Influence of the growth factors PDGF-BB, TGF-β1 and bFGF on the replicative aging of human articular chondrocytes during in vitro expansion

Journal of Orthopaedic Research

Volumn 28, Issue 3, 2010, Pages 354-360

  Brandl, Anita ^a   Angele, Peter ^a   Roll, Christina ^a   Prantl, Lucas ^a   Kujat, Richard ^a   Kinner, Bernd ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Chondrocyte; Growth factors; Replicative aging; Senescence

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; COLLAGEN TYPE 2; PLATELET DERIVED GROWTH FACTOR BB; TELOMERASE; TRANSFORMING GROWTH FACTOR BETA1;

AGED; AGING; ARTICLE; CARCINOGENESIS; CARTILAGE CELL; CASE REPORT; CELL DEDIFFERENTIATION; CELL DIVISION; CELL EXPANSION; CELL MATURATION; CELL PROLIFERATION; CELL THERAPY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HUMAN; MALE; PRIORITY JOURNAL; RESTRICTION FRAGMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TELOMERE; TISSUE ENGINEERING;

AGED; CARTILAGE, ARTICULAR; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; EXTRACELLULAR MATRIX PROTEINS; FEMALE; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; MALE; PLATELET-DERIVED GROWTH FACTOR; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RNA, MESSENGER; TELOMERASE; TELOMERE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 73949129373     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.21007     Document Type: Article

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