Mutant PrPSc Conformers Induced by a Synthetic Peptide and Several Prion Strains

Journal of Virology

Volumn 78, Issue 4, 2004, Pages 2088-2099

  Tremblay, Patrick ^a,b,c   Ball, Haydn L ^a,b,d   Kaneko, Kiyotoshi ^a,e   Groth, Darlene ^a   Hegde, Ramanujan S ^b,f   Cohen, Fred E ^a,b   DeArmond, Stephen J ^a,b   Prusiner, Stanley B ^a,b   Safar, Jiri G ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Neurochem Inc   (Canada)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^f NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN EXTRACT; MUTANT PROTEIN; PRION PROTEIN; PROTEINASE; SYNTHETIC PEPTIDE; PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA SHEET; BIOACCUMULATION; BRAIN LEVEL; CONTROLLED STUDY; DISEASE COURSE; DOMINANT INHERITANCE; GENE EXPRESSION; GENE MUTATION; GERSTMANN STRAUSSLER SCHEINKER SYNDROME; HISTOPATHOLOGY; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; MOUSE; MOUSE STRAIN; NERVE DEGENERATION; NONHUMAN; PRION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FOLDING; STRUCTURE ANALYSIS; TRANSGENIC MOUSE; VIRUS STRAIN; VIRUS TRANSMISSION; ANIMAL; BRAIN; C57BL MOUSE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOGENICITY; PATHOLOGY; PRION DISEASE; SYNTHESIS;

ANIMALS; BRAIN; ENDOPEPTIDASES; GERSTMANN-STRAUSSLER-SCHEINKER DISEASE; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PEPTIDES; PRION DISEASES; PRIONS; PROTEIN CONFORMATION; PROTEIN FOLDING; PRPSC PROTEINS;

EID: 0842304471     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.4.2088-2099.2004     Document Type: Article

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