메뉴 건너뛰기




Volumn 289, Issue 5479, 2000, Pages 595-599

Evidence for the prion hypothesis: Induction of the yeast [PSI+] factor by in vitro-converted Sup35 protein

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; FUNGAL PROTEIN; LIPOSOME; PRION PROTEIN;

EID: 0034725747     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.289.5479.595     Document Type: Article
Times cited : (140)

References (42)
  • 18
    • 0030712145 scopus 로고    scopus 로고
    • J. R. Glover et al., Cell 89, 811 (1997).
    • (1997) Cell , vol.89 , pp. 811
    • Glover, J.R.1
  • 20
    • 0033583190 scopus 로고    scopus 로고
    • G. S. Jackson et al., Science 283, 1935, (1999).
    • (1999) Science , vol.283 , pp. 1935
    • Jackson, G.S.1
  • 22
    • 0028997297 scopus 로고
    • R. A. Bessen et al., Nature 375, 698 (1995).
    • (1995) Nature , vol.375 , pp. 698
    • Bessen, R.A.1
  • 24
    • 0343894187 scopus 로고    scopus 로고
    • Supplemental Web material is available at Science Online at www.sciencemag.org/feature/data/1050406.shl.
    • Science
  • 25
    • 0343458456 scopus 로고    scopus 로고
    • note
    • At a concentration of 200 μg/ml, a 400-nm liposome contains ∼200 molecules of Sup35p. By comparison, the endogenous concentration of Sup35p is at least 20-fold less than that of ribosomes, which are present at ∼200,000 copies per yeast cell. See (35) for an estimate of ribosomes per yeast cell and (36, 37) for a quantification of Sup35p relative to ribosomes.
  • 29
    • 0343458454 scopus 로고    scopus 로고
    • note
    • +] formation (39).
  • 40
  • 42
    • 0343894179 scopus 로고    scopus 로고
    • note
    • We thank L. Gagne and M. Springer for assistance in liposome preparation and microscopy and F. E. Cohen, P. S. Kim, E. O'Shea, and members of the Lim and Weissman lab for helpful discussions. Supported by the NIH, the Searle Scholars Program, the David and Lucile Packard Foundation, and a postdoctoral fellowship from the European Molecular Biology Organization (H.E.S.).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.