β-carotene breakdown products may impair mitochondrial functions - Potential side effects of high-dose β-carotene supplementation

Journal of Nutritional Biochemistry

Volumn 16, Issue 7, 2005, Pages 385-397

  Siems, Werner ^a   Wiswedel, Ingrid ^b   Salerno, Costantino ^c   Crifò, Carlo ^c   Augustin, Wolfgang ^b   Schild, Lorenz ^b   Langhans, Claus Dieter ^d   Sommerburg, Olaf ^e  

^a Loges School of Physical Medicine   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e UNIVERSITY OF ULM   (Germany)

Author keywords

Carotene; Aldehydes; Antioxidant; Carotenoid; Carotenoid breakdown products; Free radicals; Lung; Malondialdehyde (MDA); Mitochondria; Neutrophils; Oxidative stress; Respiration

Indexed keywords

4 HYDROXYNONENAL; ALPHA CAROTENE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASTAXANTHIN; BETA CAROTENE; CANTHAXANTHIN; CAROTENOID; GAMMA CAROTENE; HYDROGEN PEROXIDE; HYPOCHLORITE; LYCOPENE; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE; PEROXYNITRITE; PHOSPHOLIPASE C; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE; RETINOL; SINGLET OXYGEN; THIOL DERIVATIVE; XANTHOPHYLL; ZEAXANTHIN;

APOPTOSIS; BRAIN MITOCHONDRION; CELL ACTIVATION; CELL DAMAGE; CELL FUNCTION; CELL RESPIRATION; CELL STIMULATION; CELL SURVIVAL; COLOSTRUM; CYSTIC FIBROSIS; DIET SUPPLEMENTATION; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG MEGADOSE; ENZYME ACTIVITY; HOST RESISTANCE; HUMAN; LIVER MITOCHONDRION; LUNG CANCER; LYMPHOCYTE; LYSOSOME; MITOCHONDRION; NEUTROPHIL; NONHUMAN; OXIDATION KINETICS; OXIDATIVE STRESS; OXYGEN TENSION; PHAGOCYTE; PROTEIN PHOSPHORYLATION; RESPIRATORY BURST; RETINOL DEFICIENCY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BETA CAROTENE; DIETARY SUPPLEMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LUNG; MITOCHONDRIA; NEUTROPHILS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RESPIRATORY BURST;

EID: 21344441240     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2005.01.009     Document Type: Review

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