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Volumn 23, Issue 1, 2010, Pages 41-56

Dormancy of metastatic melanoma

Author keywords

B Raf N Ras; GNAQ; Micrometastasis; Residual disease

Indexed keywords

B RAF KINASE; FIBRILLAR COLLAGEN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; TRANSFORMING GROWTH FACTOR BETA;

EID: 74349102988     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2009.00647.x     Document Type: Review
Times cited : (109)

References (162)
  • 1
    • 55749089875 scopus 로고    scopus 로고
    • Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
    • Aasen, T., Raya, A., Barrero, M.J. et al. (2008). Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat. Biotechnol. 26, 1276 1284.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1276-1284
    • Aasen, T.1    Raya, A.2    Barrero, M.J.3
  • 2
    • 0037061762 scopus 로고    scopus 로고
    • Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo
    • Aguirre Ghiso, J.A. (2002). Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo. Oncogene 21, 2513 2524.
    • (2002) Oncogene , vol.21 , pp. 2513-2524
    • Aguirre Ghiso, J.A.1
  • 3
    • 0002460807 scopus 로고    scopus 로고
    • Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling
    • Aguirre Ghiso, J.A., Kovalski, K. Ossowski, L. (1999). Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling. J. Cell Biol. 147, 89 104.
    • (1999) J. Cell Biol. , vol.147 , pp. 89-104
    • Aguirre Ghiso, J.A.1    Kovalski, K.2    Ossowski, L.3
  • 4
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • Aguirre-Ghiso, J.A. (2007). Models, mechanisms and clinical evidence for cancer dormancy. Nat. Rev. Cancer 7, 834 846.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 5
    • 0037379794 scopus 로고    scopus 로고
    • ERK(MAPK) activity as a determinant of tumor growth and dormancy; Regulation by p38(SAPK)
    • Aguirre-Ghiso, J.A., Estrada, Y., Liu, D. Ossowski, L. (2003). ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK). Cancer Res. 63, 1684 1695.
    • (2003) Cancer Res. , vol.63 , pp. 1684-1695
    • Aguirre-Ghiso, J.A.1    Estrada, Y.2    Liu, D.3    Ossowski, L.4
  • 6
    • 68349099107 scopus 로고    scopus 로고
    • Number crunching in the cancer stem cell market
    • Alison, M.R., Islam, S. Lim, S.M. (2009). Number crunching in the cancer stem cell market. Breast Cancer Res. 11, 302.
    • (2009) Breast Cancer Res. , vol.11 , pp. 302
    • Alison, M.R.1    Islam, S.2    Lim, S.M.3
  • 7
    • 44349105402 scopus 로고    scopus 로고
    • Early detection of melanoma progression by quantitative real-time RT-PCR analysis for multiple melanoma markers
    • Arenberger, P., Arenbergerova, M., Vohradnikova, O. Kremen, J. (2008). Early detection of melanoma progression by quantitative real-time RT-PCR analysis for multiple melanoma markers. Keio J. Med. 57, 57 64.
    • (2008) Keio J. Med. , vol.57 , pp. 57-64
    • Arenberger, P.1    Arenbergerova, M.2    Vohradnikova, O.3    Kremen, J.4
  • 9
    • 33750306612 scopus 로고    scopus 로고
    • Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
    • Balic, M., Lin, H., Young, L., Hawes, D., Giuliano, A., Mcnamara, G., Datar, R.H. Cote, R.J. (2006). Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin. Cancer Res. 12, 5615 5621.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 5615-5621
    • Balic, M.1    Lin, H.2    Young, L.3    Hawes, D.4    Giuliano, A.5    McNamara, G.6    Datar, R.H.7    Cote, R.J.8
  • 10
    • 0031929106 scopus 로고    scopus 로고
    • Tumor vascularity, proliferation, and apoptosis in human melanoma micrometastases and macrometastases
    • Barnhill, R.L., Piepkorn, M.W., Cochran, A.J., Flynn, E., Karaoli, T. Folkman, J. (1998). Tumor vascularity, proliferation, and apoptosis in human melanoma micrometastases and macrometastases. Arch. Dermatol. 134, 991 994.
    • (1998) Arch. Dermatol. , vol.134 , pp. 991-994
    • Barnhill, R.L.1    Piepkorn, M.W.2    Cochran, A.J.3    Flynn, E.4    Karaoli, T.5    Folkman, J.6
  • 11
    • 70249134535 scopus 로고    scopus 로고
    • Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma
    • Bauer, J., Kilic, E., Vaarwater, J., Bastian, B.C., Garbe, C. De Klein, A. (2009). Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma. Br. J. Cancer 101, 813 815.
    • (2009) Br. J. Cancer , vol.101 , pp. 813-815
    • Bauer, J.1    Kilic, E.2    Vaarwater, J.3    Bastian, B.C.4    Garbe, C.5    De Klein, A.6
  • 13
    • 33747866678 scopus 로고    scopus 로고
    • Transcriptional regulation of human MAP2 gene in melanoma: Role of neuronal bHLH factors and Notch1 signaling
    • Bhat, K.M., Maddodi, N., Shashikant, C. Setaluri, V. (2006). Transcriptional regulation of human MAP2 gene in melanoma: role of neuronal bHLH factors and Notch1 signaling. Nucleic Acids Res. 34, 3819 3832.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 3819-3832
    • Bhat, K.M.1    Maddodi, N.2    Shashikant, C.3    Setaluri, V.4
  • 15
    • 0034086867 scopus 로고    scopus 로고
    • Mutation and allelic loss of the PTEN/MMAC1 gene in primary and metastatic melanoma biopsies
    • Birck, A., Ahrenkiel, V., Zeuthen, J., Hou-Jensen, K. Guldberg, P. (2000). Mutation and allelic loss of the PTEN/MMAC1 gene in primary and metastatic melanoma biopsies. J. Invest. Dermatol. 114, 277 280.
    • (2000) J. Invest. Dermatol. , vol.114 , pp. 277-280
    • Birck, A.1    Ahrenkiel, V.2    Zeuthen, J.3    Hou-Jensen, K.4    Guldberg, P.5
  • 16
    • 33746911580 scopus 로고    scopus 로고
    • B-RAF and PI-3 kinase signaling protect melanoma cells from anoikis
    • Boisvert-Adamo, K. Aplin, A.E. (2006). B-RAF and PI-3 kinase signaling protect melanoma cells from anoikis. Oncogene 25, 4848 4856.
    • (2006) Oncogene , vol.25 , pp. 4848-4856
    • Boisvert-Adamo, K.1    Aplin, A.E.2
  • 18
    • 34250318212 scopus 로고    scopus 로고
    • Identification of circulating malignant cells and its correlation with prognostic factors and treatment in uveal melanoma. A prospective longitudinal study
    • Callejo, S.A., Antecka, E., Blanco, P.L., Edelstein, C. Burnier, M.N. Jr. (2007). Identification of circulating malignant cells and its correlation with prognostic factors and treatment in uveal melanoma. A prospective longitudinal study. Eye 21, 752 759.
