Quantitative risk assessment relating to adventitious presence of allergens in food: A probabilistic model applied to peanut in chocolate

Risk Analysis

Volumn 30, Issue 1, 2010, Pages 7-19

  Rimbaud, Loup ^a   Heraud, Fanny ^a   La Vieille, Sébastien ^b   Leblanc, Jean Charles ^a   Crepet, Amélie ^a  

^a Health Canada ^*  (France)

^b HEALTH CANADA   (Canada)

Author keywords

Bayesian and Monte Carlo modeling; Food allergy; Quantitative risk assessment

Indexed keywords

ALLERGIC REACTIONS; BAYESIAN; BAYESIAN APPROACHES; CONSUMPTION PATTERNS; CREDIBLE INTERVAL; DOSE RESPONSE RELATIONSHIPS; EXPOSURE LEVEL; FOOD ALLERGIES; MODEL INPUTS; MONTE CARLO MODELING; MONTE CARLO SIMULATION; PEANUT PROTEINS; PROBABILISTIC MODELS; PUBLIC HEALTH; QUANTITATIVE RISK ASSESSMENT; RISK VARIABILITY; SECOND ORDERS;

ALLERGIES; ANTIGENS; BAYESIAN NETWORKS; COMPUTER SIMULATION; FOOD PRODUCTS; HEALTH RISKS; MONTE CARLO METHODS; PROTEINS; RISK MANAGEMENT; RISK PERCEPTION; UNCERTAINTY ANALYSIS;

RISK ASSESSMENT;

BAYESIAN ANALYSIS; CONSUMPTION BEHAVIOR; FOOD POISONING; FOOD SAFETY; HEALTH IMPACT; INFECTIVITY; MONTE CARLO ANALYSIS; PROTEIN; PUBLIC HEALTH; RISK ASSESSMENT;

ADULT; ANTIGENS, PLANT; ARACHIS HYPOGAEA; BAYES THEOREM; CACAO; CHILD; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FOOD CONTAMINATION; FOOD HYPERSENSITIVITY; FRANCE; HUMANS; MODELS, IMMUNOLOGICAL; MODELS, STATISTICAL; MONTE CARLO METHOD; RISK ASSESSMENT;

FRANCE;

ARACHIS HYPOGAEA;

EID: 73649099515     PISSN: 02724332     EISSN: 15396924     Source Type: Journal    
DOI: 10.1111/j.1539-6924.2009.01322.x     Document Type: Article

References (37)

