Hypoxia-induced downregulation of autophagy mediator beclin 1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis

Autophagy

Volumn 5, Issue 8, 2009, Pages 1166-1179

  Yoo, Byong Hoon ^a   Wu, Xue ^a   Derouet, Mathieu ^a   Haniff, Mehnaaz ^a   Eskelinen, Eeva Liisa ^b   Rosen, Kirill ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Apoptosis; Autophagy; Beclin 1; Caspase 9; Hypoxia

Indexed keywords

BECLIN 1; CASPASE 3; CASPASE 7; CASPASE 9; CYTOCHROME C; DEATH RECEPTOR; FAS ASSOCIATED DEATH DOMAIN PROTEIN; IRINOTECAN;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CELL ORGANELLE; CELL VACUOLE; COLORECTAL CANCER; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; EPITHELIUM CELL; FEEDBACK SYSTEM; GENETIC SUSCEPTIBILITY; HYPOXIA; MITOCHONDRION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION;

EID: 73449101095     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.5.8.10167     Document Type: Article

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