    • (2007) Eye , vol.21 , pp. 752-759
    • Callejo, S.A.1    Antecka, E.2    Blanco, P.L.3    Edelstein, C.4    Burnier, Jr.M.N.5
  • 20
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • Chambers, A.F., Groom, A.C. Macdonald, I.C. (2002). Dissemination and growth of cancer cells in metastatic sites. Nat. Rev. Cancer 2, 563 572.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    MacDonald, I.C.3
  • 21
    • 0141483383 scopus 로고    scopus 로고
    • Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells
    • Conner, S.R., Scott, G. Aplin, A.E. (2003). Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells. J. Biol. Chem. 278, 34548 34554.
    • (2003) J. Biol. Chem. , vol.278 , pp. 34548-34554
    • Conner, S.R.1    Scott, G.2    Aplin, A.E.3
  • 22
    • 0025351868 scopus 로고
    • Late recurrence of malignant melanoma. Analysis of 168 patients
    • Crowley, N.J. Seigler, H.F. (1990a). Late recurrence of malignant melanoma. Analysis of 168 patients. Ann. Surg. 212, 173 177.
    • (1990) Ann. Surg. , vol.212 , pp. 173-177
    • Crowley, N.J.1    Seigler, H.F.2
  • 23
    • 0025676477 scopus 로고
    • The role of elective lymph node dissection in the management of patients with thick cutaneous melanoma
    • Crowley, N.J. Seigler, H.F. (1990b). The role of elective lymph node dissection in the management of patients with thick cutaneous melanoma. Cancer 66, 2522 2527.
    • (1990) Cancer , vol.66 , pp. 2522-2527
    • Crowley, N.J.1    Seigler, H.F.2
  • 24
    • 36549085004 scopus 로고    scopus 로고
    • The genome and epigenome of malignant melanoma
    • Dahl, C. Guldberg, P. (2007). The genome and epigenome of malignant melanoma. APMIS 115, 1161 1176.
    • (2007) APMIS , vol.115 , pp. 1161-1176
    • Dahl, C.1    Guldberg, P.2
  • 25
    • 14944352371 scopus 로고    scopus 로고
    • Prognostic significance of activated Akt expression in melanoma: A clinicopathologic study of 292 cases
    • Dai, D.L., Martinka, M. Li, G. (2005). Prognostic significance of activated Akt expression in melanoma: a clinicopathologic study of 292 cases. J. Clin. Oncol. 23, 1473 1482.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 1473-1482
    • Dai, D.L.1    Martinka, M.2    Li, G.3
  • 27
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies, H., Bignell, G.R., Cox, C. et al. (2002). Mutations of the BRAF gene in human cancer. Nature 417, 949 954.
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1    Bignell, G.R.2    Cox, C.3
  • 28
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean, M., Fojo, T. Bates, S. (2005). Tumour stem cells and drug resistance. Nat. Rev. Cancer 5, 275 284.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 29
    • 58149239731 scopus 로고    scopus 로고
    • Ski and SnoN, potent negative regulators of TGF-beta signaling
    • Deheuninck, J. Luo, K. (2009). Ski and SnoN, potent negative regulators of TGF-beta signaling. Cell Res. 19, 47 57.
    • (2009) Cell Res. , vol.19 , pp. 47-57
    • Deheuninck, J.1    Luo, K.2
  • 30
    • 0034865262 scopus 로고    scopus 로고
    • Tumour dormancy: Findings and hypotheses from clinical research on breast cancer
    • Demicheli, R. (2001). Tumour dormancy: findings and hypotheses from clinical research on breast cancer. Semin. Cancer Biol. 11, 297 306.
    • (2001) Semin. Cancer Biol. , vol.11 , pp. 297-306
    • Demicheli, R.1
  • 31
    • 65949118505 scopus 로고    scopus 로고
    • Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species
    • Deng, X., Ewton, D.Z. Friedman, E. (2009). Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species. Cancer Res. 69, 3317 3324.
    • (2009) Cancer Res. , vol.69 , pp. 3317-3324
    • Deng, X.1    Ewton, D.Z.2    Friedman, E.3
  • 32
    • 33749184798 scopus 로고    scopus 로고
    • Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway
    • Denoyelle, C., Abou-Rjaily, G., Bezrookove, V. et al. (2006). Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. Nat. Cell Biol. 8, 1053 1063.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1053-1063
    • Denoyelle, C.1    Abou-Rjaily, G.2    Bezrookove, V.3
  • 33
    • 65649090993 scopus 로고    scopus 로고
    • BRAF signaling and targeted therapies in melanoma
    • ix
    • Dhomen, N. Marais, R. (2009). BRAF signaling and targeted therapies in melanoma. Hematol. Oncol. Clin. North Am. 23, 529 545, ix.
    • (2009) Hematol. Oncol. Clin. North Am. , vol.23 , pp. 529-545
    • Dhomen, N.1    Marais, R.2
  • 35
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • Dimos, J.T., Rodolfa, K.T., Niakan, K.K. et al. (2008). Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 321, 1218 1221.
    • (2008) Science , vol.321 , pp. 1218-1221
    • Dimos, J.T.1    Rodolfa, K.T.2    Niakan, K.K.3
  • 36
    • 0034040637 scopus 로고    scopus 로고
    • P21(cip1) mRNA is controlled by endogenous transforming growth factor-beta1 in quiescent human hematopoietic stem/progenitor cells
    • Ducos, K., Panterne, B., Fortunel, N., Hatzfeld, A., Monier, M.N. Hatzfeld, J. (2000). p21(cip1) mRNA is controlled by endogenous transforming growth factor-beta1 in quiescent human hematopoietic stem/progenitor cells. J. Cell. Physiol. 184, 80 85.
    • (2000) J. Cell. Physiol. , vol.184 , pp. 80-85
    • Ducos, K.1    Panterne, B.2    Fortunel, N.3    Hatzfeld, A.4    Monier, M.N.5    Hatzfeld, J.6
  • 37
    • 39149137539 scopus 로고    scopus 로고
    • Spontaneous regression of cutaneous head and neck melanoma: Implications for the immunologic control of neoplasia
    • Dunn, G.P., Lewis, J.S. Jr., Sunwoo, J.B. Uppaluri, R. (2008). Spontaneous regression of cutaneous head and neck melanoma: implications for the immunologic control of neoplasia. Head Neck 30, 267 272.
    • (2008) Head Neck , vol.30 , pp. 267-272
    • Dunn, G.P.1    Lewis, Jr.J.S.2    Sunwoo, J.B.3    Uppaluri, R.4
  • 38
    • 0033769530 scopus 로고    scopus 로고
    • Tumor doubling times in metastatic malignant melanoma of the uvea: Tumor progression before and after treatment
    • Eskelin, S., Pyrhonen, S., Summanen, P., Hahka-Kemppinen, M. Kivela, T. (2000). Tumor doubling times in metastatic malignant melanoma of the uvea: tumor progression before and after treatment. Ophthalmology 107, 1443 1449.
    • (2000) Ophthalmology , vol.107 , pp. 1443-1449
    • Eskelin, S.1    Pyrhonen, S.2    Summanen, P.3    Hahka-Kemppinen, M.4    Kivela, T.5
  • 39
    • 58649115386 scopus 로고    scopus 로고
    • Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation
    • Estrada, Y., Dong, J. Ossowski, L. (2009). Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation. Pigment Cell Melanoma Res. 22, 66 76.