1. Crevel RW, Briggs D, Hefle SL, Knulst AC, Taylor SL. Hazard characterisation in food allergen risk assessment: The application of statistical approaches and the use of clinical data. Food and Chemical Toxicology, 2007 45 (5 691 701.
2. Werfel T. Food allergy. Journal der Deutschen Dermatologischen Gesellschaft, 2008 6 (7 573 583.
3. Kanny G, Moneret-Vautrin DA, Flabbee J, Beaudouin E, Morisset M, Thevenin F. Population study of food allergy in France. Journal of Allergy and Clinical Immunology, 2001 108 (1 133 140.
4. Dutau G, Rancé F. Allergie à l'arachide. Revue Française d'allergologie et d'immunologie clinique, 2001 41 : 187 198.
5. Hourihane JOB, Grimshaw KE, Lewis SA, Briggs RA, Trewin JB, King RM, Kilburn SA, Warner JO. Does severity of low-dose, double-blind, placebo-controlled food challenges reflect severity of allergic reactions to peanut in the community? Clinical and Experimental Allergy, 2005 35 (9 1227 1233.
6. Rancé F, Grandmottet X, Grandjean H. Prevalence and main characteristics of schoolchildren diagnosed with food allergies in France. Clinical Experimental Allergy, 2005 35 (2 167 172.
7. Moneret-Vautrin DA. Epidémiologie de l'allergie alimentaire. Revue Française d'allergologie et d'immunologie clinique, 2008 48 : 171 178.
8. Röder M, Ibach A, Baltruweit I, Gruyters H, Janise A, Suwelack C, Matissek R, Vieths S, Holzhauser T. Pilot plant investigations on cleaning efficiencies to reduce hazelnut cross-contamination in industrial manufacture of cookies. Journal of Food Protection, 2008 71 (11 2263 2271.
9. Madsen CB, Hattersley S, Buck J, Gendel SM, Houben GF, Hourihane JO, Mackie A, Mills EN, Norhede P, Taylor SL, Crevel RW. Approaches to risk assessment in food allergy: Report from a workshop "developing a framework for assessing the risk from allergenic foods." Food and Chemical Toxicology, 2009 47 (2 480 489.
10. Afssa. Food allergies and advisory labelling. Maisons-Alfort: Rapports bleus de l'Afssa, Nov, 2008. Available at : http://www.afssa.fr (Opinions and Reports section).
11. Pouillot R, Miconnet N, Afchain AL, Delignette-Muller ML, Beaufort A, Rosso L, Denis JB, Cornu M. Quantitative risk assessment of Listeria monocytogenes in French cold-smoked salmon: I. Quantitative exposure assessment. Risk Analysis, 2007 27 (3 683 700.
12. Robert CP. The Bayesian Choice, 2nd ed. New York : Springer. 2001.
13. Gilks WR, Richardson S, Spiegelhalter DJ. Markov Chain Monte Carlo in Practice. London : Chapman & Hall, 1996.
14. Koppelman SJ, Vlooswijk RA, Knippels LM, Hessing M, Knol EF, van Reijsen FC, Bruijnzeel-Koomen CA. Quantification of major peanut allergens Ara h 1 and Ara h 2 in the peanut varieties Runner, Spanish, Virginia, and Valencia, bred in different parts of the world. Allergy, 2001 56 (2 132 137.
15. Pelé M, Brohee M, Anklam E, Van Hengel AJ. Peanut and hazelnut traces in cookies and chocolates: Relationship between analytical results and declaration of food allergens on product labels. Food Additives and Contaminants, 2007 24 (12 1334 1344.
16. Helsel DR. Nondetects and Data Analysis: Statistics for Censored Environmental Data, Chapter 2. Denver, CO : Wiley Interscience. 2005.
17. Afssa. Rapport de l'étude Individuelle Nationale des Consommations Alimentaires 2. Maisons-Alfort: Rapports bleus de l'Afssa, Feb, 2009. Available at : http://www.afssa.fr (Opinions and Reports section).
18. Hercberg S, Deheeger M, Preziosi P, SU-VI-MAX. Portions alimentaires. Manuel photos pour l'estimation des quantités. Editions Poly Technica, 1994.
19. Ardilly P. Les techniques de sondage. Paris : Technip, 2006, 601 607.
20. Taylor SL, Hefle SL, Bindslev-Jensen C, Atkins FM, Andre C, Bruijnzeel-Koomen C, Burks AW, Bush RK, Ebisawa M, Eigenmann PA, Host A, Hourihane JO, Isolauri E, Hill DJ, Knulst A, Lack G, Sampson HA, Moneret-Vautrin DA, Rance F, Vadas PA, Yunginger JW, Zeiger RS, Salminen JW, Madsen C, Abbott P. A consensus protocol for the determination of the threshold doses for allergenic foods: How much is too much? Clinical and Experimental Allergy, 2004 34 (5 689 695.
