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Volumn 9, Issue 3, 2009, Pages 172-180

Role of PI3K/AKT, cPLA2 and ERK1/2 signaling pathways in insulin regulation of vascular smooth muscle cells proliferation

Author keywords

cPLA2; ERK1 2; Insulin; PI3K Akt; Proliferation; VSMCs

Indexed keywords

CYTOSOLIC PHOSPHOLIPASE A2; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B;

EID: 73249149543     PISSN: 1871529X     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152909789007034     Document Type: Review
Times cited : (44)

References (86)
  • 1
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross, R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature, 1993, 362, 801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 3
    • 0037092995 scopus 로고    scopus 로고
    • Diabetes and atherosclerosis: Epidemiology, pathophysiology, and management
    • Beckman, J.A.; Creager, M.A.; Libby, P. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA, 2, 287, 2570-2581.
    • JAMA , vol.2 , Issue.287 , pp. 2570-2581
    • Beckman, J.A.1    Creager, M.A.2    Libby, P.3
  • 4
    • 0343485089 scopus 로고    scopus 로고
    • Insulin resistance syndrome predicts the risk of coronary heart disease and stroke in healthy middle-aged men: The 22-year follow up results of the Helsinki Policemen Study
    • Pyorala, M.; Miettinen, H.; Halonen, P.; Laakso, M.; Pyorala, K. Insulin resistance syndrome predicts the risk of coronary heart disease and stroke in healthy middle-aged men: the 22-year follow up results of the Helsinki Policemen Study. Arterioscler. Thromb. Vasc. Biol., 2000, 20, 538-544.
    • (2000) Arterioscler. Thromb. Vasc. Biol , vol.20 , pp. 538-544
    • Pyorala, M.1    Miettinen, H.2    Halonen, P.3    Laakso, M.4    Pyorala, K.5
  • 5
  • 6
    • 0034767113 scopus 로고    scopus 로고
    • Molecular mechanism of insulin resistance in type 2 diabetes mellitus: Role of the insulin receptor variant forms
    • Sesti, G.; Federici, M.; Lauro, D.; Sbraccia, P.; Lauro, R. Molecular mechanism of insulin resistance in type 2 diabetes mellitus: role of the insulin receptor variant forms. Diabetes Metab. Res. Rev., 2001, 17, 363-373.
    • (2001) Diabetes Metab. Res. Rev , vol.17 , pp. 363-373
    • Sesti, G.1    Federici, M.2    Lauro, D.3    Sbraccia, P.4    Lauro, R.5
  • 7
    • 0022549829 scopus 로고
    • Studies of the human liver insulin receptor in noninsulin-dependent diabetes mellitus
    • Arner, P.; Einarsson, K.; Ewerth, S.; Livingston, J. Studies of the human liver insulin receptor in noninsulin-dependent diabetes mellitus. J. Clin. Invest., 1986, 77, 1716-1718.
    • (1986) J. Clin. Invest , vol.77 , pp. 1716-1718
    • Arner, P.1    Einarsson, K.2    Ewerth, S.3    Livingston, J.4
  • 8
    • 0035159865 scopus 로고    scopus 로고
    • Insulin resistance: Cellular and clinical concepts
    • Cefalu, W.T. Insulin resistance: cellular and clinical concepts. Exp. Biol. Med.(Maywood), 2001, 226, 13-26.
    • (2001) Exp. Biol. Med.(Maywood) , vol.226 , pp. 13-26
    • Cefalu, W.T.1
  • 9
    • 37549022688 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • De Luca, C.; Olefsky, M.J. Inflammation and insulin resistance. FEBS Lett., 2007, 582, 97-105.
    • (2007) FEBS Lett , vol.582 , pp. 97-105
    • De Luca, C.1    Olefsky, M.J.2
  • 10
    • 56149119340 scopus 로고    scopus 로고
    • Reducing cardiovascular complications of type 2 diabetes by targeting multiple risk factors
    • Reasner, C.A. Reducing cardiovascular complications of type 2 diabetes by targeting multiple risk factors. J. Cardiovasc. Pharmacol., 2008, 52, 136-144.
    • (2008) J. Cardiovasc. Pharmacol , vol.52 , pp. 136-144
    • Reasner, C.A.1
  • 11
    • 0027240295 scopus 로고
    • Cytokines and smooth muscle cells in atherosclerosis
    • Nilsson, J. Cytokines and smooth muscle cells in atherosclerosis. Cardiovasc. Res., 1993, 27, 1184-1190.
