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Volumn 86, Issue 9, 2000, Pages 974-981

Hypoxia-induced endothelial apoptosis through nuclear factor-κb (NF- κb)-mediated bcl-2 suppression: In vivo evidence of the importance of NF-κb in endothelial cell regulation

Author keywords

Bax; bcl 2; Decoy; Hypoxia; Nuclear factor B

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; PYRROLIDINE DITHIOCARBAMATE; UNCLASSIFIED DRUG;

EID: 19244370521     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.86.9.974     Document Type: Article
Times cited : (171)

References (47)
  • 2
    • 0029147782 scopus 로고
    • Induction of interleukin-6 synthesis in the myocardium: Potential role in postreperfusion inflammatory injury
    • Kukielka GL, Smith CW, Manning AM, Youker KA, Michael LH, Entman ML. Induction of interleukin-6 synthesis in the myocardium: potential role in postreperfusion inflammatory injury. Circulation. 1995; 92:1866-1875.
    • (1995) Circulation , vol.92 , pp. 1866-1875
    • Kukielka, G.L.1    Smith, C.W.2    Manning, A.M.3    Youker, K.A.4    Michael, L.H.5    Entman, M.L.6
  • 4
    • 0028843589 scopus 로고
    • Cytokine mRNA expression in postischemic/reperfused myocardium
    • Herskowitz A, Choi S, Ansari AA, Wesselingh S. Cytokine mRNA expression in postischemic/reperfused myocardium. Am J Pathol. 1995; 146:419-428.
    • (1995) Am J Pathol. , vol.146 , pp. 419-428
    • Herskowitz, A.1    Choi, S.2    Ansari, A.A.3    Wesselingh, S.4
  • 5
    • 0028302691 scopus 로고
    • Molecular evidence for induction of intracellular adhesion molecule-1 in the viable border zone associated with ischemia-reperfusion injury of the dog heart
    • Youker KA, Hawkins HK, Kukielka GL, Perrard JL, Michael LH, Ballantyne CM, Smith CW, Entman ML. Molecular evidence for induction of intracellular adhesion molecule-1 in the viable border zone associated with ischemia-reperfusion injury of the dog heart. Circulation. 1994;89:2736-2746.
    • (1994) Circulation , vol.89 , pp. 2736-2746
    • Youker, K.A.1    Hawkins, H.K.2    Kukielka, G.L.3    Perrard, J.L.4    Michael, L.H.5    Ballantyne, C.M.6    Smith, C.W.7    Entman, M.L.8
  • 6
    • 0024475227 scopus 로고
    • NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control
    • Lenardo MJ, Baltimore D. NF-κB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell. 1989;58:227-229.
    • (1989) Cell , vol.58 , pp. 227-229
    • Lenardo, M.J.1    Baltimore, D.2
  • 7
    • 0025642663 scopus 로고
    • Regulation of gene expression with double-stranded phosphorothioate oligonucleotides
    • Bielinska A, Schivdasani RA, Zhang L, Nabel GJ. Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science. 1990;250:997-100.
    • (1990) Science , vol.250 , pp. 997-1100
    • Bielinska, A.1    Schivdasani, R.A.2    Zhang, L.3    Nabel, G.J.4
  • 9
    • 0032103247 scopus 로고    scopus 로고
    • Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular disease
    • Morishita R, Higaki J, Tomita N, Ogihara T. Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular disease. Circ Res. 1998;82:1023-1028.
    • (1998) Circ Res. , vol.82 , pp. 1023-1028
    • Morishita, R.1    Higaki, J.2    Tomita, N.3    Ogihara, T.4
  • 11
    • 0031938280 scopus 로고    scopus 로고
    • Nuclear factor-κB contributes to excitotoxin-induced apoptosis in rat striatum
    • Qin ZH, Wang Y, Nakai M, Chase TN. Nuclear factor-κB contributes to excitotoxin-induced apoptosis in rat striatum. Mol Pharmacol. 1998;53: 33-42.
    • (1998) Mol Pharmacol. , vol.53 , pp. 33-42
    • Qin, Zh.1    Wang, Y.2    Nakai, M.3    Chase, T.N.4
  • 13
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science. 1998;281:1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin A.S., Jr.5
  • 14
    • 0028300301 scopus 로고
    • The emerging concept of vascular remodeling
    • Gibbons GH, Dzau VJ. The emerging concept of vascular remodeling. N Engl J Med. 1994;30:1431-1438.