    • (2009) Pigment Cell Melanoma Res. , vol.22 , pp. 66-76
    • Estrada, Y.1    Dong, J.2    Ossowski, L.3
  • 41
    • 44849137232 scopus 로고    scopus 로고
    • Oncogene addiction versus oncogene amnesia: Perhaps more than just a bad habit?
    • discussion 3086
    • Felsher, D.W. (2008a). Oncogene addiction versus oncogene amnesia: perhaps more than just a bad habit? Cancer Res. 68, 3081 3086 discussion 3086.
    • (2008) Cancer Res. , vol.68 , pp. 3081-3086
    • Felsher, D.W.1
  • 42
    • 52049122139 scopus 로고    scopus 로고
    • Tumor dormancy and oncogene addiction
    • Felsher, D.W. (2008b). Tumor dormancy and oncogene addiction. APMIS 116, 629 637.
    • (2008) APMIS , vol.116 , pp. 629-637
    • Felsher, D.W.1
  • 43
    • 34547883142 scopus 로고    scopus 로고
    • Dermatopathological indicators of poor melanoma prognosis are significantly inversely correlated with the expression of NM23 protein in primary cutaneous melanoma
    • Ferrari, D., Lombardi, M., Ricci, R., Michiara, M., Santini, M. De Panfilis, G. (2007). Dermatopathological indicators of poor melanoma prognosis are significantly inversely correlated with the expression of NM23 protein in primary cutaneous melanoma. J. Cutan. Pathol. 34, 705 712.
    • (2007) J. Cutan. Pathol. , vol.34 , pp. 705-712
    • Ferrari, D.1    Lombardi, M.2    Ricci, R.3    Michiara, M.4    Santini, M.5    De Panfilis, G.6
  • 44
    • 0020900392 scopus 로고
    • The ernst W. Bertner memorial award lecture: The evolution of biological heterogeneity in metastatic neoplasms
    • Fidler, I.J. (1983). The Ernst W. Bertner Memorial Award lecture: the evolution of biological heterogeneity in metastatic neoplasms. Symp. Fundam. Cancer Res. 36, 5 26.
    • (1983) Symp. Fundam. Cancer Res. , vol.36 , pp. 5-26
    • Fidler, I.J.1
  • 45
    • 33947095629 scopus 로고    scopus 로고
    • Human tumor antigens, immunosurveillance, and cancer vaccines
    • Finn, O.J. (2006). Human tumor antigens, immunosurveillance, and cancer vaccines. Immunol. Res. 36, 73 82.
    • (2006) Immunol. Res. , vol.36 , pp. 73-82
    • Finn, O.J.1
  • 46
    • 0000945739 scopus 로고
    • Experimental evidence in support of the dormant tumor cell
    • Fisher, B. Fisher, E.R. (1959). Experimental evidence in support of the dormant tumor cell. Science 130, 918 919.
    • (1959) Science , vol.130 , pp. 918-919
    • Fisher, B.1    Fisher, E.R.2
  • 47
    • 0030457645 scopus 로고    scopus 로고
    • TGF-beta mediated G1 arrest in a human melanoma cell line lacking p15INK4B: Evidence for cooperation between p21Cip1/WAF1 and p27Kip1
    • Florenes, V.A., Bhattacharya, N., Bani, M.R., Ben-David, Y., Kerbel, R.S. Slingerland, J.M. (1996). TGF-beta mediated G1 arrest in a human melanoma cell line lacking p15INK4B: evidence for cooperation between p21Cip1/WAF1 and p27Kip1. Oncogene 13, 2447 2457.
    • (1996) Oncogene , vol.13 , pp. 2447-2457
    • Florenes, V.A.1    Bhattacharya, N.2    Bani, M.R.3    Ben-David, Y.4    Kerbel, R.S.5    Slingerland, J.M.6
  • 48
    • 0000204925 scopus 로고
    • Tumor progression
    • Foulds, L. (1957). Tumor progression. Cancer Res. 17, 355 356.
    • (1957) Cancer Res. , vol.17 , pp. 355-356
    • Foulds, L.1
  • 50
    • 33646271857 scopus 로고    scopus 로고
    • Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment
    • Gajewski, T.F. (2006). Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment. Clin. Cancer Res. 12, 2326s 2330s.
    • (2006) Clin. Cancer Res. , vol.12
    • Gajewski, T.F.1
  • 51
    • 0037105557 scopus 로고    scopus 로고
    • The long-term clinical course of patients with cutaneous melanoma
    • Gamel, J.W., George, S.L., Edwards, M.J. Seigler, H.F. (2002). The long-term clinical course of patients with cutaneous melanoma. Cancer 95, 1286 1293.
    • (2002) Cancer , vol.95 , pp. 1286-1293
    • Gamel, J.W.1    George, S.L.2    Edwards, M.J.3    Seigler, H.F.4
  • 52
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • Gottesman, M.M. (2002). Mechanisms of cancer drug resistance. Annu. Rev. Med. 53, 615 627.
    • (2002) Annu. Rev. Med. , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 53
    • 51749102145 scopus 로고    scopus 로고
    • Melanoma, nevogenesis, and stem cell biology
    • Grichnik, J.M. (2008). Melanoma, nevogenesis, and stem cell biology. J. Invest. Dermatol. 128, 2365 2380.
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 2365-2380
    • Grichnik, J.M.1
  • 54
    • 0030777104 scopus 로고    scopus 로고
    • Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma
    • Guldberg, P., Thor Straten, P., Birck, A., Ahrenkiel, V., Kirkin, A.F. Zeuthen, J. (1997). Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res. 57, 3660 3663.
    • (1997) Cancer Res. , vol.57 , pp. 3660-3663
    • Guldberg, P.1    Thor Straten, P.2    Birck, A.3    Ahrenkiel, V.4    Kirkin, A.F.5    Zeuthen, J.6
  • 56
    • 36849088516 scopus 로고    scopus 로고
    • The RTK/RAS/BRAF/PI3K pathways in melanoma: Biology, small molecule inhibitors, and potential applications
    • Haluska, F., Pemberton, T., Ibrahim, N. Kalinsky, K. (2007). The RTK/RAS/BRAF/PI3K pathways in melanoma: biology, small molecule inhibitors, and potential applications. Semin. Oncol. 34, 546 554.
    • (2007) Semin. Oncol. , vol.34 , pp. 546-554
    • Haluska, F.1    Pemberton, T.2    Ibrahim, N.3    Kalinsky, K.4
  • 57
    • 0034730150 scopus 로고    scopus 로고
    • Contact with fibrillar collagen inhibits melanoma cell proliferation by up-regulating p27KIP1
    • Henriet, P., Zhong, Z.D., Brooks, P.C., Weinberg, K.I. Declerck, Y.A. (2000). Contact with fibrillar collagen inhibits melanoma cell proliferation by up-regulating p27KIP1. Proc. Natl Acad. Sci. USA 97, 10026 10031.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 10026-10031
    • Henriet, P.1    Zhong, Z.D.2    Brooks, P.C.3    Weinberg, K.I.4    Declerck, Y.A.5
  • 59
    • 0033838767 scopus 로고    scopus 로고
    • E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors
    • Hsu, M.Y., Meier, F.E., Nesbit, M., Hsu, J.Y., Van Belle, P., Elder, D.E. Herlyn, M. (2000). E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am. J. Pathol. 156, 1515 1525.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1515-1525
    • Hsu, M.Y.1    Meier, F.E.2    Nesbit, M.3    Hsu, J.Y.4    Van Belle, P.5    Elder, D.E.6    Herlyn, M.7
  • 61
    • 37349079197 scopus 로고    scopus 로고
    • Systemic spread is an early step in breast cancer
    • Husemann, Y., Geigl, J.B., Schubert, F. et al. (2008). Systemic spread is an early step in breast cancer. Cancer Cell 13, 58 68.
