-
1
-
-
24944459911
-
Use of cytokines in cancer vaccines/immunotherapy: Recent developments improve survival rates for patients with metastatic malignancy
-
Dezfouli S, Hatzinisiriou I, Ralph SJ. Use of cytokines in cancer vaccines/immunotherapy: recent developments improve survival rates for patients with metastatic malignancy. Curr Pharm Des 2005; 11 (27): 3511-30
-
(2005)
Curr Pharm Des
, vol.11
, Issue.27
, pp. 3511-3530
-
-
Dezfouli, S.1
Hatzinisiriou, I.2
Ralph, S.J.3
-
3
-
-
33748805767
-
The treatment of melanoma with an emphasis on immunotherapeutic strategies
-
Jun 29;
-
Jack A, Boyes C, Aydin N, et al. The treatment of melanoma with an emphasis on immunotherapeutic strategies. Surg Oncol 2006 Jun 29; 15 (1): 13-24
-
(2006)
Surg Oncol
, vol.15
, Issue.1
, pp. 13-24
-
-
Jack, A.1
Boyes, C.2
Aydin, N.3
-
4
-
-
33646033135
-
Evaluation of immunotherapy in the treatment of melanoma
-
Apr;
-
Faries MB. Evaluation of immunotherapy in the treatment of melanoma. Surg Oncol Clin N Am 2006 Apr; 15 (2): 399-418
-
(2006)
Surg Oncol Clin N Am
, vol.15
, Issue.2
, pp. 399-418
-
-
Faries, M.B.1
-
5
-
-
33646254412
-
Strategies for the development of more effective adjuvant therapy of melanoma: Current and future explorations of antibodies, cytokines, vaccines, and combinations
-
Apr 1;, s
-
Kirkwood JM, Moschos S, Wang W. Strategies for the development of more effective adjuvant therapy of melanoma: current and future explorations of antibodies, cytokines, vaccines, and combinations. Clin Cancer Res 2006 Apr 1; 12 (7 Pt 2): 2331s-6s
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 PART 2
-
-
Kirkwood, J.M.1
Moschos, S.2
Wang, W.3
-
6
-
-
33646255944
-
Allogeneic and autologous melanoma vaccines: Where have we been and where are we going?
-
Apr 1;, s
-
Sondak VK, Sabel MS, Mule JJ. Allogeneic and autologous melanoma vaccines: where have we been and where are we going? Clin Cancer Res 2006 Apr 1; 12 (7 Pt 2): 2337s-41s
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 PART 2
-
-
Sondak, V.K.1
Sabel, M.S.2
Mule, J.J.3
-
7
-
-
33747661085
-
Update on immunotherapy for melanoma
-
Aug 4;
-
Ribas A. Update on immunotherapy for melanoma. J Natl Compr Canc Netw 2006 Aug 4; (7): 687-94
-
(2006)
J Natl Compr Canc Netw
, vol.7
, pp. 687-694
-
-
Ribas, A.1
-
8
-
-
5144226237
-
Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes
-
Oct 5;
-
Rosenberg SA, Dudley ME. Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes. Proc Natl Acad Sci U S A 2004 Oct 5; 101 Suppl. 2: 14639-45
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.SUPPL. 2
, pp. 14639-14645
-
-
Rosenberg, S.A.1
Dudley, M.E.2
-
9
-
-
20244366111
-
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
-
Apr 1;
-
Dudley ME, Wunderlich JR, Yang JC, et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol 2005 Apr 1; 23 (10): 2346-57
-
(2005)
J Clin Oncol
, vol.23
, Issue.10
, pp. 2346-2357
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Yang, J.C.3
-
10
-
-
33646356996
-
Adoptive immunotherapy for cancer: Building on success
-
May;
-
Gattinoni L, Powell Jr DJ, Rosenberg SA, et al. Adoptive immunotherapy for cancer: building on success. Nat Rev Immunol 2006 May; 6 (5): 383-93
-
(2006)
Nat Rev Immunol
, vol.6
, Issue.5
, pp. 383-393
-
-
Gattinoni, L.1
Powell Jr, D.J.2
Rosenberg, S.A.3
-
11
-
-
10344261422
-
Cutting edge: Persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
-
Dec 15;
-
Robbins PF, Dudley ME, Wunderlich J, et al. Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy. J Immunol 2004 Dec 15; 173 (12): 7125-30
-
(2004)
J Immunol
, vol.173
, Issue.12
, pp. 7125-7130
-
-
Robbins, P.F.1
Dudley, M.E.2
Wunderlich, J.3
-
12
-
-
24944477490
-
Direct evidence on the immune-mediated spontaneous regression of human cancer: An incentive for pharmaceutical companies to develop a novel anti-cancer vaccine
-
Saleh F, Renno W, Klepacek I, et al. Direct evidence on the immune-mediated spontaneous regression of human cancer: an incentive for pharmaceutical companies to develop a novel anti-cancer vaccine. Curr Pharm Des 2005; 11 (27): 3531-43
-
(2005)
Curr Pharm Des
, vol.11
, Issue.27
, pp. 3531-3543
-
-
Saleh, F.1
Renno, W.2
Klepacek, I.3
-
13
-
-
24944495579
-
Melanoma immunotherapy: Past, present, and future
-
Saleh F, Renno W, Klepacek I, et al. Melanoma immunotherapy: past, present, and future. Curr Pharm Des 2005; 11 (27): 3461-73
-
(2005)
Curr Pharm Des
, vol.11
, Issue.27
, pp. 3461-3473
-
-
Saleh, F.1
Renno, W.2
Klepacek, I.3
-
14
-
-
0037943937
-
Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendritic cell vaccine
-
Jun;
-
O'Rourke MG, Johnson M, Lanagan C, et al. Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendritic cell vaccine. Cancer Immunol Immunother 2003 Jun; 52 (6): 387-95
-
(2003)
Cancer Immunol Immunother
, vol.52
, Issue.6
, pp. 387-395
-
-
O'Rourke, M.G.1
Johnson, M.2
Lanagan, C.3
-
15
-
-
0036896972
-
Prolonged survival after complete resection of disseminated melanoma and active immunotherapy with a therapeutic cancer vaccine
-
Dec 1;
-
Hsueh EC, Essner R, Foshag LJ, et al. Prolonged survival after complete resection of disseminated melanoma and active immunotherapy with a therapeutic cancer vaccine. J Clin Oncol 2002 Dec 1; 20 (23): 4549-54
-
(2002)
J Clin Oncol
, vol.20
, Issue.23
, pp. 4549-4554
-
-
Hsueh, E.C.1
Essner, R.2
Foshag, L.J.3
-
16
-
-
33645922486
-
Principles of the therapeutic use of monoclonal antibodies in oncology
-
Apr;
-
Fridman WH. Principles of the therapeutic use of monoclonal antibodies in oncology. C R Biol 2006 Apr; 329 (4): 255-9
-
(2006)
C R Biol
, vol.329
, Issue.4
, pp. 255-259
-
-
Fridman, W.H.1
-
17
-
-
0023939724
-
Time and frequency of recurrence of cutaneous stage I malignant melanoma with guidelines for follow-up study
-
Jun;
-
McCarthy WH, Shaw HM, Thompson JF, et al. Time and frequency of recurrence of cutaneous stage I malignant melanoma with guidelines for follow-up study. Surg Gynecol Obstet 1988 Jun; 166 (6): 497-502
-
(1988)
Surg Gynecol Obstet
, vol.166
, Issue.6
, pp. 497-502
-
-
McCarthy, W.H.1
Shaw, H.M.2
Thompson, J.F.3
-
18
-
-
0031969032
-
Factors affecting survival following local, regional, or distant recurrence from localized melanoma
-
Apr;
-
Soong SJ, Harrison RA, McCarthy WH, et al. Factors affecting survival following local, regional, or distant recurrence from localized melanoma. J Surg Oncol 1998 Apr; 67 (4): 228-33
-
(1998)
J Surg Oncol
, vol.67
, Issue.4
, pp. 228-233
-
-
Soong, S.J.1
Harrison, R.A.2
McCarthy, W.H.3
-
19
-
-
33746006527
-
Clinical results of vaccine therapy for cancer: Learning from history for improving the future
-
Choudhury A, Mosolits S, Kokhaei P, et al. Clinical results of vaccine therapy for cancer: learning from history for improving the future. Adv Cancer Res 2006; 95: 147-202
-
(2006)
Adv Cancer Res
, vol.95
, pp. 147-202
-
-
Choudhury, A.1
Mosolits, S.2
Kokhaei, P.3
-
20
-
-
0034772102
-
Double-blind trial of a polyvalent, shed-antigen, melanoma vaccine
-
Jul;
-
Bystryn JC, Zeleniuch-Jacquotte A, Oratz R, et al. Double-blind trial of a polyvalent, shed-antigen, melanoma vaccine. Clin Cancer Res 2001 Jul; 7 (7): 1882-7
-
(2001)
Clin Cancer Res
, vol.7
, Issue.7
, pp. 1882-1887
-
-
Bystryn, J.C.1
Zeleniuch-Jacquotte, A.2
Oratz, R.3
-
21
-
-
24044539856
-
Cancer vaccine potency: Is there a dose/response relationship for patient-specific vaccines and clinical outcomes?
