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Volumn 106, Issue 48, 2009, Pages 20417-20422

Design and construction of diverse mammalian prion strains

Author keywords

Amyloid; Conformation; Neurodegeneration; Stability; Synthetic prions

Indexed keywords

AMYLOID; PRION PROTEIN;

EID: 73949160065     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0910350106     Document Type: Article
Times cited : (188)

References (54)
  • 1
    • 0023205075 scopus 로고
    • Biological evidence that the scrapie agent has an independent genome
    • Bruce ME, Dickinson AG (1987) Biological evidence that the scrapie agent has an independent genome. J Gen Virol 68:79-89.
    • (1987) J Gen Virol , vol.68 , pp. 79-89
    • Bruce, M.E.1    Dickinson, A.G.2
  • 2
    • 0025681138 scopus 로고
    • Spontaneous neurodegeneration in transgenic mice with mutant prion protein
    • Hsiao KK, et al. (1990) Spontaneous neurodegeneration in transgenic mice with mutant prion protein. Science 250:1587-1590.
    • (1990) Science , vol.250 , pp. 1587-1590
    • Hsiao, K.K.1
  • 3
    • 0028608963 scopus 로고
    • Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein
    • Hsiao KK, et al. (1994) Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proc Natl Acad Sci USA 91:9126-9130.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9126-9130
    • Hsiao, K.K.1
  • 4
    • 0842304471 scopus 로고    scopus 로고
    • Sc conformers induced by a synthetic peptide and several prion strains
    • Sc conformers induced by a synthetic peptide and several prion strains. J Virol 78:2088-2099.
    • (2004) J Virol , vol.78 , pp. 2088-2099
    • Tremblay, P.1
  • 5
    • 22744448690 scopus 로고    scopus 로고
    • Immunodetection of disease-associated mutant PrP, which accelerates disease in GSS transgenic mice
    • Nazor KE, et al. (2005) Immunodetection of disease-associated mutant PrP, which accelerates disease in GSS transgenic mice. EMBO J 24:2472-2480.
    • (2005) EMBO J , vol.24 , pp. 2472-2480
    • Nazor, K.E.1
  • 6
    • 0034723133 scopus 로고    scopus 로고
    • A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice
    • Kaneko K, et al. (2000) A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice. J Mol Biol 295:997-1007.
    • (2000) J Mol Biol , vol.295 , pp. 997-1007
    • Kaneko, K.1
  • 7
    • 0034725747 scopus 로고    scopus 로고
    • +] factor by in vitro-converted Sup35 protein. Science 289:595-599.
    • +] factor by in vitro-converted Sup35 protein. Science 289:595-599.
  • 9
    • 27144451227 scopus 로고    scopus 로고
    • Prion generation in vitro: Amyloid of Ure2p is infectious
    • Brachmann A, Baxa U, Wickner RB (2005) Prion generation in vitro: Amyloid of Ure2p is infectious. EMBO J 24:3082-3092.
    • (2005) EMBO J , vol.24 , pp. 3082-3092
    • Brachmann, A.1    Baxa, U.2    Wickner, R.B.3
  • 10
    • 1642633056 scopus 로고    scopus 로고
    • Conformational variations in an infectious protein determine prion strain differences
    • Tanaka M, Chien P, Naber N, Cooke R, Weissman JS (2004) Conformational variations in an infectious protein determine prion strain differences. Nature 428:323-328.
    • (2004) Nature , vol.428 , pp. 323-328
    • Tanaka, M.1    Chien, P.2    Naber, N.3    Cooke, R.4    Weissman, J.S.5
  • 11
    • 1642617641 scopus 로고    scopus 로고
    • Protein-only transmission of three yeast prion strains
    • King CY, Diaz-Avalos R (2004) Protein-only transmission of three yeast prion strains. Nature 428:319-323.
    • (2004) Nature , vol.428 , pp. 319-323
    • King, C.Y.1    Diaz-Avalos, R.2
  • 12
    • 3442889359 scopus 로고    scopus 로고
    • Synthetic mammalian prions
    • Legname G, et al. (2004) Synthetic mammalian prions. Science 305:673-676.
    • (2004) Science , vol.305 , pp. 673-676
    • Legname, G.1
  • 13
    • 68949163542 scopus 로고    scopus 로고
    • Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice
    • Jackson WS, et al. (2009) Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice. Neuron 63:438-450.
