoptosis; Calcineurin; Cytochrome c; Electrical transmembrane potential; Ibuprofen; Mitochondrion

Indexed keywords

ADENOSINE TRIPHOSPHATE; BONGKREKIC ACID; CALCINEURIN; CALCINEURIN INHIBITOR; CYCLOSPORIN A; CYTOCHROME C; IBUPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT; OLIGOMYCIN; STAUROSPORINE; TACROLIMUS;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CONTROLLED STUDY; DEPOLARIZATION; FLOW CYTOMETRY; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; WALKER CARCINOMA;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALCINEURIN; CELL DEATH; CYCLOSPORINE; CYTOCHROMES C; HYDROLYSIS; IBUPROFEN; ION CHANNELS; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; RATS; RESPIRATION; TACROLIMUS; TUMOR CELLS, CULTURED;

EID: 7444225747     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.08.006     Document Type: Article

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