-
1
-
-
0029945201
-
Beta-carotene, carotenoids, and disease prevention in humans
-
Mayne, S.T. (1996) Beta-carotene, carotenoids, and disease prevention in humans. Faseb J., 10, 690-701.
-
(1996)
Faseb J.
, vol.10
, pp. 690-701
-
-
Mayne, S.T.1
-
2
-
-
0023464342
-
Free radical tissue damage: protective role of antioxidant nutrients
-
Machlin, L.J. et al. (1987) Free radical tissue damage: protective role of antioxidant nutrients. Faseb J., 1, 441-445.
-
(1987)
Faseb J.
, vol.1
, pp. 441-445
-
-
Machlin, L.J.1
-
3
-
-
10344238570
-
Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance
-
Albanes, D. et al. (1996) Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance. J. Natl Cancer Inst., 88, 1560-1570.
-
(1996)
J. Natl Cancer Inst.
, vol.88
, pp. 1560-1570
-
-
Albanes, D.1
-
4
-
-
0038692733
-
Risk factors for lung cancer and for intervention effects in CARET, the beta-carotene and retinol efficacy trial
-
Omenn, G.S. et al. (1996) Risk factors for lung cancer and for intervention effects in CARET, the beta-carotene and retinol efficacy trial. J. Natl Cancer Inst., 88, 1550-1559.
-
(1996)
J. Natl Cancer Inst.
, vol.88
, pp. 1550-1559
-
-
Omenn, G.S.1
-
5
-
-
0345157579
-
Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease
-
Hennekens, C.H. et al. (1996) Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N. Engl. J. Med., 334, 1145-1149.
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 1145-1149
-
-
Hennekens, C.H.1
-
6
-
-
34248659644
-
The relationship between biomarkers of oxidative DNA damage, polycyclic aromatic hydrocarbon DNA adducts, antioxidant status and genetic susceptibility following exposure to environmental air pollution in humans
-
Singh, R. et al. (2007) The relationship between biomarkers of oxidative DNA damage, polycyclic aromatic hydrocarbon DNA adducts, antioxidant status and genetic susceptibility following exposure to environmental air pollution in humans. Mutat. Res., 620, 83-92.
-
(2007)
Mutat. Res.
, vol.620
, pp. 83-92
-
-
Singh, R.1
-
7
-
-
0029806936
-
Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53
-
Denissenko, M.F. et al. (1996) Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53. Science, 274, 430-432.
-
(1996)
Science
, vol.274
, pp. 430-432
-
-
Denissenko, M.F.1
-
8
-
-
0027247805
-
Oxidants in cigarette smoke
-
Ann. N. Y. Acad. Sci. (discussion 27-28)
-
Pryor, W.A. et al. (1993) Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Ann. N.Y. Acad. Sci., 686, 12-27; (discussion 27-28).
-
(1993)
Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite
, vol.686
, pp. 12-27
-
-
Pryor, W.A.1
-
9
-
-
0036632411
-
Chemoprevention of lung cancer by non-steroidal anti-inflammatory drugs among cigarette smokers
-
Harris, R.E. et al. (2002) Chemoprevention of lung cancer by non-steroidal anti-inflammatory drugs among cigarette smokers. Oncol. Rep., 9, 693-695.
-
(2002)
Oncol. Rep.
, vol.9
, pp. 693-695
-
-
Harris, R.E.1
-
10
-
-
0037378597
-
Risk of lung carcinoma among users of nonsteroidal antiinflammatory drugs
-
Muscat, J.E. et al. (2003) Risk of lung carcinoma among users of nonsteroidal antiinflammatory drugs. Cancer, 97, 1732-1736.
-
(2003)
Cancer
, vol.97
, pp. 1732-1736
-
-
Muscat, J.E.1
-
11
-
-
43149108399
-
Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker?
-
Loft, S. et al. (2008) Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker? Eur. J. Nutr., 47 (suppl. 2), 19-28.
-
(2008)
Eur. J. Nutr.