    • (2009) Neuron , vol.63 , pp. 438-450
    • Jackson, W.S.1
  • 14
    • 0017643758 scopus 로고
    • Unconventional viruses and the origin and disappearance of kuru
    • Gajdusek DC (1977) Unconventional viruses and the origin and disappearance of kuru. Science 197:943-960.
    • (1977) Science , vol.197 , pp. 943-960
    • Gajdusek, D.C.1
  • 16
    • 33750310849 scopus 로고    scopus 로고
    • Prions and their partners in crime
    • Caughey B, Baron GS (2006) Prions and their partners in crime. Nature 443:803-810.
    • (2006) Nature , vol.443 , pp. 803-810
    • Caughey, B.1    Baron, G.S.2
  • 17
    • 36049020231 scopus 로고    scopus 로고
    • A general model of prion strains and their pathogenicity
    • Collinge J, Clarke AR (2007) A general model of prion strains and their pathogenicity. Science 318:930-936.
    • (2007) Science , vol.318 , pp. 930-936
    • Collinge, J.1    Clarke, A.R.2
  • 19
    • 0014500760 scopus 로고
    • A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7
    • MeikleVM
    • Dickinson AG, MeikleVM(1969) A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7. Genet Res 13:213-225.
    • (1969) Genet Res , vol.13 , pp. 213-225
    • Dickinson, A.G.1
  • 20
    • 0015550206 scopus 로고
    • Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation
    • Fraser H, Dickinson AG (1973) Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation. Journal of Comparative Pathology 83:29-40.
    • (1973) Journal of Comparative Pathology , vol.83 , pp. 29-40
    • Fraser, H.1    Dickinson, A.G.2
  • 21
    • 0028043661 scopus 로고
    • Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy
    • Bessen RA, Marsh RF (1994) Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy. J Virol 68:7859-7868.
    • (1994) J Virol , vol.68 , pp. 7859-7868
    • Bessen, R.A.1    Marsh, R.F.2
  • 22
    • 12644272790 scopus 로고    scopus 로고
    • Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity
    • Telling GC, et al. (1996) Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science 274:2079-2082.
    • (1996) Science , vol.274 , pp. 2079-2082
    • Telling, G.C.1
  • 23
    • 0029831213 scopus 로고    scopus 로고
    • Molecular analysis of prion strain variation and the aetiology of "new variant" CJD
    • Collinge J, Sidle KCL, Meads J, Ironside J, Hill AF (1996) Molecular analysis of prion strain variation and the aetiology of "new variant" CJD. Nature 383:685-690.
    • (1996) Nature , vol.383 , pp. 685-690
    • Collinge, J.1    Sidle, K.C.L.2    Meads, J.3    Ironside, J.4    Hill, A.F.5
  • 24
    • 13844321726 scopus 로고    scopus 로고
    • Strain-specified characteristics of mouse synthetic prions
    • Legname G, et al. (2005) Strain-specified characteristics of mouse synthetic prions. Proc Natl Acad Sci USA 102:2168-2173.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2168-2173
    • Legname, G.1
  • 25
    • 34447639732 scopus 로고    scopus 로고
    • Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes
    • Legname G, et al. (2006) Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes. Proc Natl Acad Sci USA 103:19105-19110.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 19105-19110
    • Legname, G.1
  • 26
    • 0013691975 scopus 로고
    • Screening for amyloid with the thioflavin-t fluorescent method
    • Rogers DR (1965) Screening for amyloid with the thioflavin-t fluorescent method.Am J Clin Pathol 44:59-61.
    • (1965) Am J Clin Pathol , vol.44 , pp. 59-61
    • Rogers, D.R.1
  • 27
    • 0028276015 scopus 로고
    • Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice
    • Carlson GA, et al. (1994) Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice. Proc Natl Acad Sci USA 91:5690-5694.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5690-5694
    • Carlson, G.A.1
  • 28
    • 0029740354 scopus 로고    scopus 로고
    • Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice
    • Telling GC, et al. (1996) Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice. Genes Dev 10:1736-1750.