    • (2008) Cancer Cell , vol.13 , pp. 58-68
    • Husemann, Y.1    Geigl, J.B.2    Schubert, F.3
  • 62
    • 20744431757 scopus 로고    scopus 로고
    • Transforming growth factor-beta and malignant melanoma: Molecular mechanisms
    • Hussein, M.R. (2005). Transforming growth factor-beta and malignant melanoma: molecular mechanisms. J. Cutan. Pathol. 32, 389 395.
    • (2005) J. Cutan. Pathol. , vol.32 , pp. 389-395
    • Hussein, M.R.1
  • 65
    • 0026725897 scopus 로고
    • Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells
    • Kalinec, G., Nazarali, A.J., Hermouet, S., Xu, N. Gutkind, J.S. (1992). Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells. Mol. Cell. Biol. 12, 4687 4693.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4687-4693
    • Kalinec, G.1    Nazarali, A.J.2    Hermouet, S.3    Xu, N.4    Gutkind, J.S.5
  • 66
    • 34248524006 scopus 로고    scopus 로고
    • Novel inhibitors in the treatment of metastatic melanoma
    • Kalinsky, K. Haluska, F.G. (2007). Novel inhibitors in the treatment of metastatic melanoma. Expert Rev. Anticancer Ther. 7, 715 724.
    • (2007) Expert Rev. Anticancer Ther. , vol.7 , pp. 715-724
    • Kalinsky, K.1    Haluska, F.G.2
  • 67
    • 34547113747 scopus 로고    scopus 로고
    • Tumor growth need not be driven by rare cancer stem cells
    • Kelly, P.N., Dakic, A., Adams, J.M., Nutt, S.L. Strasser, A. (2007). Tumor growth need not be driven by rare cancer stem cells. Science 317, 337.
    • (2007) Science , vol.317 , pp. 337
    • Kelly, P.N.1    Dakic, A.2    Adams, J.M.3    Nutt, S.L.4    Strasser, A.5
  • 68
    • 48349095740 scopus 로고    scopus 로고
    • Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
    • Kim, J.B., Zaehres, H., Wu, G. et al. (2008). Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 454, 646 650.
    • (2008) Nature , vol.454 , pp. 646-650
    • Kim, J.B.1    Zaehres, H.2    Wu, G.3
  • 69
    • 56949091588 scopus 로고    scopus 로고
    • The direct molecular analysis of metastatic precursor cells in breast cancer: A chance for a better understanding of metastasis and for personalised medicine
    • Klein, C.A. (2008). The direct molecular analysis of metastatic precursor cells in breast cancer: a chance for a better understanding of metastasis and for personalised medicine. Eur. J. Cancer 44, 2721 2725.
    • (2008) Eur. J. Cancer , vol.44 , pp. 2721-2725
    • Klein, C.A.1
  • 70
    • 33748924308 scopus 로고    scopus 로고
    • Systemic cancer progression and tumor dormancy: Mathematical models meet single cell genomics
    • Klein, C.A. Hölzel, D. (2006). Systemic cancer progression and tumor dormancy: mathematical models meet single cell genomics. Cell Cycle 5, 1788 1798.
    • (2006) Cell Cycle , vol.5 , pp. 1788-1798
    • Klein, C.A.1    Hölzel, D.2
  • 73
    • 0035397653 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases control p27/Kip1 expression and growth of human melanoma cells
    • Kortylewski, M., Heinrich, P.C., Kauffmann, M.E., Bohm, M., Mackiewicz, A. Behrmann, I. (2001). Mitogen-activated protein kinases control p27/Kip1 expression and growth of human melanoma cells. Biochem. J. 357, 297 303.
    • (2001) Biochem. J. , vol.357 , pp. 297-303
    • Kortylewski, M.1    Heinrich, P.C.2    Kauffmann, M.E.3    Bohm, M.4    MacKiewicz, A.5    Behrmann, I.6
  • 76
    • 44849143723 scopus 로고    scopus 로고
    • Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation
    • Le Scolan, E., Zhu, Q., Wang, L., Bandyopadhyay, A., Javelaud, D., Mauviel, A., Sun, L. Luo, K. (2008). Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation. Cancer Res. 68, 3277 3285.
    • (2008) Cancer Res. , vol.68 , pp. 3277-3285
    • Le Scolan, E.1    Zhu, Q.2    Wang, L.3    Bandyopadhyay, A.4    Javelaud, D.5    Mauviel, A.6    Sun, L.7    Luo, K.8
  • 77
    • 0347363828 scopus 로고    scopus 로고
    • Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells
    • Lefevre, G., Calipel, A., Mouriaux, F., Hecquet, C., Malecaze, F. Mascarelli, F. (2003). Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells. Oncogene 22, 8813 8822.
    • (2003) Oncogene , vol.22 , pp. 8813-8822
    • Lefevre, G.1    Calipel, A.2    Mouriaux, F.3    Hecquet, C.4    Malecaze, F.5    Mascarelli, F.6
  • 79
    • 18644376449 scopus 로고    scopus 로고
    • PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest
    • Liang, J., Zubovitz, J., Petrocelli, T. et al. (2002). PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest. Nat. Med. 8, 1153 1160.
    • (2002) Nat. Med. , vol.8 , pp. 1153-1160
    • Liang, J.1    Zubovitz, J.2    Petrocelli, T.3
  • 80
    • 33947250696 scopus 로고    scopus 로고
    • The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis
    • Liang, J., Shao, S.H., Xu, Z.X. et al. (2007). The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat. Cell Biol. 9, 218 224.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 218-224
    • Liang, J.1    Shao, S.H.2    Xu, Z.X.3
  • 81
    • 64049087382 scopus 로고    scopus 로고
    • Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB
    • Lin, H.K., Wang, G., Chen, Z. et al. (2009). Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nat. Cell Biol. 11, 420 432.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 420-432
    • Lin, H.K.1    Wang, G.2    Chen, Z.3
  • 82
    • 0036596352 scopus 로고    scopus 로고
    • EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma
    • Liu, D., Aguirre Ghiso, J., Estrada, Y. Ossowski, L. (2002). EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma. Cancer Cell 1, 445 457.
    • (2002) Cancer Cell , vol.1 , pp. 445-457
    • Liu, D.1    Aguirre Ghiso, J.2    Estrada, Y.3    Ossowski, L.4
  • 83
    • 33646257783 scopus 로고    scopus 로고
    • Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression
    • Liu, Z.J., Xiao, M., Balint, K., Smalley, K.S., Brafford, P., Qiu, R., Pinnix, C.C., Li, X. Herlyn, M. (2006). Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression. Cancer Res. 66, 4182 4190.
