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Volumn 30, Issue 12, 2009, Pages 2070-2076

Beta-carotene affects oxidative stress-related DNA damage in lung epithelial cells and in ferret lung

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 DEOXY BETA DEXTRO ERYTHRO PENTAFURANOSYL)PYRIMIDOL[1,2 ALPHA]PURIN 10(3H) ONE DEOXYGUANOSINE; 8 HYDROXYDEOXYGUANOSINE; BENZO[A]PYRENE; BETA CAROTENE; DEOXYGUANOSINE; HYDROGEN PEROXIDE; UNCLASSIFIED DRUG; ANTIOXIDANT; DNA; HYDROXYL RADICAL; OXIDIZING AGENT;

EID: 73949133092     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp186     Document Type: Article
Times cited : (50)

References (53)
  • 1
    • 0029945201 scopus 로고    scopus 로고
    • Beta-carotene, carotenoids, and disease prevention in humans
    • Mayne, S.T. (1996) Beta-carotene, carotenoids, and disease prevention in humans. Faseb J., 10, 690-701.
    • (1996) Faseb J. , vol.10 , pp. 690-701
    • Mayne, S.T.1
  • 2
    • 0023464342 scopus 로고
    • Free radical tissue damage: protective role of antioxidant nutrients
    • Machlin, L.J. et al. (1987) Free radical tissue damage: protective role of antioxidant nutrients. Faseb J., 1, 441-445.
    • (1987) Faseb J. , vol.1 , pp. 441-445
    • Machlin, L.J.1
  • 3
    • 10344238570 scopus 로고    scopus 로고
    • Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance
    • Albanes, D. et al. (1996) Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance. J. Natl Cancer Inst., 88, 1560-1570.
    • (1996) J. Natl Cancer Inst. , vol.88 , pp. 1560-1570
    • Albanes, D.1
  • 4
    • 0038692733 scopus 로고    scopus 로고
    • Risk factors for lung cancer and for intervention effects in CARET, the beta-carotene and retinol efficacy trial
    • Omenn, G.S. et al. (1996) Risk factors for lung cancer and for intervention effects in CARET, the beta-carotene and retinol efficacy trial. J. Natl Cancer Inst., 88, 1550-1559.
    • (1996) J. Natl Cancer Inst. , vol.88 , pp. 1550-1559
    • Omenn, G.S.1
  • 5
    • 0345157579 scopus 로고    scopus 로고
    • Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease
    • Hennekens, C.H. et al. (1996) Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N. Engl. J. Med., 334, 1145-1149.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1145-1149
    • Hennekens, C.H.1
  • 6
    • 34248659644 scopus 로고    scopus 로고
    • The relationship between biomarkers of oxidative DNA damage, polycyclic aromatic hydrocarbon DNA adducts, antioxidant status and genetic susceptibility following exposure to environmental air pollution in humans
    • Singh, R. et al. (2007) The relationship between biomarkers of oxidative DNA damage, polycyclic aromatic hydrocarbon DNA adducts, antioxidant status and genetic susceptibility following exposure to environmental air pollution in humans. Mutat. Res., 620, 83-92.
    • (2007) Mutat. Res. , vol.620 , pp. 83-92
    • Singh, R.1
  • 7
    • 0029806936 scopus 로고    scopus 로고
    • Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53
    • Denissenko, M.F. et al. (1996) Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53. Science, 274, 430-432.
    • (1996) Science , vol.274 , pp. 430-432
    • Denissenko, M.F.1
  • 9
    • 0036632411 scopus 로고    scopus 로고
    • Chemoprevention of lung cancer by non-steroidal anti-inflammatory drugs among cigarette smokers
    • Harris, R.E. et al. (2002) Chemoprevention of lung cancer by non-steroidal anti-inflammatory drugs among cigarette smokers. Oncol. Rep., 9, 693-695.
    • (2002) Oncol. Rep. , vol.9 , pp. 693-695
    • Harris, R.E.1
  • 10
    • 0037378597 scopus 로고    scopus 로고
    • Risk of lung carcinoma among users of nonsteroidal antiinflammatory drugs
    • Muscat, J.E. et al. (2003) Risk of lung carcinoma among users of nonsteroidal antiinflammatory drugs. Cancer, 97, 1732-1736.
    • (2003) Cancer , vol.97 , pp. 1732-1736
    • Muscat, J.E.1
  • 11
    • 43149108399 scopus 로고    scopus 로고
    • Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker?
    • Loft, S. et al. (2008) Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker? Eur. J. Nutr., 47 (suppl. 2), 19-28.