    • (1996) Genes Dev , vol.10 , pp. 1736-1750
    • Telling, G.C.1
  • 29
    • 0028052363 scopus 로고
    • Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
    • Westaway D, et al. (1994) Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell 76:117-129.
    • (1994) Cell , vol.76 , pp. 117-129
    • Westaway, D.1
  • 30
    • 38049170554 scopus 로고    scopus 로고
    • Prion detection by an amyloid seeding assay
    • Colby DW, et al. (2007) Prion detection by an amyloid seeding assay. Proc Natl Acad Sci USA 104:20914-20919.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20914-20919
    • Colby, D.W.1
  • 31
    • 33746698975 scopus 로고    scopus 로고
    • The physical basis of how prion conformations determine strain phenotypes
    • Tanaka M, Collins SR, Toyama BH, Weissman JS (2006) The physical basis of how prion conformations determine strain phenotypes. Nature 442:585-589.
    • (2006) Nature , vol.442 , pp. 585-589
    • Tanaka, M.1    Collins, S.R.2    Toyama, B.H.3    Weissman, J.S.4
  • 32
    • 0344222186 scopus 로고    scopus 로고
    • Selective neuronal targeting in prion disease
    • DeArmond SJ, et al. (1997) Selective neuronal targeting in prion disease. Neuron 19:1337-1348.
    • (1997) Neuron , vol.19 , pp. 1337-1348
    • DeArmond, S.J.1
  • 33
    • 43249086837 scopus 로고    scopus 로고
    • Host PrP glycosylation: A major factor determining the outcome of prion infection
    • Tuzi NL, et al. (2008) Host PrP glycosylation: A major factor determining the outcome of prion infection. PLoS Biol 6:e100.
    • (2008) PLoS Biol , vol.6
    • Tuzi, N.L.1
  • 34
    • 66149098220 scopus 로고    scopus 로고
    • Prion protein glycosylation is not required for strain-specific neurotropism
    • Piro JR, et al. (2009) Prion protein glycosylation is not required for strain-specific neurotropism. J Virol 83:5321-5328.
    • (2009) J Virol , vol.83 , pp. 5321-5328
    • Piro, J.R.1
  • 36
    • 0342579567 scopus 로고
    • Cataloguing post-translational modifications of the scrapie prion protein by mass spectrometry
    • eds Prusiner SB, Collinge J, Powell J, Anderton B Ellis Horwood, London, pp
    • Stahl N, et al. (1992) Cataloguing post-translational modifications of the scrapie prion protein by mass spectrometry. Prion Diseases of Humans and Animals, eds Prusiner SB, Collinge J, Powell J, Anderton B (Ellis Horwood, London), pp 361-379.
    • (1992) Prion Diseases of Humans and Animals , pp. 361-379
    • Stahl, N.1
  • 37
  • 38
    • 0021989356 scopus 로고
    • Competition between strains of scrapie depends on the blocking agent being infectious
    • Kimberlin RH, Walker CA (1985) Competition between strains of scrapie depends on the blocking agent being infectious. Intervirology 23:74-81.
    • (1985) Intervirology , vol.23 , pp. 74-81
    • Kimberlin, R.H.1    Walker, C.A.2
  • 39
    • 62449089908 scopus 로고    scopus 로고
    • Prion interference with multiple prion isolates
    • Schutt CR, Bartz JC (2008) Prion interference with multiple prion isolates. Prion 2:61-63.
    • (2008) Prion , vol.2 , pp. 61-63
    • Schutt, C.R.1    Bartz, J.C.2
  • 41
    • 2942722444 scopus 로고    scopus 로고
    • Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers
    • Shorter J, Lindquist S (2004) Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers. Science 304:1793-1797.
    • (2004) Science , vol.304 , pp. 1793-1797
    • Shorter, J.1    Lindquist, S.2
  • 42
    • 3943084181 scopus 로고    scopus 로고
    • Emerging principles of conformation-based prion inheritance
    • Chien P, Weissman JS, DePace AH (2004) Emerging principles of conformation-based prion inheritance. Annu Rev Biochem 73:617-656.
    • (2004) Annu Rev Biochem , vol.73 , pp. 617-656
    • Chien, P.1    Weissman, J.S.2    DePace, A.H.3
  • 43
    • 0028882424 scopus 로고
    • Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
    • Telling GC, et al. (1995) Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 83:79-90.