    • (2006) Cancer Res. , vol.66 , pp. 4182-4190
    • Liu, Z.J.1    Xiao, M.2    Balint, K.3    Smalley, K.S.4    Brafford, P.5    Qiu, R.6    Pinnix, C.C.7    Li, X.8    Herlyn, M.9
  • 85
    • 34247606483 scopus 로고    scopus 로고
    • Rewired ERK-JNK signaling pathways in melanoma
    • Lopez-Bergami, P., Huang, C., Goydos, J.S. et al. (2007). Rewired ERK-JNK signaling pathways in melanoma. Cancer Cell 11, 447 460.
    • (2007) Cancer Cell , vol.11 , pp. 447-460
    • Lopez-Bergami, P.1    Huang, C.2    Goydos, J.S.3
  • 87
    • 41949106667 scopus 로고    scopus 로고
    • Systemic therapy for metastatic malignant melanoma-from deeply disappointing to bright future?
    • Lorigan, P., Eisen, T. Hauschild, A. (2008). Systemic therapy for metastatic malignant melanoma-from deeply disappointing to bright future? Exp. Dermatol. 17, 383 394.
    • (2008) Exp. Dermatol. , vol.17 , pp. 383-394
    • Lorigan, P.1    Eisen, T.2    Hauschild, A.3
  • 88
    • 0037421593 scopus 로고    scopus 로고
    • Fatal melanoma transferred in a donated kidney 16 years after melanoma surgery
    • Mackie, R.M., Reid, R. Junor, B. (2003). Fatal melanoma transferred in a donated kidney 16 years after melanoma surgery. N. Engl. J. Med. 348, 567 568.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 567-568
    • MacKie, R.M.1    Reid, R.2    Junor, B.3
  • 90
    • 21244484329 scopus 로고    scopus 로고
    • Maintenance of long-term tumour-specific T-cell memory by residual dormant tumour cells
    • Mahnke, Y.D., Schwendemann, J., Beckhove, P. Schirrmacher, V. (2005). Maintenance of long-term tumour-specific T-cell memory by residual dormant tumour cells. Immunology 115, 325 336.
    • (2005) Immunology , vol.115 , pp. 325-336
    • Mahnke, Y.D.1    Schwendemann, J.2    Beckhove, P.3    Schirrmacher, V.4
  • 91
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani, S.A., Guo, W., Liao, M.J. et al. (2008). The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133, 704 715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3
  • 92
    • 0032519525 scopus 로고    scopus 로고
    • Cancer dormancy: Role of cyclin-dependent kinase inhibitors in induction of cell cycle arrest mediated via membrane IgM
    • Marches, R., Scheuermann, R.H. Uhr, J.W. (1998). Cancer dormancy: role of cyclin-dependent kinase inhibitors in induction of cell cycle arrest mediated via membrane IgM. Cancer Res. 58, 691 697.
    • (1998) Cancer Res. , vol.58 , pp. 691-697
    • Marches, R.1    Scheuermann, R.H.2    Uhr, J.W.3
  • 93
    • 0033587731 scopus 로고    scopus 로고
    • Cancer dormancy and cell signaling: Induction of p21(waf1) initiated by membrane IgM engagement increases survival of B lymphoma cells
    • Marches, R., Hsueh, R. Uhr, J.W. (1999). Cancer dormancy and cell signaling: induction of p21(waf1) initiated by membrane IgM engagement increases survival of B lymphoma cells. Proc. Natl Acad. Sci. USA 96, 8711 8715.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 8711-8715
    • Marches, R.1    Hsueh, R.2    Uhr, J.W.3
  • 94
    • 33748941237 scopus 로고    scopus 로고
    • Cancer dormancy from mice to man: A review
    • Marches, R., Scheuermann, R.H. Uhr, J. (2006). Cancer dormancy from mice to man: a review. Cell Cycle 5, 1772 1778.
    • (2006) Cell Cycle , vol.5 , pp. 1772-1778
    • Marches, R.1    Scheuermann, R.H.2    Uhr, J.3
  • 96
    • 33847639310 scopus 로고    scopus 로고
    • Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential
    • Monzani, E., Facchetti, F., Galmozzi, E. et al. (2007). Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential. Eur. J. Cancer 43, 935 946.
    • (2007) Eur. J. Cancer , vol.43 , pp. 935-946
    • Monzani, E.1    Facchetti, F.2    Galmozzi, E.3
  • 97
    • 33847784034 scopus 로고    scopus 로고
    • Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy
    • Nash, K.T., Phadke, P.A., Navenot, J.M. et al. (2007). Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy. J. Natl Cancer Inst. 99, 309 321.
    • (2007) J. Natl Cancer Inst. , vol.99 , pp. 309-321
    • Nash, K.T.1    Phadke, P.A.2    Navenot, J.M.3
  • 98
    • 33748940402 scopus 로고    scopus 로고
    • Role of angiogenesis in human tumor dormancy: Animal models of the angiogenic switch
    • Naumov, G.N., Akslen, L.A. Folkman, J. (2006). Role of angiogenesis in human tumor dormancy: animal models of the angiogenic switch. Cell Cycle 5, 1779 1787. (Pubitemid 44435320)
    • (2006) Cell Cycle , vol.5 , Issue.16 , pp. 1779-1787
    • Naumov, G.N.1    Akslen, L.A.2    Folkman, J.3
  • 100
    • 67651183589 scopus 로고    scopus 로고
    • Immune escape mechanisms of intraocular tumors
    • Niederkorn, J.Y. (2009). Immune escape mechanisms of intraocular tumors. Prog. Retin. Eye Res. 28, 329 347.
    • (2009) Prog. Retin. Eye Res. , vol.28 , pp. 329-347
    • Niederkorn, J.Y.1
  • 101
    • 0036376720 scopus 로고    scopus 로고
    • Tumor progression: A brief historical perspective
    • Nowell, P.C. (2002). Tumor progression: a brief historical perspective. Semin. Cancer Biol. 12, 261 266.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 261-266
    • Nowell, P.C.1
  • 104
    • 0018828416 scopus 로고
    • Loss of malignancy during serial passage of human carcinoma in culture and discordance between malignancy and transformation parameters
    • Ossowski, L. Reich, E. (1980). Loss of malignancy during serial passage of human carcinoma in culture and discordance between malignancy and transformation parameters. Cancer Res. 40, 2310 2315.
    • (1980) Cancer Res. , vol.40 , pp. 2310-2315
    • Ossowski, L.1    Reich, E.2
  • 105
    • 0020621220 scopus 로고
    • Changes in malignant phenotype of a human carcinoma conditioned by growth environment
    • Ossowski, L. Reich, E. (1983). Changes in malignant phenotype of a human carcinoma conditioned by growth environment. Cell 33, 323 333.
    • (1983) Cell , vol.33 , pp. 323-333
    • Ossowski, L.1    Reich, E.2
  • 106
    • 50549121134 scopus 로고
    • The distribution of secondary growths in cancer of the breast
    • Paget, S. (1889). The distribution of secondary growths in cancer of the breast. Lancet 1, 571 573.