    • (2008) Eur. J. Nutr. , vol.47 , Issue.SUPPL. 2 , pp. 19-28
    • Loft, S.1
  • 12
    • 18144452679 scopus 로고    scopus 로고
    • Oxy radicals, lipid peroxidation and DNA damage
    • Marnett, L.J. (2002) Oxy radicals, lipid peroxidation and DNA damage. Toxicology, 181-182, 219-222.
    • (2002) Toxicology , vol.181-182 , pp. 219-222
    • Marnett, L.J.1
  • 13
    • 0142216405 scopus 로고    scopus 로고
    • Prooxidant effects of beta-carotene in cultured cells
    • Palozza, P. et al. (2003) Prooxidant effects of beta-carotene in cultured cells. Mol. Aspects Med., 24, 353-362.
    • (2003) Mol. Aspects Med. , vol.24 , pp. 353-362
    • Palozza, P.1
  • 14
    • 38049023620 scopus 로고    scopus 로고
    • Changes in DNA repair during aging
    • Gorbunova, V. et al. (2007) Changes in DNA repair during aging. Nucleic Acids Res., 35, 7466-7474.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 7466-7474
    • Gorbunova, V.1
  • 15
    • 0041731614 scopus 로고    scopus 로고
    • Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells
    • Niedernhofer, L.J. et al. (2003) Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells. J. Biol. Chem., 278, 31426-31433.
    • (2003) J. Biol. Chem. , vol.278 , pp. 31426-31433
    • Niedernhofer, L.J.1
  • 16
    • 0026536942 scopus 로고
    • Beta-carotene uptake and tissue distribution in ferrets (Mustela putorius furo)
    • Gugger, E.T. et al. (1992) Beta-carotene uptake and tissue distribution in ferrets (Mustela putorius furo). J. Nutr., 122, 115-119.
    • (1992) J. Nutr. , vol.122 , pp. 115-119
    • Gugger, E.T.1
  • 17
    • 0026803337 scopus 로고
    • Intestinal uptake and lymphatic absorption of beta-carotene in ferrets: a model for human beta-carotene metabolism
    • Wang, X.D. et al. (1992) Intestinal uptake and lymphatic absorption of beta-carotene in ferrets: a model for human beta-carotene metabolism. Am. J. Physiol., 263, G480-G486.
    • (1992) Am. J. Physiol. , vol.263
    • Wang, X.D.1
  • 18
    • 0034026977 scopus 로고    scopus 로고
    • Effects of supplemental alpha-tocopherol and beta-carotene on colorectal cancer: results from a controlled trial (Finland)
    • Albanes, D. et al. (2000) Effects of supplemental alpha-tocopherol and beta-carotene on colorectal cancer: results from a controlled trial (Finland). Cancer Causes Control, 11, 197-205.
    • (2000) Cancer Causes Control , vol.11 , pp. 197-205
    • Albanes, D.1
  • 19
    • 20444502846 scopus 로고    scopus 로고
    • Human intestinal and lung cell lines exposed to beta-carotene show a large variation in intracellular levels of beta-carotene and its metabolites
    • Franssen-van Hal, N.L. et al. (2005) Human intestinal and lung cell lines exposed to beta-carotene show a large variation in intracellular levels of beta-carotene and its metabolites. Arch. Biochem. Biophys., 439, 32-41.
    • (2005) Arch. Biochem. Biophys. , vol.439 , pp. 32-41
    • Franssen-van Hal, N.L.1
  • 20
    • 0034521543 scopus 로고    scopus 로고
    • Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets
    • Liu, C. et al. (2000) Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets. Carcinogenesis, 21, 2245-2253.
    • (2000) Carcinogenesis , vol.21 , pp. 2245-2253
    • Liu, C.1
  • 21
    • 41949140719 scopus 로고    scopus 로고
    • Effects of 6-month daily supplementation with oral beta-carotene in combination or not with benzo[a]pyrene on cell-cycle markers in the lung of ferrets
    • Fuster, A. et al. (2008) Effects of 6-month daily supplementation with oral beta-carotene in combination or not with benzo[a]pyrene on cell-cycle markers in the lung of ferrets. J. Nutr. Biochem., 19, 295-304.
    • (2008) J. Nutr. Biochem. , vol.19 , pp. 295-304
    • Fuster, A.1
  • 22
    • 1342331923 scopus 로고    scopus 로고
    • 32P-postlabeling method for analyzing the malondialdehyde-deoxyguanosine adduct, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-pyrimido[1,2-alpha]purin-10(3H )one in human tissue samples
    • 32P-postlabeling method for analyzing the malondialdehyde-deoxyguanosine adduct, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-pyrimido[1,2-alpha]purin-10(3H )one in human tissue samples. Chem. Res. Toxicol., 17, 268-272.