, vol.47
, Issue.SUPPL. 2
, pp. 19-28
-
-
Loft, S.1
-
12
-
-
18144452679
-
Oxy radicals, lipid peroxidation and DNA damage
-
Marnett, L.J. (2002) Oxy radicals, lipid peroxidation and DNA damage. Toxicology, 181-182, 219-222.
-
(2002)
Toxicology
, vol.181-182
, pp. 219-222
-
-
Marnett, L.J.1
-
13
-
-
0142216405
-
Prooxidant effects of beta-carotene in cultured cells
-
Palozza, P. et al. (2003) Prooxidant effects of beta-carotene in cultured cells. Mol. Aspects Med., 24, 353-362.
-
(2003)
Mol. Aspects Med.
, vol.24
, pp. 353-362
-
-
Palozza, P.1
-
14
-
-
38049023620
-
Changes in DNA repair during aging
-
Gorbunova, V. et al. (2007) Changes in DNA repair during aging. Nucleic Acids Res., 35, 7466-7474.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 7466-7474
-
-
Gorbunova, V.1
-
15
-
-
0041731614
-
Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells
-
Niedernhofer, L.J. et al. (2003) Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells. J. Biol. Chem., 278, 31426-31433.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31426-31433
-
-
Niedernhofer, L.J.1
-
16
-
-
0026536942
-
Beta-carotene uptake and tissue distribution in ferrets (Mustela putorius furo)
-
Gugger, E.T. et al. (1992) Beta-carotene uptake and tissue distribution in ferrets (Mustela putorius furo). J. Nutr., 122, 115-119.
-
(1992)
J. Nutr.
, vol.122
, pp. 115-119
-
-
Gugger, E.T.1
-
17
-
-
0026803337
-
Intestinal uptake and lymphatic absorption of beta-carotene in ferrets: a model for human beta-carotene metabolism
-
Wang, X.D. et al. (1992) Intestinal uptake and lymphatic absorption of beta-carotene in ferrets: a model for human beta-carotene metabolism. Am. J. Physiol., 263, G480-G486.
-
(1992)
Am. J. Physiol.
, vol.263
-
-
Wang, X.D.1
-
18
-
-
0034026977
-
Effects of supplemental alpha-tocopherol and beta-carotene on colorectal cancer: results from a controlled trial (Finland)
-
Albanes, D. et al. (2000) Effects of supplemental alpha-tocopherol and beta-carotene on colorectal cancer: results from a controlled trial (Finland). Cancer Causes Control, 11, 197-205.
-
(2000)
Cancer Causes Control
, vol.11
, pp. 197-205
-
-
Albanes, D.1
-
19
-
-
20444502846
-
Human intestinal and lung cell lines exposed to beta-carotene show a large variation in intracellular levels of beta-carotene and its metabolites
-
Franssen-van Hal, N.L. et al. (2005) Human intestinal and lung cell lines exposed to beta-carotene show a large variation in intracellular levels of beta-carotene and its metabolites. Arch. Biochem. Biophys., 439, 32-41.
-
(2005)
Arch. Biochem. Biophys.
, vol.439
, pp. 32-41
-
-
Franssen-van Hal, N.L.1
-
20
-
-
0034521543
-
Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets
-
Liu, C. et al. (2000) Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets. Carcinogenesis, 21, 2245-2253.
-
(2000)
Carcinogenesis
, vol.21
, pp. 2245-2253
-
-
Liu, C.1
-
21
-
-
41949140719
-
Effects of 6-month daily supplementation with oral beta-carotene in combination or not with benzo[a]pyrene on cell-cycle markers in the lung of ferrets
-
Fuster, A. et al. (2008) Effects of 6-month daily supplementation with oral beta-carotene in combination or not with benzo[a]pyrene on cell-cycle markers in the lung of ferrets. J. Nutr. Biochem., 19, 295-304.
-
(2008)
J. Nutr. Biochem.
, vol.19
, pp. 295-304
-
-
Fuster, A.1
-
22
-
-
1342331923
-
32P-postlabeling method for analyzing the malondialdehyde-deoxyguanosine adduct, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-pyrimido[1,2-alpha]purin-10(3H )one in human tissue samples
-
32P-postlabeling method for analyzing the malondialdehyde-deoxyguanosine adduct, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-pyrimido[1,2-alpha]purin-10(3H )one in human tissue samples. Chem. Res. Toxicol., 17, 268-272.
