Tissue-specific impairment of insulin signaling in vasculature and skeletal muscle of fructose-fed rats

Hypertension Research

Volumn 26, Issue 2, 2003, Pages 169-176

  Hyakukoku, Masaya ^a   Higashiura, Katsuhiro ^a   Ura, Nobuyuki ^a   Murakami, Hideyuki ^a   Yamaguchi, Koichi ^a   Wang, Ling ^a   Furuhashi, Masato ^a   Togashi, Nobuhiko ^a   Shimamoto, Kazuaki ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Atherosclerosis; Extracellular regulated protein kinase; Insulin receptor subunit; Insulin receptor substrate 1; Insulin resistance

Indexed keywords

FRUCTOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P42; PROTEIN P44; THREONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; BETA CHAIN; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; HYPERINSULINEMIA; HYPERTENSION; INSULIN RESISTANCE; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SOLEUS MUSCLE; THORACIC AORTA; TISSUE SPECIFICITY; VASCULARIZATION;

ANIMALS; AORTA, THORACIC; DIETARY SUCROSE; FRUCTOSE; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SKELETAL; PHOSPHOPROTEINS; PHOSPHORYLCHOLINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; THREONINE; TYROSINE;

EID: 0037300437     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.26.169     Document Type: Article

References (32)

1. Hongyan T, Aiqun M, Chongmin L, Mailing C: Correlative factors of insulin resistance in essential hypertension. Hypertens Res 2000; 23: 265-270.
2. Ginsberg HN: Insulin resistance and cardiovascular disease. J Clin Invest 2000; 106: 453-458.
3. Egan BM, Greene EL, Goodfriend TL: Insulin resistance and cardiovascular disease. Am J Hypertens 2001; 14: 116S-125S.
4. DeFronzo RA: Insulin resistance, hyperinsulinemia and coronary artery disease. J Cardiovasc Pharmacol 1992; 20 (Suppl 1): S1-S16.
5. Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M: Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. J Biol Chem 1994; 269: 3568-3573.
6. Folli F, Saad MJA, Backer JM, Kahn R: Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat. J Biol Chem 1992; 267: 22171-22177.
7. Backer JM, Myers MG Jr, Shoelson SE, et al: Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation. EMBO J 1992; 11: 3469-3479.
8. Begum N, Song Y, Rienzie J, Ragolia L: Vascular smooth muscle cell growth and insulin regulation of mitogen-activated protein kinase in hypertension. Am J Physiol 1998; 275: C42-C49.
9. Jiang ZY, Lin YW, Clemont A, et al: Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats. J Clin Invest 1999; 104: 447-457.
10. Li Y, Higashiura K, Ura N, et al: Effects of the Chinese medicine TSJN on insulin resistance and hypertension in fructose-fed rats. Hypertens Res 2000; 23: 101-107.
11. Pitre M, Nadeau A, Bachelard H: Insulin sensitivity and hemodynamic responses to insulin in Wistar-Kyoto and spontaneously hypertensive rats. Am J Physiol 1996; 271: E658-E668.
12. Anai M, Funaki M, Ogihara T, et al: Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats. Diabetes 1998; 47: 13-23.
13. Yamauchi T, Tobe K, Tamemoto H: Insulin signaling and insulin actions in the muscle and livers of insulin-resistant, insulin receptor substrate 1-deficient mice. Mol Cell Biol 1996; 16: 3074-3084.
14. Mayes PA: Intermediary metabolism of fructose. Am J Clin Nutr 1993; 58 (Suppl): 754S-765S.
15. Hwang IS, Ho H, Hoffman BB, Reaven GM: Fructose-induced insulin resistance and hypertension in rats. Hypertension 1987; 10: 512-516.
16. Higashiura K, Ura N, Takada T, et al: Alteration of muscle fiber composition linking to insulin resistance and hypertension in fructose-fed rats. Am J Hypertens 1999; 12: 596-602.
17. Bezerra RMN, Ueno M, Silva MS, Tavares DQ, Carvalho CRO, Saad MJA: A high fructose diet affects the early steps of insulin action in muscle and liver of rats. J Nutr 2000;130:1531-1535.
18. Reaven GM: Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607.
19. Roden M, Price TB, Perseghin G, et al: Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 1996; 97: 2859-2865.
20. Dresner A, Laurent D, Marcucci M, et al: Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J Clin Invest 1999; 103: 253-259.
21. Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF Spiegelman BM: IRS-1 mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α and obesity-induced insulin resistance. Science 1996; 271: 665-668.
22. Folli F, Kahn CR, Hansen H, Bouchie JL, Feener EP: Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. J Clin Invest 1997; 100: 2158-2169.
23. Elbaz N, Bedecs K, Masson M, Sutren M, Strosberg AD, Nahmias C: Functional trans-inactivation of insulin receptor kinase by growth-inhibitory angiotensin II AT2 receptor. Mol Endocrinol 2000; 14: 795-804.
24. Togashi N, Ura N, Higashiura. K, Murakami H, Shimamoto K: The contribution of skeletal muscle tumor necrosis factor-α to insulin resistance and hypertension in fructose-fed rats. J Hypertens 2000; 18: 1605-1610.
25. Stephens JM, Lee J, Pilch PF: Tumor necrosis factor-α-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction. J Biol Chem 1997; 272: 971-976.
26. Griffin ME, Marcucci MJ, Cline GW, et al: Free fatty acid-induced insulin resistance is associated with activation of protein kinase Cθ and alterations in the insulin signaling cascade. Diabetes 1999; 48: 1270-1274.
27. Folli F, Saad MJA, Velloso L, et al: Crosstalk between insulin and angiotensin II signaling systems. Exp Clin Endocrinol Diabetes 1999; 107: 133-139.
28. Higashiura K, Ura N, Takada T, et al: The effects of an angiotensin-converting enzyme inhibitor and an angiotensin II receptor antagonist on insulin resistance in fructose-fed rats. Am J Hypertens 2000; 13: 290-297.
29. Hsueh WA, Law RE: Insulin signaling in the arterial wall. Am J Cardiol 1999; 84: 21J-24J.
30. Pfeifle B, Ditschuneit H: Effect of insulin on growth of cultured human arterial smooth muscle cells. Diabetologia 1981; 20: 155-158.
31. Howard G, O'Leary DH, Zaccaro D, et al: Insulin sensitivity and atherosclerosis. Circulation 1996; 93: 1809-1817.
32. Tsuchihashi K, Hikita N, Hase M: Role of hyperinsulinemia in atherosclerotic coronary arterial disease: studies of semi-quantitative coronary angiography. Intern Med 1999; 38: 691-697.