-
Aug;
-
Dillman RO, Beutel L, Nayak S, et al. Cancer vaccine potency: is there a dose/response relationship for patient-specific vaccines and clinical outcomes? Cancer Biother Radiopharm 2005 Aug; 20 (4): 373-8
-
(2005)
Cancer Biother Radiopharm
, vol.20
, Issue.4
, pp. 373-378
-
-
Dillman, R.O.1
Beutel, L.2
Nayak, S.3
-
22
-
-
11844275325
-
Use of standard criteria for assessment of cancer vaccines
-
Jan;
-
Restifo NP, Rosenberg SA. Use of standard criteria for assessment of cancer vaccines. Lancet Oncol 2005 Jan; 6 (1): 3-4
-
(2005)
Lancet Oncol
, vol.6
, Issue.1
, pp. 3-4
-
-
Restifo, N.P.1
Rosenberg, S.A.2
-
23
-
-
22244476068
-
Sustained low-level expression of interferon-gamma promotes tumor development: Potential insights in tumor prevention and tumor immunotherapy
-
Sep;
-
He YF, Wang XH, Zhang GM, et al. Sustained low-level expression of interferon-gamma promotes tumor development: potential insights in tumor prevention and tumor immunotherapy. Cancer Immunol Immunother 2005 Sep; 54 (9): 891-7
-
(2005)
Cancer Immunol Immunother
, vol.54
, Issue.9
, pp. 891-897
-
-
He, Y.F.1
Wang, X.H.2
Zhang, G.M.3
-
24
-
-
0035266248
-
Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis by independent mechanisms
-
Mar 1;
-
Mann A, Breuhahn K, Schirmacher P, et al. Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis by independent mechanisms. Cancer Res 2001 Mar 1; 61 (5): 2311-9
-
(2001)
Cancer Res
, vol.61
, Issue.5
, pp. 2311-2319
-
-
Mann, A.1
Breuhahn, K.2
Schirmacher, P.3
-
25
-
-
0346752502
-
-
Eves P, Haycock J, Layton C, et al. Anti-inflammatory and anti-invasive effects of alpha-melanocyte-stimulating hormone in human melanoma cells. Br J Cancer 2003 Nov 17; 89 (10): 2004-15
-
Eves P, Haycock J, Layton C, et al. Anti-inflammatory and anti-invasive effects of alpha-melanocyte-stimulating hormone in human melanoma cells. Br J Cancer 2003 Nov 17; 89 (10): 2004-15
-
-
-
-
26
-
-
31544444698
-
Alpha-melanocyte stimulating hormone, inflammation and human melanoma
-
Feb;
-
Eves PC, MacNeil S, Haycock JW. Alpha-melanocyte stimulating hormone, inflammation and human melanoma. Peptides 2006 Feb; 27 (2): 444-52
-
(2006)
Peptides
, vol.27
, Issue.2
, pp. 444-452
-
-
Eves, P.C.1
MacNeil, S.2
Haycock, J.W.3
-
27
-
-
39049106146
-
-
Ralph SJ, Low P, Dong L, et al. Mitocans: mitochondrial targeted anti-cancer drugs as improved therapies and related patent documents. Recent Patents Anti-Cancer Drug Discov 2006 Nov; 1 (3): 327-46
-
Ralph SJ, Low P, Dong L, et al. Mitocans: mitochondrial targeted anti-cancer drugs as improved therapies and related patent documents. Recent Patents Anti-Cancer Drug Discov 2006 Nov; 1 (3): 327-46
-
-
-
-
29
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
Nov 17;
-
Curtin JA, Fridlyand J, Kageshita T, et al. Distinct sets of genetic alterations in melanoma. N Engl J Med 2005 Nov 17; 353 (20): 2135-47
-
(2005)
N Engl J Med
, vol.353
, Issue.20
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
-
30
-
-
24944475592
-
STAT5 contributes to interferon resistance of melanoma cells
-
Sep 20;
-
Wellbrock C, Weisser C, Hassel JC, et al. STAT5 contributes to interferon resistance of melanoma cells. Curr Biol 2005 Sep 20; 15 (18): 1629-39
-
(2005)
Curr Biol
, vol.15
, Issue.18
, pp. 1629-1639
-
-
Wellbrock, C.1
Weisser, C.2
Hassel, J.C.3
-
31
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Jun 27;
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002 Jun 27; 417 (6892): 949-54
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
32
-
-
0036894746
-
BRAF and RAS mutations in human lung cancer and melanoma
-
Dec 1;
-
Brose MS, Volpe P, Feldman M, et al. BRAF and RAS mutations in human lung cancer and melanoma. Cancer Res 2002 Dec 1; 62 (23): 6997-7000
-
(2002)
Cancer Res
, vol.62
, Issue.23
, pp. 6997-7000
-
-
Brose, M.S.1
Volpe, P.2
Feldman, M.3
-
33
-
-
0036654443
-
A genome-based strategy uncovers frequent BRAF mutations in melanoma
-
Jul;
-
Pollock PM, Meltzer PS. A genome-based strategy uncovers frequent BRAF mutations in melanoma. Cancer Cell 2002 Jul; 2 (1): 5-7
-
(2002)
Cancer Cell
, vol.2
, Issue.1
, pp. 5-7
-
-
Pollock, P.M.1
Meltzer, P.S.2
-
34
-
-
0037442752
-
Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation
-
Feb 15;
-
Satyamoorthy K, Li G, Gerrero MR, et al. Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation. Cancer Res 2003 Feb 15; 63 (4): 756-9
-
(2003)
Cancer Res
, vol.63
, Issue.4
, pp. 756-759
-
-
Satyamoorthy, K.1
Li, G.2
Gerrero, M.R.3
-
35
-
-
0042743826
-
BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma
-
Jul 15;
-
Dong J, Phelps RG, Qiao R, et al. BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma. Cancer Res 2003 Jul 15; 63 (14): 3883-5
-
(2003)
Cancer Res
, vol.63
, Issue.14
, pp. 3883-3885
-
-
Dong, J.1
Phelps, R.G.2
Qiao, R.3
-
36
-
-
33745925864
-
BRAF somatic mutations in malignant melanoma and melanocytic naevi
-
Apr;
-
Thomas NE. BRAF somatic mutations in malignant melanoma and melanocytic naevi. Melanoma Res 2006 Apr; 16 (2): 97-103
-
(2006)
Melanoma Res
, vol.16
, Issue.2
, pp. 97-103
-
-
Thomas, N.E.1
-
37
-
-
0348223934
-
NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression
-
Dec 15;
-
Omholt K, Platz A, Kanter L, et al. NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression. Clin Cancer Res 2003 Dec 15; 9 (17): 6483-8
-
(2003)
Clin Cancer Res
, vol.9
, Issue.17
, pp. 6483-6488
-
-
Omholt, K.1
Platz, A.2
Kanter, L.3
-
38
-
-
33746263912
-
BRAF and NRAS mutations in melanoma and melanocytic nevi
-
Aug;
-
Poynter JN, Elder JT, Fullen DR, et al. BRAF and NRAS mutations in melanoma and melanocytic nevi. Melanoma Res 2006 Aug; 16 (4): 267-73
-
(2006)
Melanoma Res
, vol.16
, Issue.4
, pp. 267-273
-
-
Poynter, J.N.1
Elder, J.T.2
Fullen, D.R.3
-
39
-
-
33845726945
-
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations
-
Jan;
-
Bauer J, Curtin JA, Pinkel D, et al. Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations. J Invest Dermatol 2007 Jan; 127 (1): 179-82
-
(2007)
J Invest Dermatol
, vol.127
, Issue.1
, pp. 179-182
-
-
Bauer, J.1
Curtin, J.A.2
Pinkel, D.3
-
40
-
-
0031589485
-
Genetic alterations of p16INK4a and p53 genes in sporadic dysplastic nevus
-
Aug 28;
-
Lee JY, Dong SM, Shin MS, et al. Genetic alterations of p16INK4a and p53 genes in sporadic dysplastic nevus. Biochem Biophys Res Commun 1997 Aug 28; 237 (3): 667-72
-
(1997)
Biochem Biophys Res Commun
, vol.237
, Issue.3
, pp. 667-672
-
-
Lee, J.Y.1
Dong, S.M.2
Shin, M.S.3
-
41
-
-
0031909301
-
Allelic deletion at chromosome 9p21(p16) and 17p13(p53) in microdissected sporadic dysplastic nevus
-
Feb;
-
Park WS, Vortmeyer AO, Pack S, et al. Allelic deletion at chromosome 9p21(p16) and 17p13(p53) in microdissected sporadic dysplastic nevus. Hum Pathol 1998 Feb; 29 (2): 127-30
-
(1998)
Hum Pathol
, vol.29
, Issue.2
, pp. 127-130
-
-
Park, W.S.1
Vortmeyer, A.O.2
Pack, S.3
-
42
-
-
26444451975
-
Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B
-
Apr 8;
-
Soto JL, Cabrera CM, Serrano S, et al. Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B. BMC Cancer 2005 Apr 8; 5 (1): 36
-
(2005)
BMC Cancer
, vol.5
, Issue.1
, pp. 36
-
-
Soto, J.L.1
Cabrera, C.M.2
Serrano, S.3
-
43
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Jan 11;
-
Soengas MS, Capodieci P, Polsky D, et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 2001 Jan 11; 409 (6817): 207-11
-
(2001)
Nature
, vol.409
, Issue.6817
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
-
45
-
-
5044237664
-
Reduced Apaf-1 expression in human cutaneous melanomas
-
Sep 13;
-
Dai DL, Martinka M, Bush JA, et al. Reduced Apaf-1 expression in human cutaneous melanomas. Br J Cancer 2004 Sep 13; 91 (6): 1089-95
-
(2004)
Br J Cancer
, vol.91
, Issue.6
, pp. 1089-1095
-
-
Dai, D.L.1
Martinka, M.2
Bush, J.A.3
-
46
-
-
10744220426
-
Analysis of APAF-1 expression in human cutaneous melanoma progression
-
Feb;
-
Baldi A, Santini D, Russo P, et al. Analysis of APAF-1 expression in human cutaneous melanoma progression. Exp Dermatol 2004 Feb; 13 (2): 93-7
-
(2004)
Exp Dermatol
, vol.13
, Issue.2
, pp. 93-97
-
-
Baldi, A.1
Santini, D.2
Russo, P.3
-
47
-
-
12844255773
-
Decreased expression of Apaf-1 with progression of melanoma
-
Feb;
-
Mustika R, Budiyanto A, Nishigori C, et al. Decreased expression of Apaf-1 with progression of melanoma. Pigment Cell Res 2005 Feb; 18 (1): 59-62
-
(2005)
Pigment Cell Res
, vol.18
, Issue.1
, pp. 59-62
-
-
Mustika, R.1
Budiyanto, A.2
Nishigori, C.3
-
48
-
-
33645080439
-
Apaf-1 expression in human cutaneous melanoma progression and in pigmented nevi
-
Feb;
-
Niedojadlo K, Labedzka K, Lada E, et al. Apaf-1 expression in human cutaneous melanoma progression and in pigmented nevi. Pigment Cell Res 2006 Feb; 19 (1): 43-50
-
(2006)
Pigment Cell Res
, vol.19
, Issue.1
, pp. 43-50
-
-
Niedojadlo, K.1
Labedzka, K.2
Lada, E.3
-
49
-
-
33744993408
-
APAF-1 signaling in human melanoma
-
Jul 18;
-
Anichini A, Mortarini R, Sensi M, et al. APAF-1 signaling in human melanoma. Cancer Lett 2006 Jul 18; 238 (2): 168-79
-
(2006)
Cancer Lett
, vol.238
, Issue.2
, pp. 168-179
-
-
Anichini, A.1
Mortarini, R.2
Sensi, M.3
-
50
-
-
18644380911
-
Roles of activated Src and STAT3 signaling in melanoma tumor cell growth
-
Oct 10;
-
Niu G, Bowman T, Huang M, et al. Roles of activated Src and STAT3 signaling in melanoma tumor cell growth. Oncogene 2002 Oct 10; 21 (46): 7001-10
-
(2002)
Oncogene
, vol.21
, Issue.46
, pp. 7001-7010
-
-
Niu, G.1
Bowman, T.2
Huang, M.3
-
51
-
-
20144376844
-
STAT3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects
-
Apr 1;
-
Burdelya L, Kujawski M, Niu G, et al. STAT3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects. J Immunol 2005 Apr 1; 174 (7): 3925-31
-
(2005)
J Immunol
, vol.174
, Issue.7
, pp. 3925-3931
-
-
Burdelya, L.1
Kujawski, M.2
Niu, G.3
-
52
-
-
21544473172
-
Targeting STAT3 affects melanoma on multiple fronts
-
Jun;
-
Kortylewski M, Jove R, Yu H. Targeting STAT3 affects melanoma on multiple fronts. Cancer Metastasis Rev 2005 Jun; 24 (2): 315-27
-
(2005)
Cancer Metastasis Rev
, vol.24
, Issue.2
, pp. 315-327
-
-
Kortylewski, M.1
Jove, R.2
Yu, H.3
-
53
-
-
33748802513
-
STAT5 phosphorylation in malignant melanoma is important for survival and is mediated through SRC and JAK1 kinases
-
Oct;
-
Mirmohammadsadegh A, Hassan M, Bardenheuer W, et al. STAT5 phosphorylation in malignant melanoma is important for survival and is mediated through SRC and JAK1 kinases. J Invest Dermatol 2006 Oct; 126 (10): 2272-80
-
(2006)
J Invest Dermatol
, vol.126
, Issue.10
, pp. 2272-2280
-
-
Mirmohammadsadegh, A.1
Hassan, M.2
Bardenheuer, W.3
-
54
-
-
0030712998
-
Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma
-
Nov 7;
-
Wong LH, Krauer KG, Hatzinisiriou I, et al. Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma. J Biol Chem 1997 Nov 7; 272 (45): 28779-85
-
(1997)
J Biol Chem
, vol.272