    • (1993) Cardiovasc. Res , vol.27 , pp. 1184-1190
    • Nilsson, J.1
  • 12
    • 0028824908 scopus 로고
    • Diabetes mellitus and associated hypertension, vascular disease, and nephropathy. An update
    • Sowers, J.R.; Epstein, M. Diabetes mellitus and associated hypertension, vascular disease, and nephropathy. An update. Hypertension, 1995, 26, 869-879.
    • (1995) Hypertension , vol.26 , pp. 869-879
    • Sowers, J.R.1    Epstein, M.2
  • 15
    • 0026671405 scopus 로고
    • Insulin and atherogenesis
    • Stout, R.W. Insulin and atherogenesis. Eur. J. Epidemiol., 1992, 8 (Suppl 1), 134-135.
    • (1992) Eur. J. Epidemiol , vol.8 , Issue.SUPPL. 1 , pp. 134-135
    • Stout, R.W.1
  • 16
    • 0020681210 scopus 로고
    • Differential responsiveness to insulin of endothelial and support cells from micro- and macrovessels
    • King, G.L.; Buzney, S.M.; Kahn, C.R.; Hetu, N.; Buchwald, S.; Macdonald, S.G.; Rand, L.I. Differential responsiveness to insulin of endothelial and support cells from micro- and macrovessels. J. Clin. Invest., 1983, 71, 974-979.
    • (1983) J. Clin. Invest , vol.71 , pp. 974-979
    • King, G.L.1    Buzney, S.M.2    Kahn, C.R.3    Hetu, N.4    Buchwald, S.5    Macdonald, S.G.6    Rand, L.I.7
  • 17
    • 0025894102 scopus 로고
    • Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities
    • Bornfeldt, K.E.; Gidlof, R.A.; Wasteson, A.; Lake, M.; Skottner, A.; Arnqvist, H.J. Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities. Diabetologia, 1991, 34, 307-313.
    • (1991) Diabetologia , vol.34 , pp. 307-313
    • Bornfeldt, K.E.1    Gidlof, R.A.2    Wasteson, A.3    Lake, M.4    Skottner, A.5    Arnqvist, H.J.6
  • 18
    • 0021814480 scopus 로고
    • Characterization of the receptors for insulin and the insulin-like growth factors on micro- and macrovascular tissues
    • Jialal, I.; Crettaz, M.; Hachiya, H.L.; Kahn, C.R.; Moses, A.C.; Buzney, S.M.; King, G.L. Characterization of the receptors for insulin and the insulin-like growth factors on micro- and macrovascular tissues. Endocrinology, 1985, 117, 1222-1229.
    • (1985) Endocrinology , vol.117 , pp. 1222-1229
    • Jialal, I.1    Crettaz, M.2    Hachiya, H.L.3    Kahn, C.R.4    Moses, A.C.5    Buzney, S.M.6    King, G.L.7
  • 19
    • 0033780678 scopus 로고    scopus 로고
    • Circulating IGF-I concentrations are low and not correlated to glycaemic control in adults with type 1 diabetes
    • Ekman, B.; Nystrom, F.; Arnqvist, H.J. Circulating IGF-I concentrations are low and not correlated to glycaemic control in adults with type 1 diabetes. Eur. J. Endocrinol., 2000, 143, 505-510.
    • (2000) Eur. J. Endocrinol , vol.143 , pp. 505-510
    • Ekman, B.1    Nystrom, F.2    Arnqvist, H.J.3
  • 21
    • 0038293353 scopus 로고    scopus 로고
    • Insulin signalling pathways in aorta and muscle from two animal models of insulin resistance--the obese middle-aged and the spontaneously hypertensive rats
    • Zecchin, H.G.; Bezerra, R.M.; Carvalheira, J.B.; Carvalho-Filho, M.A.; Metze, K.; Franchini, K.G.; Saad, M.J. Insulin signalling pathways in aorta and muscle from two animal models of insulin resistance--the obese middle-aged and the spontaneously hypertensive rats. Diabetologia, 2003, 46, 479-491.
