Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice

Nature Biotechnology

Volumn 20, Issue 11, 2002, Pages 1147-1150

  Safar, Jiri G ^a,b   Scott, Michael ^a,b   Monaghan, Jeff ^a   Deering, Camille ^a   Didorenko, Svetlana ^a   Vergara, Julie ^a   Ball, Haydn ^a   Legname, Giuseppe ^a   Leclerc, Estelle ^c   Solforosi, Laura ^c   Serban, Hana ^a   Groth, Darlene ^a   Burton, Dennis R ^c   Prusiner, Stanley B ^a,b   Williamson, R Anthony ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; BRAIN STEM; CATTLE; CHRONIC WASTING DISEASE; CLASSIFICATION; CREUTZFELDT JAKOB DISEASE; DEER; DISEASE CARRIER; DISEASE TRANSMISSION; EVALUATION; HUMAN; IMMUNOASSAY; INSTRUMENTATION; METABOLISM; METHODOLOGY; MOUSE; PRION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPECIES DIFFERENCE; TRANSGENIC MOUSE; ZOONOSIS; ANIMAL DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGEN RECOGNITION; BINDING AFFINITY; CONFORMATION; CONTROLLED STUDY; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; LIVESTOCK; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DENATURATION; RED DEER; WASTING SYNDROME;

ANIMALS; BRAIN STEM; CATTLE; CREUTZFELDT-JAKOB SYNDROME; DEER; DISEASE RESERVOIRS; DISEASE VECTORS; ENCEPHALOPATHY, BOVINE SPONGIFORM; HUMANS; IMMUNOASSAY; MICE; MICE, TRANSGENIC; PRIONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECIES SPECIFICITY; WASTING DISEASE, CHRONIC; ZOONOSES;

ANTIGEN-ANTIBODY REACTIONS; BIOASSAY; BIODIVERSITY; BRAIN; DISEASES; PATHOLOGY; PROTEINS;

CHRONIC WASTING DISEASE (CWD);

BIOTECHNOLOGY;

ISOPROTEIN; PRION PROTEIN; RECOMBINANT ANTIBODY;

EID: 0036843448     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt748     Document Type: Article

References (21)

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