, Issue.45
, pp. 28779-28785
-
-
Wong, L.H.1
Krauer, K.G.2
Hatzinisiriou, I.3
-
55
-
-
0033973215
-
Defective Jak-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha
-
Mar 1;
-
Pansky A, Hildebrand P, Fasler-Kan E, et al. Defective Jak-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha. Int J Cancer 2000 Mar 1; 85 (5): 720-5
-
(2000)
Int J Cancer
, vol.85
, Issue.5
, pp. 720-725
-
-
Pansky, A.1
Hildebrand, P.2
Fasler-Kan, E.3
-
56
-
-
0642364433
-
Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation
-
Sep;
-
Kovarik J, Boudny V, Kocak I, et al. Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. Int J Mol Med 2003 Sep; 12 (3): 335-40
-
(2003)
Int J Mol Med
, vol.12
, Issue.3
, pp. 335-340
-
-
Kovarik, J.1
Boudny, V.2
Kocak, I.3
-
57
-
-
0042324670
-
Interferon inducibility of STAT 1 activation and its prognostic significance in melanoma patients
-
Boudny V, Kocak I, Lauerova L, et al. Interferon inducibility of STAT 1 activation and its prognostic significance in melanoma patients. Folia Biol (Praha) 2003; 49 (4): 142-6
-
(2003)
Folia Biol (Praha)
, vol.49
, Issue.4
, pp. 142-146
-
-
Boudny, V.1
Kocak, I.2
Lauerova, L.3
-
58
-
-
23044463075
-
Lack of STAT 1 phosphorylation at TYR 701 by IFNgamma correlates with disease outcome in melanoma patients
-
Boudny V, Dusek L, Adamkova L, et al. Lack of STAT 1 phosphorylation at TYR 701 by IFNgamma correlates with disease outcome in melanoma patients. Neoplasma 2005; 52 (4): 330-7
-
(2005)
Neoplasma
, vol.52
, Issue.4
, pp. 330-337
-
-
Boudny, V.1
Dusek, L.2
Adamkova, L.3
-
59
-
-
0028085975
-
Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus
-
Sep;
-
Kamb A, Shattuck-Eidens D, Eeles R, et al. Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nat Genet 1994 Sep; 8 (1): 23-6
-
(1994)
Nat Genet
, vol.8
, Issue.1
, pp. 23-26
-
-
Kamb, A.1
Shattuck-Eidens, D.2
Eeles, R.3
-
60
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Apr 15;
-
Kamb A, Gruis NA, Weaver-Feldhaus J, et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science 1994 Apr 15; 264 (5157): 436-40
-
(1994)
Science
, vol.264
, Issue.5157
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
-
61
-
-
0027958821
-
Localization of a putative tumor suppressor gene by using homozygous deletions in melanomas
-
Aug 2;
-
Weaver-Feldhaus J, Gruis NA, Neuhausen S, et al. Localization of a putative tumor suppressor gene by using homozygous deletions in melanomas. Proc Natl Acad Sci U S A 1994 Aug 2; 91 (16): 7563-7
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.16
, pp. 7563-7567
-
-
Weaver-Feldhaus, J.1
Gruis, N.A.2
Neuhausen, S.3
-
62
-
-
0028295583
-
Loss of heterozygosity and homozygous deletions on 9p21-22 in melanoma
-
Holland EA, Beaton SC, Edwards BG, et al. Loss of heterozygosity and homozygous deletions on 9p21-22 in melanoma. Oncogene 1994; 9: 1361-5
-
(1994)
Oncogene
, vol.9
, pp. 1361-1365
-
-
Holland, E.A.1
Beaton, S.C.2
Edwards, B.G.3
-
63
-
-
0029658666
-
Loss of the p16INK4a and p15INK4b genes, as well as neighboring 9p21 markers, in sporadic melanoma
-
Nov 1;
-
Flores JF, Walker GJ, Glendening JM, et al. Loss of the p16INK4a and p15INK4b genes, as well as neighboring 9p21 markers, in sporadic melanoma. Cancer Res 1996 Nov 1; 56 (21): 5023-32
-
(1996)
Cancer Res
, vol.56
, Issue.21
, pp. 5023-5032
-
-
Flores, J.F.1
Walker, G.J.2
Glendening, J.M.3
-
64
-
-
0029664945
-
Infrequent mutation of p16INK4 in sporadic melanoma
-
Sep;
-
Healy E, Sikkink S, Rees JL. Infrequent mutation of p16INK4 in sporadic melanoma. J Invest Dermatol 1996 Sep; 107 (3): 318-21
-
(1996)
J Invest Dermatol
, vol.107
, Issue.3
, pp. 318-321
-
-
Healy, E.1
Sikkink, S.2
Rees, J.L.3
-
65
-
-
0031594829
-
Homozygous deletion of the p16INK4a and the p15INK4b tumour suppressor genes in a subset of human sporadic cutaneous malignant melanoma
-
Jan;
-
Wagner SN, Wagner C, Briedigkeit L, et al. Homozygous deletion of the p16INK4a and the p15INK4b tumour suppressor genes in a subset of human sporadic cutaneous malignant melanoma. Br J Dermatol 1998 Jan; 138 (1): 13-21
-
(1998)
Br J Dermatol
, vol.138
, Issue.1
, pp. 13-21
-
-
Wagner, S.N.1
Wagner, C.2
Briedigkeit, L.3
-
66
-
-
0031894534
-
Molecular genetics of familial cutaneous melanoma
-
Feb;
-
Haluska FG, Hodi FS. Molecular genetics of familial cutaneous melanoma. J Clin Oncol 1998 Feb; 16 (2): 670-82
-
(1998)
J Clin Oncol
, vol.16
, Issue.2
, pp. 670-682
-
-
Haluska, F.G.1
Hodi, F.S.2
-
67
-
-
0033560166
-
p16INK4a inactivation is not frequent in uncultured sporadic primary cutaneous melanoma
-
Apr 15;
-
Fujimoto A, Morita R, Hatta N, et al. p16INK4a inactivation is not frequent in uncultured sporadic primary cutaneous melanoma. Oncogene 1999 Apr 15; 18 (15): 2527-32
-
(1999)
Oncogene
, vol.18
, Issue.15
, pp. 2527-2532
-
-
Fujimoto, A.1
Morita, R.2
Hatta, N.3
-
68
-
-
0032794625
-
Loss of heterozygosity at chromosome 9p21 (INK4-p14ARF locus): Homozygous deletions and mutations in the p16 and p14ARF genes in sporadic primary melanomas
-
Apr;
-
Kumar R, Smeds J, Lundh Rozell B, et al. Loss of heterozygosity at chromosome 9p21 (INK4-p14ARF locus): homozygous deletions and mutations in the p16 and p14ARF genes in sporadic primary melanomas. Melanoma Res 1999 Apr; 9 (2): 138-47
-
(1999)
Melanoma Res
, vol.9
, Issue.2
, pp. 138-147
-
-
Kumar, R.1
Smeds, J.2
Lundh Rozell, B.3
-
69
-
-
17744386133
-
Definition of the role of chromosome 9p21 in sporadic melanoma through genetic analysis of primary tumours and their metastases: The Melanoma Cooperative Group
-
Dec;
-
Imieri G, Cossu A, Ascierto PA, et al. Definition of the role of chromosome 9p21 in sporadic melanoma through genetic analysis of primary tumours and their metastases: the Melanoma Cooperative Group. Br J Cancer 2000 Dec; 83 (12): 1707-14
-
(2000)
Br J Cancer
, vol.83
, Issue.12
, pp. 1707-1714
-
-
Imieri, G.1
Cossu, A.2
Ascierto, P.A.3
-
70
-
-
0034918766
-
Comprehensive analysis of 112 melanocytic skin lesions demonstrates microsatellite instability in melanomas and dysplastic nevi, but not in benign nevi
-
Aug;
-
Hussein MR, Sun M, Tuthill RJ, et al. Comprehensive analysis of 112 melanocytic skin lesions demonstrates microsatellite instability in melanomas and dysplastic nevi, but not in benign nevi. J Cutan Pathol 2001 Aug; 28 (7): 343-50
-
(2001)
J Cutan Pathol
, vol.28
, Issue.7
, pp. 343-350
-
-
Hussein, M.R.1
Sun, M.2
Tuthill, R.J.3
-
71
-
-
0036050753
-
Loss of heterozygosity and microsatellite instability in acquired melanocytic nevi: Towards a molecular definition of the dysplastic nevus
-
Rubben A, Bogdan I, Grussendorf-Conen EI, et al. Loss of heterozygosity and microsatellite instability in acquired melanocytic nevi: towards a molecular definition of the dysplastic nevus. Recent Results Cancer Res 2002; 160: 100-10
-
(2002)
Recent Results Cancer Res
, vol.160
, pp. 100-110
-
-
Rubben, A.1
Bogdan, I.2
Grussendorf-Conen, E.I.3
-
72
-
-
20544434596
-
-
Casorzo L, Luzzi C, Nardacchione A, et al. Fluorescence in situ hybridization (FISH) evaluation of chromosomes 6, 7, 9 and 10 throughout human melanocytic tumorigenesis. Melanoma Res 2005 Jun; 15 (3): 155-60
-
Casorzo L, Luzzi C, Nardacchione A, et al. Fluorescence in situ hybridization (FISH) evaluation of chromosomes 6, 7, 9 and 10 throughout human melanocytic tumorigenesis. Melanoma Res 2005 Jun; 15 (3): 155-60
-
-
-
-
73
-
-
0036241674
-
Loss of heterozygosity, microsatellite instability, and mismatch repair protein alterations in the radial growth phase of cutaneous malignant melanomas
-
May;
-
Hussein MR, Sun M, Roggero E, et al. Loss of heterozygosity, microsatellite instability, and mismatch repair protein alterations in the radial growth phase of cutaneous malignant melanomas. Mol Carcinog 2002 May; 34 (1): 35-44
-
(2002)
Mol Carcinog
, vol.34
, Issue.1
, pp. 35-44
-
-
Hussein, M.R.1
Sun, M.2
Roggero, E.3
-
74
-
-
0032560083
-
-
Matsuoka M, Tani K, Asano S. Interferon-alpha-induced G1 phase arrest through up-regulated expression of CDK inhibitors, p19Ink4D and p21Cip1 in mouse macrophages. Oncogene 1998 Apr 23; 16 (16): 2075-86
-
Matsuoka M, Tani K, Asano S. Interferon-alpha-induced G1 phase arrest through up-regulated expression of CDK inhibitors, p19Ink4D and p21Cip1 in mouse macrophages. Oncogene 1998 Apr 23; 16 (16): 2075-86
-
-
-
-
75
-
-
0033529122
-
Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins
-
May 6;
-
Sangfelt O, Erickson S, Castro J, et al. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins. Oncogene 1999 May 6; 18 (18): 2798-810
-
(1999)
Oncogene
, vol.18
, Issue.18
, pp. 2798-2810
-
-
Sangfelt, O.1
Erickson, S.2
Castro, J.3
-
77
-
-
18844457095
-
Mechanisms of type-I- and type-II-interferon-mediated signalling
-
May;
-
Platanias LC. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol 2005 May; 5 (5): 375-86
-
(2005)
Nat Rev Immunol
, vol.5
, Issue.5
, pp. 375-386
-
-
Platanias, L.C.1
-
78
-
-
33645816781
-
Systematic review of systemic adjuvant therapy for patients at high risk for recurrent melanoma
-
Apr 1;
-
Verma S, Quirt I, McCready D, et al. Systematic review of systemic adjuvant therapy for patients at high risk for recurrent melanoma. Cancer 2006 Apr 1; 106 (7): 1431-42
-
(2006)
Cancer
, vol.106
, Issue.7
, pp. 1431-1442
-
-
Verma, S.1
Quirt, I.2
McCready, D.3
-
79
-
-
32644454916
-
Prognostic significance of autoimmunity during treatment of melanoma with interferon
-
Feb 16;
-
Gogas H, Ioannovich J, Dafni U, et al. Prognostic significance of autoimmunity during treatment of melanoma with interferon. N Engl J Med 2006 Feb 16; 354 (7): 709-18
-
(2006)
N Engl J Med
, vol.354
, Issue.7
, pp. 709-718
-
-
Gogas, H.1
Ioannovich, J.2
Dafni, U.3
-
80
-
-
0030964344
-
Screening of germline mutations in the CDKN2A and CDKN2B genes in Swedish families with hereditary cutaneous melanoma
-
May 21;
-
Platz A, Hansson J, Mansson-Brahme E, et al. Screening of germline mutations in the CDKN2A and CDKN2B genes in Swedish families with hereditary cutaneous melanoma. J Natl Cancer Inst 1997 May 21; 89 (10): 697-702
-
(1997)
J Natl Cancer Inst
, vol.89
, Issue.10
, pp. 697-702
-
-
Platz, A.1
Hansson, J.2
Mansson-Brahme, E.3
-
81
-
-
0035860135
-
CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: Functional characterization of a novel CDKN2A germ line mutation
-
Sep 14;
-
Della Torre G, Pasini B, Frigerio S, et al. CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: functional characterization of a novel CDKN2A germ line mutation. Br J Cancer 2001 Sep 14; 85 (6): 836-44
-
(2001)
Br J Cancer
, vol.85
, Issue.6
, pp. 836-844
-
-
Della Torre, G.1
Pasini, B.2
Frigerio, S.3
-
83
-
-
0026464014
-
Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia
-
Oct;
-
Olopade OI, Bohlander SK, Pomykala H, et al. Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. Genomics 1992 Oct; 14 (2): 437-43
-
(1992)
Genomics
, vol.14
, Issue.2
, pp. 437-443
-
-
Olopade, O.I.1