    • (2003) Diabetologia , vol.46 , pp. 479-491
    • Zecchin, H.G.1    Bezerra, R.M.2    Carvalheira, J.B.3    Carvalho-Filho, M.A.4    Metze, K.5    Franchini, K.G.6    Saad, M.J.7
  • 23
    • 0009805746 scopus 로고    scopus 로고
    • Vascular insulin/insulin-like growth factor-1 resistance in female obese Zucker rats
    • Walsh, M.F.; Ali, S.S.; Sowers, J.R. Vascular insulin/insulin-like growth factor-1 resistance in female obese Zucker rats. Metabolism, 2001, 50, 607-612.
    • (2001) Metabolism , vol.50 , pp. 607-612
    • Walsh, M.F.1    Ali, S.S.2    Sowers, J.R.3
  • 25
    • 10644281006 scopus 로고    scopus 로고
    • Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c
    • Kim, K.H.; Song, M.J.; Yoo, E.J.; Choe, S.S.; Park, S.D.; Kim, J.B. Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c. J. Biol. Chem., 2004, 279, 51999-52006.
    • (2004) J. Biol. Chem , vol.279 , pp. 51999-52006
    • Kim, K.H.1    Song, M.J.2    Yoo, E.J.3    Choe, S.S.4    Park, S.D.5    Kim, J.B.6
  • 26
    • 33845398283 scopus 로고    scopus 로고
    • Transcriptional regulation by insulin: From the receptor to the gene
    • Mounier, C.; Posner, B.I. Transcriptional regulation by insulin: from the receptor to the gene. Can. J. Physiol. Pharmacol., 2006, 84, 713-724.
    • (2006) Can. J. Physiol. Pharmacol , vol.84 , pp. 713-724
    • Mounier, C.1    Posner, B.I.2
  • 28
    • 10044271037 scopus 로고    scopus 로고
    • SREBP transcription factors: Master regulators of lipid homeostasis
    • Eberle, D.; Hegarty, B.; Bossard, P.; Ferre, P.; Foufelle, F. SREBP transcription factors: master regulators of lipid homeostasis. Biochimie, 2004, 86, 839-848.
    • (2004) Biochimie , vol.86 , pp. 839-848
    • Eberle, D.1    Hegarty, B.2    Bossard, P.3    Ferre, P.4    Foufelle, F.5
  • 30
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering, B.M.; Coffer, P.J. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature, 1995, 376, 599-602.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 31
    • 0026095665 scopus 로고
    • A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
    • Bellacosa, A.; Testa, J.R.; Staal, S.P.; Tsichlis, P.N. A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region. Science, 1991, 254, 274-277.
    • (1991) Science , vol.254 , pp. 274-277
    • Bellacosa, A.1    Testa, J.R.2    Staal, S.P.3    Tsichlis, P.N.4
  • 32
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley, L.C. The phosphoinositide 3-kinase pathway. Science, 2002, 296, 1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 33
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross, D.A.; Alessi, D.R.; Cohen, P.; Andjelkovich, M.; Hemmings, B.A. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature, 1995, 378, 785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 38
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: Insights into insulin action
    • Taniguchi, C.M.; Emanuelli, B.; Kahn, C.R. Critical nodes in signalling pathways: insights into insulin action. Nat. Rev. Mol. Cell Biol., 2006, 7, 85-96.
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 41
    • 33845711358 scopus 로고    scopus 로고
    • Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway
    • Shiojima, I.; Walsh, K. Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway. Genes Dev., 2006, 20, 3347-3365.
    • (2006) Genes Dev , vol.20 , pp. 3347-3365
    • Shiojima, I.1    Walsh, K.2
  • 42
    • 33646178955 scopus 로고    scopus 로고
    • Reciprocal relationships between insulin resistance and endothelial dysfunction: Molecular and pathophysiological mechanisms
    • Kim, J.A.; Montagnani, M.; Koh, K.K.; Quon, M.J. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation, 2006, 113, 1888-1904.
    • (2006) Circulation , vol.113 , pp. 1888-1904
    • Kim, J.A.1    Montagnani, M.2    Koh, K.K.3    Quon, M.J.4
  • 44
    • 0034130439 scopus 로고    scopus 로고
    • Recent advances in the regulation of cytosolic phospholipase A(2)
    • Gijon, M.A.; Spencer, D.M.; Leslie, C.C. Recent advances in the regulation of cytosolic phospholipase A(2). Adv. Enzyme Regul., 2000, 40, 255-268.