-
(2004)
Chem. Res. Toxicol.
, vol.17
, pp. 268-272
-
-
Sun, X.1
-
23
-
-
0031721679
-
Determination of malondialdehyde-induced DNA damage in human tissues using an immunoslot blot assay
-
Leuratti, C. et al. (1998) Determination of malondialdehyde-induced DNA damage in human tissues using an immunoslot blot assay. Carcinogenesis, 19, 1919-1924.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1919-1924
-
-
Leuratti, C.1
-
24
-
-
0026552871
-
32P-postlabelling
-
32P-postlabelling. Carcinogenesis, 13, 593-599.
-
(1992)
Carcinogenesis
, vol.13
, pp. 593-599
-
-
Vaca, C.E.1
-
25
-
-
33749172210
-
Bronchial malondialdehyde DNA adducts, tobacco smoking, and lung cancer
-
Munnia, A. et al. (2006) Bronchial malondialdehyde DNA adducts, tobacco smoking, and lung cancer. Free Radic. Biol. Med., 41, 1499-1505.
-
(2006)
Free Radic. Biol. Med.
, vol.41
, pp. 1499-1505
-
-
Munnia, A.1
-
26
-
-
36048941319
-
32P-Post-labelling method improvements for aromatic compound-related molecular epidemiology studies
-
32P-Post-labelling method improvements for aromatic compound-related molecular epidemiology studies. Mutagenesis, 22, 381-385.
-
(2007)
Mutagenesis
, vol.22
, pp. 381-385
-
-
Munnia, A.1
-
27
-
-
0031217641
-
Neutrophils amplify the formation of DNA adducts by benzo[a]pyrene in lung target cells
-
Borm, P.J. et al. (1997) Neutrophils amplify the formation of DNA adducts by benzo[a]pyrene in lung target cells. Environ. Health Perspect., 105 (suppl. 5), 1089-1093.
-
(1997)
Environ. Health Perspect.
, vol.105
, Issue.SUPPL. 5
, pp. 1089-1093
-
-
Borm, P.J.1
-
28
-
-
58149190499
-
Comet assay-based methods for measuring DNA repair in vitro; estimates of inter-and intra-individual variation
-
Gaivao, I. et al. (2009) Comet assay-based methods for measuring DNA repair in vitro; estimates of inter-and intra-individual variation. Cell Biol. Toxicol., 25, 45-52.
-
(2009)
Cell Biol. Toxicol.
, vol.25
, pp. 45-52
-
-
Gaivao, I.1
-
29
-
-
58049087184
-
Beta-carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells
-
van Helden, Y.G. et al. (2009) Beta-carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells. Free Radic. Biol. Med., 46, 299-304.
-
(2009)
Free Radic. Biol. Med.
, vol.46
, pp. 299-304
-
-
van Helden, Y.G.1
-
30
-
-
0036802116
-
Characterization of the initial carbon-centered pentadienyl radical and subsequent radicals in lipid peroxidation: identification via on-line high performance liquid chromatography/electron spin resonance and mass spectrometry
-
Yue Qian, S. et al. (2002) Characterization of the initial carbon-centered pentadienyl radical and subsequent radicals in lipid peroxidation: identification via on-line high performance liquid chromatography/electron spin resonance and mass spectrometry. Free Radic. Biol. Med., 33, 998-1009.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 998-1009
-
-
Yue Qian, S.1
-
31
-
-
0025173324
-
Hydroxyl radical is not a product of the reaction of xanthine oxidase and xanthine
-
J. Biol. Chem.
-
Britigan, B.E. et al. (1990) Hydroxyl radical is not a product of the reaction of xanthine oxidase and xanthine. The confounding problem of adventitious iron bound to xanthine oxidase. J. Biol. Chem., 265, 17533-17538.
-
(1990)
The confounding problem of adventitious iron bound to xanthine oxidase
, vol.265
, pp. 17533-17538
-
-
Britigan, B.E.1
-
32
-
-
26844552571
-
beta-carotene: friend or foe?