Bohlander, S.K.2
Pomykala, H.3
-
84
-
-
0027980347
-
Structure of the human type-I interferon gene cluster determined from a YAC clone contig
-
Aug;
-
Diaz MO, Pomykala HM, Bohlander SK, et al. Structure of the human type-I interferon gene cluster determined from a YAC clone contig. Genomics 1994 Aug; 22 (3): 540-52
-
(1994)
Genomics
, vol.22
, Issue.3
, pp. 540-552
-
-
Diaz, M.O.1
Pomykala, H.M.2
Bohlander, S.K.3
-
85
-
-
0032980308
-
The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer
-
Tsihlias J, Kapusta L, Slingerland J. The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. Annu Rev Med 1999; 50: 401-23
-
(1999)
Annu Rev Med
, vol.50
, pp. 401-423
-
-
Tsihlias, J.1
Kapusta, L.2
Slingerland, J.3
-
86
-
-
0007002082
-
Sensitivity to extrinsically supplied interferon and the endogenous expression of interferon in melanoma cell lines
-
Oct;
-
Hanson C, Kopf I, Weijdegard B, et al. Sensitivity to extrinsically supplied interferon and the endogenous expression of interferon in melanoma cell lines. Melanoma Res 1999 Oct; 9 (5): 451-6
-
(1999)
Melanoma Res
, vol.9
, Issue.5
, pp. 451-456
-
-
Hanson, C.1
Kopf, I.2
Weijdegard, B.3
-
87
-
-
0026654568
-
Correlation between interferon (IFN) alpha resistance and deletion of the IFN alpha/beta genes in acute leukemia cell lines suggests selection against the IFN system
-
Aug 1;
-
Colamonici OR, Domanski P, Platanias LC, et al. Correlation between interferon (IFN) alpha resistance and deletion of the IFN alpha/beta genes in acute leukemia cell lines suggests selection against the IFN system. Blood 1992 Aug 1; 80 (3): 744-9
-
(1992)
Blood
, vol.80
, Issue.3
, pp. 744-749
-
-
Colamonici, O.R.1
Domanski, P.2
Platanias, L.C.3
-
88
-
-
0021038111
-
Effects of cloned human leukocyte interferons in the human tumor stem cell assay
-
Salmon SE, Durie BG, Young L, et al. Effects of cloned human leukocyte interferons in the human tumor stem cell assay. J Clin Oncol 1983; 1 (3): 217-25
-
(1983)
J Clin Oncol
, vol.1
, Issue.3
, pp. 217-225
-
-
Salmon, S.E.1
Durie, B.G.2
Young, L.3
-
89
-
-
0022885397
-
Antiproliferative effects of interferons on human melanoma cells in the human tumor colony-forming assay
-
Schiller JH, Willson JK, Bittner G, et al. Antiproliferative effects of interferons on human melanoma cells in the human tumor colony-forming assay. J Interferon Res 1986; 6 (6): 615-25
-
(1986)
J Interferon Res
, vol.6
, Issue.6
, pp. 615-625
-
-
Schiller, J.H.1
Willson, J.K.2
Bittner, G.3
-
90
-
-
0021342194
-
Human tumor colony assay and chemosensitivity testing
-
Salmon SE. Human tumor colony assay and chemosensitivity testing. Cancer Treat Rep 1984; 68 (1): 117-25
-
(1984)
Cancer Treat Rep
, vol.68
, Issue.1
, pp. 117-125
-
-
Salmon, S.E.1
-
91
-
-
0021687248
-
Relation of in vitro colony survival to clinical response in a prospective trial of single-agent chemotherapy for metastatic melanoma
-
Meyskens Jr FL, Loescher L, Moon TE, et al. Relation of in vitro colony survival to clinical response in a prospective trial of single-agent chemotherapy for metastatic melanoma. J Clin Oncol 1984; 2: 1223-8
-
(1984)
J Clin Oncol
, vol.2
, pp. 1223-1228
-
-
Meyskens Jr, F.L.1
Loescher, L.2
Moon, T.E.3
-
92
-
-
0028324596
-
Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes
-
Mar 15;
-
Mattei S, Colombo MP, Melani C, et al. Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes. Int J Cancer 1994 Mar 15; 56 (6): 853-7
-
(1994)
Int J Cancer
, vol.56
, Issue.6
, pp. 853-857
-
-
Mattei, S.1
Colombo, M.P.2
Melani, C.3
-
93
-
-
0029090447
-
Interferon system defects in human malignant melanoma
-
Sep 15;
-
Linge C, Gewert D, Rossmann C, et al. Interferon system defects in human malignant melanoma. Cancer Res 1995 Sep 15; 55 (18): 4099-104
-
(1995)
Cancer Res
, vol.55
, Issue.18
, pp. 4099-4104
-
-
Linge, C.1
Gewert, D.2
Rossmann, C.3
-
94
-
-
18344393309
-
The prevalence of interferon-alpha transcrip tion defects in malignant melanoma
-
Apr;
-
Price KL, Herlyn M, Dent CL, et al. The prevalence of interferon-alpha transcrip tion defects in malignant melanoma. Melanoma Res 2005 Apr; 15 (2): 91-8
-
(2005)
Melanoma Res
, vol.15
, Issue.2
, pp. 91-98
-
-
Price, K.L.1
Herlyn, M.2
Dent, C.L.3
-
95
-
-
3442894137
-
Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas
-
Aug 1;
-
Hoek K, Rimm DL, Williams KR, et al. Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res 2004 Aug 1; 64 (15): 5270-82
-
(2004)
Cancer Res
, vol.64
, Issue.15
, pp. 5270-5282
-
-
Hoek, K.1
Rimm, D.L.2
Williams, K.R.3
-
96
-
-
0036178266
-
Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback
-
Jan;
-
Levy DE, Marie I, Smith E, et al. Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback. J Interferon Cytokine Res 2002 Jan; 22 (1): 87-93
-
(2002)
J Interferon Cytokine Res
, vol.22
, Issue.1
, pp. 87-93
-
-
Levy, D.E.1
Marie, I.2
Smith, E.3
-
97
-
-
0342646934
-
Autocrine and paracrine regulation by cytokines and growth factors in melanoma
-
Jun;
-
Lazar-Molnar E, Hegyesi H, Toth S, et al. Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine 2000 Jun; 12 (6): 547-54
-
(2000)
Cytokine
, vol.12
, Issue.6
, pp. 547-554
-
-
Lazar-Molnar, E.1
Hegyesi, H.2
Toth, S.3
-
98
-
-
0027396955
-
Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression
-
Mar;
-
Lu C, Kerbel RS. Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression. J Cell Biol 1993 Mar; 120 (5): 1281-8
-
(1993)
J Cell Biol
, vol.120
, Issue.5
, pp. 1281-1288
-
-
Lu, C.1
Kerbel, R.S.2
-
99
-
-
21344435775
-
Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer
-
Jun;
-
Haura EB, Turkson J, Jove R. Mechanisms of disease: insights into the emerging role of signal transducers and activators of transcription in cancer. Nat Clin Pract Oncol 2005 Jun; 2 (6): 315-24
-
(2005)
Nat Clin Pract Oncol
, vol.2
, Issue.6
, pp. 315-324
-
-
Haura, E.B.1
Turkson, J.2
Jove, R.3
-
100
-
-
23844503025
-
Role of STAT3 in regulating p53 expression and function
-
Sep;
-
Niu G, Wright KL, Ma Y, et al. Role of STAT3 in regulating p53 expression and function. Mol Cell Biol 2005 Sep; 25 (17): 7432-40
-
(2005)
Mol Cell Biol
, vol.25
, Issue.17
, pp. 7432-7440
-
-
Niu, G.1
Wright, K.L.2
Ma, Y.3
-
101
-
-
28844508928
-
The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation
-
Dec;
-
Bedogni B, Welford SM, Cassarino DS, et al. The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation. Cancer Cell 2005 Dec; 8 (6): 443-54
-
(2005)
Cancer Cell
, vol.8
, Issue.6
, pp. 443-454
-
-
Bedogni, B.1
Welford, S.M.2
Cassarino, D.S.3
-
102
-
-
33745003285
-
Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB
-
Jun 15;
-
Frede S, Stockmann C, Freitag P, et al. Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB. Biochem J 2006 Jun 15; 396 (3): 517-27
-
(2006)
Biochem J
, vol.396
, Issue.3
, pp. 517-527
-
-
Frede, S.1
Stockmann, C.2
Freitag, P.3
-
103
-
-
18844444774
-
HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
-
Apr 28;
-
Gray MJ, Zhang J, Ellis LM, et al. HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene 2005 Apr 28; 24 (19): 3110-20
-
(2005)
Oncogene
, vol.24
, Issue.19
, pp. 3110-3120
-
-
Gray, M.J.1
Zhang, J.2
Ellis, L.M.3
-
104
-
-
24644457736
-
Targeting STAT3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
-
Aug 25;
-
Xu Q, Briggs J, Park S, et al. Targeting STAT3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways. Oncogene 2005 Aug 25; 24 (36): 5552-60
-
(2005)
Oncogene
, vol.24
, Issue.36
, pp. 5552-5560
-
-
Xu, Q.1
Briggs, J.2
Park, S.3
-
105
-
-
0033597715
-
Fetal anemia and apoptosis of red cell progenitors in STAT5a -/- 5b -/- mice: A direct role for STAT5 in Bcl-X(L) induction
-
Socolovsky M, Fallon AEJ, Wang S, et al. Fetal anemia and apoptosis of red cell progenitors in STAT5a -/- 5b -/- mice: a direct role for STAT5 in Bcl-X(L) induction. Cell 1999; 98: 181-91
-
(1999)
Cell
, vol.98
, pp. 181-191
-
-
Socolovsky, M.1
Fallon, A.E.J.2
Wang, S.3
-
106
-
-
0026742542
-
Antiproliferative potencies of interferons on melanoma cell lines and xenografts: Higher efficacy of interferon beta
-
Johns TG, Mackay IR, Callister KA, et al. Antiproliferative potencies of interferons on melanoma cell lines and xenografts: higher efficacy of interferon beta. J Natl Cancer Inst 1992; 84 (15): 1185-90
-
(1992)
J Natl Cancer Inst
, vol.84
, Issue.15
, pp. 1185-1190
-
-
Johns, T.G.1
Mackay, I.R.2
Callister, K.A.3
-
107
-
-
0027751533
-
A colourimetric dye assay to detect antiviral activity of interferons: Sensitivity for measuring cellular responsiveness to interferons
-
Wines BD, Choe CC, Hatzinisiriou I, et al. A colourimetric dye assay to detect antiviral activity of interferons: sensitivity for measuring cellular responsiveness to interferons. Biochem Mol Biol Int 1993; 31 (6): 1111-20
-
(1993)
Biochem Mol Biol Int
, vol.31
, Issue.6
, pp. 1111-1120
-
-
Wines, B.D.1
Choe, C.C.2
Hatzinisiriou, I.3
-
108
-
-
0028955664
-
Resistance of melanoma cell lines to interferons correlates with reduction of IFN-induced tyrosine phosphorylation: Induction of the anti-viral state by IFN is prevented by tyrosine kinase inhibitors
-
Ralph SJ, Wines BD, Payne MJ, et al. Resistance of melanoma cell lines to interferons correlates with reduction of IFN-induced tyrosine phosphorylation: induction of the anti-viral state by IFN is prevented by tyrosine kinase inhibitors. J Immunol 1995; 154: 2248-56
-
(1995)
J Immunol
, vol.154
, pp. 2248-2256
-
-
Ralph, S.J.1
Wines, B.D.2
Payne, M.J.3
-
109
-
-
0032102991
-
IFN-gamma priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs
-
Wong LH, Hatzinisiriou I, Devenish RJ, et al. IFN-gamma priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs. J Immunol 1998; 160: 5475-84
-
(1998)
J Immunol
, vol.160
, pp. 5475-5484
-
-
Wong, L.H.1
Hatzinisiriou, I.2
Devenish, R.J.3
-
110
-
-
0036016562
-
Resistance to interferons in melanoma cells does not correlate with the expression or activation of signal transducer and activator of transcription 1 (STAT1)
-
Chawla-Sarkar M, Leaman DW, Jacobs BS, et al. Resistance to interferons in melanoma cells does not correlate with the expression or activation of signal transducer and activator of transcription 1 (STAT1). J Interferon Cytokine Res 2002; 22: 603-13
-
(2002)
J Interferon Cytokine Res
, vol.22
, pp. 603-613
-
-
Chawla-Sarkar, M.1
Leaman, D.W.2
Jacobs, B.S.3
-
111
-
-
0037205415
-
-
Wong LH, Sim H, Chatterjee-Kishore M, et al. Isolation and characterization of a human STAT1 gene regulatory element: inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1. J Biol Chem 2002 May 31; 277 (22): 19408-17
-
Wong LH, Sim H, Chatterjee-Kishore M, et al. Isolation and characterization of a human STAT1 gene regulatory element: inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1. J Biol Chem 2002 May 31; 277 (22): 19408-17
-
-
-
-
112
-
-
0029964303
-
Why do so many cancer patients fail to respond to interferon therapy?