    • (1994) N Engl J Med. , vol.30 , pp. 1431-1438
    • Gibbons, G.H.1    Dzau, V.J.2
  • 15
    • 0026525559 scopus 로고
    • Angiogenesis in skeletal and cardiac muscle
    • Hudlicka O, Brown M, Egginton S. Angiogenesis in skeletal and cardiac muscle. Physiol Rev. 1992;72:369-417.
    • (1992) Physiol Rev. , vol.72 , pp. 369-417
    • Hudlicka, O.1    Brown, M.2    Egginton, S.3
  • 17
    • 0020584163 scopus 로고
    • Culture of quiescent arterial smooth muscle cells in a defined serum-free medium
    • Libby P, O'Brien KV. Culture of quiescent arterial smooth muscle cells in a defined serum-free medium. J Cell Physiol. 1983;115:217-223.
    • (1983) J Cell Physiol. , vol.115 , pp. 217-223
    • Libby, P.1    O'Brien, K.V.2
  • 18
    • 0021821903 scopus 로고
    • Involvement of the bcl-2 gene in human follicular lymphoma
    • Tsujimoto Y, Cossman J, Jaffe E, Croce CM. Involvement of the bcl-2 gene in human follicular lymphoma. Science. 1985;228:1440-1443.
    • (1985) Science , vol.228 , pp. 1440-1443
    • Tsujimoto, Y.1    Cossman, J.2    Jaffe, E.3    Croce, C.M.4
  • 19
  • 21
    • 0028860108 scopus 로고
    • Fas antigen and bcl-2 expression on lymphocytes cultured with cytomegalovirus and varicellazoster virus antigen
    • Ito M, Watanabe M, Ihara T, Kamiya H, Sakurai M. Fas antigen and bcl-2 expression on lymphocytes cultured with cytomegalovirus and varicellazoster virus antigen. Cell Immunol. 1995;160:173-177.
    • (1995) Cell Immunol. , vol.160 , pp. 173-177
    • Ito, M.1    Watanabe, M.2    Ihara, T.3    Kamiya, H.4    Sakurai, M.5
  • 23
    • 0029841890 scopus 로고    scopus 로고
    • Characterization of in vivo gene transfer into the arterial wall mediated by the Sendai virus (hemagglutinating virus of Japan) liposomes: An effective tool for the in vivo study of arterial diseases
    • Yonemitsu Y, Kaneda Y, Morishita R, Nakagawa K, Nakashima Y, Sueishi K. Characterization of in vivo gene transfer into the arterial wall mediated by the Sendai virus (hemagglutinating virus of Japan) liposomes: an effective tool for the in vivo study of arterial diseases. Lab Invest. 1996;75:313-323.
    • (1996) Lab Invest. , vol.75 , pp. 313-323
    • Yonemitsu, Y.1    Kaneda, Y.2    Morishita, R.3    Nakagawa, K.4    Nakashima, Y.5    Sueishi, K.6
  • 24
    • 0031581171 scopus 로고    scopus 로고
    • Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): Reciprocal effect of cationic lipid for in vitro and in vivo gene transfer
    • Saeki Y, Matsumoto N, Nakano Y, Mori M, Awai K, Kaneda Y. Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): reciprocal effect of cationic lipid for in vitro and in vivo gene transfer. Hum Gene Ther. 1997;8:2133-2141.
    • (1997) Hum Gene Ther. , vol.8 , pp. 2133-2141
    • Saeki, Y.1    Matsumoto, N.2    Nakano, Y.3    Mori, M.4    Awai, K.5    Kaneda, Y.6
  • 25
    • 0030873144 scopus 로고    scopus 로고
    • HVJ (Sendai virus)-cationic liposomes: A novel and potentially effective liposome-mediated technique for gene transfer to the airway epithelium
    • Yonemitsu Y, Kaneda Y, Muraishi A, Yoshizumi T, Sugimachi K, Sueishi K. HVJ (Sendai virus)-cationic liposomes: a novel and potentially effective liposome-mediated technique for gene transfer to the airway epithelium. Gene Ther. 1997;4:631-638.
    • (1997) Gene Ther. , vol.4 , pp. 631-638
    • Yonemitsu, Y.1    Kaneda, Y.2    Muraishi, A.3    Yoshizumi, T.4    Sugimachi, K.5    Sueishi, K.6
  • 26
  • 27
    • 0029150785 scopus 로고
    • Inhibition of tumor necrosis factor induced human aortic endothelial cell adhesion molecule gene expression by an alkoxybenzo[b]thiophene-2-carboxamide
    • Wolle J, Ferguson E, Keshava C, Devall LJ, Boschelli DH, Newton RS, Saxena U. Inhibition of tumor necrosis factor induced human aortic endothelial cell adhesion molecule gene expression by an alkoxybenzo[b]thiophene-2-carboxamide. Biochem Biophys Res Commun. 1995;214:6-10.
