A synthetic peptide initiates Gerstmann-Straussler-Scheinker (GSS) disease in transgenic mice

Journal of Molecular Biology

Volumn 295, Issue 4, 2000, Pages 997-1007

  Kaneko, Kiyotoshi ^a,c   Ball, Haydn L ^a   Wille, Holger ^a   Zhang, Hong ^a   Groth, Darlene ^a   Torchia, Marilyn ^a   Tremblay, Patrick ^a   Safar, Jiri ^a   Prusiner, Stanley B ^a   DeArmond, Stephen J ^a,b   Baldwin, Michael A ^b   Cohen, Fred E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

Gerstmann Straussler Scheinker (GSS) disease; Prion protein synthetic peptide; PrP amyloid plaques; PrP mutation (P102L); pleated sheet

Indexed keywords

AMYLOID PROTEIN; MUTANT PROTEIN; PRION PROTEIN; SYNTHETIC PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; GERSTMANN STRAUSSLER SCHEINKER SYNDROME; HISTOPATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; TRANSGENIC MOUSE;

EID: 0034723133     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3386     Document Type: Article

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