-
Einhorn S, Grander D. Why do so many cancer patients fail to respond to interferon therapy? J Interferon Cytokine Res 1996; 16: 275-81
-
(1996)
J Interferon Cytokine Res
, vol.16
, pp. 275-281
-
-
Einhorn, S.1
Grander, D.2
-
113
-
-
0242412335
-
Reprogramming of IL-10 activity and signaling by IFN-gamma
-
Nov 15;
-
Herrero C, Hu X, Li WP, et al. Reprogramming of IL-10 activity and signaling by IFN-gamma. J Immunol 2003 Nov 15; 171 (10): 5034-41
-
(2003)
J Immunol
, vol.171
, Issue.10
, pp. 5034-5041
-
-
Herrero, C.1
Hu, X.2
Li, W.P.3
-
114
-
-
31444433983
-
The role of regulatory T lymphocytes in the induced immune response mediated by biological vaccines
-
Lopez M, Aguilera R, Perez C, et al. The role of regulatory T lymphocytes in the induced immune response mediated by biological vaccines. Immunobiology 2006; 211 (1-2): 127-36
-
(2006)
Immunobiology
, vol.211
, Issue.1-2
, pp. 127-136
-
-
Lopez, M.1
Aguilera, R.2
Perez, C.3
-
115
-
-
11144357779
-
Regulation of the innate and adaptive immune responses by STAT-3 signaling in tumor cells
-
Jan;
-
Wang T, Niu G, Kortylewski M, et al. Regulation of the innate and adaptive immune responses by STAT-3 signaling in tumor cells. Nat Med 2004 Jan; 10 (1): 48-54
-
(2004)
Nat Med
, vol.10
, Issue.1
, pp. 48-54
-
-
Wang, T.1
Niu, G.2
Kortylewski, M.3
-
116
-
-
24344460338
-
Melanoma skews dendritic cells to facilitate a T helper 2 profile
-
Aug;
-
McCarter M, Clarke J, Richter D, et al. Melanoma skews dendritic cells to facilitate a T helper 2 profile. Surgery 2005 Aug; 138 (2): 321-8
-
(2005)
Surgery
, vol.138
, Issue.2
, pp. 321-328
-
-
McCarter, M.1
Clarke, J.2
Richter, D.3
-
117
-
-
0030586077
-
Endogenous interferon-gamma acts directly on tumor cells in vivo to suppress growth
-
Doherty GM, Tsung K, McCluskey B, et al. Endogenous interferon-gamma acts directly on tumor cells in vivo to suppress growth. J Surg Res 1996; 64: 68-74
-
(1996)
J Surg Res
, vol.64
, pp. 68-74
-
-
Doherty, G.M.1
Tsung, K.2
McCluskey, B.3
-
118
-
-
0033034333
-
Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: Association with disease progression
-
Kageshita T, Hirai S, Ono T, et al. Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: association with disease progression. Am J Pathol 1999; 154: 745-54
-
(1999)
Am J Pathol
, vol.154
, pp. 745-754
-
-
Kageshita, T.1
Hirai, S.2
Ono, T.3
-
119
-
-
4744355872
-
Escape from immunotherapy: Possible mechanisms that influence tumor regression/progression
-
Oct;
-
Ahmad M, Rees RC, Ali SA. Escape from immunotherapy: possible mechanisms that influence tumor regression/progression. Cancer Immunol Immunother 2004 Oct; 53 (10): 844-54
-
(2004)
Cancer Immunol Immunother
, vol.53
, Issue.10
, pp. 844-854
-
-
Ahmad, M.1
Rees, R.C.2
Ali, S.A.3
-
120
-
-
30344438861
-
Strategies of tumor immune evasion
-
Seliger B. Strategies of tumor immune evasion. BioDrugs 2005; 19 (6): 347-54
-
(2005)
BioDrugs
, vol.19
, Issue.6
, pp. 347-354
-
-
Seliger, B.1
-
121
-
-
33646755569
-
Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity
-
Smyth MJ, Dunn GP, Schreiber RD. Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv Immunol 2006; 90: 1-50
-
(2006)
Adv Immunol
, vol.90
, pp. 1-50
-
-
Smyth, M.J.1
Dunn, G.P.2
Schreiber, R.D.3
-
122
-
-
24344439755
-
Loss of S100 antigenicity in metastatic melanoma
-
Sep;
-
Aisner DL, Maker A, Rosenberg SA, et al. Loss of S100 antigenicity in metastatic melanoma. Hum Pathol 2005 Sep; 36 (9): 1016-9
-
(2005)
Hum Pathol
, vol.36
, Issue.9
, pp. 1016-1019
-
-
Aisner, D.L.1
Maker, A.2
Rosenberg, S.A.3
-
123
-
-
0038010115
-
Autonomous histopathological regression of primary tumours associated with specific immune responses to cancer antigens
-
Saleh FH, Crotty KA, Hersey P, et al. Autonomous histopathological regression of primary tumours associated with specific immune responses to cancer antigens. J Pathol 2003; 200: 383-95
-
(2003)
J Pathol
, vol.200
, pp. 383-395
-
-
Saleh, F.H.1
Crotty, K.A.2
Hersey, P.3
-
124
-
-
0036852191
-
Natural selection of tumor variants in the generation of 'tumor escape' phenotypes
-
Khong HT, Restifo NP. Natural selection of tumor variants in the generation of 'tumor escape' phenotypes. Nature Immunol 2002; 3: 999-1005
-
(2002)
Nature Immunol
, vol.3
, pp. 999-1005
-
-
Khong, H.T.1
Restifo, N.P.2
-
125
-
-
18044402454
-
When magic bullets miss their mark [editorial]
-
Levitsky HI. When magic bullets miss their mark [editorial]. Blood 2001; 97: 833
-
(2001)
Blood
, vol.97
, pp. 833
-
-
Levitsky, H.I.1
-
126
-
-
1642546952
-
Enhancing CTL responses to melanoma cell vaccines in vivo: Synergistic increases obtained using IFNgamma primed and IFNbeta treated B7-1+ B16-F10 melanoma cells
-
Dec;
-
Dezfouli S, Hatzinisiriou I, Ralph SJ. Enhancing CTL responses to melanoma cell vaccines in vivo: synergistic increases obtained using IFNgamma primed and IFNbeta treated B7-1+ B16-F10 melanoma cells. Immunol Cell Biol 2003 Dec; 81 (6): 459-71
-
(2003)
Immunol Cell Biol
, vol.81
, Issue.6
, pp. 459-471
-
-
Dezfouli, S.1
Hatzinisiriou, I.2
Ralph, S.J.3
-
127
-
-
0033514923
-
Immune surveillance against a solid tumor fails because of immunological ignorance
-
Mar 2;
-
Ochsenbein AF, Klenerman P, Karrer U, et al. Immune surveillance against a solid tumor fails because of immunological ignorance. Proc Natl Acad Sci U S A 1999 Mar 2; 96 (5): 2233-8
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.5
, pp. 2233-2238
-
-
Ochsenbein, A.F.1
Klenerman, P.2
Karrer, U.3
-
128
-
-
0035963379
-
Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction
-
Jun 28;
-
Ochsenbein AF, Sierro S, Odermatt B, et al. Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction. Nature 2001 Jun 28; 411 (6841): 1058-64
-
(2001)
Nature
, vol.411
, Issue.6841
, pp. 1058-1064
-
-
Ochsenbein, A.F.1
Sierro, S.2
Odermatt, B.3
-
129
-
-
0012201556
-
A case report: Immune responses and clinical course of the first human use of granulocyte/macrophage-colony stimulating-factor-transduced autologous melanoma cells for immunotherapy
-
Ellem KA, O'Rourke MG, Johnson GR, et al. A case report: immune responses and clinical course of the first human use of granulocyte/macrophage-colony stimulating-factor-transduced autologous melanoma cells for immunotherapy. Cancer Immunol Immunother 1997; 44: 10-20
-
(1997)
Cancer Immunol Immunother
, vol.44
, pp. 10-20
-
-
Ellem, K.A.1
O'Rourke, M.G.2
Johnson, G.R.3
-
130
-
-
0030998998
-
Melanoma-reactive human cytotoxic T lymphocytes derived from skin biopsies of delayed-type hypersensitivity reactions induced by injection of an autologous melanoma cell line
-
Waanders GA, Rimoldi D, Lienard D, et al. Melanoma-reactive human cytotoxic T lymphocytes derived from skin biopsies of delayed-type hypersensitivity reactions induced by injection of an autologous melanoma cell line. Clin Cancer Res 1997; 3: 685-96
-
(1997)
Clin Cancer Res
, vol.3
, pp. 685-696
-
-
Waanders, G.A.1
Rimoldi, D.2
Lienard, D.3
-
132
-
-
0034618869
-
The HLA system: First of two parts
-
Klein J, Sato A. The HLA system: first of two parts. N Engl J Med 2000; 343: 702-9
-
(2000)
N Engl J Med
, vol.343
, pp. 702-709
-
-
Klein, J.1
Sato, A.2
-
133
-
-
0033991158
-
Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
-
Marincola FM, Jaffee EM, Hicklin DJ, et al. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv Immunol 2000; 74: 181-273
-
(2000)
Adv Immunol
, vol.74
, pp. 181-273
-
-
Marincola, F.M.1
Jaffee, E.M.2
Hicklin, D.J.3
-
134
-
-
0035889605
-
Primary melanoma tumour regression associated with an immune response to the tumour-associated antigen melan-A/MART-1
-
Saleh FH, Crotty KA, Hersey P, et al. Primary melanoma tumour regression associated with an immune response to the tumour-associated antigen melan-A/MART-1. Int J Cancer 2001; 94: 551-7
-
(2001)
Int J Cancer
, vol.94
, pp. 551-557
-
-
Saleh, F.H.1
Crotty, K.A.2
Hersey, P.3
-
136
-
-
0036096282
-
Frequency of MART-1/MelanA and gp100/PMel17-specific T cells in tumor metastases and cultured tumor-infiltrating lymphocytes
-
Seiter S, Monsurro V, Nielsen MB, et al. Frequency of MART-1/MelanA and gp100/PMel17-specific T cells in tumor metastases and cultured tumor-infiltrating lymphocytes. J Immunother 2002; 25: 252-63
-
(2002)
J Immunother
, vol.25
, pp. 252-263
-
-
Seiter, S.1
Monsurro, V.2
Nielsen, M.B.3
-
137
-
-
0033393224
-
The role of cytotoxic T-lymphocytes in the prevention and immune surveillance of tumors: Lessons from normal and immunodeficient mice
-
Svane IM, Boesen M, Engel AM. The role of cytotoxic T-lymphocytes in the prevention and immune surveillance of tumors: lessons from normal and immunodeficient mice. Med Oncol 1999; 16: 223-38
-
(1999)
Med Oncol
, vol.16
, pp. 223-238
-
-
Svane, I.M.1
Boesen, M.2
Engel, A.M.3
-
138
-
-
33646111713
-
Immunological characteristics correlating with clinical response to immunotherapy in patients with advanced metastatic melanoma
