Nonviral gene delivery systems: From simple transfection agents to artificial viruses

Drug Discovery Today: Technologies

Volumn 2, Issue 1, 2005, Pages 103-109

  Mastrobattista, Enrico ^a   Bravo, Silvina A ^a   van der Aa, Marieke ^a   Crommelin, Daan J A ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; NUCLEIC ACID; PLASMID DNA; POLYMER; SYNTHETIC PEPTIDE; VIRUS PROTEIN; VIRUS VECTOR;

ARTICLE; BIOENGINEERING; BREAST CANCER; DISEASE CARRIER; DNA BINDING; DNA PACKAGING; DNA VECTOR; DRUG UPTAKE; GENE EXPRESSION REGULATION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC ENGINEERING; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; IMMUNOGENICITY; NANOTECHNOLOGY; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; NUCLEAR LOCALIZATION SIGNAL; PARTICLE SIZE; RECEPTOR BINDING; SURFACE CHARGE; VIRAL GENE DELIVERY SYSTEM; VIRUS PARTICLE;

EID: 21744461896     PISSN: 17406749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddtec.2005.04.002     Document Type: Review

References (41)

1. C.E. Thomas et al. Progress and problems with the use of viral vectors for gene therapy Nat. Rev. Genet. 4 2003 346-358
2. E. Check A tragic setback Nature 420 2002 116-118
3. C.E. Smull and E.H. Ludwig Enhancement of the plaque-forming capacity of poliovirus ribonucleic acid with basic proteins J. Bacteriol. 84 1962 1035-1040
4. M. Ehrlich et al. Interaction of microbial DNA with cultured mammalian cells. Binding of the donor DNA to the cell surface Biochim. Biophys. Acta 454 1976 397-409
5. A.G. Schatzlein Targeting of synthetic gene delivery systems J. Biomed. Biotechnol. 2003 2003 149-158
6. M. Ogris et al. Tumor-targeted gene therapy: Strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes J. Control. Release 91 2003 173-181
7. R. Kircheis et al. Tumor targeting with surface-shielded ligand - polycation DNA complexes J. Control. Release 72 2001 165-170
8. D. Lechardeur et al. Intracellular routing of plasmid DNA during non-viral gene transfer Adv. Drug Deliv. Rev. 57 2005 755-767
9. J. Rejman et al. Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis Biochem. J. 377 Pt 1 2004 159-169
10. M.E. Dowty et al. Plasmid DNA entry into postmitotic nuclei of primary rat myotubes Proc. Natl. Acad. Sci. U.S.A. 92 1995 4572-4576
11. E. Dauty and A.S. Verkman Actin cytoskeleton as the principal determinant of size-dependent DNA mobility in cytoplasm: A new barrier for non-viral gene delivery J. Biol. Chem. 280 9 2005 7823-7828
12. N. Pante and M. Kann Nuclear pore complex is able to transport macromolecules with diameters of about 39 nm Mol. Biol. Cell 13 2002 425-434
13. M.R. Capecchi High efficiency transformation by direct microinjection of DNA into cultured mammalian cells Cell 22 Pt 2 1980 479-488
14. A.E. Smith and A. Helenius How viruses enter animal cells Science 304 2004 237-242
15. P.L. Stewart et al. Structural basis of nonenveloped virus cell entry Adv. Protein Chem. 64 2003 455-491
16. D.J. FitzGerald et al. Adenovirus-induced release of epidermal growth factor and pseudomonas toxin into the cytosol of KB cells during receptor-mediated endocytosis Cell 32 1983 607-617
17. G.R. Whittaker and A. Helenius Nuclear import and export of viruses and virus genomes Virology 246 1998 1-23
18. E. Wagner et al. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle Proc. Natl. Acad. Sci. U.S.A. 89 1992 7934-7938
19. L.K. Medina-Kauwe et al. Nonviral gene delivery to human breast cancer cells by targeted Ad5 penton proteins Gene Ther. 8 2001 1753-1761