    • (2000) Adv. Enzyme Regul , vol.40 , pp. 255-268
    • Gijon, M.A.1    Spencer, D.M.2    Leslie, C.C.3
  • 45
    • 0038399752 scopus 로고    scopus 로고
    • Chakraborti, S. Phospholipase A(2) isoforms: a perspective. Cell Signal., 2003, 15, 637-665.
    • Chakraborti, S. Phospholipase A(2) isoforms: a perspective. Cell Signal., 2003, 15, 637-665.
  • 46
    • 0025174365 scopus 로고
    • Group II phospholipase A2 mRNA synthesis is stimulated by two distinct mechanisms in rat vascular smooth muscle cells
    • Nakano, T.; Ohara, O.; Teraoka, H.; Arita, H. Group II phospholipase A2 mRNA synthesis is stimulated by two distinct mechanisms in rat vascular smooth muscle cells. FEBS Lett., 1990, 261, 171-174.
    • (1990) FEBS Lett , vol.261 , pp. 171-174
    • Nakano, T.1    Ohara, O.2    Teraoka, H.3    Arita, H.4
  • 48
    • 34249730961 scopus 로고    scopus 로고
    • Regulation of the inducible nitric oxide synthase and sodium pump in type 1 diabetes
    • Zakula, Z.; Koricanac, G.; Putnikovic, B.; Markovic, L.; Isenovic, E.R. Regulation of the inducible nitric oxide synthase and sodium pump in type 1 diabetes. Med. Hypotheses, 2007, 69, 302-306.
    • (2007) Med. Hypotheses , vol.69 , pp. 302-306
    • Zakula, Z.1    Koricanac, G.2    Putnikovic, B.3    Markovic, L.4    Isenovic, E.R.5
  • 49
    • 0025107548 scopus 로고
    • Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937
    • Clark, J.D.; Milona, N.; Knopf, J.L. Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937. Proc. Natl. Acad. Sci. USA, 1990, 87, 7708-7712.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7708-7712
    • Clark, J.D.1    Milona, N.2    Knopf, J.L.3
  • 50
    • 0030610012 scopus 로고    scopus 로고
    • Identity between the Ca2+-independent phospholipase A2 enzymes from P388D1 macrophages and Chinese hamster ovary cells
    • Balboa, M.A.; Balsinde, J.; Jones, S.S.; Dennis, E.A. Identity between the Ca2+-independent phospholipase A2 enzymes from P388D1 macrophages and Chinese hamster ovary cells. J. Biol. Chem., 1997, 272, 8576-8580.
    • (1997) J. Biol. Chem , vol.272 , pp. 8576-8580
    • Balboa, M.A.1    Balsinde, J.2    Jones, S.S.3    Dennis, E.A.4
  • 51
    • 0030964780 scopus 로고    scopus 로고
    • A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs
    • Tang, J.; Kriz, R.W.; Wolfman, N.; Shaffer, M.; Seehra, J.; Jones, S.S. A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs. J. Biol. Chem., 1997, 272, 8567-8575.
    • (1997) J. Biol. Chem , vol.272 , pp. 8567-8575
    • Tang, J.1    Kriz, R.W.2    Wolfman, N.3    Shaffer, M.4    Seehra, J.5    Jones, S.S.6
  • 52
    • 0025922172 scopus 로고
    • The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells
    • Kramer, R.M.; Roberts, E.F.; Manetta, J.; Putnam, J.E. The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells. J. Biol. Chem., 1991, 266, 5268-5272.
    • (1991) J. Biol. Chem , vol.266 , pp. 5268-5272
    • Kramer, R.M.1    Roberts, E.F.2    Manetta, J.3    Putnam, J.E.4
  • 53
    • 0025895754 scopus 로고
    • Inflammatory factors stimulate expression of group II phospholipase A2 in rat cultured astrocytes. Two distinct pathways of the gene expression
    • Oka, S.; Arita, H. Inflammatory factors stimulate expression of group II phospholipase A2 in rat cultured astrocytes. Two distinct pathways of the gene expression. J. Biol. Chem., 1991, 266, 9956-9960.