-
Jun;
-
Marshall JA, Forster TH, Purdie DM, et al. Immunological characteristics correlating with clinical response to immunotherapy in patients with advanced metastatic melanoma. Immunol Cell Biol 2006 Jun; 84 (3): 295-302
-
(2006)
Immunol Cell Biol
, vol.84
, Issue.3
, pp. 295-302
-
-
Marshall, J.A.1
Forster, T.H.2
Purdie, D.M.3
-
139
-
-
11844302141
-
Reciprocal changes in tumor antigenicity and antigen-specific T cell function during tumor progression
-
Dec 20;
-
Zhou G, Lu Z, McCadden JD, et al. Reciprocal changes in tumor antigenicity and antigen-specific T cell function during tumor progression. J Exp Med 2004 Dec 20; 200 (12): 1581-92
-
(2004)
J Exp Med
, vol.200
, Issue.12
, pp. 1581-1592
-
-
Zhou, G.1
Lu, Z.2
McCadden, J.D.3
-
140
-
-
0033056073
-
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
-
Jun;
-
Lee PP, Yee C, Savage PA, et al. Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nat Med 1999 Jun; 5 (6): 677-85
-
(1999)
Nat Med
, vol.5
, Issue.6
, pp. 677-685
-
-
Lee, P.P.1
Yee, C.2
Savage, P.A.3
-
141
-
-
30044437872
-
Breaking down the barriers to cancer immunotherapy
-
Dec;
-
Pure E, Allison JP, Schreiber RD. Breaking down the barriers to cancer immunotherapy. Nat Immunol 2005 Dec; 6 (12): 1207-10
-
(2005)
Nat Immunol
, vol.6
, Issue.12
, pp. 1207-1210
-
-
Pure, E.1
Allison, J.P.2
Schreiber, R.D.3
-
142
-
-
33646271857
-
Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment
-
Apr 1;, s
-
Gajewski TF. Identifying and overcoming immune resistance mechanisms in the melanoma tumor microenvironment. Clin Cancer Res 2006 Apr 1; 12 (7 Pt 2): 2326s-30s
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 PART 2
-
-
Gajewski, T.F.1
-
143
-
-
24344436369
-
Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance
-
Sep 1;
-
Willimsky G, Blankenstein T. Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance. Nature 2005 Sep 1; 437 (7055): 141-6
-
(2005)
Nature
, vol.437
, Issue.7055
, pp. 141-146
-
-
Willimsky, G.1
Blankenstein, T.2
-
144
-
-
27144500671
-
Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanoma
-
Nov 1;
-
Rosenberg SA, Sherry RM, Morton KE, et al. Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanoma. J Immunol 2005 Nov 1; 175 (9): 6169-76
-
(2005)
J Immunol
, vol.175
, Issue.9
, pp. 6169-6176
-
-
Rosenberg, S.A.1
Sherry, R.M.2
Morton, K.E.3
-
145
-
-
17844402285
-
TGF-beta 1 attenuates the acquisition and expression of effector function by tumor antigen-specific human memory CD8 T cells
-
May 1;
-
Ahmadzadeh M, Rosenberg SA. TGF-beta 1 attenuates the acquisition and expression of effector function by tumor antigen-specific human memory CD8 T cells. J Immunol 2005 May 1; 174 (9): 5215-23
-
(2005)
J Immunol
, vol.174
, Issue.9
, pp. 5215-5223
-
-
Ahmadzadeh, M.1
Rosenberg, S.A.2
-
146
-
-
19944434269
-
High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens
-
Jan 17;
-
Germeau C, Ma W, Schiavetti F, et al. High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens. J Exp Med 2005 Jan 17; 201 (2): 241-8
-
(2005)
J Exp Med
, vol.201
, Issue.2
, pp. 241-248
-
-
Germeau, C.1
Ma, W.2
Schiavetti, F.3
-
147
-
-
33746214819
-
New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site
-
Aug 1;
-
Appay V, Jandus C, Voelter V, et al. New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site. J Immunol 2006 Aug 1; 177 (3): 1670-8
-
(2006)
J Immunol
, vol.177
, Issue.3
, pp. 1670-1678
-
-
Appay, V.1
Jandus, C.2
Voelter, V.3
-
148
-
-
23244443617
-
-
King IL, Segal BM. Cutting edge: IL-12 induces CD4+CD25- T cell activation in the presence of T regulatory cells. J Immunol 2005 Jul 15; 175 (2): 641-5
-
King IL, Segal BM. Cutting edge: IL-12 induces CD4+CD25- T cell activation in the presence of T regulatory cells. J Immunol 2005 Jul 15; 175 (2): 641-5
-
-
-
-
149
-
-
13844262749
-
Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: Clinical efficacy
-
Jan;
-
Heinzerling L, Burg G, Dummer R, et al. Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: clinical efficacy. Hum Gene Ther 2005 Jan; 16 (1): 35-48
-
(2005)
Hum Gene Ther
, vol.16
, Issue.1
, pp. 35-48
-
-
Heinzerling, L.1
Burg, G.2
Dummer, R.3
-
150
-
-
33744908300
-
-
Wang RF. Regulatory T cells and toll-like receptors in cancer therapy. Cancer Res 2006 May 15; 66 (10): 4987-90
-
Wang RF. Regulatory T cells and toll-like receptors in cancer therapy. Cancer Res 2006 May 15; 66 (10): 4987-90
-
-
-
-
151
-
-
11144355748
-
Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers
-
Mar 8;
-
Bartlett JB, Michael A, Clarke IA, et al. Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers. Br J Cancer 2004 Mar 8; 90 (5): 955-61
-
(2004)
Br J Cancer
, vol.90
, Issue.5
, pp. 955-961
-
-
Bartlett, J.B.1
Michael, A.2
Clarke, I.A.3
-
152
-
-
10744231369
-
Immunomodulatory drug costimulates T cells via the B7-CD28 pathway
-
Mar 1;
-
LeBlanc R, Hideshima T, Catley LP, et al. Immunomodulatory drug costimulates T cells via the B7-CD28 pathway. Blood 2004 Mar 1; 103 (5): 1787-90
-
(2004)
Blood
, vol.103
, Issue.5
, pp. 1787-1790
-
-
LeBlanc, R.1
Hideshima, T.2
Catley, L.P.3
-
153
-
-
0036381106
-
Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells
-
Oct;
-
Marriott JB, Clarke IA, Dredge K, et al. Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells. Clin Exp Immunol 2002 Oct; 130 (1): 75-84
-
(2002)
Clin Exp Immunol
, vol.130
, Issue.1
, pp. 75-84
-
-
Marriott, J.B.1
Clarke, I.A.2
Dredge, K.3
-
154
-
-
33745166322
-
Skin hypoxia: A promoting environmental factor in melanomagenesis
-
Jun;
-
Bedogni B, Powell MB. Skin hypoxia: a promoting environmental factor in melanomagenesis. Cell Cycle 2006 Jun; 5 (12): 1258-61
-
(2006)
Cell Cycle
, vol.5
, Issue.12
, pp. 1258-1261
-
-
Bedogni, B.1
Powell, M.B.2
-
155
-
-
33646801986
-
Hypoxic microenvironment as a cradle for melanoma development and progression
-
May;
-
Michaylira CZ, Nakagawa H. Hypoxic microenvironment as a cradle for melanoma development and progression. Cancer Biol Ther 2006 May; 5 (5): 476-9
-
(2006)
Cancer Biol Ther
, vol.5
, Issue.5
, pp. 476-479
-
-
Michaylira, C.Z.1
Nakagawa, H.2
-
156
-
-
33846945010
-
Hypoxic repression of STAT1 and its downstream genes by a pVHL/HIF-1 target DEC1/STRA13
-
Feb 8;
-
Ivanov SV, Salnikow K, Ivanova AV, et al. Hypoxic repression of STAT1 and its downstream genes by a pVHL/HIF-1 target DEC1/STRA13. Oncogene 2007 Feb 8; 26 (6): 802-12
-
(2007)
Oncogene
, vol.26
, Issue.6
, pp. 802-812
-
-
Ivanov, S.V.1
Salnikow, K.2
Ivanova, A.V.3
-
157
-
-
0344873719
-
Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells
-
Oct 31;
-
Joung YH, Park JH, Park T, et al. Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells. Exp Mol Med 2003 Oct 31; 35 (5): 350-7
-
(2003)
Exp Mol Med
, vol.35
, Issue.5
, pp. 350-357
-
-
Joung, Y.H.1
Park, J.H.2
Park, T.3
-
158
-
-
33646527342
-
Phosphorylation and activation of STAT proteins by hypoxia in breast cancer cells
-
Apr;
-
Lee MY, Joung YH, Lim EJ, et al. Phosphorylation and activation of STAT proteins by hypoxia in breast cancer cells. Breast 2006 Apr; 15 (2): 187-95
-
(2006)
Breast
, vol.15
, Issue.2
, pp. 187-195
-
-
Lee, M.Y.1
Joung, Y.H.2
Lim, E.J.3
-
159
-
-
0036305649
-
Malignant melanoma associates with Th1/Th2 imbalance that coincides with disease progression and immunotherapy response
-
Lauerova L, Dusek L, Simickova M, et al. Malignant melanoma associates with Th1/Th2 imbalance that coincides with disease progression and immunotherapy response. Neoplasma 2002; 49 (3): 159-66
-
(2002)
Neoplasma
, vol.49
, Issue.3
, pp. 159-166
-
-
Lauerova, L.1
Dusek, L.2
Simickova, M.3
-
160
-
-
0742287072
-
Antigen-based immunotherapy of melanoma: Canvaxin therapeutic polyvalent cancer vaccine
-
Dec;
-
Hsueh EC, Morton DL. Antigen-based immunotherapy of melanoma: Canvaxin therapeutic polyvalent cancer vaccine. Semin Cancer Biol 2003 Dec; 13 (6): 401-7
-
(2003)
Semin Cancer Biol
, vol.13
, Issue.6
, pp. 401-407
-
-
Hsueh, E.C.1
Morton, D.L.2
-
161
-
-
33646887560
-
Tumour-associated macrophages and melanoma tumourigenesis: Integrating the complexity
-
Jun;
-
Hussein MR. Tumour-associated macrophages and melanoma tumourigenesis: integrating the complexity. Int J Exp Pathol 2006 Jun; 87 (3): 163-76
-
(2006)
Int J Exp Pathol
, vol.87
, Issue.3
, pp. 163-176
-
-
Hussein, M.R.1
-
162
-
-
0035336409
-
Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells
-
Jun 1;
-
Nesbit M, Schaider H, Miller TH, et al. Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells. J Immunol 2001 Jun 1; 166 (11): 6483-90
-
(2001)
J Immunol
, vol.166
, Issue.11
, pp. 6483-6490
-
-
Nesbit, M.1
Schaider, H.2
Miller, T.H.3
-
163
-
-
34248139403
-
Macrophage migration inhibitory factor protein and mRNA expression in cutaneous melanocytic tumours
-
Feb;
-
Miracco C, De Nisi MC, Arcuri F, et al. Macrophage migration inhibitory factor protein and mRNA expression in cutaneous melanocytic tumours. Int J Oncol 2006 Feb; 28 (2): 345-52