    • (2004) Chem. Res. Toxicol. , vol.17 , pp. 268-272
    • Sun, X.1
  • 23
    • 0031721679 scopus 로고    scopus 로고
    • Determination of malondialdehyde-induced DNA damage in human tissues using an immunoslot blot assay
    • Leuratti, C. et al. (1998) Determination of malondialdehyde-induced DNA damage in human tissues using an immunoslot blot assay. Carcinogenesis, 19, 1919-1924.
    • (1998) Carcinogenesis , vol.19 , pp. 1919-1924
    • Leuratti, C.1
  • 24
    • 0026552871 scopus 로고
    • 32P-postlabelling
    • 32P-postlabelling. Carcinogenesis, 13, 593-599.
    • (1992) Carcinogenesis , vol.13 , pp. 593-599
    • Vaca, C.E.1
  • 25
    • 33749172210 scopus 로고    scopus 로고
    • Bronchial malondialdehyde DNA adducts, tobacco smoking, and lung cancer
    • Munnia, A. et al. (2006) Bronchial malondialdehyde DNA adducts, tobacco smoking, and lung cancer. Free Radic. Biol. Med., 41, 1499-1505.
    • (2006) Free Radic. Biol. Med. , vol.41 , pp. 1499-1505
    • Munnia, A.1
  • 26
    • 36048941319 scopus 로고    scopus 로고
    • 32P-Post-labelling method improvements for aromatic compound-related molecular epidemiology studies
    • 32P-Post-labelling method improvements for aromatic compound-related molecular epidemiology studies. Mutagenesis, 22, 381-385.
    • (2007) Mutagenesis , vol.22 , pp. 381-385
    • Munnia, A.1
  • 27
    • 0031217641 scopus 로고    scopus 로고
    • Neutrophils amplify the formation of DNA adducts by benzo[a]pyrene in lung target cells
    • Borm, P.J. et al. (1997) Neutrophils amplify the formation of DNA adducts by benzo[a]pyrene in lung target cells. Environ. Health Perspect., 105 (suppl. 5), 1089-1093.
    • (1997) Environ. Health Perspect. , vol.105 , Issue.SUPPL. 5 , pp. 1089-1093
    • Borm, P.J.1
  • 28
    • 58149190499 scopus 로고    scopus 로고
    • Comet assay-based methods for measuring DNA repair in vitro; estimates of inter-and intra-individual variation
    • Gaivao, I. et al. (2009) Comet assay-based methods for measuring DNA repair in vitro; estimates of inter-and intra-individual variation. Cell Biol. Toxicol., 25, 45-52.
    • (2009) Cell Biol. Toxicol. , vol.25 , pp. 45-52
    • Gaivao, I.1
  • 29
    • 58049087184 scopus 로고    scopus 로고
    • Beta-carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells
    • van Helden, Y.G. et al. (2009) Beta-carotene metabolites enhance inflammation-induced oxidative DNA damage in lung epithelial cells. Free Radic. Biol. Med., 46, 299-304.
    • (2009) Free Radic. Biol. Med. , vol.46 , pp. 299-304
    • van Helden, Y.G.1
  • 30
    • 0036802116 scopus 로고    scopus 로고
    • Characterization of the initial carbon-centered pentadienyl radical and subsequent radicals in lipid peroxidation: identification via on-line high performance liquid chromatography/electron spin resonance and mass spectrometry
    • Yue Qian, S. et al. (2002) Characterization of the initial carbon-centered pentadienyl radical and subsequent radicals in lipid peroxidation: identification via on-line high performance liquid chromatography/electron spin resonance and mass spectrometry. Free Radic. Biol. Med., 33, 998-1009.
    • (2002) Free Radic. Biol. Med. , vol.33 , pp. 998-1009
    • Yue Qian, S.1
  • 31
    • 0025173324 scopus 로고
    • Hydroxyl radical is not a product of the reaction of xanthine oxidase and xanthine
    • J. Biol. Chem.
    • Britigan, B.E. et al. (1990) Hydroxyl radical is not a product of the reaction of xanthine oxidase and xanthine. The confounding problem of adventitious iron bound to xanthine oxidase. J. Biol. Chem., 265, 17533-17538.
    • (1990) The confounding problem of adventitious iron bound to xanthine oxidase , vol.265 , pp. 17533-17538
    • Britigan, B.E.1
  • 32
    • 26844552571 scopus 로고    scopus 로고
    • beta-carotene: friend or foe?