20. L. Vaysse et al. Development of a self-assembling nuclear targeting vector system based on the tetracycline repressor protein J. Biol. Chem. 279 2004 5555-5564
21. M.A. Zanta et al. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus Proc. Natl. Acad. Sci. U.S.A. 96 1999 91-96
22. M.A. van der Aa et al. An NLS peptide covalently linked to linear DNA does not enhance transfection efficiency of cationic polymer based gene delivery systems J. Gene Med. 7 2004 208-217
23. A. Aris et al. Exploiting viral cell-targeting abilities in a single polypeptide, non-infectious, recombinant vehicle for integrin-mediated DNA delivery and gene expression Biotechnol. Bioeng. 68 2000 689-696
24. H. Peluffo et al. Nonviral gene delivery to the central nervous system based on a novel integrin-targeting multifunctional protein Hum. Gene Ther. 14 2003 1215-1223
25. R.L. Garcea and L. Gissmann Virus-like particles as vaccines and vessels for the delivery of small molecules Curr. Opin. Biotechnol. 15 2004 513-517
26. H. Petry et al. The use of virus-like particles for gene transfer Curr. Opin. Mol. Ther. 5 2003 524-528
27. S. Gleiter and H. Lilie Cell-type specific targeting and gene expression using a variant of polyoma VP1 virus-like particles Biol. Chem. 384 2003 247-255
28. N. Krauzewicz et al. Virus-like gene transfer into cells mediated by polyoma virus pseudocapsids Gene Ther. 7 2000 2122-2131
29. K. Tegerstedt et al. Murine pneumotropic virus VP1 virus-like particles (VLPs) bind to several cell types independent of sialic acid residues and do not serologically cross react with murine polyomavirus VP1 VLPs J. Gen. Virol. 84 Pt 12 2003 3443-3452
30. N. Krauzewicz et al. Sustained ex vivo and in vivo transfer of a reporter gene using polyoma virus pseudocapsids Gene Ther. 7 2000 1094-1102
31. B. Clark et al. Immunity against both polyomavirus VP1 and a transgene product induced following intranasal delivery of VP1 pseudocapsid-DNA complexes J. Gen. Virol. 82 Pt 11 2001 2791-2797
32. C. Goldmann et al. Molecular cloning and expression of major structural protein VP1 of the human polyomavirus JC virus: Formation of virus-like particles useful for immunological and therapeutic studies J. Virol. 73 1999 4465-4469
33. Y. Eto et al. Neutralizing antibody evasion ability of adenovirus vector induced by the bioconjugation of methoxypolyethylene glycol succinimidyl propionate (MPEG-SPA) Biol. Pharm. Bull. 27 2004 936-938
34. H. Mok et al. Evaluation of polyethylene glycol modification of first-generation and helper-dependent adenoviral vectors to reduce innate immune responses Mol. Ther. 11 2005 66-79
35. J.M. Lord et al. Toxin entry: How bacterial proteins get into mammalian cells Cell. Microbiol. 1 1999 85-91
36. C. Uherek and W. Wels DNA-carrier proteins for targeted gene delivery Adv. Drug Deliv. Rev. 44 2000 153-166
37. C. Uherek et al. A modular DNA carrier protein based on the structure of diphtheria toxin mediates target cell-specific gene delivery J. Biol. Chem. 273 1998 8835-8841
38. A.J. Chirino et al. Minimizing the immunogenicity of protein therapeutics Drug Discov. Today 9 2004 82-90
39. K. Lundstrom Latest development in viral vectors for gene therapy Trends Biotechnol. 21 2003 117-122
40. C.M. Roth and S. Sundaram Engineering synthetic vectors for improved DNA delivery: Insights from intracellular pathways Annu. Rev. Biomed. Eng. 6 2004 397-426
41. A. Aris and A. Villaverde Modular protein engineering for non-viral gene therapy Trends Biotechnol. 22 2004 371-377