21. Wensing M, Penninks AH, Hefle SL, Koppelman SJ, Bruijnzeel-Koomen CA, Knulst AC. The distribution of individual threshold doses eliciting allergic reactions in a population with peanut allergy. Journal of Allergy and Clinical Immunology, 2002 110 (6 915 920.
22. INSEE (Institut National de la Statistique et des Etudes Economiques). Bilan démographique, 2008. Available at : http://www.insee.fr/fr/themes/ detail.asp?reg-id=99&ref-id=bilan-demo, Accessed on Jun 15, 2009.
23. Taylor SL, Crevel RW, Sheffield D, Kabourek J, Baumert J. Threshold dose for peanut: Risk characterization based upon published results from challenges of peanut-allergic individuals. Food and Chemical Toxicology, 2009 47 (6 1198 1204.
24. Moneret-Vautrin DA, Kanny G. Update on threshold doses of food allergens: Implications for patients and the food industry. Current Opinion in Allergy and Clinical Immunology, 2004 4 (3 215 219.
25. Kruizinga AG, Briggs D, Crevel RW, Knulst AC, Van Den Bosch LM, Houben GF. Probabilistic risk assessment model for allergens in food: Sensitivity analysis of the minimum eliciting dose and food consumption. Food and Chemical Toxicology, 2008 46 (5 1437 1443.
26. Taylor SL, Hefle SL, Bindslev-Jensen C, Bock SA, Burks AW Jr., Christie L, Hill DJ, Host A, Hourihane JO, Lack G, Metcalfe DD, Moneret-Vautrin DA, Vadas PA, Rance F, Skrypec DJ, Trautman TA, Yman IM, Zeiger RS. Factors affecting the determination of threshold doses for allergenic foods: How much is too much? Journal of Allergy and Clinical Immunology, 2002 109 (1 24 30.
27. Albert I, Grenier E, Denis JB, Rousseau J. Quantitative risk assessment from farm to fork and beyond: A global Bayesian approach concerning food-borne diseases. Risk Analysis, 2008 28 (2 557 571.
28. Holzhauser T, Vieths S. Indirect competitive ELISA for determination of traces of peanut (Arachis hypogaea L.) protein in complex food matrices. Journal of Agricultural and Food Chemistry, 1999 47 (2 603 611.
29. Stephan O, Vieths S. Development of a real-time PCR and a sandwich ELISA for detection of potentially allergenic trace amounts of peanut (Arachis hypogaea) in processed foods. Journal of Agricultural and Food Chemistry, 2004 52 (12 3754 3760.
30. Keck-Gassenmeier B, Bénet S, Rosa C, Hischenhuber C. Determination of peanut traces in food by a commercially-available ELISA test. Food and Agricultural Immunology, 1999 11 (3 243 250.
31. May CD. Objective clinical and laboratory studies of immediate hypersensitivity reactions to foods in asthmatic children. Journal of Allergy and Clinical Immunology, 1976 58 (4 500 515.
32. Bock SA, Lee WY, Remigio LK, May CD. Studies of hypersensitivity reactions to foods in infants and children. Journal of Allergy and Clinical Immunology, 1978 62 (6 327 334.
33. Nelson HS, Lahr J, Rule R, Bock A, Leung D. Treatment of anaphylactic sensitivity to peanuts by immunotherapy with injections of aqueous peanut extract. Journal of Allergy and Clinical Immunology, 1997 99 (6 Pt 1 744 751.
34. Hourihane JOB, Bedwani SJ, Dean TP, Warner JO. Randomised, double blind, crossover challenge study of allergenicity of peanut oils in subjects allergic to peanuts. BMJ, 1997 314 (7087 1084 1088.
35. Hourihane JOB, Kilburn SA, Nordlee JA, Hefle SL, Taylor SL, Warner JO. An evaluation of the sensitivity of subjects with peanut allergy to very low doses of peanut protein: A randomized, double-blind, placebo-controlled food challenge study. Journal of Allergy and Clinical Immunology, 1997 100 (5 596 600.
36. Moneret-Vautrin DA, Rancé F, Kanny G, Olsewski A, Gueant JL, Dutau G, Guérin L. Food allergy to peanuts in France - Evaluation of 142 observations. Clinical and Experimental Allergy, 1998 28 (9 1113 1119.
37. Flinterman AE, Pasmans SG, Hoekstra MO, Meijer Y, van Hoffen E, Knol EF, Hefle SL, Bruijnzeel-Koomen CA, Knulst AC. Determination of no-observed-adverse- effect levels and eliciting doses in a representative group of peanut-sensitized children. Journal of Allergy and Clinical Immunology, 2006 117 (2 448 454.