Insulin-like growth factor I stimulates telomerase activity in prostate cancer cells

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 7, 2003, Pages 3354-3359

  Wetterau, Lawrence A ^a   Francis, Malik J ^b   Ma, Liqun ^b   Cohen, Pinchas ^b  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b MATTEL CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SOMATOMEDIN C; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; PHOSPHORYLATION; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; RNA, MESSENGER; TELOMERASE; TUMOR CELLS, CULTURED;

EID: 0038298232     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-021326     Document Type: Article

References (53)

1. Neely EK, Beukers WM, Oh Y, Cohen P, Rosenfeld RG 1991 Insulin-like growth factor receptors. Acta Pediatr Scand 372(Suppl):116-123
2. Clemmons DR 1997 Insulin-like growth factor binding proteins and their role in controlling IGF actions. Cyt Growth Fac Rev 8:45-62
3. Wetterau LA, Moore MG, Lee KW, Shim ML, Cohen P 1999 Novel aspects of the insulin-like growth factor binding proteins. Mol Genet Metab 68:161-181
4. Pollak M 2000 Insulin-like growth factor physiology and cancer risk. Eur J Cancer 36:1224-1228
5. Katz LEL, Rosenfeld RG, Cohen P 1995 Clinical significance of insulin-like growth factor binding proteins (IGFBPs). Endocrinologist 5:36-43
6. Cohen P, Rosenfeld RG 1994 Physiologic and clinical relevance of the insulin-like growth factor binding proteins. Curr Opin Pediatr 6:462-467
7. Holt SE, Shay JW 1999 Role of telomerase in cellular proliferation and cancer. J Cell Physiol 180:10-18
8. Cong YS, Wright WE, Shay JW 2002 Human telomerase and its regulation. Micrbiol Mol Biol Rev 66:407-425
9. Blasco MA 2003 Telomeres and cancer: a tale with many endings. Curr Opin Genet Dev 13:70-76
10. Blackburn EH 1992 Telomerases. Annu Rev Biochem 61:113-129
11. Olovnikov AM 1971 Principle of marginotomy in template synthesis of polynucleotides. Doklady Biochem 201:394-397
12. Watson JD 1972 Origin of concatameric T4 DNA. Nat New Biol 239:197-201
13. Allsop RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, Greider CW, Harley CB 1992 Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 89:10114-10118
14. Harley CB, Futcher AB, Greider CW 1990 Telomeres shorten with aging. Nature 345:548-560
15. Hastie ND, Dempster M, Dunlop MG, Thompson AM, Green DK, Allshire RC 1990 Telomere reduction in human colorectal carcinoma and with ageing. Nature 346:866-868
16. Lin Y, Uemura H, Fujinami K, Hosaka M, Harada M, Kubota Y 1997 Telomerase activity in primary prostate cancer. J Urol 157:1161-1165
17. Zhang X, Mar V, Zhou W, Harrington L, Robinson MO 1999 Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Genes Dev 12:2388-2399
18. Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersberger RL, Knoll JH, Meyerson M, Weinberg RA 1999 Inhibition of telomerase limits the growth of human cancer cells. Nat Med 5:1164-1170
19. Kiaris H, Schally AV 1999 Decrease in telomerase activity in U-87MG human glioblastonras after treatment with an antagonist of growth hormone-releasing hormone. Proc Natl Acad Sci USA 96:226-231
20. Tu W, Zhang DK, Cheung PT, Tsao SW, Lau YL 1999 Effect of insulin-like growth factor 1 on PHA-stimulated cord blood mononuclear cell telomerase activity. Br J Haematol 104:785-794
21. Li H, Zhao LL, Funder JW, Liu JP 1997 Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells. J Biol Chem 272:16729-16732
22. Kang SS, Kwon T, Kwon DY, Do SI 1999 Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit. J Bio Chem 274:13085-13090
23. Bosserhoff AK, Glabl A, Stolz W, Buettner R 1997 Detection of telomerase activity in skin, melanocytic nevi, and melanoma by telomerase PCR ELISA. Biochimica 3:16-18
24. Ponte P, Ng SY, Engel J, Gunning P, Kedes L 1984 Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human β-actin cDNA. Nucleic Acids Res 12:1687-1696
25. Nakamura TM, Morin GB, Chapman KB, Weinrich SL, Andrews WH, Lingner J, Harley CB, Cech TR 1997 Telomerase catalytic subunit homologs from fission yeast and human. Science 277:955-959
26. Li H, Cao Y, Berndt MC, Funder JW, Liu JP 1999 Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro. Oncogene 18:6785-6794
27. Liu JP 1999 Studies of the molecular mechanisms in the regulation of telomerase activity. FASEB J 13:2091-2104
28. Mandal M, Kumar R 1997 Bcl-2 modulates telomerase activity. J Biol Chem 272:14183-14187