    • (1991) J. Biol. Chem , vol.266 , pp. 9956-9960
    • Oka, S.1    Arita, H.2
  • 54
    • 0032617299 scopus 로고    scopus 로고
    • Interleukin-1beta regulation of inducible nitric oxide synthase and cyclooxygenase-2 involves the p42/44 and p38 MAPK signaling pathways in cardiac myocytes
    • LaPointe, M.C.; Isenovic, E. Interleukin-1beta regulation of inducible nitric oxide synthase and cyclooxygenase-2 involves the p42/44 and p38 MAPK signaling pathways in cardiac myocytes. Hypertension, 1999, 33, 276-282.
    • (1999) Hypertension , vol.33 , pp. 276-282
    • LaPointe, M.C.1    Isenovic, E.2
  • 57
    • 0026786084 scopus 로고
    • Enzymic activities of two-chain pepsinogen, two-chain pepsin, and the amino-terminal lobe of pepsinogen
    • Lin, X.L.; Lin, Y.Z.; Koelsch, G.; Gustchina, A.; Wlodawer, A.; Tang, J. Enzymic activities of two-chain pepsinogen, two-chain pepsin, and the amino-terminal lobe of pepsinogen. J. Biol. Chem., 1992, 267, 17257-17263.
    • (1992) J. Biol. Chem , vol.267 , pp. 17257-17263
    • Lin, X.L.1    Lin, Y.Z.2    Koelsch, G.3    Gustchina, A.4    Wlodawer, A.5    Tang, J.6
  • 58
    • 0027050565 scopus 로고
    • Macrophage colony stimulating factor activates phosphatidylcholine hydrolysis by cytoplasmic phospholipase A2
    • Nakamura, T.; Lin, L.L.; Kharbanda, S.; Knopf, J.; Kufe, D. Macrophage colony stimulating factor activates phosphatidylcholine hydrolysis by cytoplasmic phospholipase A2. EMBO J., 1992, 11, 4917-4922.
    • (1992) EMBO J , vol.11 , pp. 4917-4922
    • Nakamura, T.1    Lin, L.L.2    Kharbanda, S.3    Knopf, J.4    Kufe, D.5
  • 59
    • 0141866848 scopus 로고    scopus 로고
    • Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways
    • Wang, C.C.; Gurevich, I.; Draznin, B. Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways. Diabetes, 2003, 52, 2562-2569.
    • (2003) Diabetes , vol.52 , pp. 2562-2569
    • Wang, C.C.1    Gurevich, I.2    Draznin, B.3
  • 60
    • 0030777901 scopus 로고    scopus 로고
    • Inhibition of MAP kinase blocks insulin-mediated DNA synthesis and transcriptional activation of c-fos by Elk-1 in vascular smooth muscle cells
    • Xi, X.P.; Graf, K.; Goetze, S.; Hsueh, W.A.; Law, R.E. Inhibition of MAP kinase blocks insulin-mediated DNA synthesis and transcriptional activation of c-fos by Elk-1 in vascular smooth muscle cells. FEBS Lett, 1997, 417, 283-286.
    • (1997) FEBS Lett , vol.417 , pp. 283-286
    • Xi, X.P.1    Graf, K.2    Goetze, S.3    Hsueh, W.A.4    Law, R.E.5
  • 61
    • 0028970042 scopus 로고
    • Cell biology of atherosclerosis
    • Ross, R. Cell biology of atherosclerosis. Annu. Rev. Physiol., 1995, 57, 791-804.
    • (1995) Annu. Rev. Physiol , vol.57 , pp. 791-804
    • Ross, R.1
  • 62
    • 61349124153 scopus 로고    scopus 로고
    • A novel hypothesis regarding the possible involvement of cytosolic phospholipase 2 in insulin-stimulated proliferation of vascular smooth muscle cells
    • Isenovic, E.R.; Fretaud, M.; Dobutovic, B.; Sudar, E.; Smiljanic, K.; Zaric, B.; Trpkovic, A.; Marche, P. A novel hypothesis regarding the possible involvement of cytosolic phospholipase 2 in insulin-stimulated proliferation of vascular smooth muscle cells. Cell Biol. Int., 2009, 33, 386-392.
    • (2009) Cell Biol. Int , vol.33 , pp. 386-392
    • Isenovic, E.R.1    Fretaud, M.2    Dobutovic, B.3    Sudar, E.4    Smiljanic, K.5    Zaric, B.6    Trpkovic, A.7    Marche, P.8
  • 63
    • 0032898857 scopus 로고    scopus 로고
    • The insulin signaling pathway
    • Taha, C.; Klip, A. The insulin signaling pathway. J. Membr. Biol., 1999, 169, 1-12.