-
Omaye, S.T. et al. (1997) beta-carotene: friend or foe? Fundam. Appl. Toxicol., 40, 163-174.
-
(1997)
Fundam. Appl. Toxicol.
, vol.40
, pp. 163-174
-
-
Omaye, S.T.1
-
33
-
-
0034775553
-
Antioxidant and prooxidant properties of carotenoids
-
Young, A.J. et al. (2001) Antioxidant and prooxidant properties of carotenoids. Arch. Biochem. Biophys., 385, 20-27.
-
(2001)
Arch. Biochem. Biophys.
, vol.385
, pp. 20-27
-
-
Young, A.J.1
-
34
-
-
37349018634
-
beta-Carotene and canthaxanthin alter the prooxidation and antioxidation balance in rats fed a high-cholesterol and high-fat diet
-
Shih, C.K. et al. (2008) beta-Carotene and canthaxanthin alter the prooxidation and antioxidation balance in rats fed a high-cholesterol and high-fat diet. Br. J. Nutr., 99, 59-66.
-
(2008)
Br. J. Nutr.
, vol.99
, pp. 59-66
-
-
Shih, C.K.1
-
35
-
-
28644445300
-
Cyto-and genotoxic potential of beta-carotene and cleavage products under oxidative stress
-
Alija, A.J. et al. (2005) Cyto-and genotoxic potential of beta-carotene and cleavage products under oxidative stress. Biofactors, 24, 159-163.
-
(2005)
Biofactors
, vol.24
, pp. 159-163
-
-
Alija, A.J.1
-
36
-
-
0033038856
-
Lycopene and beta-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses
-
Lowe, G.M. et al. (1999) Lycopene and beta-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses. Free Radic. Res., 30, 141-151.
-
(1999)
Free Radic. Res.
, vol.30
, pp. 141-151
-
-
Lowe, G.M.1
-
37
-
-
0036675753
-
Beta-carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration
-
Siems, W. et al. (2002) Beta-carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration. Faseb J., 16, 1289-1291.
-
(2002)
Faseb J.
, vol.16
, pp. 1289-1291
-
-
Siems, W.1
-
38
-
-
21344441240
-
Beta-carotene breakdown products may impair mitochondrial functions-potential side effects of high-dose beta-carotene supplementation
-
Siems, W. et al. (2005) Beta-carotene breakdown products may impair mitochondrial functions-potential side effects of high-dose beta-carotene supplementation. J. Nutr. Biochem., 16, 385-397.
-
(2005)
J. Nutr. Biochem.
, vol.16
, pp. 385-397
-
-
Siems, W.1
-
39
-
-
0034011261
-
Oxyradicals and DNA damage
-
Marnett, L.J. (2000) Oxyradicals and DNA damage. Carcinogenesis, 21, 361-370.
-
(2000)
Carcinogenesis
, vol.21
, pp. 361-370
-
-
Marnett, L.J.1
-
40
-
-
0029891651
-
Determination of DNA adducts of malonaldehyde in humans: effects of dietary fatty acid composition
-
Fang, J.L. et al. (1996) Determination of DNA adducts of malonaldehyde in humans: effects of dietary fatty acid composition. Carcinogenesis, 17, 1035-1040.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1035-1040
-
-
Fang, J.L.1
-
41
-
-
0030747309
-
High dietary omega-6 polyunsaturated fatty acids drastically increase the formation of etheno-DNA base adducts in white blood cells of female subjects
-
Nair, J. et al. (1997) High dietary omega-6 polyunsaturated fatty acids drastically increase the formation of etheno-DNA base adducts in white blood cells of female subjects. Cancer Epidemiol. Biomarkers Prev., 6, 597-601.
-
(1997)
Cancer Epidemiol. Biomarkers Prev.