    • (1889) Lancet , vol.1 , pp. 571-573
    • Paget, S.1
  • 107
    • 2942538264 scopus 로고    scopus 로고
    • Dissecting the metastatic cascade
    • Pantel, K. Brakenhoff, R.H. (2004). Dissecting the metastatic cascade. Nat. Rev. Cancer 4, 448 456.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 448-456
    • Pantel, K.1    Brakenhoff, R.H.2
  • 110
    • 0030040747 scopus 로고    scopus 로고
    • Malignant melanoma in organ allograft recipients
    • Penn, I. (1996). Malignant melanoma in organ allograft recipients. Transplantation 61, 274 278.
    • (1996) Transplantation , vol.61 , pp. 274-278
    • Penn, I.1
  • 111
    • 0030955819 scopus 로고    scopus 로고
    • First melanoma metastases after 10 years and more of remission
    • Peters, A., Lippold, A. Hundeiker, M. (1997). First melanoma metastases after 10 years and more of remission. Hautarzt 48, 311 317.
    • (1997) Hautarzt , vol.48 , pp. 311-317
    • Peters, A.1    Lippold, A.2    Hundeiker, M.3
  • 112
    • 30744454306 scopus 로고    scopus 로고
    • Cutaneous melanoma: Therapeutic lymph node and elective lymph node dissections, lymphatic mapping, and sentinel lymph node biopsy
    • Pharis, D.B. (2005). Cutaneous melanoma: therapeutic lymph node and elective lymph node dissections, lymphatic mapping, and sentinel lymph node biopsy. Dermatol. Ther. 18, 397 406.
    • (2005) Dermatol. Ther. , vol.18 , pp. 397-406
    • Pharis, D.B.1
  • 113
    • 67650458544 scopus 로고    scopus 로고
    • Active Notch1 confers a transformed phenotype to primary human melanocytes
    • Pinnix, C.C., Lee, J.T., Liu, Z.J. et al. (2009). Active Notch1 confers a transformed phenotype to primary human melanocytes. Cancer Res. 69, 5312 5320.
    • (2009) Cancer Res. , vol.69 , pp. 5312-5320
    • Pinnix, C.C.1    Lee, J.T.2    Liu, Z.J.3
  • 114
    • 67349215432 scopus 로고    scopus 로고
    • Melanoma vaccines: The problems of local immunosuppression
    • Polak, M.E., Borthwick, N.J., Jager, M.J. Cree, I.A. (2009). Melanoma vaccines: the problems of local immunosuppression. Hum. Immunol. 70, 331 339.
    • (2009) Hum. Immunol. , vol.70 , pp. 331-339
    • Polak, M.E.1    Borthwick, N.J.2    Jager, M.J.3    Cree, I.A.4
  • 115
    • 33744990640 scopus 로고    scopus 로고
    • A three-dimensional model to study the epigenetic effects induced by the microenvironment of human embryonic stem cells
    • Postovit, L.M., Seftor, E.A., Seftor, R.E. Hendrix, M.J. (2006). A three-dimensional model to study the epigenetic effects induced by the microenvironment of human embryonic stem cells. Stem Cells 24, 501 505.
    • (2006) Stem Cells , vol.24 , pp. 501-505
    • Postovit, L.M.1    Seftor, E.A.2    Seftor, R.E.3    Hendrix, M.J.4
  • 117
    • 34047111239 scopus 로고    scopus 로고
    • Cancer dormancy: Lessons from a B cell lymphoma and adenocarcinoma of the prostate
    • Rabinovsky, R., Uhr, J.W., Vitetta, E.S. Yefenof, E. (2007). Cancer dormancy: lessons from a B cell lymphoma and adenocarcinoma of the prostate. Adv. Cancer Res. 97, 189 202.
    • (2007) Adv. Cancer Res. , vol.97 , pp. 189-202
    • Rabinovsky, R.1    Uhr, J.W.2    Vitetta, E.S.3    Yefenof, E.4
  • 118
    • 34347210289 scopus 로고    scopus 로고
    • An update on malignant melanoma vaccine research: Insights into mechanisms for improving the design and potency of melanoma therapeutic vaccines
    • Ralph, S.J. (2007). An update on malignant melanoma vaccine research: insights into mechanisms for improving the design and potency of melanoma therapeutic vaccines. Am. J. Clin. Dermatol. 8, 123 141.
    • (2007) Am. J. Clin. Dermatol. , vol.8 , pp. 123-141
    • Ralph, S.J.1
  • 119
    • 32944478891 scopus 로고    scopus 로고
    • Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells
    • Ranganathan, A.C., Zhang, L., Adam, A.P. Aguirre-Ghiso, J.A. (2006). Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells. Cancer Res. 66, 1702 1711.
    • (2006) Cancer Res. , vol.66 , pp. 1702-1711
    • Ranganathan, A.C.1    Zhang, L.2    Adam, A.P.3    Aguirre-Ghiso, J.A.4
  • 120
    • 0035890377 scopus 로고    scopus 로고
    • Cytoplasmic localization of the oncogenic protein Ski in human cutaneous melanomas in vivo: Functional implications for transforming growth factor beta signaling
    • Reed, J.A., Bales, E., Xu, W., Okan, N.A., Bandyopadhyay, D. Medrano, E.E. (2001). Cytoplasmic localization of the oncogenic protein Ski in human cutaneous melanomas in vivo: functional implications for transforming growth factor beta signaling. Cancer Res. 61, 8074 8078.
    • (2001) Cancer Res. , vol.61 , pp. 8074-8078
    • Reed, J.A.1    Bales, E.2    Xu, W.3    Okan, N.A.4    Bandyopadhyay, D.5    Medrano, E.E.6
  • 122
    • 67649939163 scopus 로고    scopus 로고
    • The increasing complexity of the cancer stem cell paradigm
    • Rosen, J.M. Jordan, C.T. (2009). The increasing complexity of the cancer stem cell paradigm. Science 324, 1670 1673.
    • (2009) Science , vol.324 , pp. 1670-1673
    • Rosen, J.M.1    Jordan, C.T.2
  • 123
    • 33747584353 scopus 로고    scopus 로고
    • Anti-angiogenic therapy: Prospects for treatment of ocular tumors
    • Rosenblatt, M.I. Azar, D.T. (2006). Anti-angiogenic therapy: prospects for treatment of ocular tumors. Semin. Ophthalmol. 21, 151 160.
    • (2006) Semin. Ophthalmol. , vol.21 , pp. 151-160
    • Rosenblatt, M.I.1    Azar, D.T.2
  • 124
    • 33947305783 scopus 로고    scopus 로고
    • Epigenetic events in malignant melanoma
    • Rothhammer, T. Bosserhoff, A.K. (2007). Epigenetic events in malignant melanoma. Pigment Cell Res. 20, 92 111.
    • (2007) Pigment Cell Res. , vol.20 , pp. 92-111
    • Rothhammer, T.1    Bosserhoff, A.K.2
  • 126
    • 50149117285 scopus 로고    scopus 로고
    • Control of the reversibility of cellular quiescence by the transcriptional repressor HES1
    • Sang, L., Coller, H.A. Roberts, J.M. (2008). Control of the reversibility of cellular quiescence by the transcriptional repressor HES1. Science 321, 1095 1100.