    • (1999) J. Membr. Biol , vol.169 , pp. 1-12
    • Taha, C.1    Klip, A.2
  • 64
    • 0025823448 scopus 로고    scopus 로고
    • Boulton, T.G.; Nye, S.H.; Robbins, D.J.; Ip, N.Y.; Radziejewska, E.; Morgenbesser, S.D.; DePinho, R.A.; Panayotatos, N.; Cobb, M.H.; Yancopoulos, G.D. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell, 1991, 65, 663-675.
    • Boulton, T.G.; Nye, S.H.; Robbins, D.J.; Ip, N.Y.; Radziejewska, E.; Morgenbesser, S.D.; DePinho, R.A.; Panayotatos, N.; Cobb, M.H.; Yancopoulos, G.D. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell, 1991, 65, 663-675.
  • 65
    • 0027257212 scopus 로고
    • Insulin activates p21Ras and guanine nucleotide releasing factor in cells expressing wild type and mutant insulin receptors
    • Draznin, B.; Chang, L., Leitner, J.W., Takata, Y., Olefsky, J.M. Insulin activates p21Ras and guanine nucleotide releasing factor in cells expressing wild type and mutant insulin receptors. J. Biol. Chem., 1993, 268, 19998-20001.
    • (1993) J. Biol. Chem , vol.268 , pp. 19998-20001
    • Draznin, B.1    Chang, L.2    Leitner, J.W.3    Takata, Y.4    Olefsky, J.M.5
  • 66
    • 0032582808 scopus 로고    scopus 로고
    • Differentiated phenotype of smooth muscle cells depends on signaling pathways through insulin-like growth factors and phosphatidylinositol 3-kinase
    • Hayashi, K.; Saga, H.; Chimori, Y.; Kimura, K.; Yamanaka, Y.; Sobue,K. Differentiated phenotype of smooth muscle cells depends on signaling pathways through insulin-like growth factors and phosphatidylinositol 3-kinase. J. Biol. Chem., 1998, 273, 28860-28867.
    • (1998) J. Biol. Chem , vol.273 , pp. 28860-28867
    • Hayashi, K.1    Saga, H.2    Chimori, Y.3    Kimura, K.4    Yamanaka, Y.5    Sobue, K.6
  • 67
    • 14044275116 scopus 로고    scopus 로고
    • Role of L-type calcium channel blocking in epidermal growth factor receptor-independent activation of extracellular signal regulated kinase 1/2
    • Yin, X.; Polidano, E.; Faverdin, C.; Marche, P. Role of L-type calcium channel blocking in epidermal growth factor receptor-independent activation of extracellular signal regulated kinase 1/2. J. Hypertens., 2005, 23, 337-350.
    • (2005) J. Hypertens , vol.23 , pp. 337-350
    • Yin, X.1    Polidano, E.2    Faverdin, C.3    Marche, P.4
  • 68
    • 7944232490 scopus 로고    scopus 로고
    • Ang II attenuates IGF-1-stimulated Na+, K(+)-ATPase activity via PI3K/Akt pathway in vascular smooth muscle cells
    • Isenovic, E.R.; Meng, Y.; Jamali, N.; Milivojevic, N.; Sowers, J.R. Ang II attenuates IGF-1-stimulated Na+, K(+)-ATPase activity via PI3K/Akt pathway in vascular smooth muscle cells. Int. J. Mol. Med., 2004, 13, 915-922.
    • (2004) Int. J. Mol. Med , vol.13 , pp. 915-922
    • Isenovic, E.R.1    Meng, Y.2    Jamali, N.3    Milivojevic, N.4    Sowers, J.R.5
  • 69
    • 0036739920 scopus 로고    scopus 로고
    • Progression of atheroma: A struggle between death andprocreation
    • Geng,Y.J.;Libby, P. Progression of atheroma: a struggle between death andprocreation.Arterioscler.Thromb. Vasc.Biol.,2002, 22, 1370-1380.
    • (2002) Arterioscler.Thromb. Vasc.Biol , vol.22 , pp. 1370-1380
    • Geng, Y.J.1    Libby, P.2
  • 70
    • 0030793795 scopus 로고    scopus 로고
    • Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: Implications for glucose metabolism
    • Shepherd, P.R.; Nave, B.T.; Rincon, J.; Haigh, R.J.; Foulstone, E.; Proud, C.; Zierath, J.R.; Siddle, K.; Wallberg-Henriksson, H. Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism. Diabetologia, 1997, 40, 1172-1177.