-
(2006)
Int J Oncol
, vol.28
, Issue.2
, pp. 345-352
-
-
Miracco, C.1
De Nisi, M.C.2
Arcuri, F.3
-
164
-
-
27644590410
-
Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: Role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A
-
Oct;
-
Varney ML, Johansson SL, Singh RK. Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A. Melanoma Res 2005 Oct; 15 (5): 417-25
-
(2005)
Melanoma Res
, vol.15
, Issue.5
, pp. 417-425
-
-
Varney, M.L.1
Johansson, S.L.2
Singh, R.K.3
-
165
-
-
33644854945
-
MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkappaB ligand for bone resorption
-
Jan 13;
-
Kim MS, Day CJ, Selinger CI, et al. MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkappaB ligand for bone resorption. J Biol Chem 2006 Jan 13; 281 (2): 1274-85
-
(2006)
J Biol Chem
, vol.281
, Issue.2
, pp. 1274-1285
-
-
Kim, M.S.1
Day, C.J.2
Selinger, C.I.3
-
166
-
-
33751214818
-
NFAT transcription factors in control of peripheral T cell tolerance
-
Nov;
-
Serfling E, Klein-Hessling S, Palmetshofer A, et al. NFAT transcription factors in control of peripheral T cell tolerance. Eur J Immunol 2006 Nov; 36 (11): 2837-43
-
(2006)
Eur J Immunol
, vol.36
, Issue.11
, pp. 2837-2843
-
-
Serfling, E.1
Klein-Hessling, S.2
Palmetshofer, A.3
-
167
-
-
17044393922
-
Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
-
Apr 5;
-
Bettelli E, Dastrange M, Oukka M. Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A 2005 Apr 5; 102 (14): 5138-43
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.14
, pp. 5138-5143
-
-
Bettelli, E.1
Dastrange, M.2
Oukka, M.3
-
168
-
-
33746189406
-
FOXP3 and NFAT: Partners in tolerance
-
Jul 28;
-
Rudensky AY, Gavin M, Zheng Y. FOXP3 and NFAT: partners in tolerance. Cell 2006 Jul 28; 126 (2): 253-6
-
(2006)
Cell
, vol.126
, Issue.2
, pp. 253-256
-
-
Rudensky, A.Y.1
Gavin, M.2
Zheng, Y.3
-
169
-
-
33746228122
-
FOXP3 controls regulatory T cell function through cooperation with NFAT
-
Jul 28;
-
Wu Y, Borde M, Heissmeyer V, et al. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 2006 Jul 28; 126 (2): 375-87
-
(2006)
Cell
, vol.126
, Issue.2
, pp. 375-387
-
-
Wu, Y.1
Borde, M.2
Heissmeyer, V.3
-
170
-
-
29444438572
-
Paracrine regulation of vascular endothelial growth factor-a expression during macrophage-melanoma cell interaction: Role of monocyte chemotactic protein-1 and macrophage colony-stimulating factor
-
Nov;
-
Varney ML, Olsen KJ, Mosley RL, et al. Paracrine regulation of vascular endothelial growth factor-a expression during macrophage-melanoma cell interaction: role of monocyte chemotactic protein-1 and macrophage colony-stimulating factor. J Interferon Cytokine Res 2005 Nov; 25 (11): 674-83
-
(2005)
J Interferon Cytokine Res
, vol.25
, Issue.11
, pp. 674-683
-
-
Varney, M.L.1
Olsen, K.J.2
Mosley, R.L.3
-
171
-
-
31544446571
-
Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
-
Jan 15;
-
Huang B, Pan PY, Li Q, et al. Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res 2006 Jan 15; 66 (2): 1123-31
-
(2006)
Cancer Res
, vol.66
, Issue.2
, pp. 1123-1131
-
-
Huang, B.1
Pan, P.Y.2
Li, Q.3
-
172
-
-
25844503817
-
Tumor immunity: A balancing act between T cell activation, macrophage activation and tumor-induced immune suppression
-
Nov;
-
Sinha P, Clements VK, Miller S, et al. Tumor immunity: a balancing act between T cell activation, macrophage activation and tumor-induced immune suppression. Cancer Immunol Immunother 2005 Nov; 54 (11): 1137-42
-
(2005)
Cancer Immunol Immunother
, vol.54
, Issue.11
, pp. 1137-1142
-
-
Sinha, P.1
Clements, V.K.2
Miller, S.3
-
173
-
-
4444279152
-
Regulatory T-cell response and tumor vaccine-induced cytotoxic T lymphocytes in human melanoma
-
Aug;
-
Chakraborty NG, Chattopadhyay S, Mehrotra S, et al. Regulatory T-cell response and tumor vaccine-induced cytotoxic T lymphocytes in human melanoma. Hum Immunol 2004 Aug; 65 (8): 794-802
-
(2004)
Hum Immunol
, vol.65
, Issue.8
, pp. 794-802
-
-
Chakraborty, N.G.1
Chattopadhyay, S.2
Mehrotra, S.3
-
174
-
-
10844269645
-
Dendritic cells loaded with stressed tumor cells elicit long-lasting protective tumor immunity in mice depleted of CD4+CD25+ regulatory T cells
-
Jan 1;
-
Prasad SJ, Farrand KJ, Matthews SA, et al. Dendritic cells loaded with stressed tumor cells elicit long-lasting protective tumor immunity in mice depleted of CD4+CD25+ regulatory T cells. J Immunol 2005 Jan 1; 174 (1): 90-8
-
(2005)
J Immunol
, vol.174
, Issue.1
, pp. 90-98
-
-
Prasad, S.J.1
Farrand, K.J.2
Matthews, S.A.3
-
175
-
-
28544452409
-
Combination B7-Fc fusion protein treatment and Treg cell depletion therapy
-
Dec 1;
-
Liu A, Hu P, Khawli LA, et al. Combination B7-Fc fusion protein treatment and Treg cell depletion therapy. Clin Cancer Res 2005 Dec 1; 11 (23): 8492-502
-
(2005)
Clin Cancer Res
, vol.11
, Issue.23
, pp. 8492-8502
-
-
Liu, A.1
Hu, P.2
Khawli, L.A.3
-
176
-
-
30144444279
-
Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
-
Dec;
-
Dannull J, Su Z, Rizzieri D, et al. Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest 2005 Dec; 115 (12): 3623-33
-
(2005)
J Clin Invest
, vol.115
, Issue.12
, pp. 3623-3633
-
-
Dannull, J.1
Su, Z.2
Rizzieri, D.3
-
177
-
-
31344474166
-
Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression
-
Feb;
-
Serafini P, Borrello I, Bronte V. Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression. Semin Cancer Biol 2006 Feb; 16 (1): 53-65
-
(2006)
Semin Cancer Biol
, vol.16
, Issue.1
, pp. 53-65
-
-
Serafini, P.1
Borrello, I.2
Bronte, V.3
-
178
-
-
20144368873
-
Gene expression profiling reveals cross-talk between melanoma and fibroblasts: Implications for host-tumor interactions in metastasis
-
May 15;
-
Gallagher PG, Bao Y, Prorock A, et al. Gene expression profiling reveals cross-talk between melanoma and fibroblasts: implications for host-tumor interactions in metastasis. Cancer Res 2005 May 15; 65 (10): 4134-46
-
(2005)
Cancer Res
, vol.65
, Issue.10
, pp. 4134-4146
-
-
Gallagher, P.G.1
Bao, Y.2
Prorock, A.3
-
179
-
-
1542373593
-
Expression of galectins in cancer: A critical review
-
van den Brule F, Califice S, Castronovo V. Expression of galectins in cancer: a critical review. Glycoconj J 2004; 19 (7-9): 537-42
-
(2004)
Glycoconj J
, vol.19
, Issue.7-9
, pp. 537-542
-
-
van den Brule, F.1
Califice, S.2
Castronovo, V.3
-
180
-
-
30744445427
-
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death
-
Jan 15;
-
Stillman BN, Hsu DK, Pang M, et al. Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death. J Immunol 2006 Jan 15; 176 (2): 778-89
-
(2006)
J Immunol
, vol.176
, Issue.2
, pp. 778-789
-
-
Stillman, B.N.1
Hsu, D.K.2
Pang, M.3
-
181
-
-
33646091536
-
High serum galectin-3 in advanced melanoma: Preliminary results
-
Jan;
-
Vereecken P, Zouaoui Boudjeltia K, Debray C, et al. High serum galectin-3 in advanced melanoma: preliminary results. Clin Exp Dermatol 2006 Jan; 31 (1): 105-9
-
(2006)
Clin Exp Dermatol
, vol.31
, Issue.1
, pp. 105-109
-
-
Vereecken, P.1
Zouaoui Boudjeltia, K.2
Debray, C.3
-
182
-
-
33646509028
-
Galectin-3 expression correlates with apoptosis of tumor-associated lymphocytes in human melanoma biopsies
-
May;
-
Zubieta MR, Furman D, Barrio M, et al. Galectin-3 expression correlates with apoptosis of tumor-associated lymphocytes in human melanoma biopsies. Am J Pathol 2006 May; 168 (5): 1666-75
-
(2006)
Am J Pathol
, vol.168
, Issue.5
, pp. 1666-1675
-
-
Zubieta, M.R.1
Furman, D.2
Barrio, M.3
-
183
-
-
33749556658
-
Galectin-1: A small protein with major functions
-
Nov;
-
Camby I, Mercier ML, Lefranc F, et al. Galectin-1: a small protein with major functions. Glycobiology 2006 Nov; 16 (11): 137R-57R
-
(2006)
Glycobiology
, vol.16
, Issue.11
-
-
Camby, I.1
Mercier, M.L.2
Lefranc, F.3
-
184
-
-
33646491737
-
Galectin-1 suppresses autoimmune retinal disease by promoting concomitant Th2- and T regulatory-mediated anti-inflammatory responses
-
May 15;
-
Toscano MA, Commodaro AG, Ilarregui JM, et al. Galectin-1 suppresses autoimmune retinal disease by promoting concomitant Th2- and T regulatory-mediated anti-inflammatory responses. J Immunol 2006 May 15; 176 (10): 6323-32
-
(2006)
J Immunol
, vol.176
, Issue.10
, pp. 6323-6332
-
-
Toscano, M.A.1
Commodaro, A.G.2
Ilarregui, J.M.3
-
185
-
-
9744222923
-
Dimeric galectin-1 induces IL-10 production in T-lymphocytes: An important tool in the regulation of the immune response
-
Dec;
-
van der Leij J, van den Berg A, Blokzijl T, et al. Dimeric galectin-1 induces IL-10 production in T-lymphocytes: an important tool in the regulation of the immune response. J Pathol 2004 Dec; 204 (5): 511-8
-
(2004)
J Pathol
, vol.204
, Issue.5
, pp. 511-518
-
-
van der Leij, J.1
van den Berg, A.2
Blokzijl, T.3
-
186
-
-
33747856478
-
Strongly enhanced IL-10 production using stable galectin-1 homodimers
-
Jan;
-