    • (2008) Science , vol.321 , pp. 1095-1100
    • Sang, L.1    Coller, H.A.2    Roberts, J.M.3
  • 127
    • 36248964290 scopus 로고    scopus 로고
    • Reduced expression of p16 and p27 is correlated with tumour progression in cutaneous melanoma
    • Sanki, A., Li, W., Colman, M., Karim, R.Z., Thompson, J.F. Scolyer, R.A. (2007). Reduced expression of p16 and p27 is correlated with tumour progression in cutaneous melanoma. Pathology 39, 551 557.
    • (2007) Pathology , vol.39 , pp. 551-557
    • Sanki, A.1    Li, W.2    Colman, M.3    Karim, R.Z.4    Thompson, J.F.5    Scolyer, R.A.6
  • 128
    • 4644256639 scopus 로고    scopus 로고
    • In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis
    • Saudemont, A. Quesnel, B. (2004). In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis. Blood 104, 2124 2133.
    • (2004) Blood , vol.104 , pp. 2124-2133
    • Saudemont, A.1    Quesnel, B.2
  • 130
    • 38349165576 scopus 로고    scopus 로고
    • Identification of cells initiating human melanomas
    • Schatton, T., Murphy, G.F., Frank, N.Y. et al. (2008). Identification of cells initiating human melanomas. Nature 451, 345 349.
    • (2008) Nature , vol.451 , pp. 345-349
    • Schatton, T.1    Murphy, G.F.2    Frank, N.Y.3
  • 131
    • 48749105093 scopus 로고    scopus 로고
    • ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo
    • Schewe, D.M. Aguirre-Ghiso, J.A. (2008). ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo. Proc. Natl Acad. Sci. USA 105, 10519 10524.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 10519-10524
    • Schewe, D.M.1    Aguirre-Ghiso, J.A.2
  • 133
    • 0038271868 scopus 로고    scopus 로고
    • From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression
    • Schmidt-Kittler, O., Ragg, T., Daskalakis, A. et al. (2003). From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression. Proc. Natl Acad. Sci. USA 100, 7737 7742.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 7737-7742
    • Schmidt-Kittler, O.1    Ragg, T.2    Daskalakis, A.3
  • 137
    • 0034070390 scopus 로고    scopus 로고
    • Can elective lymph node dissection decrease the frequency and mortality rate of late melanoma recurrences?
    • Shen, P., Guenther, J.M., Wanek, L.A. Morton, D.L. (2000). Can elective lymph node dissection decrease the frequency and mortality rate of late melanoma recurrences? Ann. Surg. Oncol. 7, 114 119.
    • (2000) Ann. Surg. Oncol. , vol.7 , pp. 114-119
    • Shen, P.1    Guenther, J.M.2    Wanek, L.A.3    Morton, D.L.4
  • 138
    • 67649849871 scopus 로고    scopus 로고
    • Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
    • Shibue, T. Weinberg, R.A. (2009). Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc. Natl Acad. Sci. USA 106, 10290 10295.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 10290-10295
    • Shibue, T.1    Weinberg, R.A.2
  • 139
    • 74249098795 scopus 로고    scopus 로고
    • Update on posterior uveal melanoma: Treatment of the eye and emerging strategies in the prognosis and treatment of metastatic disease
    • Shildkrot, Y. Wilson, M.W. (2009). Update on posterior uveal melanoma: treatment of the eye and emerging strategies in the prognosis and treatment of metastatic disease. Curr. Opin. Ophthalmol., 20, 504 510.
    • (2009) Curr. Opin. Ophthalmol. , vol.20 , pp. 504-510
    • Shildkrot, Y.1    Wilson, M.W.2
  • 140
    • 1842428668 scopus 로고    scopus 로고
    • Incidence of BRAF oncogene mutation and clinical relevance for primary cutaneous melanomas
    • Shinozaki, M., Fujimoto, A., Morton, D.L. Hoon, D.S. (2004). Incidence of BRAF oncogene mutation and clinical relevance for primary cutaneous melanomas. Clin. Cancer Res. 10, 1753 1757.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 1753-1757
    • Shinozaki, M.1    Fujimoto, A.2    Morton, D.L.3    Hoon, D.S.4
  • 141
    • 42949150219 scopus 로고    scopus 로고
    • Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer
    • Stoecklein, N.H., Hosch, S.B., Bezler, M. et al. (2008). Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer. Cancer Cell 13, 441 453.
    • (2008) Cancer Cell , vol.13 , pp. 441-453
    • Stoecklein, N.H.1    Hosch, S.B.2    Bezler, M.3
  • 142
    • 34748849509 scopus 로고    scopus 로고
    • Vaccine therapy for melanoma: Current status and future directions
    • Terando, A.M., Faries, M.B. Morton, D.L. (2007). Vaccine therapy for melanoma: current status and future directions. Vaccine 25 (Suppl 2 B4 B16.
    • (2007) Vaccine , vol.25 , Issue.SUPPL. 2
    • Terando, A.M.1    Faries, M.B.2    Morton, D.L.3
  • 143
    • 33748937854 scopus 로고    scopus 로고
    • Dormancy of solitary metastatic cells
    • Townson, J.L. Chambers, A.F. (2006). Dormancy of solitary metastatic cells. Cell Cycle 5, 1744 1750.
    • (2006) Cell Cycle , vol.5 , pp. 1744-1750
    • Townson, J.L.1    Chambers, A.F.2
  • 145
    • 0030902368 scopus 로고    scopus 로고
    • Ultra-late recurrence (15 years or longer) of cutaneous melanoma
    • Tsao, H., Cosimi, A.B. Sober, A.J. (1997). Ultra-late recurrence (15 years or longer) of cutaneous melanoma. Cancer 79, 2361 2370.
    • (1997) Cancer , vol.79 , pp. 2361-2370
    • Tsao, H.1    Cosimi, A.B.2    Sober, A.J.3
  • 146
    • 51649086229 scopus 로고    scopus 로고
    • Visualization of circulating melanoma cells in peripheral blood of patients with primary uveal melanoma
    • Ulmer, A., Beutel, J., Susskind, D. et al. (2008). Visualization of circulating melanoma cells in peripheral blood of patients with primary uveal melanoma. Clin. Cancer Res. 14, 4469 4474.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 4469-4474
    • Ulmer, A.1    Beutel, J.2    Susskind, D.3
  • 147
    • 56449092100 scopus 로고    scopus 로고
    • Melanoma-specific memory T cells are functionally active in Ret transgenic mice without macroscopic tumors
    • Umansky, V., Abschuetz, O., Osen, W., Ramacher, M., Zhao, F., Kato, M. Schadendorf, D. (2008). Melanoma-specific memory T cells are functionally active in Ret transgenic mice without macroscopic tumors. Cancer Res. 68, 9451 9458.