    • (1995) Biochem Biophys Res Commun. , vol.214 , pp. 6-10
    • Wolle, J.1    Ferguson, E.2    Keshava, C.3    Devall, L.J.4    Boschelli, D.H.5    Newton, R.S.6    Saxena, U.7
  • 28
    • 0033592288 scopus 로고    scopus 로고
    • Inhibition of NF-κB activation by pyrrolidine dithiocarbamate prevents in vivo expression of proinflammatory genes
    • Liu SF, Ye X, Malik AB. Inhibition of NF-κB activation by pyrrolidine dithiocarbamate prevents in vivo expression of proinflammatory genes. Circulation. 1999;100:1330-1337.
    • (1999) Circulation , vol.100 , pp. 1330-1337
    • Liu, S.F.1    Ye, X.2    Malik, A.B.3
  • 30
    • 0028040019 scopus 로고
    • Bcl-2 and ihe regulation of programmed cell death
    • Reed JC. Bcl-2 and ihe regulation of programmed cell death. J Cell Biol. 1994;124:1-6.
    • (1994) J Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 31
    • 0027164220 scopus 로고
    • In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury
    • Weyrich AS, Ma XY, Lefer DJ, Albertine KH, Lefer AM. In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury. J Clin Invest. 1993;91: 2620-2629.
    • (1993) J Clin Invest. , vol.91 , pp. 2620-2629
    • Weyrich, A.S.1    Ma, X.Y.2    Lefer, D.J.3    Albertine, K.H.4    Lefer, A.M.5
  • 32
    • 0028063279 scopus 로고
    • Myocardial protective effect and its mechanism of leukocyte-depleted reperfusion in neonatal rabbit hearts
    • Sawa Y, Nakano S, Shimazaki Y, Nishimura M, Kuratani T, Matsuda H. Myocardial protective effect and its mechanism of leukocyte-depleted reperfusion in neonatal rabbit hearts. Ann Thorac Surg. 1994;58: 1386-1391.
    • (1994) Ann Thorac Surg. , vol.58 , pp. 1386-1391
    • Sawa, Y.1    Nakano, S.2    Shimazaki, Y.3    Nishimura, M.4    Kuratani, T.5    Matsuda, H.6
  • 33
    • 0030946393 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cells induce programmed cell death in human endothelial cells and may prevent repair: Role of cytokines
    • Lindner H, Holler E, Ertl B, Multhoff G, Schreglmann M, Klauke I, Schultz-Hector S, Eissner G. Peripheral blood mononuclear cells induce programmed cell death in human endothelial cells and may prevent repair: role of cytokines. Blood. 1997;89:1931-1938.
    • (1997) Blood , vol.89 , pp. 1931-1938
    • Lindner, H.1    Holler, E.2    Ertl, B.3    Multhoff, G.4    Schreglmann, M.5    Klauke, I.6    Schultz-Hector, S.7    Eissner, G.8
  • 35
    • 0028912505 scopus 로고
    • Induction of apoptosis at different oxygen tensions: Evidence that oxygen radicals do not mediate apoptotic signaling
    • Muschel RJ, Bernhard EJ, Garza L, McKenna WG, Koch CJ. Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling. Cancer Res. 1995;55:995-998.
    • (1995) Cancer Res. , vol.55 , pp. 995-998
    • Muschel, R.J.1    Bernhard, E.J.2    Garza, L.3    McKenna, W.G.4    Koch, C.J.5
  • 36
    • 0031875852 scopus 로고    scopus 로고
    • Ox-LDL induces apoptosis in human coronary artery endothelial cells: Role of PKC, PTK, bcl-2, and Fas
    • Li D, Yang B, Mehta JL. Ox-LDL induces apoptosis in human coronary artery endothelial cells: role of PKC, PTK, bcl-2, and Fas. Am J Physiol. 1998;275:H568-H576.