van der Leij J, van den Berg A, Harms G, et al. Strongly enhanced IL-10 production using stable galectin-1 homodimers. Mol Immunol 2007 Jan; 44 (4): 506-13
-
(2007)
Mol Immunol
, vol.44
, Issue.4
, pp. 506-513
-
-
van der Leij, J.1
van den Berg, A.2
Harms, G.3
-
187
-
-
12144285871
-
Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; a potential mechanism of tumor-immune privilege
-
Mar;
-
Rubinstein N, Alvarez M, Zwirner NW, et al. Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; a potential mechanism of tumor-immune privilege. Cancer Cell 2004 Mar; 5 (3): 241-51
-
(2004)
Cancer Cell
, vol.5
, Issue.3
, pp. 241-251
-
-
Rubinstein, N.1
Alvarez, M.2
Zwirner, N.W.3
-
188
-
-
33748428203
-
T-cell costimulation: Biology, therapeutic potential, and challenges
-
Sep 7;
-
Sharpe AH, Abbas AK. T-cell costimulation: biology, therapeutic potential, and challenges. N Engl J Med 2006 Sep 7; 355 (10): 973-5
-
(2006)
N Engl J Med
, vol.355
, Issue.10
, pp. 973-975
-
-
Sharpe, A.H.1
Abbas, A.K.2
-
189
-
-
28244492012
-
Analysis of the cellular mechanism of antitu mor responses and autoimmunity in patients treated with CTLA-4 blockade
-
Dec 1;
-
Maker AV, Attia P, Rosenberg SA. Analysis of the cellular mechanism of antitu mor responses and autoimmunity in patients treated with CTLA-4 blockade. J Immunol 2005 Dec 1; 175 (11): 7746-54
-
(2005)
J Immunol
, vol.175
, Issue.11
, pp. 7746-7754
-
-
Maker, A.V.1
Attia, P.2
Rosenberg, S.A.3
-
190
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
Jul 8;
-
Phan GQ, Yang JC, Sherry RM, et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci U S A 2003 Jul 8; 100 (14): 8372-7
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.14
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
-
191
-
-
24944459890
-
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
-
Sep 1;
-
Attia P, Phan GQ, Maker AV, et al. Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol 2005 Sep 1; 23 (25): 6043-53
-
(2005)
J Clin Oncol
, vol.23
, Issue.25
, pp. 6043-6053
-
-
Attia, P.1
Phan, G.Q.2
Maker, A.V.3
-
192
-
-
27844458057
-
Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: A phase I/II study
-
Dec;
-
Maker AV, Phan GQ, Attia P, et al. Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a phase I/II study. Ann Surg Oncol. 2005 Dec; 12 (12): 1005-16
-
(2005)
Ann Surg Oncol
, vol.12
, Issue.12
, pp. 1005-1016
-
-
Maker, A.V.1
Phan, G.Q.2
Attia, P.3
-
193
-
-
33747878218
-
Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma
-
Jul-Aug;
-
Maker AV, Yang JC, Sherry RM, et al. Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma. J Immunother 2006 Jul-Aug; 29 (4): 455-63
-
(2006)
J Immunother
, vol.29
, Issue.4
, pp. 455-463
-
-
Maker, A.V.1
Yang, J.C.2
Sherry, R.M.3
-
194
-
-
34347251973
-
-
Gomez-Navarro J, Sharma A, Bozon V, et al. Dose and schedule selection for the anti-CTLA4 monoclonal antibody ticilimumab in patients (pts) with metastatic melanoma: proceedings of ASCO annual meeting: part I [abstract]. J Clin Oncol 2006 Jun 20; 24 (18 Suppl.): 8032
-
Gomez-Navarro J, Sharma A, Bozon V, et al. Dose and schedule selection for the anti-CTLA4 monoclonal antibody ticilimumab in patients (pts) with metastatic melanoma: proceedings of ASCO annual meeting: part I [abstract]. J Clin Oncol 2006 Jun 20; 24 (18 Suppl.): 8032
-
-
-
-
195
-
-
33646886997
-
Biologic and immunomodulatory events after CTLA-4 blockade with ticilimumab in patients with advanced malignant melanoma
-
Jun 1;
-
Reuben JM, Lee BN, Li C, et al. Biologic and immunomodulatory events after CTLA-4 blockade with ticilimumab in patients with advanced malignant melanoma. Cancer 2006 Jun 1; 106 (11): 2437-44
-
(2006)
Cancer
, vol.106
, Issue.11
, pp. 2437-2444
-
-
Reuben, J.M.1
Lee, B.N.2
Li, C.3
-
196
-
-
32644467549
-
Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
-
Dec 10;
-
Ribas A, Camacho LH, Lopez-Berestein G, et al. Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. J Clin Oncol 2005 Dec 10; 23 (35): 8968-77
-
(2005)
J Clin Oncol
, vol.23
, Issue.35
, pp. 8968-8977
-
-
Ribas, A.1
Camacho, L.H.2
Lopez-Berestein, G.3
-
197
-
-
34347207272
-
-
Gerritsen W, Van Den Eertwegh AJ, De Gruijl T, et al. A dose-escalation trial of GM-CSF-gene transduced allogeneic prostate cancer cellular immunotherapy in combination with a fully human anti-CTLA antibody (MDX-010, ipilimumab) in patients with metastatic hormone-refractory prostate cancer (mHRPC): proceedings of ASCO annual meeting: part I [abstract]. J Clin Oncol 2006 Jun 20; 24 (18 Suppl.): 2500
-
Gerritsen W, Van Den Eertwegh AJ, De Gruijl T, et al. A dose-escalation trial of GM-CSF-gene transduced allogeneic prostate cancer cellular immunotherapy in combination with a fully human anti-CTLA antibody (MDX-010, ipilimumab) in patients with metastatic hormone-refractory prostate cancer (mHRPC): proceedings of ASCO annual meeting: part I [abstract]. J Clin Oncol 2006 Jun 20; 24 (18 Suppl.): 2500
-
-
-
-
198
-
-
33646252963
-
Cytokine-based therapy and biochemotherapy for advanced melanoma
-
Apr 1;, s
-
Atkins MB. Cytokine-based therapy and biochemotherapy for advanced melanoma. Clin Cancer Res 2006 Apr 1; 12 (7 Pt 2): 2353s-8s
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 PART 2
-
-
Atkins, M.B.1
-
199
-
-
33746092947
-
Immune suppression in the tumor microenviron ment
-
May-Jun;
-
Gajewski TF, Meng Y, Harlin H. Immune suppression in the tumor microenviron ment. J Immunother 2006 May-Jun; 29 (3): 233-40
-
(2006)
J Immunother
, vol.29
, Issue.3
, pp. 233-240
-
-
Gajewski, T.F.1
Meng, Y.2
Harlin, H.3
-
200
-
-
33646268668
-
Immunosuppression in melanoma immunotherapy: Potential opportunities for intervention
-
Apr 1;, s
-
Lizee G, Radvanyi LG, Overwijk WW, et al. Immunosuppression in melanoma immunotherapy: potential opportunities for intervention. Clin Cancer Res 2006 Apr 1; 12 (7 Pt 2): 2359s-65s
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 PART 2
-
-
Lizee, G.1
Radvanyi, L.G.2
Overwijk, W.W.3
-
201
-
-
33748343409
-
Improving antitumor immune responses by circumventing immunoregulatory cells and mechanisms
-
Aug 15;
-
Lizee G, Radvanyi LG, Overwijk WW, et al. Improving antitumor immune responses by circumventing immunoregulatory cells and mechanisms. Clin Cancer Res 2006 Aug 15; 12 (16): 4794-803
-
(2006)
Clin Cancer Res
, vol.12
, Issue.16
, pp. 4794-4803
-
-
Lizee, G.1
Radvanyi, L.G.2
Overwijk, W.W.3
-
202
-
-
0037386931
-
Changes in the presence of multiple markers of circulating melanoma cells correlate with clinical outcome in patients with melanoma
-
Apr;
-
Reynolds SR, Albrecht J, Shapiro RL, et al. Changes in the presence of multiple markers of circulating melanoma cells correlate with clinical outcome in patients with melanoma. Clin Cancer Res 2003 Apr; 9 (4): 1497-502
-
(2003)
Clin Cancer Res
, vol.9
, Issue.4
, pp. 1497-1502
-
-
Reynolds, S.R.1
Albrecht, J.2
Shapiro, R.L.3
-
203
-
-
14844309609
-
Immunotherapy with autologous tumor cell-BCG vaccine in patients with colon cancer: A prospective study of medical and economic benefits
-
Mar 18;
-
Uyl-de Groot CA, Vermorken JB, Hanna Jr MG, et al. Immunotherapy with autologous tumor cell-BCG vaccine in patients with colon cancer: a prospective study of medical and economic benefits. Vaccine 2005 Mar 18; 23 (17-18): 2379-87
-
(2005)
Vaccine
, vol.23
, Issue.17-18
, pp. 2379-2387
-
-
Uyl-de Groot, C.A.1
Vermorken, J.B.2
Hanna Jr, M.G.3
-
204
-
-
0033985949
-
Adjuvant active specific immunotherapy for stage II and III colon cancer with an autologous tumor cell vaccine: Eastern Cooperative Oncology Group Study E5283
-
Jan;
-
Harris JE, Ryan L, Hoover Jr HC, et al. Adjuvant active specific immunotherapy for stage II and III colon cancer with an autologous tumor cell vaccine: Eastern Cooperative Oncology Group Study E5283. J Clin Oncol 2000 Jan; 18 (1): 148-57
-
(2000)
J Clin Oncol
, vol.18
, Issue.1
, pp. 148-157
-
-
Harris, J.E.1
Ryan, L.2
Hoover Jr, H.C.3
-
205
-
-
10744230275
-
Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: Phase III, randomised controlled trial
-
Feb 21;
-
Jocham D, Richter A, Hoffmann L, et al. Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: phase III, randomised controlled trial. Lancet 2004 Feb 21; 363 (9409): 594-9
-
(2004)
Lancet
, vol.363
, Issue.9409
, pp. 594-599
-
-
Jocham, D.1
Richter, A.2
Hoffmann, L.3
-
206
-
-
0036682045
-
Enhanced humoral immune response correlates with improved disease-free and overall survival in American Joint Committee on Cancer stage II melanoma patients receiving adjuvant polyvalent vaccine
-
Aug 1;
-
DiFronzo LA, Gupta RK, Essner R, et al. Enhanced humoral immune response correlates with improved disease-free and overall survival in American Joint Committee on Cancer stage II melanoma patients receiving adjuvant polyvalent vaccine. J Clin Oncol 2002 Aug 1; 20 (15): 3242-8
-
(2002)
J Clin Oncol
, vol.20
, Issue.15
, pp. 3242-3248
-
-
DiFronzo, L.A.1
Gupta, R.K.2
Essner, R.3
|