    • Omaye, S.T. et al. (1997) beta-carotene: friend or foe? Fundam. Appl. Toxicol., 40, 163-174.
    • (1997) Fundam. Appl. Toxicol. , vol.40 , pp. 163-174
    • Omaye, S.T.1
  • 33
    • 0034775553 scopus 로고    scopus 로고
    • Antioxidant and prooxidant properties of carotenoids
    • Young, A.J. et al. (2001) Antioxidant and prooxidant properties of carotenoids. Arch. Biochem. Biophys., 385, 20-27.
    • (2001) Arch. Biochem. Biophys. , vol.385 , pp. 20-27
    • Young, A.J.1
  • 34
    • 37349018634 scopus 로고    scopus 로고
    • beta-Carotene and canthaxanthin alter the prooxidation and antioxidation balance in rats fed a high-cholesterol and high-fat diet
    • Shih, C.K. et al. (2008) beta-Carotene and canthaxanthin alter the prooxidation and antioxidation balance in rats fed a high-cholesterol and high-fat diet. Br. J. Nutr., 99, 59-66.
    • (2008) Br. J. Nutr. , vol.99 , pp. 59-66
    • Shih, C.K.1
  • 35
    • 28644445300 scopus 로고    scopus 로고
    • Cyto-and genotoxic potential of beta-carotene and cleavage products under oxidative stress
    • Alija, A.J. et al. (2005) Cyto-and genotoxic potential of beta-carotene and cleavage products under oxidative stress. Biofactors, 24, 159-163.
    • (2005) Biofactors , vol.24 , pp. 159-163
    • Alija, A.J.1
  • 36
    • 0033038856 scopus 로고    scopus 로고
    • Lycopene and beta-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses
    • Lowe, G.M. et al. (1999) Lycopene and beta-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses. Free Radic. Res., 30, 141-151.
    • (1999) Free Radic. Res. , vol.30 , pp. 141-151
    • Lowe, G.M.1
  • 37
    • 0036675753 scopus 로고    scopus 로고
    • Beta-carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration
    • Siems, W. et al. (2002) Beta-carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration. Faseb J., 16, 1289-1291.
    • (2002) Faseb J. , vol.16 , pp. 1289-1291
    • Siems, W.1
  • 38
    • 21344441240 scopus 로고    scopus 로고
    • Beta-carotene breakdown products may impair mitochondrial functions-potential side effects of high-dose beta-carotene supplementation
    • Siems, W. et al. (2005) Beta-carotene breakdown products may impair mitochondrial functions-potential side effects of high-dose beta-carotene supplementation. J. Nutr. Biochem., 16, 385-397.
    • (2005) J. Nutr. Biochem. , vol.16 , pp. 385-397
    • Siems, W.1
  • 39
    • 0034011261 scopus 로고    scopus 로고
    • Oxyradicals and DNA damage
    • Marnett, L.J. (2000) Oxyradicals and DNA damage. Carcinogenesis, 21, 361-370.
    • (2000) Carcinogenesis , vol.21 , pp. 361-370
    • Marnett, L.J.1
  • 40
    • 0029891651 scopus 로고    scopus 로고
    • Determination of DNA adducts of malonaldehyde in humans: effects of dietary fatty acid composition
    • Fang, J.L. et al. (1996) Determination of DNA adducts of malonaldehyde in humans: effects of dietary fatty acid composition. Carcinogenesis, 17, 1035-1040.
    • (1996) Carcinogenesis , vol.17 , pp. 1035-1040
    • Fang, J.L.1
  • 41
    • 0030747309 scopus 로고    scopus 로고
    • High dietary omega-6 polyunsaturated fatty acids drastically increase the formation of etheno-DNA base adducts in white blood cells of female subjects
    • Nair, J. et al. (1997) High dietary omega-6 polyunsaturated fatty acids drastically increase the formation of etheno-DNA base adducts in white blood cells of female subjects. Cancer Epidemiol. Biomarkers Prev., 6, 597-601.
    • (1997) Cancer Epidemiol. Biomarkers Prev. , vol.6 , pp. 597-601
    • Nair, J.1
  • 42
    • 0032530416 scopus 로고    scopus 로고
    • Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal
    • Dedon, P.C. et al. (1998) Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal. Proc. Natl Acad. Sci. USA, 95, 11113-11116.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 11113-11116
    • Dedon, P.C.1
  • 43
    • 21844432111 scopus 로고    scopus 로고
    • Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA
    • Zhou, X. et al. (2005) Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA. J. Biol. Chem., 280, 25377-25382.
