Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons

Brain Research

Volumn 857, Issue 1-2, 2000, Pages 20-29

  Petersén, Åsa ^a   Castilho, Roger F ^a   Hansson, Oskar ^a   Wieloch, Tadeusz ^a   Brundin, Patrik ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Apoptosis; Calcium; Cell death; Huntington's disease; Mitochondria; Striatal neuron

Indexed keywords

ACETYLASPARTYLGLUTAMYLVALYLASPARTALDEHYDE; ACETYLTYROSYLVALYLALANYLASPARTALDEHYDE; ANTIOXIDANT; CALCIMYCIN; CASPASE; CASPASE INHIBITOR; CYCLOSPORIN A; CYCLOSPORIN A [4 N METHYLVALINE]; CYCLOSPORIN A DERIVATIVE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN; PORPHYRIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CONTROLLED STUDY; CORPUS STRIATUM; DOSE TIME EFFECT RELATION; EMBRYO; ENZYME ACTIVITY; IN VITRO STUDY; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NECROSIS; NERVE CELL CULTURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; CALCIMYCIN; CALCIUM; CALCIUM METABOLISM DISORDERS; CASPASES; CELL CULTURE TECHNIQUES; CELL DEATH; CELL MEMBRANE PERMEABILITY; CORPUS STRIATUM; CYCLOSPORINE; CYSTEINE PROTEINASE INHIBITORS; EMBRYO; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; IONOPHORES; METALLOPORPHYRINS; MITOCHONDRIAL SWELLING; NEURONS; OLIGOPEPTIDES; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 0033975779     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02320-3     Document Type: Article

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