    • (1997) Diabetologia , vol.40 , pp. 1172-1177
    • Shepherd, P.R.1    Nave, B.T.2    Rincon, J.3    Haigh, R.J.4    Foulstone, E.5    Proud, C.6    Zierath, J.R.7    Siddle, K.8    Wallberg-Henriksson, H.9
  • 71
    • 61349124153 scopus 로고    scopus 로고
    • A novel hypothesis regarding the possible involvement of cytosolic phospholipase 2 in insulin-stimulated proliferation of vascular smooth muscle cells
    • Isenovic, E.R.; Fretaud, M.; Dobutovic, B.; Sudar, E.; Smiljanic, K.; Zaric, B.; Trpkovic, A.; Marche, P. A novel hypothesis regarding the possible involvement of cytosolic phospholipase 2 in insulin-stimulated proliferation of vascular smooth muscle cells. Cell Biol. Int., 2009, 33(3), 386-392.
    • (2009) Cell Biol. Int , vol.33 , Issue.3 , pp. 386-392
    • Isenovic, E.R.1    Fretaud, M.2    Dobutovic, B.3    Sudar, E.4    Smiljanic, K.5    Zaric, B.6    Trpkovic, A.7    Marche, P.8
  • 72
    • 0031775644 scopus 로고    scopus 로고
    • The additive effects of glucose and insulin on the proliferation of infragenicular vascular smooth muscle cells
    • discussion 1038-1039
    • Avena, R.; Mitchell, M.E.; Neville, R.F.; Sidawy, A.N. The additive effects of glucose and insulin on the proliferation of infragenicular vascular smooth muscle cells. J. Vasc. Surg., 1998, 28, 1033-1038; discussion 1038-1039.
    • (1998) J. Vasc. Surg , vol.28 , pp. 1033-1038
    • Avena, R.1    Mitchell, M.E.2    Neville, R.F.3    Sidawy, A.N.4
  • 73
    • 0034674650 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibits insulin-induced mitogenic signaling in vascular smooth muscle cells
    • Goetze, S.; Kintscher, U.; Kawano, H.; Kawano, Y.; Wakino, S.; Fleck, E.; Hsueh, W.A.; Law, R.E. Tumor necrosis factor alpha inhibits insulin-induced mitogenic signaling in vascular smooth muscle cells. J. Biol. Chem., 2000, 275, 18279-18283.
    • (2000) J. Biol. Chem , vol.275 , pp. 18279-18283
    • Goetze, S.1    Kintscher, U.2    Kawano, H.3    Kawano, Y.4    Wakino, S.5    Fleck, E.6    Hsueh, W.A.7    Law, R.E.8
  • 74
    • 0034864881 scopus 로고    scopus 로고
    • Endogenous angiotensin II suppresses insulin signaling in vascular smooth muscle cells from spontaneously hypertensive rats
    • Fukuda, N.; Satoh, C.; Hu, W.Y.; Nakayama, M.; Kishioka, H.; Kanmatsuse, K. Endogenous angiotensin II suppresses insulin signaling in vascular smooth muscle cells from spontaneously hypertensive rats. J. Hypertens., 2001, 19, 1651-1658.
    • (2001) J. Hypertens , vol.19 , pp. 1651-1658
    • Fukuda, N.1    Satoh, C.2    Hu, W.Y.3    Nakayama, M.4    Kishioka, H.5    Kanmatsuse, K.6
  • 76
    • 0036612880 scopus 로고    scopus 로고
    • Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells
    • Silfani, T.N.; Freeman, E.J. Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells. Arch. Biochem. Biophys., 2002, 402, 84-93.
    • (2002) Arch. Biochem. Biophys , vol.402 , pp. 84-93
    • Silfani, T.N.1    Freeman, E.J.2
  • 77
    • 0030810224 scopus 로고    scopus 로고
    • Cytosolic 85-kDa phospholipase A2-mediated release of arachidonic acid is critical for proliferation of vascular smooth muscle cells
    • Anderson, K.M.; Roshak, A.; Winkler, J.D.; McCord, M.; Marshall, L.A. Cytosolic 85-kDa phospholipase A2-mediated release of arachidonic acid is critical for proliferation of vascular smooth muscle cells. J. Biol. Chem., 1997, 272, 30504-30511.