, vol.6
, pp. 597-601
-
-
Nair, J.1
-
42
-
-
0032530416
-
Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal
-
Dedon, P.C. et al. (1998) Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal. Proc. Natl Acad. Sci. USA, 95, 11113-11116.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 11113-11116
-
-
Dedon, P.C.1
-
43
-
-
21844432111
-
Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA
-
Zhou, X. et al. (2005) Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA. J. Biol. Chem., 280, 25377-25382.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 25377-25382
-
-
Zhou, X.1
-
44
-
-
25144433702
-
Formation of M1G-dR from endogenous and exogenous ROS-inducing chemicals
-
Jeong, Y.C. et al. (2005) Formation of M1G-dR from endogenous and exogenous ROS-inducing chemicals. Free Radic. Biol. Med., 39, 1021-1029.
-
(2005)
Free Radic. Biol. Med.
, vol.39
, pp. 1021-1029
-
-
Jeong, Y.C.1
-
45
-
-
0029966118
-
Absorption, metabolism, and transport of carotenoids
-
Parker, R.S. (1996) Absorption, metabolism, and transport of carotenoids. Faseb J., 10, 542-551.
-
(1996)
Faseb J.
, vol.10
, pp. 542-551
-
-
Parker, R.S.1
-
46
-
-
20444427216
-
Can beta-carotene regulate cell growth by a redox mechanism? An answer from cultured cells
-
Palozza, P. (2005) Can beta-carotene regulate cell growth by a redox mechanism? An answer from cultured cells. Biochim. Biophys. Acta, 1740, 215-221.
-
(2005)
Biochim. Biophys. Acta
, vol.1740
, pp. 215-221
-
-
Palozza, P.1
-
47
-
-
33845361126
-
Dual role of beta-carotene in combination with cigarette smoke aqueous extract on the formation of mutagenic lipid peroxidation products in lung membranes: dependence on pO2
-
Palozza, P. et al. (2006) Dual role of beta-carotene in combination with cigarette smoke aqueous extract on the formation of mutagenic lipid peroxidation products in lung membranes: dependence on pO2. Carcinogenesis, 27, 2383-2391.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2383-2391
-
-
Palozza, P.1
-
48
-
-
0031669520
-
Prooxidant actions of carotenoids in biologic systems
-
Palozza, P. (1998) Prooxidant actions of carotenoids in biologic systems. Nutr. Rev., 56, 257-265.
-
(1998)
Nutr. Rev.
, vol.56
, pp. 257-265
-
-
Palozza, P.1
-
49
-
-
0038239638
-
Carotenoid-radical interactions
-
Krinsky, N.I. et al. (2003) Carotenoid-radical interactions. Biochem. Biophys. Res. Commun., 305, 754-760.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.305
, pp. 754-760
-
-
Krinsky, N.I.1
-
50
-
-
5044245540
-
In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism
-
Briede, J.J. et al. (2004) In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism. Free Radic. Res., 38, 995-1002.
-
(2004)
Free Radic. Res.
, vol.38
, pp. 995-1002
-
-
Briede, J.J.1
-
51
-
-
0025147459
-
Nature's chemicals and synthetic chemicals: comparative toxicology
-
Ames, B.N. et al. (1990) Nature's chemicals and synthetic chemicals: comparative toxicology. Proc. Natl Acad. Sci. USA, 87, 7782-7786.
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 7782-7786
-
-
Ames, B.N.1
-
52
-
-
28944433823
-
Influence of environmental exposure to PAHs on the susceptibility of lymphocytes to DNA-damage induction and on their repair capacity
-
Cebulska-Wasilewska, A. et al. (2005) Influence of environmental exposure to PAHs on the susceptibility of lymphocytes to DNA-damage induction and on their repair capacity. Mutat. Res., 588, 73-81.
-
(2005)
Mutat. Res.
, vol.588
, pp. 73-81
-
-
Cebulska-Wasilewska, A.1
-
53
-
-
33751022467
-
DNA damage and repair capacity by comet assay in lymphocytes of white-collar active smokers and passive smokers (non-and ex-smokers) at workplace
-
Fracasso, M.E. et al. (2006) DNA damage and repair capacity by comet assay in lymphocytes of white-collar active smokers and passive smokers (non-and ex-smokers) at workplace. Toxicol. Lett., 167, 131-141.
-
(2006)
Toxicol. Lett.
, vol.167
, pp. 131-141
-
-
Fracasso, M.E.1
|