29. Kharbanda S, Kumar V, Dhar S, Pandey P, Chen C, Majumder P, Yuan ZM, Whang Y, Strauss W, Pandita TK, Weaver D, Kufe D 2000 Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase. Curr Biol 10:568-575
30. Li H, Zhao L, Yang Z, Funder JW, Liu JP 1998 Telomerase is controlled by protein kinase C α in human breast cancer cells. J Biol Chem 273:33436-33442
31. Iida A, Yamaguchi A, Hirose K 2000 Telomerase activity in colorectal cancer and its relationship to bcl-2 expression. J Surg Oncol 73:219-223
32. 3: a new class of potent inhibitors of proliferation of prostate, breast, and myeloid leukemic cells. Cancer Res 59: 4023-4029
33. Choi SH, Kang HK, Im EO, Kim YJ, Bae YT, Choi YH, Lee KH, Chung HY, Chang HK, Kim ND 2000 Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by retinoic acids. Int J Oncol 17:971-976
34. Kyo S, Takakura M, Kanaya T, Zhuo W, Fujimoto K, Nishio Y, Orimo A, Inoue M 1999 Estrogen activates telomerase. Cancer Res 59:5917-5921
35. Soda H, Raymond E, Sharma S, Lawrence R, Davidson K, Oka M, Kohno S, Izbicka E, Von Hoff DD 2000 Effects of androgens on telomerase activity in normal and malignant prostate cells in vitro. Prostate 43:161-168
36. Akiyama M, Hideshima T, Hayashi T, Tai YT, Mitsiades CS, Mitsiades N, Chauhan D, Richardson P, Munshi NC, Anderson KC 2002 Cytokines modulate telomerase activity in a human multiple myeloma cell line. Cancer Res 62:3876-3882
37. Stewart CEH, Rotwein P 1996 Growth, differentiation, survival: multiple physiological functions for insulin-like growth factors. Physiol Rev 76:1005-1026
38. Baserga R, Prisco M, Hongo A 1999 IGFs and Cell Growth. In: Rosenfeld RG, Roberts CT, eds. The IGF system: molecular biology, physiology, and clinical applications. Totowa: Humana Press; 329-353
39. Blakesly VA, Butler AA, Koval AP, Okubo Y, LeRoith D 1999 IGF-I receptor function: transducing the IGF-I signal into intracellular events. In: Rosenfeld RG, Roberts CT, eds. The IGF system: molecular biology, physiology, and clinical applications. Totowa: Humana Press; 143-163
40. Wolk A, Mantzoros CS, Andersson SO, Bergstrom R, Signorello LB, Lagiou P, Adami HO, Trichopoulos D 1998 Insulin-like growth factor-I and prostate cancer risk: a population-based, case-control study. J Natl Cancer Inst 90: 911-915
41. Chan JM, Stampfer MJ, Giovannucci E, Gann PH, Ma J, Wilinson P, Hennekens CH, Pollak M 1998 Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science 279:563-566
42. Hankinson SE, Willett WC, Colditz GA, Hunter DJ, Michaud DS, Deroo B, Rosner B, Speizer FE, Pollak M 1998 Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 351:1393-1396
43. Yu H, Spitz MR, Mistry J, Gu J, Hong WK, Wu X 1999 Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis. J Natl Cancer Inst 91:151-156
44. Ma J, Pollak MN, Giovannucci E, Chan JM, Tao Y, Hennekens CH, Stampfer MJ 1999 Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 91:620-625
45. Hiyama E, Hiyama K, Yokoyama T, Matsuura Y, Piatyszek MA, Shay JW 1995 Correlation of telomerase activity level with human neuroblastoma outcomes. Nat Med 1:249-257
46. Kim MM, Rivera MA, Botchkina IL, Shalaby R, Thor AD, Blackburn EH 2001 A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation. Proc Natl Acad Sci USA 98:7982-7987
47. Schindler A, Fiedler U, Meye A, Schmidt U, Fussel S, Pilarsky C, Herrmann J, Wirth MP 2001 Human telomerase reverse transcriptase antisense treatment downregulates the viability of prostate cancer cells in vitro. Int J Oncol 19:25-30
48. Guo C, Gerverd D, Liao R, Hamad N, Counter CM, Price DT 2001 Inhibition of telomerase is related to the life span and tumorigenicity of human prostate cancer cells. J Urol 166:694-698
49. Weng NP, Hodes R 2000 The role of telomerase expression and telomere length maintenance in human and mouse. J Clin Immunol 20:257-267
50. Mitchell JR, Wood E, Collins K 1999 A telomerase component is defective in the human disease dyskeratosis congenita. Nature 402:551-555
51. Wyllie FS, Jones CJ, Skinner JW, Haughton MF, Wallis C, Wynford-Thomas D, Faragher RG, Kipling D 2000 Telomerase prevents the accelerated cell ageing process of Werner syndrome fibroblasts. Nat Genet 24:16-17
52. Kipling D 2001 Telomeres, replicative senescence and human aging. Maturitas 38:25-38
53. Johannsson G, Svensson J, Bengtsson BA 2000 Growth hormone and ageing. Growth Horm IGF Res 10(Suppl B):S25-S30