Progress and prospects of chitosan and its derivatives as non-viral gene vectors in gene therapy

Current Gene Therapy

Volumn 9, Issue 6, 2009, Pages 495-502

  Tong, Haijun ^a   Shi, Qin ^b   Fernandes, Julio C ^b   Liu, Li ^c   Dai, Kerong ^a   Zhang, Xiaoling ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Biological reconstruction; Chemical modification; Chitosan siRNA complex; Rate limiting step

Indexed keywords

AURINTRICARBOXYLIC ACID; CHITOSAN; CHITOSAN DERIVATIVE; DNA; DNA VACCINE; FOLIC ACID; GAMMA INTERFERON; INTERLEUKIN 12; NANOPARTICLE; PLASMID DNA; SMALL INTERFERING RNA;

CELL NUCLEUS; CELL SPECIFICITY; CHEMICAL MODIFICATION; COMPLEX FORMATION; CYTOPLASM; ELECTROPORATION; ENDOCYTOSIS; ENDOSOME; FEASIBILITY STUDY; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HYDRODYNAMICS BASED TRANSFECTION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PROTEIN DOMAIN; REVIEW; RNA INTERFERENCE;

BIOCOMPATIBLE MATERIALS; CHITOSAN; DNA; GENE THERAPY; GENETIC VECTORS; HUMANS; KINETICS; RNA, SMALL INTERFERING;

EID: 73449085169     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652309790031111     Document Type: Review

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