    • (2008) Cancer Res. , vol.68 , pp. 9451-9458
    • Umansky, V.1    Abschuetz, O.2    Osen, W.3    Ramacher, M.4    Zhao, F.5    Kato, M.6    Schadendorf, D.7
  • 149
    • 35548958882 scopus 로고    scopus 로고
    • Tumor cell dormancy: An NCI workshop report
    • Vessella, R.L., Pantel, K. Mohla, S. (2007). Tumor cell dormancy: an NCI workshop report. Cancer Biol. Ther. 6, 1496 1504.
    • (2007) Cancer Biol. Ther. , vol.6 , pp. 1496-1504
    • Vessella, R.L.1    Pantel, K.2    Mohla, S.3
  • 150
    • 34247609756 scopus 로고    scopus 로고
    • Prognostic role of circulating melanoma cells detected by reverse transcriptase-polymerase chain reaction for tyrosinase mRNA in patients with melanoma
    • Visús, C., Andres, R., Mayordomo, J.I. et al. (2007). Prognostic role of circulating melanoma cells detected by reverse transcriptase-polymerase chain reaction for tyrosinase mRNA in patients with melanoma. Melanoma Res. 73, 83 89.
    • (2007) Melanoma Res. , vol.73 , pp. 83-89
    • Visús, C.1    Andres, R.2    Mayordomo, J.I.3
  • 151
    • 38849168162 scopus 로고    scopus 로고
    • Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
    • Wajapeyee, N., Serra, R.W., Zhu, X., Mahalingam, M. Green, M.R. (2008). Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 132, 363 374.
    • (2008) Cell , vol.132 , pp. 363-374
    • Wajapeyee, N.1    Serra, R.W.2    Zhu, X.3    Mahalingam, M.4    Green, M.R.5
  • 152
    • 28844477778 scopus 로고    scopus 로고
    • Discoidin domain receptor 2 mediates tumor cell cycle arrest induced by fibrillar collagen
    • Wall, S.J., Werner, E., Werb, Z. Declerck, Y.A. (2005). Discoidin domain receptor 2 mediates tumor cell cycle arrest induced by fibrillar collagen. J. Biol. Chem. 280, 40187 40194.
    • (2005) J. Biol. Chem. , vol.280 , pp. 40187-40194
    • Wall, S.J.1    Werner, E.2    Werb, Z.3    Declerck, Y.A.4
  • 153
    • 34548270562 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitors p15INK4B and p21CIP1 are critical regulators of fibrillar collagen-induced tumor cell cycle arrest
    • Wall, S.J., Zhong, Z.D. Declerck, Y.A. (2007). The cyclin-dependent kinase inhibitors p15INK4B and p21CIP1 are critical regulators of fibrillar collagen-induced tumor cell cycle arrest. J. Biol. Chem. 282, 24471 24476.
    • (2007) J. Biol. Chem. , vol.282 , pp. 24471-24476
    • Wall, S.J.1    Zhong, Z.D.2    Declerck, Y.A.3
  • 154
    • 0037025173 scopus 로고    scopus 로고
    • Cancer. Addiction to oncogenes-the Achilles heal of cancer
    • Weinstein, I.B. (2002). Cancer. Addiction to oncogenes-the Achilles heal of cancer. Science 297, 63 64.
    • (2002) Science , vol.297 , pp. 63-64
    • Weinstein, I.B.1
  • 155
    • 5144235557 scopus 로고    scopus 로고
    • Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
    • White, D.E., Kurpios, N.A., Zuo, D., Hassell, J.A., Blaess, S., Mueller, U. Muller, W.J. (2004). Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell 6, 159 170.
    • (2004) Cancer Cell , vol.6 , pp. 159-170
    • White, D.E.1    Kurpios, N.A.2    Zuo, D.3    Hassell, J.A.4    Blaess, S.5    Mueller, U.6    Muller, W.J.7
  • 156
    • 0036568378 scopus 로고    scopus 로고
    • Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma
    • Whiteman, D.C., Zhou, X.P., Cummings, M.C., Pavey, S., Hayward, N.K. Eng, C. (2002). Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma. Int. J. Cancer 99, 63 67.
    • (2002) Int. J. Cancer , vol.99 , pp. 63-67
    • Whiteman, D.C.1    Zhou, X.P.2    Cummings, M.C.3    Pavey, S.4    Hayward, N.K.5    Eng, C.6
  • 157
    • 52049116094 scopus 로고    scopus 로고
    • Cancer micrometastasis and tumour dormancy
    • Wikman, H., Vessella, R. Pantel, K. (2008). Cancer micrometastasis and tumour dormancy. APMIS 116, 754 770.
    • (2008) APMIS , vol.116 , pp. 754-770
    • Wikman, H.1    Vessella, R.2    Pantel, K.3
  • 158
    • 24344436369 scopus 로고    scopus 로고
    • Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance
    • Willimsky, G. Blankenstein, T. (2005). Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance. Nature 437, 141 146.
    • (2005) Nature , vol.437 , pp. 141-146
    • Willimsky, G.1    Blankenstein, T.2
  • 159
    • 56549128268 scopus 로고    scopus 로고
    • Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
    • Wilson, A., Laurenti, E., Oser, G. et al. (2008). Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 135, 1118 1129.
    • (2008) Cell , vol.135 , pp. 1118-1129
    • Wilson, A.1    Laurenti, E.2    Oser, G.3
  • 160
    • 33747620742 scopus 로고    scopus 로고
    • Melanoma growth is reduced in fat-1 transgenic mice: Impact of omega-6/omega-3 essential fatty acids
    • Xia, S., Lu, Y., Wang, J., He, C., Hong, S., Serhan, C.N. Kang, J.X. (2006). Melanoma growth is reduced in fat-1 transgenic mice: impact of omega-6/omega-3 essential fatty acids. Proc. Natl Acad. Sci. USA 103, 12499 12504.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 12499-12504
    • Xia, S.1    Lu, Y.2    Wang, J.3    He, C.4    Hong, S.5    Serhan, C.N.6    Kang, J.X.7
  • 161
    • 0141610028 scopus 로고    scopus 로고
    • The risk of regional lymph node metastases in patients with melanoma less than 1.0 mm thick: Recommendations for sentinel lymph node biopsy
    • Zapas, J.L., Coley, H.C., Beam, S.L., Brown, S.D., Jablonski, K.A. Elias, E.G. (2003). The risk of regional lymph node metastases in patients with melanoma less than 1.0 mm thick: recommendations for sentinel lymph node biopsy. J. Am. Coll. Surg. 197, 403 407.
    • (2003) J. Am. Coll. Surg. , vol.197 , pp. 403-407
    • Zapas, J.L.1    Coley, H.C.2    Beam, S.L.3    Brown, S.D.4    Jablonski, K.A.5    Elias, E.G.6
  • 162
    • 0033819340 scopus 로고    scopus 로고
    • Epigenetic PTEN silencing in malignant melanomas without PTEN mutation
    • Zhou, X.P., Gimm, O., Hampel, H., Niemann, T., Walker, M.J. Eng, C. (2000). Epigenetic PTEN silencing in malignant melanomas without PTEN mutation. Am. J. Pathol. 157, 1123 1128.
    • (2000) Am. J. Pathol. , vol.157 , pp. 1123-1128
    • Zhou, X.P.1    Gimm, O.2    Hampel, H.3    Niemann, T.4    Walker, M.J.5    Eng, C.6


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