    • (1997) J. Biol. Chem , vol.272 , pp. 30504-30511
    • Anderson, K.M.1    Roshak, A.2    Winkler, J.D.3    McCord, M.4    Marshall, L.A.5
  • 78
    • 0033137354 scopus 로고    scopus 로고
    • The effect of phospholipase A2 inhibitors on proliferation and apoptosis of murine intestinal cells
    • Longo, W.E.; Grossmann, E.M.; Erickson, B.; Panesar, N.; Mazuski, J.E.; Kaminski, D.L. The effect of phospholipase A2 inhibitors on proliferation and apoptosis of murine intestinal cells. J. Surg. Res., 1999, 84, 51-56.
    • (1999) J. Surg. Res , vol.84 , pp. 51-56
    • Longo, W.E.1    Grossmann, E.M.2    Erickson, B.3    Panesar, N.4    Mazuski, J.E.5    Kaminski, D.L.6
  • 80
    • 0031909202 scopus 로고    scopus 로고
    • II-induced translocation of cytosolic PLA2 to the nucleus in vascular smooth muscle cells
    • Freeman, E.J.; Ruehr, M.L.; Dorman, R.V. ANG II-induced translocation of cytosolic PLA2 to the nucleus in vascular smooth muscle cells. Am. J. Physiol., 1998, 274, C282-288.
    • (1998) Am. J. Physiol , vol.274
    • Freeman, E.J.1    Ruehr, M.L.2    Dorman, R.V.A.3
  • 81
    • 0032514708 scopus 로고    scopus 로고
    • 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin- dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells
    • Muthalif, M.M.; Benter, I.F.; Karzoun, N.; Fatima, S.; Harper, J.; Uddin, M.R.; Malik, K.U. 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin- dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. Proc. Natl. Acad. Sci. USA, 1998, 95, 12701-12706.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12701-12706
    • Muthalif, M.M.1    Benter, I.F.2    Karzoun, N.3    Fatima, S.4    Harper, J.5    Uddin, M.R.6    Malik, K.U.7
  • 82
    • 47249135717 scopus 로고    scopus 로고
    • Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin-induced smooth muscle cell proliferation
    • Gluck, N.; Schwob, O.; Krimsky, M.; Yedgar, S. Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin-induced smooth muscle cell proliferation. Am. J. Physiol. Cell Physiol., 2008, 294, C1597-1603.
    • (2008) Am. J. Physiol. Cell Physiol , vol.294
    • Gluck, N.1    Schwob, O.2    Krimsky, M.3    Yedgar, S.4
  • 83
    • 0030858836 scopus 로고    scopus 로고
    • Angiotensin II activates phosphatidylinositol 3-kinaseinvascular smoothmuscle cells
    • Saward, L.; Zahradka, P. Angiotensin II activates phosphatidylinositol 3-kinaseinvascular smoothmuscle cells. Circ. Res., 1997, 81, 249-257.
    • (1997) Circ. Res , vol.81 , pp. 249-257
    • Saward, L.1    Zahradka, P.2
  • 84
    • 0028451703 scopus 로고
    • Insulin-induced Ca2+ transport is altered in vascular smooth muscle cells of spontaneously hypertensive rats
    • Touyz, R.M.; Schiffrin, E.L. Insulin-induced Ca2+ transport is altered in vascular smooth muscle cells of spontaneously hypertensive rats. Hypertension, 1994, 23, 931-935.
    • (1994) Hypertension , vol.23 , pp. 931-935
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 85
    • 0030575539 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase and the regulation of cell growth
    • Carpenter,C.L.; Cantley, L.C. Phosphoinositide 3-kinase and the regulation of cell growth. Biochim. Biophys. Acta, 1996, 1288, M11-16.
    • (1996) Biochim. Biophys. Acta , vol.1288
    • Carpenter, C.L.1    Cantley, L.C.2
  • 86
    • 0026340995 scopus 로고
    • Phosphoinositide 3-kinase: A new effector in signal transduction?
    • Downes, C.P.; Carter, A.N. Phosphoinositide 3-kinase: a new effector in signal transduction? Cell Signal., 1991, 3, 501-513.
    • (1991) Cell Signal , vol.3 , pp. 501-513
    • Downes, C.P.1    Carter, A.N.2


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