    • (1998) Am J Physiol. , vol.275
    • Li, D.1    Yang, B.2    Mehta, J.L.3
  • 37
    • 0031956685 scopus 로고    scopus 로고
    • Biphasic regulation of transcription factor nuclear factor-κB activity in human endothelial cells by lysophosphatidylcholine through protein kinase C-mediated pathway
    • Sugiyama S, Kugiyama K, Ogata N, Doi H, Ota Y, Ohgushi M, Matsumura T, Oka H, Yasue H. Biphasic regulation of transcription factor nuclear factor-κB activity in human endothelial cells by lysophosphatidylcholine through protein kinase C-mediated pathway. Arterioscler Thromb Vasc Biol. 1998;18:568-576.
    • (1998) Arterioscler Thromb Vasc Biol. , vol.18 , pp. 568-576
    • Sugiyama, S.1    Kugiyama, K.2    Ogata, N.3    Doi, H.4    Ota, Y.5    Ohgushi, M.6    Matsumura, T.7    Oka, H.8    Yasue, H.9
  • 38
    • 0033192573 scopus 로고    scopus 로고
    • Oxidant stress regulation of IL-8 and ICAM-1 gene expression: Differential activation and binding of the transcription factors AP-1 and NF-κB
    • Roebuck KA. Oxidant stress regulation of IL-8 and ICAM-1 gene expression: differential activation and binding of the transcription factors AP-1 and NF-κB. Int J Mol Med. 1999;4:223-230.
    • (1999) Int J Mol Med. , vol.4 , pp. 223-230
    • Roebuck, K.A.1
  • 41
    • 0029999656 scopus 로고    scopus 로고
    • Bcl-2 down-regulates the activity of transcription factor NF-κB induced upon apoptosis
    • Grimm S, Bauer MK, Baeuerle PA, Schulze-Osthoff K. Bcl-2 down-regulates the activity of transcription factor NF-κB induced upon apoptosis. J Cell Biol. 1996;134:13-23.
    • (1996) J Cell Biol. , vol.134 , pp. 13-23
    • Grimm, S.1    Bauer, M.K.2    Baeuerle, P.A.3    Schulze-Osthoff, K.4
  • 42
    • 0033557372 scopus 로고    scopus 로고
    • Bcl-2 and Bel-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-κB
    • Badrichani AZ, Stroka DM, Bilbao G, Curiel DT, Bach FH, Ferran C. Bcl-2 and Bel-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-κB. J Clin Invest. 1999;103:543-553.
    • (1999) J Clin Invest. , vol.103 , pp. 543-553
    • Badrichani, A.Z.1    Stroka, D.M.2    Bilbao, G.3    Curiel, D.T.4    Bach, F.H.5    Ferran, C.6
  • 43
    • 0032848297 scopus 로고    scopus 로고
    • Linkage of the BH4 domain of Bcl-2 and the nuclear factor κB signaling pathway for suppression of apoptosis
    • de Moissac D, Zheng H, Kirshenbaum LA. Linkage of the BH4 domain of Bcl-2 and the nuclear factor κB signaling pathway for suppression of apoptosis. J Biol Chem. 1999;274:29505-29509.
    • (1999) J Biol Chem. , vol.274 , pp. 29505-29509
    • De Moissac, D.1    Zheng, H.2    Kirshenbaum, L.A.3
  • 44
    • 0345561544 scopus 로고    scopus 로고
    • Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NF-κB activation in primary hippocampal neurons
    • Tamatani M, Che YH, Matsuzaki H, Ogawa S, Okado H, Miyake S, Mizuno T, Tohyama M. Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NF-κB activation in primary hippocampal neurons. J Biol Chem. 1999;274:8531-8538.
    • (1999) J Biol Chem. , vol.274 , pp. 8531-8538
    • Tamatani, M.1    Che, Y.H.2    Matsuzaki, H.3    Ogawa, S.4    Okado, H.5    Miyake, S.6    Mizuno, T.7    Tohyama, M.8
  • 46
    • 0033141406 scopus 로고    scopus 로고
    • NF-κB to the rescue: RELs, apoptosis and cellular transformation
    • Foo SY, Nolan GP. NF-κB to the rescue: RELs, apoptosis and cellular transformation. Trends Genet. 1999;15:229-235.
    • (1999) Trends Genet. , vol.15 , pp. 229-235
    • Foo, S.Y.1    Nolan, G.P.2
  • 47
    • 0031594280 scopus 로고    scopus 로고
    • TNFα regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation
    • Sata M, Walsh K. TNFα regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation. Nat Med. 1998; 4:415-420.
    • (1998) Nat Med. , vol.4 , pp. 415-420
    • Sata, M.1    Walsh, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.