    • (1995) Cell , vol.83 , pp. 79-90
    • Telling, G.C.1
  • 44
    • 0036791019 scopus 로고    scopus 로고
    • Dominant-negative inhibition of prion replication in transgenic mice
    • Perrier V, et al. (2002) Dominant-negative inhibition of prion replication in transgenic mice. Proc Natl Acad Sci USA 99:13079-13084.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13079-13084
    • Perrier, V.1
  • 45
    • 0028338441 scopus 로고
    • Structural clues to prion replication
    • Cohen FE, et al. (1994) Structural clues to prion replication. Science 264:530-531.
    • (1994) Science , vol.264 , pp. 530-531
    • Cohen, F.E.1
  • 46
    • 33749020837 scopus 로고    scopus 로고
    • Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host
    • Meyer-Luehmann M, et al. (2006) Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science 313:1781-1784.
    • (2006) Science , vol.313 , pp. 1781-1784
    • Meyer-Luehmann, M.1
  • 47
    • 43249114934 scopus 로고    scopus 로고
    • Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
    • Kordower JH, Chu Y, Hauser RA, Freeman TB, Olanow CW (2008) Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat Med 14:504-506.
    • (2008) Nat Med , vol.14 , pp. 504-506
    • Kordower, J.H.1    Chu, Y.2    Hauser, R.A.3    Freeman, T.B.4    Olanow, C.W.5
  • 48
    • 43249110200 scopus 로고    scopus 로고
    • Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
    • Li JY, et al. (2008) Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation. Nat Med 14:501-503.
    • (2008) Nat Med , vol.14 , pp. 501-503
    • Li, J.Y.1
  • 49
    • 0019479696 scopus 로고
    • Determination of scrapie agent titer from incubation period measurements in hamsters
    • eds Streilein JW, Hart DA, Stein-Streilein J, Duncan WR, Billingham RE Plenum Press, New York, pp
    • Prusiner SB, Cochran SP, Downey DE, Groth DF (1981) Determination of scrapie agent titer from incubation period measurements in hamsters. Hamster Immune Responses in Infectious and Oncologic Diseases, eds Streilein JW, Hart DA, Stein-Streilein J, Duncan WR, Billingham RE (Plenum Press, New York), pp 385-399.
    • (1981) Hamster Immune Responses in Infectious and Oncologic Diseases , pp. 385-399
    • Prusiner, S.B.1    Cochran, S.P.2    Downey, D.E.3    Groth, D.F.4
  • 50
    • 0017873041 scopus 로고
    • Pathogenesis of mouse scrapie: Effect of route of inoculation on infectivity titres and dose-response curves
    • Kimberlin RH, Walker CA (1978) Pathogenesis of mouse scrapie: Effect of route of inoculation on infectivity titres and dose-response curves. J Comp Pathol 88:39-47.
    • (1978) J Comp Pathol , vol.88 , pp. 39-47
    • Kimberlin, R.H.1    Walker, C.A.2
  • 51
    • 0023467393 scopus 로고
    • Distinct prion proteins in short and long scrapie incubation period mice
    • Westaway D, et al. (1987) Distinct prion proteins in short and long scrapie incubation period mice. Cell 51:651-662.
    • (1987) Cell , vol.51 , pp. 651-662
    • Westaway, D.1
  • 52
    • 33748483636 scopus 로고    scopus 로고
    • Transmission of elk and deer prions to transgenic mice
    • Tamgüney G, et al. (2006) Transmission of elk and deer prions to transgenic mice. J Virol 80:9104-9114.
    • (2006) J Virol , vol.80 , pp. 9104-9114
    • Tamgüney, G.1
  • 53
    • 15844419908 scopus 로고    scopus 로고
    • High-level expression and characterization of a purified 142-residue polypeptide of the prion protein
    • Mehlhorn I, et al. (1996) High-level expression and characterization of a purified 142-residue polypeptide of the prion protein. Biochemistry 35:5528-5537.
    • (1996) Biochemistry , vol.35 , pp. 5528-5537
    • Mehlhorn, I.1
  • 54
    • 0036843448 scopus 로고    scopus 로고
    • Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice
    • Safar JG, et al. (2002) Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice. Nat Biotechnol 20:1147-1150.
    • (2002) Nat Biotechnol , vol.20 , pp. 1147-1150
    • Safar, J.G.1


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