    • (2005) J. Biol. Chem. , vol.280 , pp. 25377-25382
    • Zhou, X.1
  • 44
    • 25144433702 scopus 로고    scopus 로고
    • Formation of M1G-dR from endogenous and exogenous ROS-inducing chemicals
    • Jeong, Y.C. et al. (2005) Formation of M1G-dR from endogenous and exogenous ROS-inducing chemicals. Free Radic. Biol. Med., 39, 1021-1029.
    • (2005) Free Radic. Biol. Med. , vol.39 , pp. 1021-1029
    • Jeong, Y.C.1
  • 45
    • 0029966118 scopus 로고    scopus 로고
    • Absorption, metabolism, and transport of carotenoids
    • Parker, R.S. (1996) Absorption, metabolism, and transport of carotenoids. Faseb J., 10, 542-551.
    • (1996) Faseb J. , vol.10 , pp. 542-551
    • Parker, R.S.1
  • 46
    • 20444427216 scopus 로고    scopus 로고
    • Can beta-carotene regulate cell growth by a redox mechanism? An answer from cultured cells
    • Palozza, P. (2005) Can beta-carotene regulate cell growth by a redox mechanism? An answer from cultured cells. Biochim. Biophys. Acta, 1740, 215-221.
    • (2005) Biochim. Biophys. Acta , vol.1740 , pp. 215-221
    • Palozza, P.1
  • 47
    • 33845361126 scopus 로고    scopus 로고
    • Dual role of beta-carotene in combination with cigarette smoke aqueous extract on the formation of mutagenic lipid peroxidation products in lung membranes: dependence on pO2
    • Palozza, P. et al. (2006) Dual role of beta-carotene in combination with cigarette smoke aqueous extract on the formation of mutagenic lipid peroxidation products in lung membranes: dependence on pO2. Carcinogenesis, 27, 2383-2391.
    • (2006) Carcinogenesis , vol.27 , pp. 2383-2391
    • Palozza, P.1
  • 48
    • 0031669520 scopus 로고    scopus 로고
    • Prooxidant actions of carotenoids in biologic systems
    • Palozza, P. (1998) Prooxidant actions of carotenoids in biologic systems. Nutr. Rev., 56, 257-265.
    • (1998) Nutr. Rev. , vol.56 , pp. 257-265
    • Palozza, P.1
  • 49
    • 0038239638 scopus 로고    scopus 로고
    • Carotenoid-radical interactions
    • Krinsky, N.I. et al. (2003) Carotenoid-radical interactions. Biochem. Biophys. Res. Commun., 305, 754-760.
    • (2003) Biochem. Biophys. Res. Commun. , vol.305 , pp. 754-760
    • Krinsky, N.I.1
  • 50
    • 5044245540 scopus 로고    scopus 로고
    • In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism
    • Briede, J.J. et al. (2004) In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism. Free Radic. Res., 38, 995-1002.
    • (2004) Free Radic. Res. , vol.38 , pp. 995-1002
    • Briede, J.J.1
  • 51
    • 0025147459 scopus 로고
    • Nature's chemicals and synthetic chemicals: comparative toxicology
    • Ames, B.N. et al. (1990) Nature's chemicals and synthetic chemicals: comparative toxicology. Proc. Natl Acad. Sci. USA, 87, 7782-7786.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 7782-7786
    • Ames, B.N.1
  • 52
    • 28944433823 scopus 로고    scopus 로고
    • Influence of environmental exposure to PAHs on the susceptibility of lymphocytes to DNA-damage induction and on their repair capacity
    • Cebulska-Wasilewska, A. et al. (2005) Influence of environmental exposure to PAHs on the susceptibility of lymphocytes to DNA-damage induction and on their repair capacity. Mutat. Res., 588, 73-81.
    • (2005) Mutat. Res. , vol.588 , pp. 73-81
    • Cebulska-Wasilewska, A.1
  • 53
    • 33751022467 scopus 로고    scopus 로고
    • DNA damage and repair capacity by comet assay in lymphocytes of white-collar active smokers and passive smokers (non-and ex-smokers) at workplace
    • Fracasso, M.E. et al. (2006) DNA damage and repair capacity by comet assay in lymphocytes of white-collar active smokers and passive smokers (non-and ex-smokers) at workplace. Toxicol. Lett., 167, 131-141.
    • (2006) Toxicol. Lett. , vol.167 , pp. 131-141
    • Fracasso, M.E.1


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